http://apc.aast.edu/ojs/index.php/AMPDR/

Advances in Medical, Pharmaceutical and Dental Research Journal, 9 Abou Qear, Abu Qir Al Gharbeyah, Montaza 2, Alexandria Governorate, Alexandria (2025)

17/06/2025

Advances in Medical, Pharmaceutical and Dental Research Journal
Vol 4, No 1 (2024)
https://apc.aast.edu/.../inde.../AMPDR/issue/view/80/showToc

Experimental and Applied Dental research
Chemical constituents analysis of blue vitriol, brimstone and black stone using X-ray fluorescence technology and GC-MS: a quest for novel antifungals
Onyekachukwu Izuchukwu Udemezue, Onyekachi Ijeoma Udemezue, Evangeline Chinyere Udenweze, Chijioke Obinna Ezenwelu, Euphemia Afoma Ikegwuonu
DOI: https://dx.doi.org/10.21622/AMPDR.2024.04.2.857

Abstract

New drugs especially antifungals are continually required by healthcare systems to address serious public health challenges such as resistance, toxicity, cost and scarcity. This research aimed at analyzing the chemical constituents of blue vitriol, brimstone and black stone using x-ray fluorescence technology and gas chromatography-mass spectroscopy (GC-MS); a quest for novel antifungal agents. The test isolates were obtained from high vaginal swab samples of patients attending a University Teaching Hospital in Anambra State, Nigeria. The isolates were identified based on their morphological, physiological and molecular characteristics. The minimal inhibitory concentration (MIC) and minimal fungicidal concentration (MFC) were determined using the broth dilution method. The inorganic and organic constituents of the natural compounds were determined using x-ray fluorescence technology and GC-MS respectively. The isolates include Candida albicans, C. tropicalis, C. glabrata and C. parapsilosis. The MIC and MFC of blue vitriol against the isolates ranges from 12.50mg/ml – 100mg/ml, brimstone (50mg/ml – 200mg/ml), black stone (200mg/ml) and ketoconazole(positive control):12.50mg/ml - 50mg/ml. The inorganic components found in blue vitriol include oxides of copper (43.7%), sulphur (29.4%), aluminium (1.2%); while the heavy metals arsenic, lead and nickel (all

02/06/2025

Advances in Medical, Pharmaceutical and Dental Research Journal
Vol 4, No 1 (2024)
https://apc.aast.edu/.../inde.../AMPDR/issue/view/80/showToc

Experimental and Applied Dental research
Integrative dental management of complex patients: a comprehensive care case report
Alaa Mohamed Eltaweel, Reem A. Hassanin
DOI: https://dx.doi.org/10.21622/AMPDR.2024.04.2.1003

Abstract

This Comprehensive Care Case (CCC) report represented a detailed diagnosis and treatment plan to manage a complex dental patient who came to the outdoor dental clinic of the faculty of dentistry, Arab Academy for Science, Technology, and Maritime Transport in Alamein (AAST). Fatma, a 32-year-old female patient, had been presented with continuous dental pain, improper dental functions, and an aesthetic problem. The staff team, comprising specialists in different dental departments supervised this case with the undergraduate student. Together, they have tailored a treatment plan that integrated cumulative phases. Outcomes were assessed through both radiographical and clinical metrics as well as patient-reported outcomes, demonstrating significant improvements in pain relief, dental functions, and aesthetics. This case illustrated the effectiveness of collaborative care models in addressing the complex clinical challenges with an optimum treatment plan that meets the patient's needs and satisfaction.

It also highlighted the importance of departmental cooperation, social communication, and the role of the university in community service. Our findings contribute to the growing body of evidence supporting comprehensive care strategies for complex patients, suggesting implications for clinical practice and future research.

18/05/2025

Advances in Medical, Pharmaceutical and Dental Research Journal
Vol 4, No 1 (2024)
https://apc.aast.edu/.../inde.../AMPDR/issue/view/80/showToc

Experimental and Applied Dental research
A full mouth rehabilitation restoring function and aesthetics (case report)
Muhammad R. Morgan, Ahmed W. Belal, Raneem M. Gamal, Eman M. Soliman
DOI: https://dx.doi.org/10.21622/AMPDR.2024.04.2.979

Abstract

Background: This study presents a clinical case report of a middle-aged patient with pain in the posterior mandibular first molar, especially while eating, multiple edentulous spaces, and bleeding upon brushing. Periodontal therapy, non-surgical extraction, endodontic therapy, restorative treatment, and prosthetic treatment were all included in the multidisciplinary procedure.

