Reports MDPI

11/12/2025

🩺 Extremely Rare Case Alert!

A 64-year-old man diagnosed with non-syndromic ganglioneuromatosis of the gallbladder—one of the very few adult cases reported. Highlights the importance of histology in rare gallbladder conditions.

🔗 https://brnw.ch/21wYhiT

Background and Clinical Significance: Ganglioneuromatosis is a benign proliferation of mature ganglion cells, Schwann cells, and nerve fibers within the enteric or autonomic nervous system. According to the WHO classification, it encompasses a spectrum range from solitary ganglioneuroma to ganglione...

10/12/2025

🧐 Ever heard of ganglioneuromatosis of the gallbladder?

A recently published case report highlights an extremely rare, non-syndromic occurrence of this benign nerve cell proliferation in a 64-year-old patient — adding a unique entry to medical literature!

Key points:

Ganglioneuromatosis usually affects the colon or small bowel and is often linked to hereditary syndromes like NF1, MEN2B, or Cowden.

This case is non-syndromic, meaning no associated genetic condition was found.

Histology revealed mature ganglion cells and hypertrophic nerve fibers in the gallbladder, confirmed via immunohistochemistry.

This report is a valuable reference for clinicians and pathologists encountering unusual gallbladder lesions.

📖 Read the full article here: https://brnw.ch/21wYf5E

Background and Clinical Significance: Ganglioneuromatosis is a benign proliferation of mature ganglion cells, Schwann cells, and nerve fibers within the enteric or autonomic nervous system. According to the WHO classification, it encompasses a spectrum range from solitary ganglioneuroma to ganglione...

05/12/2025

📄 New in Reports!
A case of congenital duodenal diaphragm in a toddler presenting with chronic vomiting and poor weight gain.
Diagnosis confirmed by imaging + gastroscopy; treated surgically with great outcome.

👉 Read the full case report

Background and Clinical Significanc: Congenital duodenal diaphragm (CDD) is a rare congenital condition causing partial or complete obstruction of the duodenum, most frequently located in the second part of the duodenum. It is a rare but important cause of intestinal obstruction in infants and young...

04/12/2025

We had the great opportunity at the Joint International Tropical Medicine Meeting 2025 to meet with Prof. Dr. Toshio Hattori, our Editor-in-Chief. It was inspiring to discuss the latest developments in tropical medicine and future directions for the journal! 🌍🧬

03/12/2025

🌴 Exciting times at the Joint International Tropical Medicine Meeting 2025!

The Journal Reports (MDPI) team is on-site at Booth S8 – come visit us to learn about our latest publications, special issues, and opportunities for authors in tropical medicine research. 🧬✨

Looking forward to connecting with researchers, sharing insights, and discussing the latest trends in tropical medicine.

03/12/2025

📢 Latest Publication Alert
A new case report titled “Creutzfeldt–Jakob Disease Mimicking Transient Brain Ischemia in a Patient with a Mitral Valve Prosthesis” has just been published in Reports.
Authored by Goda Barauskienė, Medeinė Laurikaitytė, Daiva Emilija Rekienė, Saulius Sadauskas, Albinas Naudžiūnas, and Edita Mašanauskienė, this case highlights the diagnostic complexity of Creutzfeldt–Jakob disease (CJD) when early symptoms overlap with transient ischemic events.
The report describes a male patient with a mitral valve mechanical prosthesis whose rapidly progressive cognitive decline initially suggested cardiovascular or ischemic causes. Only through comprehensive neuroimaging was probable CJD identified—underscoring the importance of multidisciplinary evaluation in challenging neurological cases.
➡️ Read the full report to explore this unique presentation and its diagnostic implications.

Background and Objectives: Creutzfeldt–Jakob disease (CJD) is a rare and fatal neurodegenerative disorder caused by prion protein misfolding. The disease poses significant diagnostic challenges, particularly when its initial symptoms mimic other conditions, such as transient ischemic attacks. Earl...

01/12/2025

📢 Latest Publication Alert

A new case report titled “Bilateral Sterile Intraocular Inflammation Following Intravitreal Aflibercept 8 mg Injections” by Ram Cohen, Tomer Kerman, and Omer Trivizki has just been published in Reports.

