Ijpsr Journal (2025)

06/11/2025

Nuclear Medicine: The Power of Precision in Modern Healthcare

Have you ever wondered how doctors can see deep inside the body to diagnose diseases before symptoms appear? Welcome to the world of Nuclear Medicine, a groundbreaking branch of medical science that goes beyond structure to reveal function, metabolism, and molecular activity.

From early cancer detection to targeted treatment of thyroid and prostate disorders, nuclear medicine leverages tiny amounts of radiopharmaceuticals to diagnose and treat a wide range of diseases with unmatched accuracy. With cutting-edge technologies like PET/CT and SPECT/CT, clinicians can visualize complex biological processes in real time, often leading to faster, more effective care.

🧪 Key Highlights:

▪️Functional imaging that reveals molecular-level changes
▪️PET & SPECT scans guiding critical decisions in oncology, cardiology, and neurology
▪️Therapeutic isotopes like Iodine-131 and Lutetium-177 for precise cancer treatment
▪️Emerging role in personalized medicine and targeted therapies

As we step into an era of precision healthcare, nuclear medicine stands at the forefront, transforming diagnosis and therapy through innovation and insight.

The journey of nuclear medicine is just beginning. With rapid advancements and expanding applications, it’s not just about treating disease. It is about understanding it at the deepest level and empowering patients with tailored, effective care.

Let’s continue to explore its potential and make healthcare smarter, safer, and stronger.

🔗 https://ijpsr.com/bft-article/nuclear-medicine-a-comprehensive-review/?view=fulltext

Share your thoughts or tag someone working in NUCLEAR MEDICINE.

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Elevate your professional journey with Society of Pharmaceutical Sciences and Research (SPSR) — become a member today: https://spsrpharma.org

01/11/2025

🌿 Green Nanotechnology: Plant-Powered Pathway to Bismuth Nanoparticles (BiNPs)

In the era of sustainable science, green synthesis of Bismuth nanoparticles (BiNPs) using plant extracts is revolutionizing nanomaterial fabrication, merging biotechnology with eco-conscious innovation.

Unlike conventional methods that rely on toxic chemicals and energy-intensive steps, this approach harnesses nature’s own reducing agents, flavonoids, phenolics, terpenoids, and alkaloids for clean, efficient, and biocompatible nanoparticle synthesis.

🔬 Key Highlights:

🌱 Eco-friendly approach: Eliminates hazardous reagents, aligning with green chemistry principles.

⚗️ Natural reducing/stabilizing agents: Plant metabolites act as multifunctional biofactories.

💠 Controlled synthesis: Parameters like pH, temperature & time tune particle morphology and activity.

🧫 Broad applications: From antibacterial and anticancer therapies to bioimaging and pollutant degradation.

🧩 Characterization tools: UV-Vis, FTIR, XRD, SEM, TEM, and zeta potential reveal nanoscale precision.

However, challenges such as extract variability, mechanistic gaps, and protocol standardization still need focused research for large-scale, reproducible outcomes.

The future of nanomedicine is green, and it’s growing leaf by leaf.

Let’s reimagine sustainable nanotechnology where biology meets bismuth for a cleaner, smarter tomorrow.

🔗 https://ijpsr.com/bft-article/green-nanotechnology-in-focus-plant-mediated-synthesis-and-applications-of-bismuth-nanoparticles/?view=fulltext

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Elevate your professional journey with Society of Pharmaceutical Sciences and Research (SPSR) — become a member today: https://spsrpharma.org

31/10/2025

October FDA Approval:

Lynkuet (elinzanetant) Capsules: The first and only dual 1 & 3 therapy for moderate to severe hot flashes due to .

marks a natural transition in a woman’s life, often accompanied by challenging vasomotor symptoms such as hot flashes and night sweats. For decades, hormone therapy has been the mainstay treatment — but not all women are suitable candidates.

🔬 Mechanism of Action:

Elinzanetant is a dual neurokinin-1 and neurokinin-3 receptor antagonist. It works by modulating thermoregulatory pathways in the — the area responsible for body temperature control. By blocking neurokinin signaling, it helps restore balance in temperature regulation, thereby reducing the frequency and severity of hot flashes.

⚠️ Adverse Effects:

Common side effects may include headache, fatigue, nausea, abdominal discomfort, and sleep disturbances. Most are mild to moderate and transient.

