Retina

15/07/2025

OPEN ACCESS Article
SURGICAL AND REFRACTIVE OUTCOMES OF A NOVEL MODIFIED SCLERA-FIXATED RAYNER INTRAOCULAR LENS USING GORE-TEX SUTURE
Hsiao, Chung-Hao MD; Cheng, Yuan-Shao MD; Lo, Wen-Jung MS; Chen, Hung-Ju MD; Chang, Chia-Jen PhD
Retina 45(7):p 1339-1346, July 2025
This study reviewed 103 cases of a novel modified sclera-fixated Rayner IOL with Gore-Tex suture. Postoperative visual acuity significantly improved, with acceptable refractive outcomes, manageable complications, and a mean prediction error of −0.81D, demonstrating the efficacy and safety of this surgery.
https://journals.lww.com/retinajournal/fulltext/2025/07000/surgical_and_refractive_outcomes_of_a_novel.13.aspx

15/07/2025

LONG-TERM OUTCOMES OF SECONDARY INTRAOCULAR LENS SURGERIES USING THE HAPTIC EXTERNALIZATION SCLERAL SUTURE TECHNIQUE
Bison, Henry S. MD; Thompson, John T. MD
Retina 45(7):p 1332-1338, July 2025
A retrospective study of 223 eyes with IOL fixation using the haptic externalization scleral suture technique. There was a visual acuity improvement from logMAR 1.14 ± 0.05 (20/250-2) preoperatively to 0.48 ± 0.04 (20/63 + 1) postoperatively (P < 0.0001). The rate of IOL dislocation postoperatively requiring reoperation was 9/223(4%). This study demonstrates the long-term success of the haptic externalization scleral suture technique.
https://journals.lww.com/retinajournal/abstract/2025/07000/long_term_outcomes_of_secondary_intraocular_lens.12.aspx

14/07/2025

CAN CHANGES ON OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY PREDICT EXUDATIVE ACTIVITY ON OPTICAL COHERENCE TOMOGRAPHY IN EYES WITH NEOVASCULAR AGE-RELATED MACULAR DEGENERATION?
Souied, Eric H. MD, PhD; Amoroso, Francesca MD; Baillif, Stéphanie MD, PhD; Devin, François MD; Weber, Michel MD, PhD; Colantuono, Donato MD; Blanco-Garavito, Rocio MD; Miere, Alexandra MD, PhD
Retina 45(7):p 1323-1331, July 2025
This study aimed to evaluate whether OCTA can predict exudative activity changes in nAMD treated with ranibizumab. While OCTA might not forecast imminent exudation, it provides valuable insights into MNV flow. The findings suggest neovascularization remodeling and exudation may represent distinct processes in nAMD.
https://journals.lww.com/retinajournal/abstract/2025/07000/can_changes_on_optical_coherence_tomography.11.aspx

14/07/2025

OPEN ACCESS Article
EFFECTS OF FARICIMAB LOADING PHASE ON DIABETIC MACULAR EDEMA IN REAL-WORLD SETTING
Scampoli, Alessandra MD; Carlà, Matteo Mario MD, FEBO; Grieco, Giulia MD; Catalani, Roberta MD; Governatori, Lorenzo MD; Rizzo, Stanislao MD; Caporossi, Tomaso MD, PhD
Retina 45(7):p 1313-1322, July 2025
The loading phase with faricimab in patients with resistant diabetic macular edema offered good functional results and efficacy on optical coherence tomography biomarkers such as fluid and hyperreflective foci. The effect on microvascular architecture instead remains controversial.
https://journals.lww.com/retinajournal/fulltext/2025/07000/effects_of_faricimab_loading_phase_on_diabetic.10.aspx

.carla

14/07/2025

VISUAL OUTCOMES AND ADHERENCE CHALLENGES IN PROLIFERATIVE DIABETIC RETINOPATHY ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR MONOTHERAPY IN THE CLINICAL PRACTICE SETTING
Maturi, Jay R. BS; Boucher, Nick BSc; Fernando, Rusirini BSc; Scott, Adrienne W. MD
Retina 45(7):p 1303-1312, July 2025
Real-world adherence to antivascular endothelial growth factor for proliferative diabetic retinopathy is poor: >40% are lost to follow-up within 1 year, and 87% remain nonadherent to the Diabetic Retinopathy Clinical Research Network Protocol S monotherapy regimen of antivascular endothelial growth factor injections.
https://journals.lww.com/retinajournal/abstract/2025/07000/visual_outcomes_and_adherence_challenges_in.9.aspx

11/07/2025

CHANGES OF CYTOKINES IN AQUEOUS HUMOR OF RETINOBLASTOMA WITH INTRAVITREAL MELPHALAN
Zhou, Xiaoting MD; Meng, Fengxi MD; Ren, Hui MD; Xu, Binbin MD; Lin, Xintong MD; Qian, Jiang MD, PHD; Xue, Kang MD
Retina 45(7):p 1295-1302, July 2025
Ocular toxicity is a concern in eye preservation treatments for retinoblastoma. Our initial investigation focused on the analysis of cytokine levels in the aqueous humor of patients undergoing intravitreal melphalan treatment for retinoblastoma. Elevated cytokine levels after intravitreal melphalan administration may be associated with ocular toxicities.
https://journals.lww.com/retinajournal/abstract/2025/07000/changes_of_cytokines_in_aqueous_humor_of.8.aspx

nts with congenital cataracts as controls. The clinical features of the patients were recorded before and after IVM. Twenty-seven cytokines concentrations in aqueous humor samples collected from these patients were measured by a suspension array system. Results: The levels of Interleukin (IL)-8, IL-...

