13/05/2025
HISTORY OF GENETICS 13/05/2025
1. Who discovered the role of chromosomes in
heredity?
a. T H Morgan
b. H J Muller
c. Beadle and Tatum
d. Lederberg and Lederberg.
2. Who proposes one gene and one enzyme
concept?
a. T H Morgan
b. H J Muller
c. Beadle and Tatum
d. Lederberg and Lederberg.
3. Who develops a mutation in drosophila by X
ray irradiations?
a. T H Morgan
b. H J Muller
c. Beadle and Tatum
d. Lederberg and Lederberg.
4. Who proposes genetic recombination and
organization of genetic material of bacteria?
a. T H Morgan
b. H J Muller
c. Beadle and Tatum
d. Lederberg
5. ………….. demonstrate in vitro synthesis of
RNA.
a. Ochoa
b. Kornberg
c. Crick.
d. Watson
6. ………………. proposed double helical model
of DNA and significance for information
transfer of DNA in the living material.
a. Crick
b. Watson
c. Wilkins
d. All of these
7. Operon concept given by………..
a. Jacob and Monod
b. Ochoa
c. Kornberg
d. Crick.
8. ……… gives Genetic regulation of enzyme
action.
a. Jacob and Monod
b. Ochoa
c. Kornberg
d. Crick.
9. The significance of DNA for information
transfer in living material is said by………..
a. Crick, Watson, and Wilkins
b. Jacob and Monod
c. T H Morgan
d. H J Muller
10. The discovery of genetic code and its function
in protein synthesis given by
a. H G Khorana and Nirenberg
b. Holley et al
c. Arber, Nathans, and Smith
d. Fredrick Sanger.
11. Who proposes the structure of the RNA
a. H G Khorana and Nirenberg
b. Holley et al
c. Arber, Nathans, and Smith
d. Fredrick Sanger.
12. …………… known as Lady Mendel?
a. Barbara Mc Clintock
b. Sanger
c. Rosalind Franklin
d. Wilkins
13. Who discovered the base sequence of
nucleotides in DNA?
a. Barbara Mc Clintock
b. Sanger
c. Rosalind Franklin
d. Wilkins
14. ………….. proposes the discovery of RNA
acting as the catalytic enzyme.
a. Cech and Altmann,
b. Barbara
c. Sanger
d. Holley et al.
15. Frederic Meischer discovered nucleic acid in
the nucleus of a pus cell and called it ……..
a. nuclein.
b. Nucleic acid
c. DNA
d. RNA
16. Who coined the term Nucleic acid?
a. Altmann.
b. Mendels
c. Kornberg.
d. Wilkins.
17. Which of the following is correctly matched?
a. Muller- One Gean One enzyme
concept
b. Ochoa and Kornberg- synthesis of
RNA
c. Morgan- operon concept
d. Crick, Watson, and Wilkins- double
helical DNA
