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The Live Longer Podcast Helping you to add years to your life and life to your years. Guidance on your path to Radiant Health

16/09/2025

Ikigai, a Japanese concept often translated as "life's purpose" or "reason for being," represents the intersection of what you love, what you're good at, what the world needs, and what you can be paid for. This philosophy goes far beyond career satisfaction, it encompasses a deep sense of meaning and direction that permeates every aspect of life. In the Japanese worldview, ikigai isn't necessarily a grand calling but can be found in simple daily pleasures and meaningful connections, whether that's tending a garden, preparing a meal with care, or nurturing relationships with family and community.
Research consistently links having a strong sense of purpose with increased longevity and better health outcomes. Studies of centenarians in Japan's Blue Zones, areas with unusually high concentrations of people living past 100, reveal that those with a clear ikigai tend to live longer, more fulfilling lives. This purpose-driven approach to living appears to reduce stress, improve cardiovascular health, and strengthen immune function while providing the motivation to maintain healthy habits and social connections. The beauty of ikigai lies in its accessibility; it doesn't require dramatic life changes but rather encourages a mindful awareness of what brings meaning to your daily existence, creating a sustainable foundation for both mental well-being and physical longevity.

16/09/2025

Is spermidine the next longevity breakthrough, or just another wellness trend? Mark J. Kaylor dives deep into this naturally occurring compound that's been making waves in the anti-aging world. While spermidine shows genuine promise for promoting autophagy (your cells' cleanup system), supporting cardiovascular health, and potentially extending lifespan in animal studies, the research in humans is still limited Spermidine and the Search for Longevity. What's fascinating is that this molecule appears most beneficial for older adults with declining natural levels, while healthy young individuals might see little benefit Spermidine and the Search for Longevity. The key takeaway? Spermidine earns its place as a promising newcomer — not a trend to chase, but a tool to explore wisely alongside proven lifestyle practices like time-restricted eating, polyphenol-rich diets, and quality sleep Spermidine and the Search for Longevity. If you're considering supplementation, choose food-based forms over synthetic versions for better absorption. Read the full analysis to separate the hype from the science and discover whether spermidine deserves a spot in your wellness routine.
https://radianthealthproject.org/articles-2-2/longevity-2/spermidine-and-the-search-for-longevity/

15/09/2025

What if the key to living longer and healthier isn’t just what you eat or how much you move—but why you get up in the morning?

In "Purpose: The Secret Ingredient to Radiant Health and Longevity", Mark J. Kaylor reveals that having a clear sense of meaning and purpose is as vital to our health as sleep, nutrition, and exercise. Drawing from studies of aging populations and large longitudinal research, the article demonstrates that people who live with purpose enjoy not only longer lives, but better quality of life: fewer disabilities, faster recovery from illness, reduced risk of depression, improved sleep, and enhanced cognitive resilience. It also explores what happens when purpose fades, during retirement, after major life transitions, and offers practical strategies for rediscovering or cultivating purpose through small, intentional acts that align with our core values. In short: purpose isn’t just feel-good, it’s a powerful, biology-anchored pillar of radiant health.

https://radianthealthproject.org/articles-2-2/health-healing/purpose-the-secret-ingredient-to-radiant-health-and-longevity/

10/09/2025

The two best predictors of longevity.

10/09/2025
11/08/2025

The combination of acetyl L-carnitine (ALCAR) and alpha lipoic acid (ALA) is one of the most compelling — and surprisingly underutilized — strategies for supporting mitochondrial health and function. Pioneered by Dr. Bruce Ames and colleagues at the University of California, Berkeley, this pairing gained attention in the early 2000s for its remarkable ability to reverse aspects of mitochondrial decline in aged animals. In Ames’ research, ALCAR improved the transport of fatty acids into mitochondria, boosting energy production, while ALA reduced oxidative stress within the mitochondria and regenerated other antioxidants like vitamin C, vitamin E, and glutathione. Together, they didn’t just enhance mitochondrial function — they restored it toward a more youthful state, improving energy output, reducing oxidative damage, and even revitalizing physical and cognitive performance in older test subjects.

Given the current explosion of interest in mitochondrial health — with countless new supplements promising “cellular energy” and “longevity” benefits — it’s striking how rarely this well-researched, affordable, and synergistic combination is discussed. Instead of chasing unproven trends, the ALCAR + ALA duo offers a science-backed foundation that addresses two fundamental issues of mitochondrial aging: fuel delivery and oxidative protection. For anyone serious about sustaining energy metabolism, reducing oxidative burden, and protecting long-lived proteins from glycation and crosslinking damage, revisiting this classic pairing could be one of the most overlooked yet impactful moves available today.

