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Gary Kase Tate, London, Central London, ON (2025)

08/01/2025

The trip became very worthwhile and it was great to interact with endocrinology colleagues that I don't usually see. 🎉🤓🙌🏻

08/01/2025

We were thrilled to introduce our brand refresh to 73 talented content creators and host an insightful talk with in her beautiful salon. Followed by introducing The Organic Pharmacy to 45 pharmacists, who had an opportunity to delve deeper into the science behind our formulations and clinical results. 🔬

08/01/2025

Why is 𝐒𝐓𝐃𝐄𝐈® 𝐆𝐋𝐏-𝟏 𝐖𝐞𝐢𝐠𝐡𝐭 𝐋𝐨𝐬𝐬 𝐎𝐫𝐚𝐥 𝐒𝐨𝐥𝐮𝐭𝐢𝐨𝐧 your great choice?
✅ Blood Sugar Regulation – Helps stabilize blood sugar levels, reducing spikes and crashes.
✅ Appetite Control – Naturally curbs cravings and supports portion control.
✅ Metabolic Health – Enhances fat burning and promotes a healthy metabolism.
✅ Anti-Aging – Combats oxidative stress, supporting cellular repair and longevity.
✅ Liver Health – Aids in detoxification and supports optimal liver function.
✅ Immune Boosting (Cold Prevention) – Strengthens immunity, reducing the risk of infections.
✅ Memory Enhancement – Improves cognitive function and supports brain health.
✅ Gut Health – Balances digestion, promotes gut flora, and alleviates bloating and discomfort.
✅ Safe & Effective: Made with natural ingredients and a science-backed formula, our oral liquid is MHRA- and GMP-certified for quality and safety. It supports metabolism, blood sugar balance, appetite control, and healthy fat loss, promoting overall vitality.

08/01/2025

It’s been such an interesting day. I’m excited to learn more about what I can do to promote people’s health. Advocacy is key, and it needs to come from those who are truly practicing medicine!

08/01/2025

Overall Obesity Statistics in the United Kingdom
In England alone apart from the 24.9% of purely obese patients, another significant percentage number of 61.7% are either obese or overweight. Another recent study says that the current obesity levels that are prevalent today are three times of what was prevalent during the 1980’s. During then a significantly small number of just 6% men and 8% women were reported to be obese.
In a recent study they concluded at the University of Oxford that, “overweight kids are most likely to become obese adults.” Another study reveals that obesity is more prevalent among the poor neighborhoods of London, which is contrary to the common belief. Factors like Income, ethnicity and social deprivation have a significant relation to the number of cases that come up every year related to obesity.
Statistics Among Men
Obesity is quite prevalent among British men with a significant number, 22.1%, being obese which the second highest n the world is after Malta. What is surprising is that the figures are far from declining and the statistical institutes have predicted that the number of obese men in the United Kingdom will go up to 36% of people by 2030.
Statistics Among Women
The statistics among women are not pleasant as well, with one out of twelve British women are termed as Clinically Obese. The number of overweight or obese has become an alarming 59%. If this trend continues, as more and more women are falling under the category of obese and overweight the numbers will reach up to 64% by the year 2030.

08/01/2025

What is Lymphatic Obstruction? Associated Health Risks
Lymphatic obstruction is a common health issue that can lead to the accumulation of toxins in the body, triggering a cascade of adverse effects. One major consequence is the buildup of body fat and fluid retention. When lymphatic flow is disrupted, toxins are not effectively cleared from the tissues, impairing cellular function, slowing metabolism, and increasing the risk of weight gain and edema..

