Asploro Open Access Publications (2026)

21/03/2026

Research Progress on the Selection of Anesthesia Methods for Elderly Patients Undergoing Hip Fracture Surgery

Rui Mao1, Hong Chang2*

1 Department of Anesthesiology, Shangjin Nanfu Hospital, Chengdu, China
2 Department of Anesthesiology, West China Hospital, , China

Asploro Journal of Biomedical and Clinical Case Reports
ISSN: 2582-0370
Article Type: Review Article
DOI: https://doi.org/10.36502/2026/ASJBCCR.6435
Asp Biomed Clin Case Rep. 2026 Jan 28;9(1):14-20

PDF:https://asploro.com/wp-content/uploads/2026/03/Research-Progress-on-the-Selection-of-Anesthesia-Methods-for-Elderly-Patients-Undergoing-Hip-Fracture-Surgery.pdf

HTML: https://asploro.com/asjbccr/research-progress-on-the-selection-of-anesthesia-methods-for-elderly-patients-undergoing-hip-fracture-surgery/

Abstract
Hip fractures occur frequently in elderly patients, and there is a broad clinical consensus favoring early surgical intervention. However, hip fracture surgery is often prolonged, and elderly patients commonly present with multiple comorbidities, reduced tolerance to anesthetic agents, diminished metabolic capacity, and delayed postoperative recovery. Inappropriate intraoperative anesthesia methods can therefore increase the risk of postoperative cognitive dysfunction and instability of vital signs, leading to greater financial burden and impaired postoperative quality of life. Consequently, the selection of an appropriate anesthesia method is of significant importance for improving surgical safety and clinical outcomes. Based on these considerations, this article reviews the selection of anesthesia methods for elderly patients undergoing hip fracture surgery.

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This review discusses anesthesia selection for elderly patients undergoing hip fracture surgery, focusing on safety and postoperative outcomes.

21/03/2026

Research Progress on the Correlation Between Delirium and Dementia

Yu Cai1*

1 Department of Anesthesiology, West China Hospital, , Chengdu, Sichuan, China

Asploro Journal of Biomedical and Clinical Case Reports
ISSN: 2582-0370
Article Type: Review Article
DOI: https://doi.org/10.36502/2026/ASJBCCR.6434
Asp Biomed Clin Case Rep. 2026 Jan 16;9(1):07-13

PDF:https://asploro.com/wp-content/uploads/2026/01/Research-Progress-on-the-Correlation-Between-Delirium-and-Dementia.pdf

HTML: https://asploro.com/asjbccr/research-progress-on-the-correlation-between-delirium-and-dementia/

Abstract
Delirium is an acute confusional state characterized by inattention, altered level of consciousness, and cognitive dysfunction, whereas dementia is an insidious, chronic, and progressive loss of previously acquired cognitive abilities. The occurrence of delirium is an independent risk factor for subsequent dementia, and conversely, patients with dementia have a significantly higher risk of developing delirium compared to the general population. Although the close relationship between the two is recognized, the specific mechanisms underlying their interaction remain unclear. In daily life and clinical practice, timely assessment of cognitive function and effective intervention in individuals experiencing delirium may potentially slow cognitive decline and even prevent the onset or progression of dementia. This article reviews the research on the correlation between delirium and dementia, exploring ways to mitigate or even reverse further cognitive deterioration in delirious patients.

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This review examines the bidirectional relationship between delirium and dementia, focusing on risk, mechanisms, and early intervention.

04/03/2026

A Case with Detailed Renal Study by the Three-Dimensional Computed Tomography (3D-CT) Reconstruction

Katsunori Ogura1, Hiroshi Bando1,2iD*, Hisako Yamash*ta1, Yoshinobu Kato1, Yoshikane Kato1

1 Kanaiso Hospital, Komatsushima, Tokushima, Japan
2 Medical Research/ , Tokushima, Japan

Asploro Journal of Biomedical and Clinical Case Reports
ISSN: 2582-0370
Article Type: Case Report
DOI: https://doi.org/10.36502/2026/ASJBCCR.6433
Asp Biomed Clin Case Rep. 2026 Jan 14;9(1):01-06

PDF:https://asploro.com/wp-content/uploads/2026/01/A-Case-with-Detailed-Renal-Study-by-the-Three-Dimensional-Computed-Tomography-3D-CT-Reconstruction.pdf

HTML: https://asploro.com/asjbccr/a-case-with-detailed-renal-study-by-the-three-dimensional-computed-tomography-3d-ct-reconstruction/