🚫 Contraindications:

▪️ Known hypersensitivity to elinzanetant or its excipients
▪️Severe hepatic impairment
▪️Concurrent use with strong CYP3A4 inducers or inhibitors (may affect drug metabolism)

Lynkuet (elinzanetant) represents a breakthrough in menopausal care, providing effective, hormone-free relief with a mechanism rooted in neuroendocrine science. It empowers women to embrace menopause with renewed comfort, confidence, and balance.

For women ready to embrace the change, Lynkuet delivers a new choice, scientifically grounded, hormone-free, and tailored for today.

➡️ Redefining comfort. Restoring confidence ⬅️

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Elevate your professional journey with Society of Pharmaceutical Sciences and Research (SPSR) — become a member today: https://spsrpharma.org

29/10/2025

Sunlight vs. Science: Which Drying Method Wins for Sauropus androgynus?

Ever wondered how a simple drying method can change the health power of a leafy green?

This latest research dives into just that revealing how processing choices can make or break the nutritional punch of Sauropus androgynus leaves, a superfood packed with vitamins, minerals, and antioxidants.

✅ Key Findings

• Sun drying retained better essential nutrients and antioxidants
• Leaves dried under sunlight showed improved color, taste & acceptability
• All drying methods effectively reduced microbial load
• Hot air oven and freeze-dried leaves showed slightly lower sensory appeal

Sun drying stands out as the most effective and natural technique to preserve the nutritional richness and sensory qualities of Sauropus androgynus leaves offering a cost-efficient and sustainable approach for food processing and herbal-based industries.

This research supports traditional preservation methods while bridging modern scientific insights to enhance functional food development.

If you are passionate about phytopharmaceuticals, nutrition, or sustainable food technology share this post with your network to spread valuable knowledge!

Let’s encourage more science-driven innovations in everyday foods!

🔗 https://ijpsr.com/bft-article/sensory-and-nutritional-profiling-of-sauropus-androgynus-leaves-by-means-of-drying-technologies/?view=fulltext

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Elevate your professional journey with Society of Pharmaceutical Sciences and Research (SPSR) — become a member today: https://spsrpharma.org

28/10/2025

Chewable Tablets: Innovation in Every Bite!

Chewable tablets are more than just kid-friendly dosage forms, they’re a rapidly evolving pharmaceutical innovation focused on patient comfort, precise dosing, and improved compliance.

From wet granulation to 3D printing, modern manufacturing technologies are transforming how chewables are designed, tasted, and accepted by patients across all age groups.

✅ A few key highlights:

• Multiple manufacturing techniques: wet granulation, dry granulation, direct compression, extrusion, melt & fluid-bed granulation, compression coating, and 3D printing

• Enhanced strength, taste-masking, and process efficiency depending on technology selection

• Process choice tailored to formulation needs, scale, and desired mouthfeel

• CDI (Chewability Design Index): a reliable tool to optimize chewability and ensure quality

• Patient acceptability is crucial, texture & hardness directly impact adherence
📌 Why it matters:

As patient-centric care expands, chewable tablets provide an inclusive pathway, especially for pediatrics, geriatrics, and patients with swallowing difficulties.

Chewable tablets represent the perfect blend of science and patient-focused design. Leveraging the right manufacturing strategy, while assessing chewability objectively using CDI can significantly elevate quality and compliance.

🔗 https://ijpsr.com/bft-article/a-comprehensive-review-of-formulation-methods-of-chewable-tablet-a-novel-approach/?view=fulltext

If you found this insightful, please share within your network and let’s spread awareness about patient-friendly dosage innovation!

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Elevate your professional journey with Society of Pharmaceutical Sciences and Research (SPSR) — become a member today: https://spsrpharma.org

07/10/2025

FDA September New Drug Approval

"A New Chapter in Urticaria Care: Meet Rhapsido (remibrutinib) — the First Oral BTK Inhibitor for Chronic Spontaneous Urticaria"

Rhapsido (remibrutinib) has been approved by the U.S. FDA as the first oral, targeted BTK inhibitor for adults with chronic spontaneous urticaria (CSU) who remain symptomatic despite standard antihistamine therapy.

This approval has the potential to reshape how patients and physicians manage a condition that has long been frustrating and unpredictable.

📍Why This Matters📍

▶️ Novel mechanism of action – Rhapsido targets Bruton's tyrosine kinase (BTK), helping curb downstream release of histamine and inflammatory mediators.

