Reports MDPI

01/10/2025

🚨 Latest Publication!

Granulomatous Reactions Following the Injection of Multiple Aesthetic Microimplants: A Complication Associated with Excessive Filler Exposure in a Predisposed Patient
Carmen Rodríguez-Cerdeira & Marjorie Garcerant Tafur | Reports 2025, 8(4), 194
🔗 Read here

https://brnw.ch/21wWggj
A rare case of delayed granulomatous reactions after multiple dermal filler injections is reported. The study emphasizes the importance of pre-procedural immune assessment and shows that conservative, individualized treatment can resolve complications safely without systemic therapy.

29/09/2025

💊 Combined Naltrexone–Bupropion Therapy for Co***ne Use & Obesity

Can a dual therapy tackle both co***ne cravings and weight gain? This case report explores promising results in a 35-year-old patient.

🔗 Read more: https://brnw.ch/21wWbpq

Background and Clinical Significance: Co***ne use disorder (CUD) is characterized by recurrent, cue-triggered and intrusive urges to use co***ne (craving), compulsive drug-seeking despite adverse consequences, and impaired control over intake, often co-occurring with excess weight and hedonic overea...

26/09/2025

📰 Latest Publication in Reports

“Atypical Presentation of Papillon–Lefèvre Syndrome: A Case of Isolated Cutaneous Manifestations Without Dental Involvement”
by Mishari Alrubaiaan, Mansour Almutairi, and Waleed Alajroush

📌 This case report highlights a genetically confirmed instance of Papillon–Lefèvre syndrome (PLS) in a 6-year-old patient presenting with skin manifestations and kidney involvement—but without the typical dental symptoms. The findings underscore the phenotypic variability of PLS.

📄 Read the full article: https://brnw.ch/21wW7U1

Background and Clinical Significance: Papillon–Lefèvre syndrome (PLS) is an autosomal recessive genetic skin disorder. Genetic studies have demonstrated that mutations in the Cathepsin-C (CTSC) gene, mapped to chromosome 11q14.1–q14.3, are responsible for the pathogenesis of PLS. The hallmark c...

19/09/2025

🦴 New in Reports: Rare coexistence of Paget’s disease of bone & normocalcemic primary hyperparathyroidism in an osteoporotic male with fractures.

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Background and clinical significance: Paget’s disease of bone involves anomalies of the bone metabolism; however, the presence of tumor-derivate abnormal parathyroid hormone (PTH) levels does not represent one of these disturbances. To our best knowledge, the association with normocalcemic variant...

15/09/2025

🩺 Latest Publication – Minimally Invasive Guidewire Retrieval

Retained Intrarenal Guidewire Fragment After Endourological Stone Surgery: Antegrade Percutaneous Snare Retrieval and Literature Review
by Timoleon Giannakas et al.
📖 Reports (2025)
👉 https://brnw.ch/21wVLGM

This study highlights a rare complication in endourological stone surgery: a retained intrarenal guidewire fragment. Using a minimally invasive antegrade percutaneous snare, the fragment was safely removed, resolving infection and obstruction. The review summarizes all reported intrarenal cases to date and emphasizes prevention and early detection to avoid such “never events.”

Background and Clinical Significance: Retained intrarenal foreign bodies are rare adverse events after endourological stone surgery. Guidewire fracture or detachment is uncommon and can trigger infection, obstruction, or encrustation if unrecognized. We report antegrade percutaneous snare retrieval ...

12/09/2025

🆕 New in

💊 Personalizing Pain Relief
shows promise for post-amputation pain, but response varies. could guide dosing for better, personalized outcomes.

Read more 👇
🔗 https://brnw.ch/21wVHOR

Context and objective: Post-amputation pain (PAP) is an umbrella term that includes residual limb pain (RLP) and phantom limb pain (PLP), posing a significant challenge to recovery and quality of life after limb loss. Ketamine, an N-methyl-D-aspartate (NMDA) receptor antagonist, has gained interest ...

10/09/2025

🩺 Kidney Stones in Kids? Meet Cystinuria!

Two pediatric cases reveal how genetic cystinuria can be managed with hydration, diet, and cystine-binding meds. One child used tiopronin, the other D-penicillamine—both saw fewer stones and better outcomes!

