Epidemiology

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EPIDEMIOLOGY publishes original research from all fields of epidemiology. The journal also welcomes review articles and meta-analyses, novel hypotheses, descriptions and applications of new methods, and discussions of research theory or public health policy. We give special consideration to papers from developing countries.
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Estrogen Plus Progestin Hormone Therapy and Ovarian Cancer: A Complicated Relationship Exploredfrom
04/10/2020
Estrogen Plus Progestin Hormone Therapy and Ovarian Cancer: ... : Epidemiology

Estrogen Plus Progestin Hormone Therapy and Ovarian Cancer: A Complicated Relationship Explored

from

–progestin combined therapy on risk of ovarian cancer is less clear. Methods: We pooled primary data from five population-based case–control studies in the Ovarian Cancer Association Consortium, including 1509 postmenopausal ovarian cancer cases and 2295 postmenopausal controls. Information on p...

Maternal Thyroid Disorders and Risk of Autism Spectrum Disorder in Progenyfrom Rotem, Ran S.; Chodick, Gabriel; Shalev, ...
04/10/2020
Maternal Thyroid Disorders and Risk of Autism Spectrum... : Epidemiology

Maternal Thyroid Disorders and Risk of Autism Spectrum Disorder in Progeny

from Rotem, Ran S.; Chodick, Gabriel; Shalev, Varda; Davidovitch, Michael; Koren, Gideon; Hauser, Russ; Coull, Brent A.; Seely, Ellen W.; Nguyen, Vy T.; Weisskopf, Marc G.

trials of thyroid treatment during pregnancy reported null effects. To better understand these discrepant findings, we evaluated the association between maternal thyroid conditions and autism spectrum disorder (ASD), including examining the role of gestational thyroid-related hormone concentrations....

Accuracy of Blood Transfusion Records in a Population-based Perinatal Data Registryfrom Hutcheon, Jennifer A.; Chapinal,...
04/10/2020
Accuracy of Blood Transfusion Records in a Population-based ... : Epidemiology

Accuracy of Blood Transfusion Records in a Population-based Perinatal Data Registry

from Hutcheon, Jennifer A.; Chapinal, Nuria; Skoll, M. Amanda; Au, Nicholas; Lee, Lily

l Transfusion Registry for 2004–2015 deliveries. Using the Central Transfusion Registry records for red blood cell transfusion as the gold standard, we calculated the sensitivity, specificity, positive predictive value, and negative predictive value of the perinatal database variable for red blood...

Integrating Surveillance Data to Estimate Race/Ethnicity-specific Hysterectomy Inequalities Among Reproductive-aged Wome...
04/10/2020
Integrating Surveillance Data to Estimate... : Epidemiology

Integrating Surveillance Data to Estimate Race/Ethnicity-specific Hysterectomy Inequalities Among Reproductive-aged Women: Who’s at Risk?

from Gartner, Danielle R.; Delamater, Paul L.; Hummer, Robert A.; Lund, Jennifer L.; Pence, Brian W.; Robinson, Whitney R.

nce that address three challenges in the literature: exclusion of outpatient procedures, no hysterectomy prevalence adjustment, and paucity of non-White and non-Black estimates. Methods: We used surveillance data capturing all inpatient and outpatient hysterectomy procedures performed in North Carol...

Rural–Urban Differences in Adult Life Expectancy in Indonesia: A Parametric g-formula–based Decomposition Approachfrom S...
04/10/2020
Rural–Urban Differences in Adult Life Expectancy in... : Epidemiology

Rural–Urban Differences in Adult Life Expectancy in Indonesia: A Parametric g-formula–based Decomposition Approach

from Sudharsanan, Nikkil; Ho, Jessica Y.

ata come from the 2000, 2007, and 2014/2015 waves of the Indonesian Family Life Survey, a population-representative longitudinal study with mortality follow-up. We used Poisson regression and life tables to estimate rural–urban differences in life expectancy among 18,867 adult respondents ≥30 ye...