▶️ Oral, convenient dosing – 25 mg taken twice daily, with or without food.

▶️ Rapid and meaningful symptom relief

•Some patients achieved well-controlled disease as early as Week 2
• By Week 12, ~31% experienced complete resolution of hives and itch in trials vs ~10% on placebo

▶️ Favorable safety profile – Most common adverse events were mild (e.g. nasopharyngitis, headache). Does not require lab monitoring in routine use.

▶️ Unmet need addressed – Over half of CSU patients remain symptomatic despite antihistamines; prior options often required injections and were underutilized.

📌 A Few Important Considerations:

✔️ Be mindful of bleeding risk, especially in patients on anticoagulants — treatment may need interruption before surgical procedures.

✔️Avoid concomitant use with strong CYP3A4 inhibitors or inducers to prevent safety or efficacy issues.

✔️ Patients should avoid live or live-attenuated vaccines during treatment.

✔️ Not indicated for other types of urticaria beyond CSU in current labelling.

Rhapsido (remibrutinib) marks a bold step forward, combining mechanistic innovation, oral convenience, and robust clinical benefit, for patients with chronic spontaneous urticaria who’ve had limited options.

If you work in immunology, allergy, dermatology, or patient advocacy or know someone impacted by chronic hives, we encourage you to read more about this therapy and share this post with your network.

Together, we can help raise awareness and enable better patient outcomes.
Let’s spread the word because breakthroughs deserve to be heard.

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Elevate your professional journey with Society of Pharmaceutical Sciences and Research - SPSR — become a member today: https://spsrpharma.org

04/10/2025

Addressing the Global Threat of Antimicrobial Resistance (AMR): Innovations & Future Strategies

Antimicrobial resistance (AMR) is one of the biggest challenges to global health security. The rise of resistant pathogens threatens to render our current medicines ineffective,putting millions at risk.

Our recent article explores emerging approaches and rethinking strategies that can help safeguard the future of antimicrobial treatments.

Key Takeaways:

▪️Anti-virulent therapies that disarm pathogens instead of killing them
▪️Antimicrobial peptides with diverse mechanisms and minimal resistance risk
▪️Bacteriophage therapy: viruses that fight bacteria
▪️Plant-derived compounds & nanoparticles as innovative antimicrobials
▪️ Importance of surveillance, stewardship, and global collaboration
▪️ This is not just a scientific issue — it’s a call to action for researchers, healthcare professionals, policymakers, and the global community.

✅ The time to act is now — to ensure the medicines we rely on today remain effective for future generations.

📖 Read the full article to explore sustainable solutions, and let’s work together to combat AMR.

🔗 https://ijpsr.com/bft-article/addressing-the-global-threat-of-antimicrobial-resistance-emerging-approaches-innovations-and-rethinking-strategies-for-future-control/?view=fulltext

If you found this valuable, share it with your network and help amplify the message. Together, we can make a difference.

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Elevate your professional journey with Society of Pharmaceutical Sciences and Research - SPSR — become a member today: https://spsrpharma.org

19/09/2025

September FDA New Drug Approval: Inlexzo (gemcitabine) intravesical system

"New Hope in Bladder Cancer Treatment"

Bladder cancer remains one of the most challenging urological cancers, particularly for patients with BCG-unresponsive non-muscle invasive bladder cancer (NMIBC). Until now, treatment options have been limited, often leading to difficult clinical decisions.

Inlexzo (gemcitabine intravesical system) brings a new approach — a targeted, localized therapy designed to deliver sustained release of gemcitabine directly into the bladder.

Why this matters:

▪️Specifically developed for patients who do not respond to BCG therapy.
▪️Provides bladder-preserving therapy, reducing the need for radical surgery.
▪️Sustained intravesical delivery improves local tumor control while minimizing systemic toxicity.
▪️A promising step forward in expanding treatment options for high-risk NMIBC.

Innovation like this reflects the future of oncology, precision, targeted delivery, and improved quality of life for patients.

📖 Read more about this advancement and share with your network to raise awareness about this breakthrough in bladder cancer care.

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You can join 101st Society of Pharmaceutical Sciences and Research (SPSR) International Webinar On World Pharmacist Day 2025

Theme: “Think Health, Think Pharmacist”

Featuring the prestigious Society of Pharmaceutical Sciences and Research (SPSR) World Pharmacist Day Excellence Awards 2025 – celebrating contributions in research, education, pharmacy practice, and healthcare.