Purpose: Restoring appropriate occlusion and enhancing appearance were the goals of the treatment plan.

Methodology: The patient's treatment approach was commenced by clinical and radiographical examination, including panoramic X-ray and multiple periapical X-rays, followed by diagnosis, phases of treatment, the insertion of monolithic zirconia full coverage restorations, and porcelain fused to metal fixed partial denture.

Conclusion: There was an improvement concerning esthetics and function. An integrated treatment strategy is crucial for achieving optimal outcomes in full-mouth rehabilitation. Appropriate treatment planning requires careful assessment of the etiology, history, and factors pertaining to the oral health condition.

15/05/2025

Advances in Medical, Pharmaceutical and Dental Research Journal
Vol 4, No 1 (2024)
https://apc.aast.edu/.../inde.../AMPDR/issue/view/80/showToc

Experimental and Applied Dental research
Complete dental rehabilitation utilizing removable partial dentures and monolithic zirconia crowns (case report)
Hagar Ibrahim, Marwan Aggag
https://dx.doi.org/10.21622/AMPDR.2024.04.2.965

Abstract

Bilateral edentulous areas are a common clinical presentation, and in most of those cases, implant repair may not be possible. As a result, the conventional metallic partial denture is still in use. As our awareness of appearance has grown in our daily life , esthetics became a crucial component of dentistry. consequently, patients ask for aesthetic restorations that also maintain functionality. Zirconia is a widely used material for both functional and aesthetic demands. It has been demonstrated that zirconia can endure occlusal and functional stresses without neglecting the aesthetic appearance that is expected of a tooth-colored restoration. which is why using it as surveyed crowns to support partial dentures is optimal.

Objectives: The goal of this case study is to demonstrate a method for restoring a partially edentulous patient through the use of a metallic partial denture held up by surveyed zirconia crowns using CAD-CAM technology.

29/04/2025

Advances in Medical, Pharmaceutical and Dental Research Journal
Vol 4, No 1 (2024)
https://apc.aast.edu/.../inde.../AMPDR/issue/view/80/showToc

Experimental and Applied Dental research
Monolithic zirconia crowns and fixed partial denture in anterior and posterior regions as a prosthetic solutions (case report)
Ahmed Islam Abourayan, Marwan Aggag
DOI: https://dx.doi.org/10.21622/AMPDR.2024.04.2.964

Abstract

The increase in patient’s demand for an esthetic natural like and a strong functional restoration now days, using of all-ceramic zirconia fixed partial denture for rehabilitation of missing posterior teeth has been increasing in daily dental practice, Although dental implants are the treatment of choice in most of our cases today, but it’s not always executable for all patients due to many reasons such as, chronic smoking, alcoholism, uncontrolled diabetes, and most importantly poor oral hygiene. Monolithic, multilayer zirconia gave the desired mechanical strength that can withstand high masticatory forces, without having a negative effect on its esthetic appearance, which makes it the material of choice in our case.

14/04/2025

Advances in Medical, Pharmaceutical and Dental Research Journal
Vol 4, No 1 (2024)
https://apc.aast.edu/.../inde.../AMPDR/issue/view/80/showToc

Experimental and Applied Dental research
Interdisciplinary approach to unilateral missing maxillary lateral incisor with preparation modification (case report)
Mohamed Shaalan, Ibrahim Allam, Marwan Aggag
DOI: https://dx.doi.org/10.21622/AMPDR.2024.04.2.963

Abstract

Background: In many clinical cases where one or both maxillary lateral incisors are absent, orthodontic treatment with space opening or closure using canine and premolar replacement has led to improved periodontal health and high patient satisfaction however with long treatment period. Preparation modification of the maxillary canine can simulate lateral incisor and first premolar can mimic the canine for appearance. Zirconia crowns have shown they can withstand occlusal and functional stresses while maintaining the required aesthetic appearance.

Objectives: This case highlighted management of unilateral missing maxillary lateral incisor with only preparation modification using digital smile design and CAD- CAM technology.

