
25/09/2025
🌟 WCLC 2025: Real-world outcomes in EGFR-mutant NSCLC
A multicentre retrospective study presented at WCLC 2025 examined second-line chemotherapy following first-line targeted therapy in 91 patients with EGFR-mutant advanced NSCLC.
Median progression-free survival was just over five months, median overall survival under a year, and response rates were modest, highlighting the limited durability of standard chemotherapy in this setting.
Dr Igor Gómez-Randulfe notes that these findings provide pragmatic real-world benchmarks and emphasise the ongoing need for more effective post-first-line strategies and personalised treatment approaches.
👉 https://touchoncology.com/insight/wclc-2025-egfr-mutant-nsclc/