Join this global celebration of the pharmacy profession, where we honor outstanding contributions, inspire innovation, and spotlight the pivotal role of pharmacists in advancing healthcare worldwide.

📅 Date: 25th Sept 2025
⏰ Time: 8:00 PM – 10:00 PM IST
🗓️ Last Date for Registration: 24th Sept 2025
🗓️ Last Date for Award Nominations: 22nd Sept 2025
▶️ Live on YouTube: https: https://www.youtube.com/live/BcUPHOGweIA
🔗 Register for Webinar: https://docs.google.com/.../1FAIpQLSdIp2B1riEwvG.../viewform
🔗 Award Nominations: https://spsrpharma.org/award-registration?type=members

Celebrate World Pharmacist Day with Society of Pharmaceutical Sciences and Research (SPSR). Honoring Excellence, Inspiring the Future of Pharmacy. Be part of this milestone event that brings together researchers, academicians, healthcare leaders, and industry professionals from across the globe.

18/09/2025

Fighting cancer is hard, losing muscle shouldn’t be part of it.

What is chemotherapy-induced cachexia?

A treatment-linked syndrome of unintentional weight loss, muscle wasting, fatigue, and reduced function—distinct from general cancer wasting.

Why it happens:
• Chemo → pro-inflammatory cytokines & ROS
• Activation of NF-κB / MAPK → ubiquitin-proteasome muscle breakdown
• Mitochondrial dysfunction drives atrophy, low energy
• Appetite loss, nausea, fatigue → myosteatosis & further decline

Where we are now:

• Current supports: ghrelin agonists, SARMs, omega-3s, nutrition, exercise (helpful but inadequate)
• Mitoprotective compounds look promising to protect muscle

Bottom line:

We need a combined plan—targeted pharmacology + nutrition + exercise—while research advances nanotech/smart approaches to preserve muscle and quality of life.

👉 Full article: https://ijpsr.com/bft-article/cancer-chemotherapy-induced-cachexia-the-orphan-disease/?view=fulltext

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You can join 101st Society of Pharmaceutical Sciences and Research (SPSR) International Webinar On World Pharmacist Day 2025

Theme: “Think Health, Think Pharmacist”

Featuring the prestigious Society of Pharmaceutical Sciences and Research (SPSR) World Pharmacist Day Excellence Awards 2025 – celebrating contributions in research, education, pharmacy practice, and healthcare.

Join this global celebration of the pharmacy profession, where we honor outstanding contributions, inspire innovation, and spotlight the pivotal role of pharmacists in advancing healthcare worldwide.

📅 Date: 25th Sept 2025
⏰ Time: 8:00 PM – 10:00 PM IST
🗓️ Last Date for Registration: 24th Sept 2025
🗓️ Last Date for Award Nominations: 22nd Sept 2025
▶️ Live on YouTube: https://youtube.com/live/BcUPHOGweIA?feature=share
🔗 Register for Webinar: https://forms.gle/jeWwWD2KvKUUi7sh6
🔗 Award Nominations: https://spsrpharma.org/award-registration?type=members

Celebrate World Pharmacist Day with Society of Pharmaceutical Sciences and Research (SPSR). Honoring Excellence, Inspiring the Future of Pharmacy. Be part of this milestone event that brings together researchers, academicians, healthcare leaders, and industry professionals from across the globe.

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17/09/2025

101st Society of Pharmaceutical Sciences and Research (SPSR) International Webinar on World Pharmacist Day 2025

Theme: “Think Health, Think Pharmacist”

Highlighting the prestigious Society of Pharmaceutical Sciences and Research (SPSR) World Pharmacist Day Excellence Awards 2025 – recognizing exceptional achievements in research, education, pharmacy practice, and healthcare.

Be part of this global celebration of the pharmacy profession, where we honor excellence, inspire innovation, and showcase the vital role of pharmacists in shaping the future of healthcare worldwide.

Guests of Honor:

Dr. Donald A. Tomalia, Ph.D.
Adjunct Professor, University of Pennsylvania, USA
Affiliate Professor, Virginia Commonwealth University, Virginia, USA

🎙️ Esteemed Speaker:

Dr. Prakash Diwan – Former Founder Director, NIPER-Hyderabad & Former Director Grade Scientist, CSIR-IICT, Hyderabad, India.