A Graphical Catalog of Threats to Validity: Linking Social Science with Epidemiologyfrom Matthay, Ellicott C.; Glymour, ...
04/09/2020
A Graphical Catalog of Threats to Validity: Linking Social... : Epidemiology

A Graphical Catalog of Threats to Validity: Linking Social Science with Epidemiology

from Matthay, Ellicott C.; Glymour, M. Maria

lenging, but these skills are often glossed over in training. Campbell and Stanley’s framework for causal inference has been extraordinarily influential in social science training programs but has received less attention in epidemiology. Their work, along with subsequent revisions and enhancements...

A Graphical Description of Partial Exchangeabilityfrom Sarvet, Aaron L.; Wanis, Kerollos Nashat; Stensrud, Mats J.; Hern...
04/09/2020
A Graphical Description of Partial Exchangeability : Epidemiology

A Graphical Description of Partial Exchangeability

from Sarvet, Aaron L.; Wanis, Kerollos Nashat; Stensrud, Mats J.; Hernán, Miguel A.

s) in depicting partial exchangeability and provide an illustrative example of when partial exchangeability might hold in the absence of complete exchangeability....

Effect Decomposition in the Presence of Treatment-induced Confounding: A Regression-with-residuals Approachfrom Wodtke, ...
04/09/2020
Effect Decomposition in the Presence of Treatment-induced... : Epidemiology

Effect Decomposition in the Presence of Treatment-induced Confounding: A Regression-with-residuals Approach

from Wodtke, Geoffrey T.; Zhou, Xiang

ntified. An alternative but similar set of effects, known as randomized intervention analogues to the natural direct effect (rNDE) and the natural indirect effect (rNIE), can still be identified in this situation, but existing estimators for these effects require a complicated weighting procedure th...

Aim for Clinical Utility, Not Just Predictive Accuracyfrom Sachs, Michael C.; Sjölander, Arvid; Gabriel, Erin E.
04/08/2020
Aim for Clinical Utility, Not Just Predictive Accuracy : Epidemiology

Aim for Clinical Utility, Not Just Predictive Accuracy

from Sachs, Michael C.; Sjölander, Arvid; Gabriel, Erin E.

e of actions in the clinical context, a formal decision rule based on the prediction has the potential to have a much broader impact. The use of a prediction-based decision rule should be formalized and preferably compared with the standard of care in a randomized trial to assess its clinical utilit...

Robust Metrics and Sensitivity Analyses for Meta-analyses of Heterogeneous Effectsfrom Mathur, Maya B.; VanderWeele, Tyl...
04/08/2020
Robust Metrics and Sensitivity Analyses for Meta-analyses... : Epidemiology

Robust Metrics and Sensitivity Analyses for Meta-analyses of Heterogeneous Effects

from Mathur, Maya B.; VanderWeele, Tyler J.

ion of true population effect sizes above this threshold. Second, we suggested reporting the proportion of effect sizes below a second, possibly symmetric, threshold in the opposite direction from the estimated mean. Our previous methods applied when the true population effects are approximately nor...

Toward Causally Interpretable Meta-analysis: Transporting Inferences from Multiple Randomized Trials to a New Target Pop...
04/07/2020
Toward Causally Interpretable Meta-analysis: Transporting... : Epidemiology

Toward Causally Interpretable Meta-analysis: Transporting Inferences from Multiple Randomized Trials to a New Target Population

from Dahabreh, Issa J.; Petito, Lucia C.; Robertson, Sarah E.; Hernán, Miguel A.; Steingrimsson, Jon A.

the target population and provide identification results. We show that the assumptions that allow inferences to be transported from all trials in the collection to the same target population have implications for the law underlying the observed data. We propose average treatment effect estimators th...

Toward Credible Patient-centered Meta-analysisfrom Manski, Charles F.
04/07/2020
Toward Credible Patient-centered Meta-analysis : Epidemiology

Toward Credible Patient-centered Meta-analysis

from Manski, Charles F.

a mean parameter across a hypothetical population of studies. The relevance of this methodology to patient care is not evident. Clinicians need to assess risks and choose treatments for populations of patients, not for populations of studies. This article draws on econometric research on partial ide...