07/08/2025

Recent research presents compelling evidence linking higher Omega-3 Index levels with greater longevity. The Omega-3 Index is a measure of the amount of EPA and DHA—two key omega-3 fatty acids—found in red blood cell membranes. Individuals with a high Omega-3 Index show a noticeably slower decline in survival over time compared to those with lower levels. Over a span of seven years, the percentage of people still living remains significantly higher in the group with elevated omega-3 status, suggesting a protective, life-extending benefit.

This association supports a growing body of research indicating that omega-3 fatty acids play a vital role in cardiovascular, brain, and overall cellular health. By helping to reduce inflammation, improve heart rhythm, support healthy blood lipids, and enhance arterial function, omega-3s may reduce the risk of chronic diseases that contribute to premature mortality. While correlation does not prove causation, the trend shown here adds weight to recommendations encouraging regular consumption of omega-3-rich foods like fatty fish, flaxseeds, and walnuts—or supplementation when needed—as part of a long-term health and longevity strategy.

05/08/2025

Your Brain Was Never Meant to Be Plastic.

Our brains were never meant to be soaked in plastic — yet that's exactly what's happening in our modern world.
A fascinating new article from the Radiant Health Project reveals how everyday plastics and phthalates are acting as endocrine disruptors, quietly sabotaging our neurological health and accelerating brain aging.
The alarming reality:
Microplastics have been detected in human brain tissue
These chemicals mimic hormones like estrogen and thyroid hormones that are crucial for brain function
Research links phthalate exposure to reduced memory, altered brain structure, and higher dementia risk
Common exposure sources include food packaging, cosmetics, receipts, and even household dust
The brain impact: Chronic exposure to plastic-derived chemicals contributes to neuroinflammation, brain fog, memory loss, and premature cognitive decline. Since our brains are exquisitely hormone-sensitive, when these synthetic chemicals disrupt our natural hormone signaling, the neurological consequences can be profound.
Taking action: The good news? We can reduce our exposure and support our brain's natural detox pathways:
✓ Use glass/stainless steel instead of plastic containers ✓ Minimize processed, packaged foods
✓ Choose organic produce when possible
✓ Invest in quality water filtration
✓ Support detox with cruciferous vegetables, turmeric, and regular exercise
This isn't about fear — it's about making informed choices to protect our most precious asset: our cognitive health.
Your brain holds your memories, creativity, and dreams. It's worth protecting.
https://journeytoradianthealth.org/articles-2-2/brain-02/the-plastic-brain-how-everyday-toxins-age-your-mind/

31/07/2025
17/07/2025

The 7 Channels of Elimination: A Holistic Perspective on Supporting the Body’s Natural Detox Pathways
by Mark J Kaylor
In this illuminating article, we explore the body’s seven primary channels of elimination—the liver, lungs, kidneys, colon, skin, blood, and lymphatic system—and how each plays a vital role in the ongoing process of detoxification. Rather than promoting harsh cleanses or quick fixes, the piece offers a grounded, holistic perspective that honors the body’s innate wisdom. Through nourishing foods, proper hydration, movement, breath, rest, and herbal allies, we can gently support these pathways and restore their natural rhythms. Detoxification, as the article reminds us, isn’t a seasonal fad but a daily function of radiant living. When we nurture all seven channels—supporting the gut microbiome, enhancing circulation, sweating with purpose, calming the nervous system, and feeding the organs what they need—we invite vitality to flow more freely. This is detox as nature intended: steady, subtle, and deeply rooted in balance.
https://journeytoradianthealth.org/the-7-channels-of-elimination-a-holistic-perspective-on-supporting-the-bodys-natural-detox-pathways/

16/07/2025

Quick Summary: Conventional wisdom warns against high cholesterol, yet research reveals a more nuanced picture—especially when we look at those who live the longest. While low cholesterol is often considered ideal, studies of centenarians and elderly

09/07/2025

How to Heal in a Society that Profits from Our Illness: Reclaiming Wholeness in a System Built on Disconnection
by Mark J Kaylor
In a world saturated with wellness advice and health products, many still find it painfully difficult to truly heal. Why? Because the deeper structures of our society — our food systems, healthcare models, economic pressures, and cultural narratives — often work against genuine well-being. This blog explores what it means to seek health and wholeness in a system that profits from chronic illness and disconnection. More than just a critique, this piece offers a hopeful reminder that healing is still possible — and radically powerful — when we begin to remember what wholeness truly means.
https://journeytoradianthealth.org/articles-2-2/health-healing/how-to-heal-in-a-society-that-profits-from-our-illness-reclaiming-wholeness-in-a-system-built-on-disconnection/

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