A small tweak in treatment can make a big difference. 💊💧

📖 Check it out: https://brnw.ch/21wVDmm

10/09/2025

🔊 High-Risk Pregnancy in Single Ventricle Physiology

A 38-year-old woman with Fontan physiology and acquired von Willebrand syndrome faced a complex pregnancy with preterm premature rupture of membranes, abnormal placental vasculature, and prior obstetric complications.

Through early activation of a multidisciplinary cardio-obstetrics team and tailored planning, she successfully delivered at 24 weeks via cesarean, with postpartum hemorrhage managed effectively.

This case highlights how multidisciplinary coordination and individualized birth plans are critical for optimal maternal–fetal outcomes in complex congenital heart disease.

🔗 Read the full case report:

Background and Clinical Significance: Left ventricular hypoplasia is often repaired surgically in sequence to a Fontan circulation, which is a physiologic state that presents unique challenges during pregnancy. Although women with Fontan physiology can achieve successful pregnancy outcomes, they rem...

08/09/2025

💓 Silent Threat, Sudden Crisis

A 55-year-old man with previously normal heart exams suddenly developed acute pulmonary edema—all because of a giant left atrial myxoma!

Thanks to fast echocardiography and emergency surgery, he made a full recovery. This case is a stark reminder: even silent cardiac tumors can turn life-threatening in an instant.

❓ Could earlier detection save more lives?

Read the full story 👇
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Background and Clinical Significance: Cardiac myxomas, though typically benign and asymptomatic, can rarely present with acute cardiovascular compromise. We report a case of a left atrial myxoma presenting as acute pulmonary edema in a patient with prior normal cardiac imaging. Case Presentation: A ...

05/09/2025

🌟 New in Reports

📖 A Rare Case of Posteriorly Migrated Sequestered Lumbar Disc Herniation Through the Interlaminar Space

🧑🏻‍🔬 By Merih Can Yilmaz and Keramettin Aydin

🔗 https://brnw.ch/21wVuxn

This rare case highlights a posteriorly migrated lumbar disc herniation not detected by imaging but successfully treated surgically, emphasizing the need for clinical vigilance.

Background and Clinical Significance: Posteriorly migrated lumbar disc herniation [PMLDH] is a rare entity that may present with atypical clinical and radiological features, often mimicking other spinal pathologies. Migration of sequestered fragments through the interlaminar space is exceptionally u...

03/09/2025

🔥 New in Reports

🧬 Prader–Willi Syndrome (PWS) doesn’t just affect appetite and growth — it can also disrupt how the body regulates temperature.

This study of 44 youths with PWS found:
❄️ Hypothermia in 8 cases
🌡️ Hyperthermia in 2 cases
↔️ Both in 2 cases

👉 That’s 1 in 5 children with temperature dysregulation.
⚠️ Strong link with sleep apnea, but not explained by body composition or motor traits.

These findings shine light on an under-recognized clinical issue in PWS and call for deeper research into the physiological mechanisms at play.

📖 Read more:

Background: Prader–Willi Syndrome (PWS) is a genetic neurodevelopmental disorder caused by an alteration of the paternal chromosome 15q11-q13. Youth with PWS present hyperphagia, increased fat/decreased muscle mass, hypotonia, and decreased metabolic rate with risk of obesity. Thermoregulation pro...

02/09/2025

🌟 Meet MDPI at EVER 2025! 🌟

Reports is excited to share that MDPI will be attending the 28th EVER Congress (EVER 2025) as an exhibitor! Join us in Florence, Italy, from 9–11 October 2025 to connect with researchers, share ideas, and explore the latest advances in ophthalmology and visual sciences.

EVER is Europe’s leading ophthalmological research association, bridging basic science and clinical eye research across areas such as retina, glaucoma, cornea, ocular surface, oncology, pediatric ophthalmology, neuro-ophthalmology, and lens disorders. This annual congress gathers top researchers and clinicians from around the world—don’t miss it!

👉 Visit our booth, meet our team, and learn how Reports can support your research!

More info here: https://brnw.ch/21wVoln