Tracing the Origin of Food-borne Disease Outbreaks: A Network Model Approachfrom Jacobs, Rianne; Teunis, Peter; van de K...
04/07/2020
Tracing the Origin of Food-borne Disease Outbreaks: A... : Epidemiology

Tracing the Origin of Food-borne Disease Outbreaks: A Network Model Approach

from Jacobs, Rianne; Teunis, Peter; van de Kassteele, Jan

caused the outbreak. Methods: The network model we use replaces the classic geographic distance of a network by an effective distance so that two nodes connected by a long-range link may be more strongly connected than their geographic distance would suggest. Furthermore, the effective distance tran...

Community-wide Mortality Rates in Beijing, China, During the July 2012 Flood Compared with Unexposed Periodsfrom Yan, Me...
04/06/2020
Community-wide Mortality Rates in Beijing, China, During... : Epidemiology

Community-wide Mortality Rates in Beijing, China, During the July 2012 Flood Compared with Unexposed Periods

from Yan, Meilin; Wilson, Ander; Peel, Jennifer L.; Magzamen, Sheryl; Sun, Qinghua; Li, Tiantian; Anderson, G. Brooke

of deaths from natural causes triggered by disaster exposure. Here, we investigated community-wide mortality risk during this flood compared with rates in unexposed reference periods. Methods: We compared community-wide mortality rates on the peak flood day and the four following days to seasonally....

Do election laws restricting public road publicity reduce road traffic crashes and their consequences?from Nazif-Munoz, ...
04/03/2020
Do election laws restricting public road publicity reduce... : Epidemiology

Do election laws restricting public road publicity reduce road traffic crashes and their consequences?

from Nazif-Munoz, Jose Ignacio; Cuadrado, Cristóbal; Oulhote, Youssef; Spengler, John

ity must follow strict size standards to avoid visual contamination. This paper examines the impact of this regulation in reducing road traffic crashes. Methods: We obtained number of traffic injuries and fatalities per population from public records. A time-series difference-in-difference study, us...

Do temporal trends in cancer incidence reveal organ system connections for cancer etiology?from Yang, Wan; Terry, Mary B...
03/27/2020
Do temporal trends in cancer incidence reveal organ system... : Epidemiology

Do temporal trends in cancer incidence reveal organ system connections for cancer etiology?

from Yang, Wan; Terry, Mary Beth

s. Results: Temporal trends mapped to three major clusters in men involving six organ systems (digestive, endocrine, urinary, blood, respiratory, and male genital) and one cluster in women involving five systems (digestive, endocrine, urinary, and female genital). For both men and women, kidney, thy...

Residential proximity to intensive animal agriculture and risk of lymphohematopoietic cancers in the Agricultural Health...
03/13/2020
Residential proximity to intensive animal agriculture and... : Epidemiology

Residential proximity to intensive animal agriculture and risk of lymphohematopoietic cancers in the Agricultural Health Study

from Fisher, Jared A.; Freeman, Laura E. Beane; Hofmann, Jonathan N.; Blair, Aaron; Parks, Christine G.; Thorne, Peter S.; Ward, Mary H.; Jones, Rena R.

ural Health Study to permitted animal feeding operations in Iowa. We created metrics reflecting the intensity of animal exposures within 2 and 5km of participants’ residences, enumerating both total and inverse distance-weighted animal units (AUs), standardized by animal size and manure production...

Assessment of the Accuracy of Identification of Selected Disabilities and Conditions in Hospital Discharge Data for Preg...
03/13/2020
Assessment of the Accuracy of Identification of Selected... : Epidemiology

Assessment of the Accuracy of Identification of Selected Disabilities and Conditions in Hospital Discharge Data for Pregnant Women

from Schwartz, Naomi R.M.; Crane, Deborah A.; Doody, David R.; Schiff, Melissa A.; Mueller, Beth A.

sessed the accuracy of International Classification of Diseases version 9 (ICD9) codes for identifying selected physical, sensory, and intellectual conditions that may result in disability. As ICD9 codes were utilized until recently in most states, this information is useful to inform analyses with....

