Journal of Clinical Gastroenterology

Journal of Clinical Gastroenterology Journal of Clinical Gastroenterology gathers the world's latest, most relevant clinical studies and

Journal of Clinical Gastroenterology gathers the world's latest, most relevant clinical studies and reviews, case reports, and technical expertise in a single source. Regular features include cutting-edge, peer-reviewed articles and clinical reviews that put the latest research and development into the context of your practice. Also included are biographies, focused organ reviews, practice management, and therapeutic recommendations

🌍 The World Gastroenterology Organisation (WGO) releases its updated Chronic Constipation Guideline—a global cascade app...
09/22/2025

🌍 The World Gastroenterology Organisation (WGO) releases its updated Chronic Constipation Guideline—a global cascade approach tailored to diverse healthcare settings.

An abstract is unavailable.

📌 High-dose esomeprazole-amoxicillin dual therapy (HDDT) is highly effective and better tolerated than furazolidone-base...
09/22/2025

📌 High-dose esomeprazole-amoxicillin dual therapy (HDDT) is highly effective and better tolerated than furazolidone-based quadruple therapy for H. pylori rescue.
ITT eradication: 93.6% vs. 86.9%
Side effects: 9% vs. 59%

A total of 209 patients with H. pylori infection, who had previously received ineffective treatment and visited an outpatient clinic, were randomly assigned to either the HDDT or FBQT groups. All patients underwent a 14-day treatment regimen, and the success rates of H. pylori eradication and safety...

🔍 EFTR vs. STER for upper GI lesions:New meta-analysis in JCG (n=725) shows EFTR yields higher en bloc & complete resect...
09/22/2025

🔍 EFTR vs. STER for upper GI lesions:
New meta-analysis in JCG (n=725) shows EFTR yields higher en bloc & complete resection rates with lower recurrence, but both are comparable in safety.

hniques used for resecting these lesions. This meta-analysis aims to compare the efficacy and safety of EFTR and STER in the treatment of upper gastrointestinal (GI) lesions. A systematic search was conducted in Embase, Scopus, Web of Science, Medline/PubMed, and Cochrane databases up to August 2024...

🧪 New in JCG: Noninvasive Disease Assessment in Eosinophilic Esophagitis (EoE)FeNO helps differentiate active EoE vs non...
08/28/2025

🧪 New in JCG: Noninvasive Disease Assessment in Eosinophilic Esophagitis (EoE)

FeNO helps differentiate active EoE vs non-EoE, while serum EDN, ECP, TARC & AEC show promise for monitoring disease activity.

🔗 Read free:

tions. Study: Nonasthmatic patients 18 years or above with suspected or diagnosed EoE, gastroesophageal reflux disease (GERD), and control individuals with indication for endoscopy were enrolled prospectively between November 2020 and May 2022. Participants underwent body plethysmography with fracti...

🌏 WGO News & EventsJoin us at the World Congress of Gastroenterology @ Australian Gastroenterology Week 2025 (WCOG@AGW25...
08/28/2025

🌏 WGO News & Events

Join us at the World Congress of Gastroenterology @ Australian Gastroenterology Week 2025 (WCOG@AGW25) in Melbourne 🇦🇺, Sept 19–22.
Theme: Emerging Frontiers in Gastroenterology & Hepatology

Details 👉 https://journals.lww.com/jcge/fulltext/2025/09000/world_gastroenterology_organization__wgo__news_and.1.aspx

Congress site 👉 https://www.wgo-agw25.gesa.org.au/

World Congress of Gastroenterology at Australian Gastroenterology Week 2025, Melbourne Australia 20-22 September 2025.

🎥 JCG podcast: Diagnostic Yield of Video Capsule Endoscopy (VCE) in Celiac Disease (CD) – Systematic Review & Meta-analy...
08/28/2025

🎥 JCG podcast: Diagnostic Yield of Video Capsule Endoscopy (VCE) in Celiac Disease (CD) – Systematic Review & Meta-analysis w/ Dr. Yaron Niv.
Hosted by Dr. Gengqing Song, discussing key findings, limitations & clinical impact.
🔗 Watch here:

Join us in face-to-face discussions with the authors of leading publications in the Journal of Clinical Gastroenterology. This series is an opportunity to further expand on the impetus behind the publication, main findings, limitations, and clinical implications. Today our host Dr...