08/01/2025

Storage and Breakdown of Fat
Fats in food consumed by the body are broken down during digestion into fatty acids and glycerol, which enter the bloodstream and are transported throughout the body. Excess fatty acids are synthesized into triglycerides in the liver and fat cells and then stored. When we consume too many calories, the body stores this excess fat as adipose tissue for use during times of high energy demand.
Storage: When we eat, fat is broken down in the intestines, and fatty acids and glycerol enter the bloodstream. They are transported through the bloodstream to adipose tissue, where they are converted into triglycerides and stored in fat cells. This process is regulated by hormones such as insulin, which prompts fat cells to combine fatty acids and glycerol to form triglycerides and store them.
Catabolism: Fat stores are mobilized when the body needs energy (e.g., during exercise or hunger). Hormones such as adrenaline and noradrenaline activate lipolytic enzymes in fat cells that begin to break down stored triglycerides into fatty acids.
Release and Transport of Fatty Acids
Broken-down fatty acids are transported through the bloodstream to the liver, muscles, and other tissues that use fatty acids as an energy source. Fatty acids can be transported where they are needed for energy via fatty acid-binding proteins (FABP) and plasma proteins such as albumin.
Muscles: During exercise, muscle cells have a high energy demand, especially during aerobic exercise, and fat becomes an important energy source. Fatty acids enter the muscle cell and are broken down into carbon dioxide and water through the process of "beta-oxidation" in the mitochondria, which also releases ATP (cellular energy).
Liver: Fatty acids also enter the liver, where liver cells convert them through fatty acid oxidation into ketone bodies, which serve as an energy source for the brain and other tissues, especially during long periods of fasting or on a low-carbohydrate diet like the ketogenic diet.
β-Oxidation (Process of Fatty Acid Oxidation)
In the cells, fatty acids enter the mitochondria and undergo β-oxidation, which is the primary catabolic process for fatty acids. Each oxidation process removes two carbon atoms to create an acetyl-coenzyme A (acetyl-CoA). These acetyl-coenzyme A molecules enter the tricarboxylic acid cycle (also known as the Krebs cycle) and ultimately pass through the respiratory chain to produce ATP. This process is the central step in the energy-providing process for fats.
Production and Use of Ketone Bodies
When the body is exposed to prolonged fasting or low carbohydrate intake, the liver converts fatty acids into ketone bodies. Ketone bodies (including acetoacetic acid, beta-hydroxybutyric acid, and acetone) are a highly efficient energy source, especially for the brain. Normally, the brain relies primarily on glucose, but during periods of starvation, it uses ketone bodies as an alternative energy source.
Regulation of Fat Metabolism
Fat metabolism is regulated by a variety of hormones and enzymes. Here are some key regulators:
Insulin: Insulin is the main storage hormone in fat metabolism. When blood sugar levels are high, insulin secretion increases, promoting fat storage. Insulin inhibits lipolysis and helps store energy as fat.
Epinephrine and Norepinephrine: These hormones are released in response to stress, exercise, or hunger and promote the breakdown of fat, releasing fatty acids into the bloodstream.
Growth Hormone: This hormone is important during childhood growth; it also helps with the breakdown of fat and promotes the release of fatty acids.
Testosterone and Estrogen: S*x hormones also affect fat distribution and metabolism. For example, testosterone contributes to fat burning, while estrogen can promote fat storage in certain areas, such as the thighs and buttocks.

08/01/2025

We're diving into the fascinating world of the endocrine system, and how glands work is incredibly important, especially when it comes to weight management, metabolism, and overall health.
First, let's talk about glands: exocrine vs. endocrine.
You'll see two types of glands in the diagram:
1. Exocrine Glands (Left)
Think of these as your body's "product-based secretions." They release their products (such as sweat, saliva, and digestive enzymes) through ducts to specific locations, such as the surface of your skin or inside your digestive tract.
For example: Salivary glands (in your mouth) release saliva through ducts to help break down food. Exocrine cells in the pancreas release digestive enzymes into the intestines to process nutrients.
Key point: These glands work locally; their secretions don't travel far!
2. Endocrine Glands (Mid and Right Side)
These are your body's "hormone messengers"! Instead of ducts, they release hormones directly into the bloodstream. These hormones then travel throughout your body to regulate key functions: metabolism, hunger, energy, sleep, mood, and yes, weight.
Example: Your pancreas (an endocrine gland) makes insulin, which helps your body use sugar for energy. Your thyroid gland releases hormones that control your metabolic rate (how quickly/slowly your body burns calories).
Endocrine System: Your Body's "Command Center" (right side)
The big circle in the middle? That's your hypothalamus and pituitary gland, the "master regulators" of the endocrine system. They send signals to glands throughout your body:
Thyroid gland: Controls metabolism (slow thyroid = slow calorie consumption).
Pancreas: Manages blood sugar (key to avoiding cravings and fat storage).
Adrenal glands: Releases stress hormones (like cortisol; high cortisol can lead to weight gain).
Reproductive glands (ovaries/testosterone): Influences hormonal balance (estrogen/testosterone imbalances here can affect weight).
Why This Matters to Your Health (and Weight!)
Your endocrine system is like a symphony, and all the glands need to be in tune. If one gland shuts down, it can throw everything off:
Thyroid problems: An overactive thyroid (slowed thyroid function) slows metabolism, making weight gain more likely.
Insulin resistance: If your pancreas has trouble making or using insulin, blood sugar spikes and crashes lead to cravings, fat storage, and obesity.
Cortisol overload: Chronic stress floods your body with cortisol, which can increase appetite (especially for carbs!) and store fat around your belly.
How We Address This in Weight Management
As a doctor, I don't just tell you to "eat less, move more." We take a deep dive into your endocrine health:

Blood: Checks thyroid hormone, insulin, cortisol, and other markers to see if your glands are out of balance.

Personalized Plan: If your thyroid is sluggish, we may treat it. If insulin resistance is an issue, we adjust diet/exercise to improve blood sugar control.

Stress Management: Lowering cortisol (through sleep, meditation, etc.) can help reset hormonal signals that drive overeating.

Your weight isn't just about willpower, it's your body's hormonal "dialogue." If you've been struggling to lose weight, don't blame yourself! Your endocrine system may need some adjustment.

08/01/2025

Discussion Topic at the MHRA Conference: Enhancing Consumer Confidence through Rigorous Regulatory Standards
At the upcoming MHRA conference, I will be discussing the crucial role that regulatory standards play in ensuring the safety, effectiveness, and quality of products reaching the market. The MHRA’s rigorous approval processes not only protect consumers but also provide a platform for innovation, helping manufacturers develop new and improved products that adhere to the highest standards of safety.
One of the key points of my discussion will focus on the ongoing advancements in MHRA regulations and how they address emerging health concerns, especially in sectors like medical devices, pharmaceuticals, and cosmetics. I will also explore how these standards are evolving to meet the demands of a rapidly changing industry, ensuring that consumer confidence is continually strengthened.
By fostering open communication between regulatory authorities, manufacturers, and consumers, we can work towards a future where safe and effective products are consistently available, meeting the diverse needs of the public. The MHRA’s role is pivotal in balancing safety with innovation, ensuring that the public health is always a top priority.

08/01/2025

In clinical studies, users of 𝑆𝑇𝐷𝐸𝐼® 𝐺𝐿𝑃-1 𝑊𝑒𝑖𝑔ℎ𝑡 𝐿𝑜𝑠𝑠 𝑂𝑟𝑎𝑙 𝑆𝑜𝑙𝑢𝑡𝑖𝑜𝑛 have experienced impressive results, with some losing as much as 2-3 pounds of stubborn fat in just one week. Just one vial (0.7 ml) per day targets the burning of visceral and abdominal fat, helping to promote a leaner body without the need for strenuous exercise.

08/01/2025

The root cause of obesity lies in hormonal imbalances and metabolic dysfunction. A sluggish thyroid reduces fat-burning efficiency, while chronic stress elevates cortisol levels, leading to excess abdominal fat. Insulin resistance causes excess sugar to be stored as fat, and poor lymphatic circulation results in toxin and fluid retention, exacerbating bloating and fat accumulation. Additionally, impaired leptin regulation in the liver disrupts satiety signals, driving overeating and creating a vicious cycle. Modern lifestyle factors—high-sugar, high-fat diets, sleep deprivation, and lack of physical activity—further slow metabolism, making fat even harder to burn. Over time, obesity doesn’t just affect appearance; it also increases the risk of serious health issues, making early intervention crucial.

08/01/2025

𝐒𝐓𝐃𝐄𝐈® 𝐆𝐋𝐏-𝟏 𝐖𝐞𝐢𝐠𝐡𝐭 𝐋𝐨𝐬𝐬 𝐎𝐫𝐚𝐥 𝐒𝐨𝐥𝐮𝐭𝐢𝐨𝐧, developed by a team of over 30 experts at the Mayo Clinic’s Department of Metabolic Medicine over 20 years of research, combines Meglutide with potent herbal ingredients to boost metabolism, accelerate fat burning, and support digestive and lymphatic health. MHRA-approved for safety and efficacy, this Oral Liquid offers a science-backed solution for weight loss and overall well-being.

Gary Kase Tate

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