Toward Causally Interpretable Meta-analysis: Transporting Inferences from Multiple Randomized Trials to a New Target Pop...
03/09/2020
Toward Causally Interpretable Meta-analysis: Transporting... : Epidemiology

Toward Causally Interpretable Meta-analysis: Transporting Inferences from Multiple Randomized Trials to a New Target Population

from Dahabreh, Issa J.; Petito, Lucia C.; Robertson, Sarah E.; Hernán, Miguel A.; Steingrimsson, Jon A.

the target population and provide identification results. We show that assuming inferences are transportable from all trials in the collection to the same target population has implications for the law underlying the observed data. We propose average treatment effect estimators that rely on differen...

Robust Metrics and Sensitivity Analyses for Meta-analyses of Heterogeneous Effectsfrom Mathur, Maya B.; VanderWeele, Tyl...
03/09/2020
Robust Metrics and Sensitivity Analyses for Meta-analyses... : Epidemiology

Robust Metrics and Sensitivity Analyses for Meta-analyses of Heterogeneous Effects

from Mathur, Maya B.; VanderWeele, Tyler J.

ion of true effect sizes above this threshold. Second, we suggested reporting the proportion of effect sizes below a second, possibly symmetric, threshold in the opposite direction from the estimated mean. Our previous methods applied when the true effects are approximately normal, when the number o...

Aim for Clinical Utility, Not Just Predictive Accuracyfrom Sachs, Michael C.; Sjölander, Arvid; Gabriel, Erin E.
02/24/2020
Aim for Clinical Utility, Not Just Predictive Accuracy : Epidemiology

Aim for Clinical Utility, Not Just Predictive Accuracy

from Sachs, Michael C.; Sjölander, Arvid; Gabriel, Erin E.

e of actions in the clinical context, a formal decision rule based on the prediction has the potential to have a much broader impact. The use of a prediction-based decision rule should be formalized and preferably compared with the standard of care in a randomized trial to assess its clinical utilit...

Cosmetic tattooing and early onset basal cell carcinoma: a population-based case–control study from New Hampshirefrom Ba...
02/21/2020
Cosmetic tattooing and early onset basal cell carcinoma: a... : Epidemiology

Cosmetic tattooing and early onset basal cell carcinoma: a population-based case–control study from New Hampshire

from Barton, Dorothea Torti; Zens, Michael S.; Marmarelis, Eleni L.; Gilbert-Diamond, Diane; Karagas, Margaret R.

tudy of cases (ages 25-50 years), identified from a state-wide surveillance system, and age- and gender-matched controls, selected from driver’s license records, randomly assigned an anatomic site of the cases. Results: 156 cases (17%) with early onset basal cell carcinoma and 213 controls (26%) r...

TOWARDS CREDIBLE PATIENT-CENTERED META-ANALYSISfrom Manski, Charles F.
02/21/2020
TOWARDS CREDIBLE PATIENT-CENTERED META-ANALYSIS : Epidemiology

TOWARDS CREDIBLE PATIENT-CENTERED META-ANALYSIS

from Manski, Charles F.

a mean parameter across a hypothetical population of studies. The relevance of this methodology to patient care is not evident. Clinicians need to assess risks and choose treatments for populations of patients, not for populations of studies. This paper draws on econometric research on partial ident...

Community-wide mortality rates in Beijing, China, during the July 2012 flood compared to unexposed periodsfrom Yan, Meil...
02/21/2020
Community-wide mortality rates in Beijing, China, during... : Epidemiology

Community-wide mortality rates in Beijing, China, during the July 2012 flood compared to unexposed periods

from Yan, Meilin; Wilson, Ander; Peel, Jennifer L.; Magzamen, Sheryl; Sun, Qinghua; Li, Tiantian; Anderson, G. Brooke

r of deaths from natural causes triggered by disaster exposure. Here we investigated community-wide mortality risk during this flood compared to rates in unexposed reference periods. Methods: We compared community-wide mortality rates on the peak flood day and the four following days to seasonally m...

