Embryoman (2025)

15/08/2025

The Uterine Wall of Fame (UWOF) is a collection of real IVF success stories from people who faced tough odds -- low-grade embryos, repeated failures, low AMH, mosaic results, and more.

UWOF #18 is one of those stories!

After cancer, male factor infertility, and four retrievals where nearly all embryos arrested before blastocyst, a single 3AB embryo finally led to a healthy 17-week pregnancy at age 42.

✅ Visit the UWOF to read this full story and others like it (link in the comments, free to access & no subscription required).

💌 Have a story of your own? Can be anonymous or named -- link to the form is in the comments.

⚠️ The UWOF is a project by Remembryo / Embryoman, created to give hope to others going through IVF with challenging situations. These stories are personal, not medical advice. What works for one may not work for all—always check with your doctor before making treatment changes.

𝑵𝒐𝒕𝒆 𝒕𝒉𝒂𝒕 𝒕𝒉𝒊𝒔 𝒑𝒐𝒔𝒕 𝒊𝒔 𝒇𝒓𝒐𝒎 𝒎𝒚 𝒑𝒖𝒃𝒍𝒊𝒄-𝒇𝒂𝒄𝒊𝒏𝒈 𝒑𝒂𝒈𝒆. 𝑻𝒉𝒆 𝒔𝒂𝒎𝒆 𝒑𝒐𝒔𝒕 𝒄𝒂𝒏 𝒃𝒆 𝒇𝒐𝒖𝒏𝒅 𝒊𝒏 𝒎𝒚 𝒑𝒓𝒊𝒗𝒂𝒕𝒆 𝒈𝒓𝒐𝒖𝒑, 𝒘𝒉𝒊𝒄𝒉 𝑰'𝒍𝒍 𝒍𝒊𝒏𝒌 𝒊𝒏 𝒕𝒉𝒆 𝒄𝒐𝒎𝒎𝒆𝒏𝒕𝒔.

14/08/2025

IVF add-ons are extra tests, procedures or treatments offered alongside standard IVF, often for an additional cost.

The Italian Society of Fertility and Sterility and Reproductive Medicine (SIFES-MR) has now published guidance on 28 IVF add-ons. They reviewed the latest studies to 2024 and included guidance from other leading fertility groups, including ASRM, ESHRE, HFEA and ISAR.

Supported for certain patients:

- Karyotype analysis (severe male factor)
- Hysteroscopy (abnormal ultrasound)
- Embryo glue (multiple failed transfers)
- Corticosteroids (autoimmune/medical need)
- Rescue IVM (fertility preservation in cancer)
- PGT-A (advanced age or recurrent loss)
- Chronic endometritis testing/treatment (multiple failed transfers)

Not supported: IMSI, endometrial scratch, ERA testing, time-lapse, mitoscore, routine assisted hatching.

Insufficient evidence/research only: PICSI, growth hormone, DHEA, intraovarian PRP, intrauterine PRP, MACS, Zymot, AOA, rescue ICSI, ni-PGT, microbiome analysis/treatment, immunological testing and treatment, intrauterine hCG, G-CSF.

The authors write that IVF add-ons may help in certain situations or for specific patients, but many do not have enough reliable evidence to support routine use. The panel is especially concerned about add-ons that may carry safety risks or are promoted without clear proof of benefit.

✅ Check out all the details on Remembryo, link is in the comments.

✉️ Like this post? Explore more topics and sign up for my free Friday newsletter to stay updated on the latest IVF research (link in the comments).

𝐇𝐚𝐯𝐞 𝐲𝐨𝐮 𝐭𝐫𝐢𝐞𝐝 𝐚𝐧𝐲 𝐈𝐕𝐅 𝐚𝐝𝐝-𝐨𝐧𝐬? 𝐖𝐡𝐢𝐜𝐡 𝐨𝐧𝐞𝐬? 𝐃𝐢𝐝 𝐭𝐡𝐞𝐲 𝐡𝐞𝐥𝐩? 𝑵𝒐𝒕𝒆 𝒕𝒉𝒂𝒕 𝒕𝒉𝒊𝒔 𝒑𝒐𝒔𝒕 𝒊𝒔 𝒇𝒓𝒐𝒎 𝒎𝒚 𝒑𝒖𝒃𝒍𝒊𝒄-𝒇𝒂𝒄𝒊𝒏𝒈 𝒑𝒂𝒈𝒆. 𝑻𝒉𝒆 𝒔𝒂𝒎𝒆 𝒑𝒐𝒔𝒕 𝒄𝒂𝒏 𝒃𝒆 𝒇𝒐𝒖𝒏𝒅 𝒊𝒏 𝒎𝒚 𝒑𝒓𝒊𝒗𝒂𝒕𝒆 𝒈𝒓𝒐𝒖𝒑, 𝒘𝒉𝒊𝒄𝒉 𝑰'𝒍𝒍 𝒍𝒊𝒏𝒌 𝒊𝒏 𝒕𝒉𝒆 𝒄𝒐𝒎𝒎𝒆𝒏𝒕𝒔.

13/08/2025

Researchers tested a noninvasive MRI-like tool that reads an embryo’s metabolic health, accurately predicting which would stop developing and potentially helping select the healthiest for transfer.