Abstract
Authors have been involved in the reconstruction procedure of three-dimensional computed tomography (3D-CT) by Synapse Vincent based on Artificial Intelligence (AI). The patient was a 62-year-old male, and 3D-CT images showed renal cysts and stones. His clinical problems included high blood pressure, cholelithiasis, alcohol consumption, obesity, liver dysfunction, renal cyst, renal stones, and left renal ureteral obstruction. As the transparent image of 3D-CT reconstruction, the right ureter was traceable, but the left ureter was not. The left kidney shows contrast medium accumulation in the renal calyx, with no urine flow due to the renal stone. Thus, 3D-CT reconstruction would be beneficial.

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Three-dimensional computed tomography reconstruction using AI-based Synapse Vincent identified renal cysts, stones, and ureteral obstruction.

04/03/2026

A Case with Hepatic Hemangioma, Duplicated and Horseshoe Kidney Detected by The Reconstruction of Three-Dimensional Computed Tomography (3D-CT)

Katsunori Ogura1, Hiroshi Bando1,2iD*, Hisako Yamash*ta1, Yoshinobu Kato1, Yoshikane Kato1

1 Kanaiso Hospital, Komatsushima, Tokushima, Japan
2 Medical Research/ , Tokushima, Japan

Asploro Journal of Biomedical and Clinical Case Reports
ISSN: 2582-0370
Article Type: Case Report
DOI: https://doi.org/10.36502/2025/ASJBCCR.6432
Asp Biomed Clin Case Rep. 2025 Dec 28;8(3):301-305

PDF:https://asploro.com/wp-content/uploads/2026/01/A-Case-with-Hepatic-Hemangioma-Duplicated-and-Horseshoe-Kidney-Detected-by-The-Reconstruction-of-Three-Dimensional-Computed-Tomography-3D-CT.pdf

HTML: https://asploro.com/asjbccr/a-case-with-hepatic-hemangioma-duplicated-and-horseshoe-kidney-detected-by-the-reconstruction-of-three-dimensional-computed-tomography-3d-ct/

Abstract
Authors have reported several research on the reconstruction of three-dimensional computed tomography (3D-CT) by Synapse Vincent, Japan. The patient was an 87-year-old female with abdominal discomfort. Abdominal CT and 3D-CT images have suggested the presence of hepatic cysts and hemangioma, as well as duplicated and horseshoe kidney. Current disease seems to be the inherited disease, and it is involved in the Congenital Anomalies of the Kidney and the Urinary Tract (CAKUT). Consequently, reconstruction of 3D-CT seems to be beneficial and useful for diagnosing, clinical practice, and research. Further development of artificial intelligence (AI) technique will be expected in the future.

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Three-Dimensional Computed Tomography reconstruction using Synapse Vincent aided diagnosis of hepatic cysts and CAKUT-related renal anomalies, with future AI potential.

04/03/2026

Energy and Nutritional Aspects of Dietary Fiber in Human

Masahiro Bando1, Hirohisa Urasaki2, Hiroshi Bando1,2iD*

1 and Medical Research, Tokushima, Japan
2 Yoshinogawa Hospital, Tokushima, Japan

Journal of Health Care and Research
ISSN: 2582-8967
Article Type: Commentary
DOI: https://doi.org/10.36502/2025/hcr.6250
J Health Care and Research. 2025 Nov 25;6(3):69-71

PDF:https://asploro.com/wp-content/uploads/2025/12/Energy-and-Nutritional-Aspects-of-Dietary-Fiber-in-Human.pdf

HTML: https://asploro.com/jhcr/energy-and-nutritional-aspects-of-dietary-fiber-in-human/

Abstract
Carbohydrates are defined as “sugars + dietary fiber,” and dietary fiber has been considered indigestible and therefore provides no energy (0 kcal/g). Much dietary fiber is fermented by intestinal bacteria to produce short-chain fatty acids (SCFAs) such as acetic acid, propionic acid, and butyric acid. These SCFAs are partially absorbed by the host and used for metabolic energy, so dietary fiber contains “available energy”. Consequently, dietary fiber is generally classified into 3 groups and converted into energy equivalents, which are non-absorbed fibers as 0 kcal/g, partially fermented fibers as 1 kcal/g, and fairly completely fermented fibers as 2 kcal/g.

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Dietary fiber isn’t zero-calorie; it’s fermented to produce SCFAs that supply usable energy, with fibers yielding roughly 0–2 kcal/g depending on fermentation.