Tracing the Origin of Food-borne Disease Outbreaks: A Network Model Approachfrom Jacobs, Rianne; Teunis, Peter; van de K...
02/21/2020
Tracing the Origin of Food-borne Disease Outbreaks: A... : Epidemiology

Tracing the Origin of Food-borne Disease Outbreaks: A Network Model Approach

from Jacobs, Rianne; Teunis, Peter; van de Kassteele, Jan

break. The network model we use replaces the classic geographic distance of a network by an effective distance so that two nodes connected by a long-range link may be more strongly connected than their geographic distance would suggest. Furthermore, the effective distance transforms complex spatial....

Estrogen plus progestin hormone therapy and ovarian cancer: a complicated relationship exploredfrom
02/10/2020
Estrogen plus progestin hormone therapy and ovarian cancer: ... : Epidemiology

Estrogen plus progestin hormone therapy and ovarian cancer: a complicated relationship explored

from

–progestin combined therapy on risk of ovarian cancer is less clear. Methods: We pooled primary data from five population-based case–control studies in the Ovarian Cancer Association Consortium, including 1,509 postmenopausal ovarian cancer cases and 2,295 postmenopausal controls. Information on...

Validation of Questionnaire-based Case Definitions for Chronic Obstructive Pulmonary Diseasefrom Feinstein, Lydia; Wilke...
02/10/2020
Validation of Questionnaire-based Case Definitions for... : Epidemiology

Validation of Questionnaire-based Case Definitions for Chronic Obstructive Pulmonary Disease

from Feinstein, Lydia; Wilkerson, Jesse; Salo, Paivi M; MacNell, Nathaniel; Bridge, Matthew F; Fessler, Michael B; Thorne, Peter S; Mendy, Angelico; Cohn, Richard D; Curry, Matthew D; Zeldin, Darryl C

efinitions that incorporated self-reported physician diagnosis, respiratory symptoms, and/or smoking. We also validated a new definition that we developed empirically using gradient boosting, an ensemble machine learning method. Methods: Data came from 7,996 individuals aged 40-79 years who particip...

Long-term Exposure to Neighborhood Deprivation and Intimate Partner Violence Among Women: A UK Birth Cohort Studyfrom Ya...
02/07/2020
Long-term Exposure to Neighborhood Deprivation and Intimate ... : Epidemiology

Long-term Exposure to Neighborhood Deprivation and Intimate Partner Violence Among Women: A UK Birth Cohort Study

from Yakubovich, Alexa R.; Heron, Jon; Feder, Gene; Fraser, Abigail; Humphreys, David K.

from the Avon Longitudinal Study of Parents and Children in the United Kingdom, which followed our target sample, 7,219 women, from birth and their mothers (from pregnancy). At age 21, 2,128 participants self-reported the frequency of experiencing physical, psychological, or sexual intimate partner....

