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Clinical Rheumatology Clinical Rheumatology - Journal of the International League of Associations for Rheumatology

2022 I
(1)

đź’Š The SMART study - first RCT on split-dose vs single-dose oral MTX in (n=253):âś…Split-dose not superior at 24 wks (pri...
14/09/2025

đź’Š The SMART study - first RCT on split-dose vs single-dose oral MTX in (n=253):
âś…Split-dose not superior at 24 wks (primary outcome)
âś… Better EULAR good response at 16 wks
âś… Reduced need for 2nd DMARD
⚠️ More AEs (intolerance, transaminitis)
https://t.co/tWmfgMoaCo

🔬 New study by Dr. Rodrigo Garcia Salinas et al.📖https://rdcu.be/eB76f💡D2M- affects ~ 9% of patients in real-world clin...
24/08/2025

🔬 New study by Dr. Rodrigo Garcia Salinas et al.
đź“–https://rdcu.be/eB76f
đź’ˇD2M- affects ~ 9% of patients in real-world clinical practice.
🧩Clinical and structural predictors such as psoriasis, smoking and joint damage are associated with D2M.
🧪Articular US is a key tool for identifying high-risk patients.

🔬In patients, high sodium-to-potassium ratio is linked to impaired myocardial perfusion, while potassium intake invers...
03/08/2025

🔬In patients, high sodium-to-potassium ratio is linked to impaired myocardial perfusion, while potassium intake inversely correlates with disease activity & inflammation
🧂↓ | 🥝🍌🥔↑ = ❤️&🔥↓
👉https://doi.org/10.1007/s10067-025-07608-4
🎓by Dr. Panagiota Anyfanti et al.

Hypothetical pathophysiological mechanisms of Kikuchi-Fujimoto disease associated with SARS-CoV-2 infection and COVID-19...
27/07/2025

Hypothetical pathophysiological mechanisms of Kikuchi-Fujimoto disease associated with SARS-CoV-2 infection and COVID-19 vaccines
👉https://rdcu.be/ex2DK

🧬Can therapy revolutionize treatment for refractory autoimmune diseases?👉https://rdcu.be/elAeKThis new review explores...
11/05/2025

🧬Can therapy revolutionize treatment for refractory autoimmune diseases?
👉https://rdcu.be/elAeK
This new review explores its potential in SLE, RA, SSc, Sjögren’s & more, with early data showing long-term remission in severe cases.

đź“š New review articleEctopic in tendons, ligaments & muscles present clinical challenges in rheumatology.This study out...
30/03/2025

đź“š New review article
Ectopic in tendons, ligaments & muscles present clinical challenges in rheumatology.
This study outlines pharmacological strategies for prevention & treatment, including NSAIDs, bisphosphonates, and vitamin K2 + D.
👉https://rdcu.be/efIPz

A disproportionality analysis of FAERS data (2012–2022) reveals distinct safety profiles of in :🔴 Baricitinib → Highe...
09/03/2025

A disproportionality analysis of FAERS data (2012–2022) reveals distinct safety profiles of in :
🔴 Baricitinib → Highest risk for CV events & cancer
🟠 Upadacitinib → ⬆️risk for respiratory & GI events
🟢 Tofacitinib → Lower cancer risk but more MSK AEs
📢 Personalized risk assessment is 🔑 for safe prescribing!
👉https://bit.ly/3Fijjlx

Late-Onset (lo-axSpA): A Distinct Subgroup? by Rodrigo Garcia Salinas and colleagues👉https://rdcu.be/d9uzU 📊 Key find...
11/02/2025

Late-Onset (lo-axSpA): A Distinct Subgroup?
by Rodrigo Garcia Salinas and colleagues
👉https://rdcu.be/d9uzU
đź“Š Key findings from the Reuma-check cohort:
✔️ 28% of axSpA cases started at ≥45 years.
✔️ More common in females (51%) & psoriasis (42%).
✔️ Lower NSAID response (52%) & HLA-B27 positivity (32%).
✔️ Shorter diagnosis delay (40 vs. 93 months) than early-onset axSpA
⚠️ lo-axSpA may require distinct diagnostic & treatment approaches.
https://doi.org/10.1007/s10067-024-07299-3

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