🎧 JCG Podcast: Gastroesophageal Reflux Disease and Amazon.com with Dr. Richard WongHosted by Dr. Gengqing Song, explorin...
08/28/2025

🎧 JCG Podcast: Gastroesophageal Reflux Disease and Amazon.com with Dr. Richard Wong

Hosted by Dr. Gengqing Song, exploring the study’s motivation, findings, and clinical impact.
🔗 Listen here: https://journals.lww.com/jcge/pages/video.aspx?v=8

Join us in face-to-face discussions with the authors of leading publications in the Journal of Clinical Gastroenterology. This series is an opportunity to further expand on the impetus behind the publication, main findings, limitations, and clinical implications. Today our host Dr...

Biologics transformed IBD care, but not all patients respond. Our review highlights mechanisms, response rates, and pred...
08/21/2025

Biologics transformed IBD care, but not all patients respond. Our review highlights mechanisms, response rates, and predictive factors for nonresponse—helping guide better treatment strategies.

e patients are primary nonresponders and fail to show any response, while others relapse after an initial response, also known as secondary nonresponders. In this article, we review the mechanism of action of the currently available biological therapies for IBD, assessment of treatment response, the...

Many GERD “remedies” on Amazon lack solid science. Only weight loss + approved meds (PPIs, H2 blockers, PCABs, antacids)...
08/11/2025

Many GERD “remedies” on Amazon lack solid science. Only weight loss + approved meds (PPIs, H2 blockers, PCABs, antacids) have strong evidence. Consumers: check facts before buying.

ronic-commerce platform is oftentimes misleading and may not be supported by scientific medical evidence. Aims: The aim of this article is to critically and scientifically evaluate the Amazon.com platform as it relates to products that are being marketed for the treatment of gastroesophageal reflux....

📈 New in JCG: MASLD has surpassed hepatitis B as the leading cause of cirrhosis in China since 1992—especially affecting...
07/28/2025

📈 New in JCG: MASLD has surpassed hepatitis B as the leading cause of cirrhosis in China since 1992—especially affecting adults aged 15–49. Alarming trends from the GBD 2019 study demand urgent prevention.

e. Methods: Prevalence, incidence, disability-adjusted life-years, and mortality data were retrieved from the Global Burden of Disease study, 2019. Estimated annual percentage change was used to quantify the trends in the age-standardized prevalence rate and prevalence number of cirrhosis from 1990....

🔬 New in JCG: Is Lymphocytic Esophagitis (LyE) a distinct entity—or just a histologic pattern? This study reviews 381 ca...
07/28/2025

🔬 New in JCG: Is Lymphocytic Esophagitis (LyE) a distinct entity—or just a histologic pattern? This study reviews 381 cases and finds LyE lacks consistent clinical features. More research is needed.

mine if patients with LyE have distinct demographic or clinical characteristics when compared with patients with increased intraepithelial lymphocytes (IEL) in their esophageal biopsy. Methods: We conducted a retrospective review of all esophageal biopsies between 2008 and 2023 in 2 medical centers....

Zafer et al. tackle critical health disparities in Chronic Liver Disease (CLD). The review highlights inequities across ...
07/09/2025

Zafer et al. tackle critical health disparities in Chronic Liver Disease (CLD). The review highlights inequities across diagnosis, treatment, and outcomes, emphasizing the need for actionable solutions to achieve health equity. Essential reading!

tion. CLD disproportionately impacts racial, ethnic, sexual, and gender minorities. CLD is also more prevalent in populations experiencing challenging social determinants of health (SDOH) factors. Health disparities are prevalent across various forms of CLD, reflected in higher disease prevalence an...

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