The authors describe an 89-year-old patient with neovascular age-related macular degeneration who developed bilateral sterile intraocular inflammation shortly after receiving high-dose aflibercept (Eylea HD).
Thanks to prompt recognition and intensive topical treatment, the patient achieved full recovery of vision within four days.

This report underscores the importance of clinical awareness regarding potential inflammatory reactions to aflibercept 8 mg—even in patients who previously tolerated standard doses.

➡️ Read the full case report to learn more about the presentation, differential diagnosis, and management.

Purpose: To report a case of bilateral sterile intraocular inflammation following intravitreal aflibercept 8 mg (Eylea HD) injections. Observation: An 89-year-old woman with bilateral neovascular age-related macular degeneration (nAMD) developed blurred vision and mild ocular pain in both eyes four ...

27/11/2025

🩺 Rare Case Highlight: Paclitaxel-Induced Collagenous Colitis in Male Breast Cancer

A recent case report details a 71-year-old patient with metastatic breast cancer who developed acute collagenous colitis after paclitaxel treatment, presenting with severe watery diarrhea. Colonoscopy and histopathology confirmed the diagnosis. Importantly, stopping paclitaxel led to full recovery.

This report underscores the need for heightened awareness of rare chemotherapy-induced adverse events and the importance of timely intervention for optimal patient outcomes.

Read the full report here: https://brnw.ch/21wXSRn

Background and Clinical Significance: Collagenous colitis is an uncommon form of microscopic colitis characterized by chronic watery diarrhea and thickening of the subepithelial collagen layer. While various medications have been implicated in its pathogenesis, paclitaxel-associated collagenous coli...

25/11/2025

💊 Rare but important! A 71-year-old male with metastatic breast cancer developed paclitaxel-induced collagenous colitis, causing severe diarrhea. Early recognition and stopping the drug led to full recovery.

📖 Read the case report: https://brnw.ch/21wXObg

Background and Clinical Significance: Collagenous colitis is an uncommon form of microscopic colitis characterized by chronic watery diarrhea and thickening of the subepithelial collagen layer. While various medications have been implicated in its pathogenesis, paclitaxel-associated collagenous coli...

21/11/2025

📢 New Case Report Highlight

Check out the paper:
“Gossypiboma, a Rare Cause of Abdominal Pain: A Case Report”

This study describes a rare case of retained surgical gauze causing abdominal pain, emphasizing the importance of careful surgical counts and awareness for early diagnosis and treatment.

📄 Read more: https://brnw.ch/21wXHJq

Gossypiboma is a retained surgical item, most commonly gauze or sponge, inadvertently left inside a patient’s body after surgery. Although preventable, it can cause severe complications and is often underreported due to medicolegal concerns. We present a case of a 61-year-old woman who experienced...

20/11/2025

🆕 Published in Reports!

Left Ventricular to Right Atrial Shunt in a Preterm Infant: A Case Report by Aimann Surak.
A rare diagnosis identified using targeted neonatal echo (TnECHO)—showing its growing value in assessing hemodynamic instability in very preterm infants. ❤️‍🩹
🔗 https://brnw.ch/21wXEsY

Background and Clinical Significance: Premature infants are at high risk of life-threatening complications due to the immaturity of multiple organ systems, and close monitoring in neonatal intensive care units is indispensable for their stabilization, survival, and morbidities. Despite major advance...

18/11/2025

New Case Report: Gunshot Chest Wound Managed with Cardiopulmonary Bypass 🫀🔪

A rare and complex case highlights successful management of a gunshot wound to the chest using emergency cardiopulmonary bypass (CPB). A 53-year-old patient in hemorrhagic shock underwent pneumorrhaphy under CPB, resulting in survival and full recovery.

This case demonstrates the critical role of interdisciplinary teamwork, clinical expertise, and advanced surgical equipment in life-saving procedures.

Read the full study: https://brnw.ch/21wXAik

Background and clinical significance. Penetrating cardiothoracic wounds require prompt treatment in order to decrease mortality and morbidity. Surgical therapy, aimed at bleeding control and removal of damaged tissue, varies widely from the direct suture of parenchymal lacerations to pneumonectomy, ...