08/04/2025

Advances in Medical, Pharmaceutical and Dental Research Journal
Vol 4, No 1 (2024)
https://apc.aast.edu/.../inde.../AMPDR/issue/view/80/showToc

Experimental and Applied Dental research
Oral health findings and comprehensive management of a patient with hypotonic cerebral palsy- a case report with a two-year follow-up
Amol Suresh Patil, Aditi Mhatre, Sayali Katkar, Shreya Shah, Samhita Bahutule, Madhuri Patil
DOI: https://dx.doi.org/10.21622/AMPDR.2024.04.2.855

Abstract

Background- Cerebral palsy is a group of disorders that affect the movement and muscle tone or posture caused by a non-progressive abnormality of the immature brain that originates during the prenatal period/first few years of life. The dentist is a crucial element of the interdisciplinary healthcare team that treats this special group since cerebral palsy patients frequently have oral manifestations.

Case report- This case report presents a 14-year-old male with hypotonic cerebral palsy and a description and importance of a comprehensive dental approach. On oral examination, the patient presented poor oral hygiene, plaque accumulation, several carious teeth in the upper and lower arch, and root stumps. A comprehensive dental treatment was planned and performed accordingly.

Conclusion: This case report underscores the vital role of comprehensive, structured dental interventions in enhancing the oral health-related quality of life for children with cerebral palsy. It's imperative to raise awareness about the significance of well-planned oral health strategies in caring for individuals with cerebral palsy, thereby ensuring a fulfilling and healthier life for these patients and their caregivers.

27/03/2025

Call for Papers: Advances in Medical, Pharmaceutical and Dental Research (AMPDR)
Advances in Medical, Pharmaceutical and Dental Research (AMPDR)invites submissions for our upcoming issue , AMPDR is a peer-reviewed, open access, interdisciplinary journal, with two issues yearly. scientific journal dedicated to the dissemination of innovative research works spanning the entire spectrum of medicine, pharmacy and dentistry. The journal has three main sections, namely: Medical and Clinical Research, Advanced Research in Pharmaceutical Sciences and Experimental , and Applied Dental Research. The journal also encourages the publication of multidisciplinary researches spanning pharmaceutical, medical, biomedical engineering, biotechnology and artificial intelligence fields.

Submission Link: https://apc.aast.edu/ojs/index.php/AMPDR/user/register

16/03/2025

Advances in Medical, Pharmaceutical and Dental Research Journal
Vol 4, No 1 (2024)
https://apc.aast.edu/.../inde.../AMPDR/issue/view/80/showToc

Experimental and Applied Dental research
Comparative evaluation of bond strength of essential oil modified composite resin to enamel (In-Vitro)
Elian Basha, Monzer Haddad
DOI: https://dx.doi.org/10.21622/AMPDR.2024.04.2.798

Abstract

Objectives: The aim is to evaluate the bond strength of essential oil-modified composite resin to enamel.

Materials and Methods: 84 molars were embedded in acrylic molds with the buccal surfaces facing upwards, then they were divided into three groups according to the type of essential oil used (n=28): Group 1: Cinnamon oil, Group 2: Thyme oil, Group 3: Clove oil. Each group was then divided into four subgroups according to the concentration of essential oil used to modify the Flowable Composite Resin (CR) (n=7): Subgroup 1 : negative control, Subgroup 2: concentration 1µL/2g CR, Subgroup 3 : concentration 2µL/2g CR, Subgroup 4 : concentration 5µL/2g CR. plastic molds were fixed and the flowable composite was applied and cured. Finally, the shear bond strength test was conducted.

Results: Mean SBS values of Cinnamon group was significantly higher than the control subgroup (P = 0.001) but this did not apply to Thyme (P = 0.189) and Clove Oil (P = 0.386) groups. The source of the significance of the SBS values in the CInnamon oil group was between the control subgroup and every experimental one.

Conclusion: Mean SBS values of Cinnamon oil modified composite resin were significantly higher than the control group. Mean SBS values of Thyme oil and Clove oil modified composite resins were not significantly higher than the control group.

