08/09/2026
This study presents a pH-responsive, brain-targeted lipid nanoparticle (CD-TLNP@RGFP966) enabling efficient BBB transcytosis and lesion-triggered drug release for ischemic stroke. The nanocarrier promotes microglial M2 polarization and improves neuroinflammation and function, offering a novel anti-inflammatory treatment strategy.
🔗 https://doi.org/10.1080/14686996.2026.2699624