Infectious Disease Special Edition (IDSE), is a bi-annual magazine that features features about infectious diseases and reviews written by ID experts. The magazine is read by infectious disease specialists, primary care physicians, epidemiologists, pharmacists, nurses and others involved in the treatment of infectious diseases. Each issue offers a collection of review articles written by leading clinicians and scientists. These reviews present topical, accurate, and comprehensive information on topics covering a wide range of patient populations and therapeutic areas. They are designed to serve as a “one-stop” resource for clinicians and researchers. IDSE takes into account the time constraints of its readers, and offers a compendium of clinical reference tools that are easy to read, with useful and clinical relevant drug tables and treatment algorithms designed to assist readers in their clinical practice.
World AIDS Day
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Today is World AIDS Day. The theme is "Everybody counts" where everyone has access to safe, effective, quality and affordable HIV services, medicines, diagnostics other health commodities for all people who need them. Universal health coverage means that all people receive the health services they need without experiencing financial hardship, including access to the full range of HIV services.
HIV-Positive Patients Not Getting Cardiovascular Care
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CDC: Too many missed opportunities to get people tested for HIV. http://www.idse.net/HIV-AIDS--STIs/Article/11-17/HIV-Testing-in-America-Delays-Missed-Opportunities/45339
Those with HIV at higher risk for CVD, but unlikely to receive statins. http://www.idse.net/HIVAIDS-STIs/article/11-17/People-With-HIV-Less-Likely-to-Receive-Statins/45329
FDA approves Juluca by ViiV Healthcare, the first complete treatment regimen containing only two drugs for the maintenance treatment of HIV infection.
http://www.idse.net/HIV-AIDS--STIs/Article/11-17/FDA-Approves-Juluca-First-2-Drug-Regimen-for-HIV/45306
This chart from the folks at @SanFranciscoOnlineMSN might come in handy for World Antibiotic Awareness Week. http://idse.net/Bacterial-Infections/Article/11-17/The-Rise-of-Antibiotic-Resistance/45255
This week is World Antibiotic Awareness Week. The rise of antibiotic resistance is leading to untreatable infections and a threat to global health, food security and drug development.
FDA Approves Prevymis CMV Prophylaxis
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GBS Major Cause of Infant Death and Stillbirths
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Top 5 Stories on the Web
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ACIP Recommends Shingrix for Adults 50 and Older
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ACIP recommends #Shingrix to the adult vaccination schedule for those 50 and older. http://www.idse.net/Immunology--Vaccination/Article/10-17/CDC-s-ACIP-Recommends-Adding-Shingrix-to-the-Adult-Vaccination-Schedule-/45062
The committee voted to include Shingrix (GlaxoSmithKline) in the adult vaccination recommendations for to prevent shingles in immunocompetent adults 50 and older.
9 Tools for a Better Antibiogram
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C. difficile Infection Management
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U.S. Food and Drug Administration issues warning about compounded ocular antibiotic causing blindness after common procedure. http://www.idse.net/Bacterial-Infections/Article/10-17/FDA-Compounded-Ocular-Antibiotic-May-Cause-Blindness/44931
Infectious Diseases Society of America
IDSA and HIVMA strongly urge the Trump administration to send emergency funding to avert public health crises in Puerto Rico and the U.S. Virgin Islands. We need to act quickly to fight infectious diseases in these areas. Full statement: http://bit.ly/2wO5UcI
Infectious Diseases and Vaccines
Herpes Vaccine Update: An Interview With Penn's Dr. Harvey Friedman.
90-90-90 could save many lives. http://www.idse.net/HIV-AIDS--STIs/Article/10-17/NHAS-Stopping-HIV-in-Its-Tracks/44928
The goal 90-90-90: Diagnosing 90% of all HIV-infected people, prescribing ART to 90% of those diagnoses and reaching virologic suppression among 90% of those receiving ART.
Winning the ‘Antibiotic Game’ With Pneumonia
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Experimental HIV Drugs Look Positive
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Experimental HIV drug looks promising. http://www.specialtypharmacycontinuum.com/Web-Only/Article/10-17/Single-Tablet-Combo-as-Effective-as-Current-HIV-Treatment/44853
If approved in the U.S., D/C/F/TAF would be the only complete regimen that could deliver the potential adherence benefit of a once-daily single-tablet regimen.
IDWeek: Preventing Pandemic Flu
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Make hand washing fun and educational http://www.idse.net/Pediatric-Infections/Article/10-17/Getting-Kids-to-Wash-Their-Hands-Make-It-Fun-and-Educational/44825
In the 30 days after the experiment began, the teachers reported they observed a 68% to 100% improvement in hand-washing behavior among the five classes.
IDWeek A novel avian flu virus causes concern about its ability to become a deadly pandemic.
http://www.idse.net/Respiratory-Tract-Infections--Influenza/Article/10-17/CDC-Novel-H7N9-Flu-Virus-Biggest-Concern-for-Pandemic-Capacity/44817
A novel avian influenza virus that is becoming more virulent and resistant, is being watched carefully because of fears of a pandemic.
Read our new monograph on rapid testing and stewardship. http://www.idse.net/Monographs-and-Whitepapers/Article/09-17/Improving-Antimicrobial-Stewardship-with-Faster-Susceptibility-Results-em-Use-of-the-Accelerate-PhenoTest-BC-Kit-em-/44717
This monograph describes clinical experience using the Accelerate Pheno™ system in shortening time to optimal antibiotic therapy with standardized antimicrobial stewardship intervention practices.