Special Guest:

Dr. Mayank Singh
Principal Scientist & Director, The National Dendrimer & Nanotechnology Center, USA and Graduate Faculty & Adjunct Professor, Central Michigan University-College of Medicine, Michigan, USA

Invited Guest:

Dr. Shashi Alok
National President, Society of Pharmaceutical Sciences and Research (SPSR)

Convener:
Mrs. Monika Sabharwal
National Secretary, Society of Pharmaceutical Sciences and Research (SPSR)

📅 Date: 25th Sept 2025
⏰ Time: 8:00 PM – 10:00 PM IST
🗓️ Last Date for Registration: 24th Sept 2025
🗓️ Last Date for Award Nominations: 22nd Sept 2025

▶️ Live on YouTube: https://www.youtube.com/live/BcUPHOGweIA

🔗 Register for Webinar: https://docs.google.com/forms/d/e/1FAIpQLSdIp2B1riEwvGr1dtlE8LUUkl7d1V8KEmNnlwpf1oq11X1Q7Q/viewform

🔗 Award Nominations: https://spsrpharma.org/award-registration?type=members

Celebrate World Pharmacist Day with Society of Pharmaceutical Sciences and Research (SPSR). Honoring Excellence, Inspiring the Future of Pharmacy. Be part of this milestone event that brings together researchers, academicians, healthcare leaders, and industry professionals from across the globe.

13/09/2025

Buccal drug delivery: faster, smarter, & closer to the bloodstream.

Explore buccal films as an alternative to traditional oral meds & the signal is clear: placing an ultra-thin film on the inner cheek can bypass first-pass metabolism, boosting bioavailability, stability & therapeutic efficacy, without needles or swallowing challenges.

What’s inside the study (at a glance):

▪️ Performance metrics: swelling index, drug content, folding endurance, surface pH.
▪️ Manufacturing routes: solvent casting, hot-melt extrusion, freeze-drying.
▪️ Next-gen enablers: co-crystallization, lipid-based systems, solid dispersion, 3D printing, & AI-driven formulation design to improve solubility and stability, especially for poorly soluble drugs.
▪️ Real-world edge: higher bioavailability via first-pass bypass, potential for rapid onset, better patient compliance.

Challenges & where research is heading:

▪️Formulation stability and drug load capacity remain limiting factors.
▪️Promising solutions: nanotechnology (e.g., nanoparticles/nanofibers), smart polymers (pH/thermo-responsive), & multilayer films for controlled release and enhanced permeability.

Therapeutic opportunities:
Cancer • Cardiovascular disease • Smoking cessation • Hormone therapy • Pain management

Buccal film–based delivery is emerging as a transformative platform—combining efficacy with ease of use. As smart materials & nanotech mature, expect more precise release profiles, better patient experience & broader indications. The inner cheek may become one of the most valuable “addresses” in modern drug delivery.

Want the how, not just the hype? Complete article here → https://ijpsr.com/bft-article/revolutionizing-medicine-the-future-buccal-film-based-drug-delivery-system

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Elevate your professional journey with Society of Pharmaceutical Sciences and Research (SPSR) — become a member today: https://spsrpharma.org

29/08/2025

🏆 Society of Pharmaceutical Sciences and Research (SPSR) Excellence Awards 2025: Celebrate Academia • Research • Innovation

Great science deserves a bigger stage. We’re recognizing measurable impact, not job titles.

Who should apply?

• Students & early-career researchers
• Faculty
• Industry innovators
• Collaborations across sectors

Why it matters:

🌍 Visibility across 20+ countries
🎤 Recognition during the 100th SPSR Webinar (7 Sept 2025)
📈 CV boost, new collaborations, and community spotlight

Simple process:

• Choose your category (Academia / Research / Innovation)
• Add 3–5 proof points (data, DOIs/patents, outcomes, media)
• Optional short testimonial, proofread, submit

📅 Nomination deadline: 04-09-2025
👉 Nominate now: https://spsrpharma.org/award-registration?type=members

If you’ve done work that helps learners, patients, or the profession, put it on the record and repost to spread the word.

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Elevate your professional journey with Society of Pharmaceutical Sciences and Research - SPSR — become a member today: https://spsrpharma.org

Ijpsr Journal

06/11/2025

01/11/2025

31/10/2025

29/10/2025

28/10/2025

07/10/2025

04/10/2025

19/09/2025

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