10/03/2025

Advances in Medical, Pharmaceutical and Dental Research Journal
Vol 4, No 1 (2024)
https://apc.aast.edu/.../inde.../AMPDR/issue/view/80/showToc

Experimental and Applied Dental research
Dental caries and traumatic dental injury among orphans and children in orphanage homes
Obehi O. Osadolor, Aisosa J. Osadolor
DOI: https://dx.doi.org/10.21622/AMPDR.2024.04.2.926

Abstract

Background: Dental caries is a dynamic oral disease that can affect all socioeconomic status. Traumatic dental injuries (TDIs) are injuries to the teeth and surrounding tissues as a result of impact. An orphan is a child who has lost one or both parents, and Africa has countries with orphans and children living in orphanage homes . Method: An electronic literature search in PubMed, Science Direct and African journals online was done in June , 2024 using the Population, Concept and Context framework.Search terms and keywords were combined by Boolean operators. Two independent investigators screened titles and abstracts of publications on dental caries and traumatic dental injuries among orphans and children in orphanage homes. The inclusion criteria was original (primary) research articles on dental caries and traumatic dental injuries among orphans and children in orphanage homes, while review articles, systematic reviews, viewpoints, books, thesis, editorials, dissertations, perspectives, and news were among articles excluded during screening.Results: Two articles with accessible full text were included for review. The studies were carried out in Egypt and Nigeria and it was a case control study and cross sectional study respectively. Conclusion: Dental caries and traumatic dental injuries are significant public health problem that can affect the quality of life of orphans and children in orphanage homes. Improving awareness on preventive measures for traumatic dental injuries and dental caries among the caregivers in orphanage homes and visit to dental clinic by orphans and children in orphanage homes for clinical assessment and management is recommended.

03/03/2025

Advances in Medical, Pharmaceutical and Dental Research Journal
Vol 4, No 1 (2024)
https://apc.aast.edu/.../inde.../AMPDR/issue/view/80/showToc

Medical and Clinical Research
Designing strategies to reach the maximum number of women for comprehensive knowledge of human immunodeficiency virus (HIV)
Jaimini Sarkar, Chiradeep Sarkar
DOI: https://dx.doi.org/10.21622/AMPDR.2024.04.2.941

Abstract

Background:

Globally women are the major victims of socio-economic and political inequalities. This applies equally to stigma and discrimination related to HIV awareness and treatment. The biggest challenge is not only to reach all HIV-infected people but also to reach the maximum number of people for counseling and testing to avoid future transmission. There is a need to frame cost-effective, rapid, and confidential awareness strategies that will eventually encourage people to test.

Study Design:

Anonymized, publicly available data of the India National Family Health Survey (NFHS-5) and ASHAs per state is collected from the Ministry of Health and Family Welfare, India. Descriptive statistical analysis, linear regression analysis, and Pearson correlation coefficient analysis were done for the data.

Results:

The multiple linear regression equation for women with comprehensive HIV knowledge (%) shows an R square value of 0.2338 for an overall p-value of 0.0123. Pearson correlation indicated that there is a non-significant medium negative relationship between ASHAs per state (%) and women with knowledge of HIV (%) (r = -0 .315, p = 0.061). Whereas, the results of the Pearson correlation indicated that there is a significant medium-positive relationship between the percentage of women with internet access and the percentage of women with comprehensive knowledge of HIV, (r =0 .481, p = 0.003).

Conclusions:

Internet access to women is more beneficial in states where the literacy is high. In areas where internet access and understanding content in English is an issue, community health workers can provide better support to spread awareness.

23/02/2025

Advances in Medical, Pharmaceutical and Dental Research Journal
Vol 4, No 1 (2024)
https://apc.aast.edu/.../inde.../AMPDR/issue/view/80/showToc

Medical and Clinical Research
Full mouth rehabilitation of partially edentulous patient: a case report
Mirna Mohamed Atef, Yara A. Kammoun
DOI: https://dx.doi.org/10.21622/AMPDR.2024.04.2.1017

Abstract

Complete mouth rehabilitation involves restoring oral health for patients with extensive dental issues. This article explores the essential elements of the rehabilitation process, including diagnostic assessment, treatment planning, and the use of restorative and prosthetic techniques. It highlights the importance of a multidisciplinary approach and aims to clarify how integrating various dental disciplines contributes to effective outcomes. The study focuses on providing a comprehensive overview of these methodologies and assessing their effectiveness in meeting functional needs, offering insights into achieving optimal results through coordinated care.

Advances in Medical, Pharmaceutical and Dental Research Journal

17/06/2025

02/06/2025

18/05/2025

15/05/2025

29/04/2025

14/04/2025

08/04/2025

27/03/2025

16/03/2025

10/03/2025

03/03/2025

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