14/02/2026

Proposal of Type 5 Diabetes from IDF for Global Awareness

Hiroshi Bando1,2iD*

1 Medical Research/ , Tokushima, Japan
2 Japan Low Carbohydrate Diet Promotion Association, Kyoto, Japan

Diabetes Research: Open Access
Article Type: Editorial
DOI: https://doi.org/10.36502/2025/droa.6195
Diab Res Open Access. 2025 Dec 08;6(1):24-27

PDF:https://asploro.com/wp-content/uploads/2025/12/Proposal-of-Type-5-Diabetes-from-IDF-for-Global-Awareness.pdf

HTML: https://asploro.com/droa/proposal-of-type-5-diabetes-from-idf-for-global-awareness/

Abstract
Diabetes has been studied and managed internationally by the American Diabetes Association (ADA), the European Association for the Study of Diabetes (EASD), the Japan Diabetes Association (JDA), and so on. The International Diabetes Federation (IDF) proposed “type 5 diabetes (T5D)” in April 2025. T5D mainly develops due to chronic malnutrition during childhood, particularly in low-income countries, affecting an estimated 20 to 25 million people. It shows low body weight and insulin deficiency, previously known as malnutrition-related diabetes (MNRD). Its novel perspective typing will contribute to more awareness and discussion for medicine, education, public health, the economy, and social factors such as poverty and nutritional disparities.

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Type 5 Diabetes (T5D), defined by IDF in 2025, is malnutrition-related diabetes affecting 20M+ people worldwide, highlighting major global health inequities.

14/02/2026

Possible Investigation of Charisma Judge Using Micro-Vibration Status for Visually Impaired

Akiyo Yoshioka1, Yu Nishikiori1, Hiroshi Bando1,2iD*, Motohiko Morizaki3, Masahiro Bando1,2, Yoshihiro Uto4

1 New Elderly Association (NEA), Tokushima, Japan
2 Medical Research/ , Tokushima, Japan
3 Mental Sports Research, Artistar Japan, Tokyo, Japan
4 Graduate School of Technology, Industrial and Social Sciences, , Tokushima, Japan

Asploro Journal of Biomedical and Clinical Case Reports
ISSN: 2582-0370
Article Type: Case Report
DOI: https://doi.org/10.36502/2025/ASJBCCR.6431
Asp Biomed Clin Case Rep. 2025 Nov 15;8(3):296-300

PDF:https://asploro.com/wp-content/uploads/2025/12/Possible-Investigation-of-Charisma-Judge-Using-Micro-Vibration-Status-for-Visually-Impaired.pdf

HTML: https://asploro.com/asjbccr/possible-investigation-of-charisma-judge-using-micro-vibration-status-for-visually-impaired/

Abstract
Authors and co-researchers have conducted clinical research on psychosomatic medicine. The current case is a 21-year-old university student who has been visually impaired due to retinoblastoma since birth. He was raised in a music therapy environment and is good at playing the piano, singing, and academic activities, gaining valuable experience. His daily life on campus was featured on a Japanese national educational television program. He received Charism Judge, which applies micro-vibration analysis of the human head, eyes, and face, as well as the vestibulo-ocular reflex (VOR). His overall mental score was 222.2 points, classified as the hope category level. Although he is almost blind, Charism Judge can evaluate his novel psychosomatic measurement.

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Case study of a visually impaired university student with retinoblastoma assessed by Charism Judge, showing novel psychosomatic evaluation.

14/02/2026

Non-Ablative Laser Treatment for Rosacea

Pedro Rolando López Rodríguez1iD*, Lázaro Pérez Rodríguez2, Mercedes Gil García3

1 First- and second-degree Specialist in General Surgery; Specialist in Aesthetic Medicine; Medical Laser Assistant Professor; Assistant Researcher and Consulting Professor, WAAS Medical Center, Madrid, Spain
2 Specialist in Laser Medicine and Phototherapy in Dermo-aesthetic Pathologies; Researcher in the Development of Dermatological and Vascular Lesions using Lasers, WAAS Medical Center, Madrid, Spain
3 Licentiate and Master in General Genetic Engineering with specialization in Virology and Bacteriology, WAAS Medical Center, Madrid, Spain

Asploro Journal of Biomedical and Clinical Case Reports
ISSN: 2582-0370
Article Type: Case Report
DOI: https://doi.org/10.36502/2025/ASJBCCR.6430
Asp Biomed Clin Case Rep. 2025 Nov 14;8(3):291-95