@CDC reports unhealthy trend: Record number of STDs. http://www.idse.net/HIV-AIDS--STIs/Article/09-17/At-More-than-2-Million-CDC-Reports-Record-High-Rates-of-STDs-in-U-S-/44706
There were 1.6 million new cases of chlamydia, 470,000 cases of gonorrhea and almost 28,000 cases of primary and secondary syphilis reported in 2016.
University of Cincinnati researchers finding out just how nasty ticks area
http://www.idse.net/From-Zoo-to-You/Article/09-17/Ticks-Are-Tougher-Nastier-Than-You-Thought/44694
Tick species appear to be expanding their range, which means the diseases they carry could be an emerging concern to new areas.
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Selzentry being studied for PrEP. http://www.idse.net/Bacterial-Infections/Article/09-17/Positive-Results-for-Selzentry-as-PrEP-Candidate-in-Women/44651
Fake antibiotics among the drugs sold by rogue pharmacies, FDA says. http://www.idse.net/Policy--Public-Health/Article/10-17/FDA-Takes-Action-Against-Rogue-Online-Pharmacies/44689
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The latest from InfectiousDiseaseSE (@IDSE_Online). Infectious Disease Special Edition (IDSE), is a comprehensive resource on treatments, procedures and infection prevention for healthcare providers. New York, NY
From a Phase II EMERGE trial, a new interferon, peginterferon lambda-1a, may help improve treatment for patients with hepatitis C (HCV). IDSE spoke with Andrew J. Muir, MD, MHS, the clinical director of hepatology at Duke University Medical Center, in Durham, N.C. about the novel interferon treatment.
“Improved tolerability, together with faster time to virologic response, supports the further assessment of lambda-based direct-acting antiviral combination regimens in patients chronically infected with HCV genotypes 1 or 4,” said Andrew J. Muir, MD, MHS, clinical director of hepatology at Duke Uni...
Interferon (IFN)-free therapies are on the horizon for patients with Hepatitis C (HCV) infection. In this article we share highlights from some of the trials of IFN-free therapies presented at the American Association for the Study of Liver Diseases (AASLD) meeting.
“We can see a light at the end of the tunnel,” said Guadalupe Garcia-Tsao, MD, professor of medicine at Yale University, New Haven, Conn., and chief of the section of digestive diseases at the Connecticut Veterans Affairs Healthcare System, West Haven, referring to a future that includes IFN-free re...
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Unsafe injections, that can lead to exposure of HIV, HCV and other IDs in patients, can happen anywhere. Read IDSE to hear more about a new CDC webinar drawing attention to this topic and to see the Safe Injection Practices Coalition's Injection Safety Checklist.
An infection spread by unsafe injection practices can happen anywhere. In 2008, it happened at an endoscopy clinic in Las Vegas. When a patient infected with hepatitis C was injected with propofol from a single-dose vial, backflow contaminated the syringe. Nurses reused the syringe to draw additiona...
Ezra Cohen, MD, a head and neck cancer specialist at the University of Chicago predicts HPV-positive oropharynx will be the most common virally associated cancer that physician's will see in the near future.
Chicago—A sharp rise in the incidence of human papillomavirus (HPV)–associated cancer of the oropharynx—in stark contrast to steady declines in HPV-unrelated oropharyngeal cancer due to decreases in smoking—virtually guarantees that clinicians will soon begin to see patients with this disease in the...
The CDC recently released summary guidance on the prevention of infectious disease for those who use illegal drugs. IDSE spoke with Diana Sylvestre, MD an assistant clinical professor of medicine at the University of California, San Francisco about the new guidelines.
The Centers for Disease Control and Prevention (CDC) and the U.S. Department of Health and Human Services (HHS) have issued a summary guidance on the prevention of infectious diseases in users of illicit drugs (MMWR Recomm Rep 2012;61[RR-5]:1-40). Focusing on integrated prevention services, the repo...
Research highlights on viral hepatitis and HIV from the Liver Meeting 2012.
Boston—The Liver Meeting 2012 featured the latest in research, treatment guidelines and advances in the field of hepatology. Here, we highlight some the most compelling presentations related to treatment for patients infected with the hepatitis C virus (HCV) and HIV.
A specialized Walgreens pharmacy program for HIV improved treatment adherence and persistence compared with traditional programs.
Community pharmacies that offer specialized services for HIV/AIDS patients may be more effective than traditional community pharmacies in improving adherence and persistence with antiretroviral therapy, according to a study in AIDS Patient Care and STDs (2012;26:526-531).
In response to the ongoing NECC meningitis outbreak, the National Association of Boards of Pharmacy has created an action plan to identify and inspect sterile and nonsterile compounding pharmacies.
The release of the NABP action plan on Tuesday came a day after the U.S. Senate Committee on Health, Education, Labor and Pensions, or HELP, sent a letter to all 50 state boards of pharmacy seeking details of how they oversee the nation’s more than 3,000 compounding pharmacies. The letter was part o...
A new report from the AHRQ showed that hospitalizations from Clostridium difficile infections have more than doubled over the past 10 years despite increased awareness about this pathogen.
Despite efforts by the U.S. Department of Health and Human Services and antimicrobial stewardship programs to combat Clostridium difficile infections (CDIs), the national rate of hospitalizations related to these infections is projected to more than double from 2001 to 2012, according to a report fr...
A new report from the AHRQ showed that hospitalizations from Clostridium difficile infections have more than doubled over the past 10 years despite increased awareness about this pathogen.
Despite efforts by the U.S. Department of Health and Human Services and antimicrobial stewardship programs to combat Clostridium difficile infections (CDIs), the national rate of hospitalizations related to these infections is projected to more than double from 2001 to 2012, according to a report fr...
A mandatory decolonization strategy for MRSA in the ICU prevents more bloodstream infections than standard screen-and-react methods, according to data presented at IDWeek 2012.
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