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When will Covid-19 antibody tests, which screen for whether someone has recovered from the disease, be available to the public?
Its Paramount for food kiosks & BCEs to maintain hygienic standards to prevent Respiratory Conditions;Thika-Nrb Hway
We need your help! We are searching for researchers and experts to join us and our partner IBM in a reference group to what analysis and data visualization is of interest in the handling of the corona virus. please help us share or join our experts group here: Fight Corona Virus_specialist group Like our page and follow the link to register your status Fight Corona Virus to help governments get an overview of the situation!
QxMD have created a collection of breaking research and editorial from peer reviewed journals on COVID-19 >>> https://qxmd.com/r/shared-collection/19211. It's free for all healthcare professionals to download the app and read from their personal device.
Peer reviewed and published cure for dry cough - cough aerosol virus containment This was just peer reviewed and published last month. It is easily one of the biggest peer reviewed and published medical discoveries of the year as a cough aerosol containment story. All of Dr. Miles Weinberger, MD., Pediatric Pulmonologist and chronic cough researcher's information is peer reviewed and published as noted below. First ever, in medical history, cure for dry chronic cough just published in Chest Journal of the American Thoracic Society and Annals of Allergy, Asthma and Immunology. (The type of dry cough that spreads virus and disease is cured.) After eluding medicine and science for over 300 years, here is Dr. Weinberger's peer reviewed and published, ONLY instant cure for dry chronic cough in the world by a 50 year chronic cough researcher from Rady Children's Hospital, San Diego, California. Cure the cough and stop the spread of virus and influenza. (Note: This cures the cough. This does NOT cure a virus.) All Dr. Miles Weinberger, MD's work and studies are peer reviewed and published in Chest Journal and Annals of Allergy, Asthma and Immunology. http://HabitCough.com Skype: StrategyTelevision
Articloe that may be of interest: To Battle the Coronavirus and Future Pandemic Threats We Must Have a 'Manhattan Project' NOW!
https://www.buzzsprout.com/697522 My cohost and I have an epidemiology podcast. We recently Covered the Wuhan Coronavirus. If interested please give it a listen. Feedback from the field is invaluable.
Hi, there . I would like to introduce myself to you .my name is Rashid Nuri a father of three trobule makers boys😂😂 and a husband of a lovely wife. I am just finishing up my MPH degree with certificate in Epidemiology ( which my focus) and another certificate in Health management and health policy. Right now I am working on the final touch of my internship research at Northwestern medical system . My question how I would get in Epidemiology job ? Please feel free to contact me or respond to my post.
अघिल्लो वर्ष सरकारले करिब १० करोड रूपैयाँबराबरको रेबिजविरुद्धको भ्याक्सिन खरिद गरेको थियो । तर, अबको बजेटमा बढेको मूल्यको अनुपातमा सरकारले बजेट नबढाउने हो भने आगामी वर्ष भ्याक्सिन अभाव हुने अधिकारीको भनाइ छ ।
You are cordially invited to join Vaccine Talk. Vaccine Talk is an evidenced based, civil discussion forum for all vaccination stances. Make sure you answer the 3 questions. https://www.facebook.com/groups/1872287639708735/
Looking for a social epidemiologist, early PhD-level or postdoctoral researcher Researchers at the University of California, San Francisco, are hiring a full-time researcher to support a recently research project funded by the NIH/National Institute on Aging. This is a superb opportunity to start a career in research, learning from, and publishing with, NIH-funded investigators. The analyst will work on the quantitative components of a mixed-methods study to evaluate access to long-term services and supports among older adults living alone with dementia. The quantitative work will leverage Health and Retirement Study (HRS) cohort data and other linked data sources. Coinvestigators leading the applicant's quantitative work are Drs. Jacqueline Torres and Maria Glymour in the Department of Epidemiology & Biostatistics at UCSF. The Principal Investigator is Dr. Elena Portacolone. The work will occur in Mission Hall on 16th street, in the Mission Bay Campus. It is also possible to partially work remotely. The position is funded for one year, with possibility of extension. This position is ideal for an experienced master’s level or early PhD-level candidate with experience managing and manipulating data from the HRS or a similar population-based cohort study, preferably in STATA and R. Intermediate to advanced knowledge of biostatistics and/or epidemiologic methods is highly desired. There will be opportunities for training and professional growth, including networking opportunities at UCSF and at regional and national conferences. Interested candidates should contact Jacqueline Torres ([email protected]) with questions. We will have an official posting very soon.
NICE UK are about to publish “guidelines” on Lyme Disease. Their epidemiology data is a shambles! This entire document states very clearly that there is no research on which to base advice or guidance on most areas of concern. Further it states that the research that it did use is of “poor” quality. We have launched a petition to stop this guideline being published. It is quite “wordy” as we needed to clarify the legal position at the beginning. Once past this part you will see some of the major areas of concern where they have used data outside of its intended use. With direct reference to epidemiology of Lyme Disease, the studies that NICE used to determine where Lyme was prevalent appear to be predominantly based on blood testing – which we know has low sensitivity (maybe as low as 20%). In at least one study EM rashes were excluded form the data and it isn’t clear whether any of the studies gave a positive Lyme Disease diagnosis to anyone who “only” had a clinical diagnosis. This means that their “guestimate” of 0.06 - 6.8 cases of Lyme disease per 100,000 people is grossly inaccurate and by virtue of underestimation, could also put the public at risk. The guideline needs to be stopped. The process that has created something this skewed and detrimental to patient safety and care needs to be revised. We value your support on this issue. Please sign and share the petition so we can try to make the necessary changes.