PDF:https://asploro.com/wp-content/uploads/2025/12/Non-Ablative-Laser-Treatment-for-Rosacea.pdf

HTML: https://asploro.com/asjbccr/non-ablative-laser-treatment-for-rosacea/

Abstract
Introduction: Rosacea is a chronic inflammatory dermatosis that primarily affects the midface (cheeks, nose, chin, forehead), although it can also affect other areas of the body such as the scalp, neck, auricle, chest, and eyes.
Objective: To describe the clinical characteristics of a patient with extensive rosacea injuries on her skin and their possible treatment with non-ablative lasers.
Clinical Case: Observational study in a 62-year-old patient with a dermatological diagnosis of rosacea, who was treated with non-ablative lasers with excellent results, leaving no scars and resolving the injuries in just five sessions.
Conclusions: Rosacea is a benign dermatological lesion, and treatment with non-ablative lasers is effective, leaving no scars and requiring no additional treatments.

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Case report of a 62-year-old patient with extensive rosacea successfully treated with non-ablative lasers, achieving scar-free resolution in five sessions.

04/02/2026

Human being and Sweeteners: The History of Honey and Sugar

Hiroshi Bando1,2iD*, Hidehisa Urasaki2, Masahiro Bando1, Akiyo Yoshioka1

1 Medical Research/ , Tokushima, Japan
2 Yoshinogawa Hospital, Tokushima, Japan

Diabetes Research: Open Access
Article Type: Commentary
DOI: https://doi.org/10.36502/2025/droa.6194
Diab Res Open Access. 2025 Nov 06;6(1):20-23

PDF:https://asploro.com/wp-content/uploads/2025/12/Human-being-and-Sweeteners-The-History-of-Honey-and-Sugar.pdf

HTML: https://asploro.com/droa/human-being-and-sweeteners-the-history-of-honey-and-sugar/

Abstract
Recently, health and medical problems related to carbohydrates, sugar, and sweets have been under discussion. Historically, wall paintings in the Altamira Cave in Spain depict people harvesting honey, suggesting honey as the earliest natural sweetener. White sugar originated from India before the Common Era by boiling down sugarcane juice. Since the Industrial Revolution, people have been able to obtain enough sugar at low cost. The widespread use of sugar has had a profound impact on food culture, tastes, and society around the world. Current issues regarding carbohydrates in modern society include the development of alternative sweeteners such as aspartame, sucralose, stevia, and erythritol.

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Health issues linked to carbohydrates and sugar are rising, from ancient honey use to modern sweeteners like aspartame, sucralose, stevia, and erythritol.

04/02/2026

Recent Perspectives for Clinical Effects of Whey Protein on Post-Prandial Hyperglycemia (PPH)

Hiroshi Bando1,2iD*, Hidehisa Urasaki1,2, Masahiro Bando1

1 Medical Research/ , Tokushima, Japan
2 Yoshinogawa Hospital, Tokushima, Japan

Asploro Journal of Biomedical and Clinical Case Reports
ISSN: 2582-0370
Article Type: Commentary
DOI: https://doi.org/10.36502/2025/ASJBCCR.6429
Asp Biomed Clin Case Rep. 2025 Oct 24;8(3):287-90

PDF:https://asploro.com/wp-content/uploads/2025/11/Recent-Perspectives-for-Clinical-Effects-of-Whey-Protein-on-Post-Prandial-Hyperglycemia-PPH.pdf

HTML: https://asploro.com/asjbccr/recent-perspectives-for-clinical-effects-of-whey-protein-on-post-prandial-hyperglycemia-pph/

Abstract
As the development of continuous glucose monitoring (CGM) progresses, the clinical effects of whey protein on postprandial hyperglycemia (PPH) have been identified. Whey protein includes milk protein, yogurt, casein, almond milk, and so on. Milk protein supplementation has been shown to reduce fasting blood glucose (FBG) by -1.83 mg/dL, fasting insulin by -1.06 μU/mL, and HOMA-IR by -0.27. Whey protein was administered in doses of 0–30 g before breakfast, and the incremental area under the curve (AUC) was reduced when taking 15–30 g. Premeal whey showed a lower glucose peak by -1.0 mmol/L (-18 mg/dL) in patients with gestational diabetes mellitus (GDM). Further research development is expected for PPH.

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Whey protein before meals reduces post-prandial hyperglycemia, lowers glucose peaks, improves insulin response, and shows promise for future PPH management.

Asploro Open Access Publications

21/03/2026

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