11/07/2025

Rt-PA-ASSISTED VITREORETINAL SURGERY FOR OPEN GLOBE INJURY WITH SUPRACHOROIDAL HEMORRHAGE
Shi, Tingkun MMed; Huang, Yuqiang PhD; Xia, Honghe MMed; Jin, Chuang MMed; Ke, Xixuan MMed; Liao, Xulong MMed; Zhang, Qi MMed; Cheng, Yinglin MMed; Chen, Haoyu MD
Retina 45(7):p 1286-1294, July 2025
Suprachoroidal injection of recombinant tissue plasminogen activator, followed by drainage of suprachoroidal hemorrhage combined with vitreoretinal surgery, can efficiently drain suprachoroidal hemorrhage and restore ocular structure and visual function at an early stage. Retinal loss is the risk factor for poor visual and anatomical outcomes.
https://journals.lww.com/retinajournal/abstract/2025/07000/rt_pa_assisted_vitreoretinal_surgery_for_open.7.aspx

10/07/2025

OUTCOMES OF PERSISTENT EXUDATIVE RETINAL DETACHMENTS AFTER PROTON BEAM IRRADIATION FOR CHOROIDAL MELANOMA
Steinkerchner, Megan S. MD; Lane, Anne M. MPH; Gragoudas, Evangelos S. MD; Kim, Ivana K. MD, MBA; Wu, Frances MD
Retina 45(7):p 1279-1285, July 2025
The following retrospective analysis found similar clinical outcomes, including the rates of radiation retinopathy, neovascular glaucoma, and enucleation, between conservative versus surgical management of persistent exudative retinal detachments in choroidal melanoma. Refractory exudative retinal detachments were shown to be a significant risk factor for neovascular glaucoma within the cohort.
https://journals.lww.com/retinajournal/abstract/2025/07000/outcomes_of_persistent_exudative_retinal.6.aspx

10/07/2025

OPEN ACCESS Article
MACULAR EDEMA AND SILICONE OIL TAMPONADE
Clinical Features, Predictive Factors, and Treatment
Ferro Desideri, Lorenzo MD; Aissani, Meriam MSc; Bernardi, Enrico MD; Zinkernagel, Martin MD, PhD; Anguita, Rodrigo MD
Retina 45(7):p 1271-1278, July 2025
Prolonged silicone oil tamponade and retinectomy have been identified as significant risk factors for macular edema in retinal surgery. These findings emphasize the need for careful patient counselling and close postoperative monitoring.
https://journals.lww.com/retinajournal/fulltext/2025/07000/macular_edema_and_silicone_oil_tamponade__clinical.5.aspx

09/07/2025

OPEN ACCESS Article
ENDOTHELIAL CELL LOSS AFTER PARS PLANA VITRECTOMY WITH SILICONE OIL TAMPONADE
Feng, Limiao MD; Zhang, Yuming MD; Pan, Jiandong MD, PhD
Retina 45(7):p 1262-1270, July 2025
This study compares endothelial cell loss after pars plana vitrectomy with silicone oil tamponade in rhegmatogenous and tractional retinal detachment. Patients with tractional retinal detachment showed greater loss (9.17% vs. 3.39%). Age, lens status, and combined surgeries were key factors, emphasizing careful monitoring, particularly in older patients with tractional retinal detachment.
https://journals.lww.com/retinajournal/fulltext/2025/07000/endothelial_cell_loss_after_pars_plana_vitrectomy.4.aspx

09/07/2025

CLINICAL FEATURES AND OUTCOMES OF LATE RECURRENT RHEGMATOGENOUS RETINAL DETACHMENT
Ghalibafan, Seyyedehfatemeh MD; Santiago Volante, Vincent Angelo MD; Kim, Colin BS; Rohowetz, Landon J. MD; Flynn, Harry W. Jr MD; Yannuzzi, Nicolas A. MD
Retina 45(7):p 1255-1261, July 2025
A study of 69 eyes from 1,879 cases examined late recurrent retinal detachment, defined as redetachment 3 months ≤ after repair. Despite a 93% reattachment rate, visual outcomes were poor. No significant differences were found between late recurrent retinal detachments after 3 versus 6 months, although later recurrences had worse visual acuity.
https://journals.lww.com/retinajournal/abstract/2025/07000/clinical_features_and_outcomes_of_late_recurrent.3.aspx

09/07/2025

RESCUE PNEUMATIC RETINOPEXY FOR RETINAL DETACHMENT IN VITRECTOMIZED EYES
Adams, Olufemi E. MD; Kumar, Sandeep MD; Pecaku, Aurora MD; Shroff, Daraius MD; Rizvi, Fatima BA; Momenaei, Bita MD; Yu, Michael D. MD; Klufas, Michael A. MD; Muni, Rajeev H. MD; Yonekawa, Yoshihiro MD
Retina 45(7):p 1247-1254, July 2025
In this retrospective multicenter study involving 38 eyes, retinal reattachment after a single pneumatic retinopexy procedure was achieved in 71.1% of vitrectomized eyes, with better outcomes in eyes without a retinal detachment history. Pneumatic retinopexy can be considered a less invasive option for retinal reattachment in select vitrectomized eyes.
https://journals.lww.com/retinajournal/abstract/2025/07000/rescue_pneumatic_retinopexy_for_retinal_detachment.2.aspx