Embryologists have many tools to rank embryos for transfer, like grading, time lapse imaging and PGT-A. But these reveal little about the embryo’s metabolism — the chemical processes that help the embryo grow and develop.

A key part of this metabolism involves lipid droplets, tiny fat storage bubbles that fuel mitochondria, the cell’s “powerhouses.” Too few may limit growth, while too many can signal stress.

In a new study by Giulia Sivelli and colleagues, researchers tested a new technique called micro magnetic resonance spectroscopy (micro MRS) that can detect fatty acids stored in lipid droplets.

The technique works on the same basic principles as an MRI, the hospital imaging tool that uses strong magnets and radio waves to create detailed pictures of the inside of the body. Instead of producing an image, micro MRS measures the chemical fingerprint of the embryo, without the need for a biopsy.

Using it on cow embryos and eggs, they found it could predict with high accuracy which embryos would arrest before the blastocyst stage, and could distinguish mature from immature eggs with moderate accuracy.

Human studies will be needed to confirm whether these measurements can predict implantation or live birth, but the ability to detect embryo health through metabolic signatures is promising.

In the future, micro MRS might not only identify embryos likely to arrest but also help rank developing embryos by their potential for a successful pregnancy.

✅ Check out all the details on Remembryo, link is in the comments.

✉️ Like this post? Explore more topics and sign up for my free Friday newsletter to stay updated on the latest IVF research (link in the comments).

𝑵𝒐𝒕𝒆 𝒕𝒉𝒂𝒕 𝒕𝒉𝒊𝒔 𝒑𝒐𝒔𝒕 𝒊𝒔 𝒇𝒓𝒐𝒎 𝒎𝒚 𝒑𝒖𝒃𝒍𝒊𝒄-𝒇𝒂𝒄𝒊𝒏𝒈 𝒑𝒂𝒈𝒆. 𝑻𝒉𝒆 𝒔𝒂𝒎𝒆 𝒑𝒐𝒔𝒕 𝒄𝒂𝒏 𝒃𝒆 𝒇𝒐𝒖𝒏𝒅 𝒊𝒏 𝒎𝒚 𝒑𝒓𝒊𝒗𝒂𝒕𝒆 𝒈𝒓𝒐𝒖𝒑, 𝒘𝒉𝒊𝒄𝒉 𝑰'𝒍𝒍 𝒍𝒊𝒏𝒌 𝒊𝒏 𝒕𝒉𝒆 𝒄𝒐𝒎𝒎𝒆𝒏𝒕𝒔.

11/08/2025

A new global analysis examined trends in gynecological disorders among women of childbearing age between 1990 and 2021.

In 2021, infertility affected 110 million women, PCOS affected nearly 66 million, fibroids affected 85 million, and endometriosis affected 21 million. PMS was the most common condition overall, with almost 890 million cases worldwide.

Over the past three decades, infertility cases rose by 84%, PCOS by 89%, and fibroids by 77%, while endometriosis cases declined by 10%.

✅ I haven't reviewed this one in detail, but you can find a link to original study in the comments.

✉️ Like this post? Explore more topics and sign up for my free Friday newsletter to stay updated on the latest IVF research (link in the comments).

𝑵𝒐𝒕𝒆 𝒕𝒉𝒂𝒕 𝒕𝒉𝒊𝒔 𝒑𝒐𝒔𝒕 𝒊𝒔 𝒇𝒓𝒐𝒎 𝒎𝒚 𝒑𝒖𝒃𝒍𝒊𝒄-𝒇𝒂𝒄𝒊𝒏𝒈 𝒑𝒂𝒈𝒆. 𝑻𝒉𝒆 𝒔𝒂𝒎𝒆 𝒑𝒐𝒔𝒕 𝒄𝒂𝒏 𝒃𝒆 𝒇𝒐𝒖𝒏𝒅 𝒊𝒏 𝒎𝒚 𝒑𝒓𝒊𝒗𝒂𝒕𝒆 𝒈𝒓𝒐𝒖𝒑, 𝒘𝒉𝒊𝒄𝒉 𝑰'𝒍𝒍 𝒍𝒊𝒏𝒌 𝒊𝒏 𝒕𝒉𝒆 𝒄𝒐𝒎𝒎𝒆𝒏𝒕𝒔.

11/08/2025

(Advertisement by IVF Media Ltd.)

Check out the IVF Abroad - Patient's Guide 2025, showcasing the best countries for IVF treatment abroad! With this guide you can check clinic popularity, success rates, IVF treatment costs and legislation. The guide is comprehensive and includes 105 pages with 11 of the most popular countries, without ads.

Link in the comments.

08/08/2025

A new study examined whether PGT-A changes how quickly IVF patients achieve a live birth.

PGT-A screens embryos for chromosome number before transfer. It can help avoid transferring embryos with abnormal chromosomes, which are less likely to implant or may lead to miscarriage.

However, whether it speeds up time to a successful pregnancy is debated.

In this study by Yael Eliner and colleagues, PGT-A was linked to a shorter time to live birth for patients aged 38 or older, with higher 1-year live birth rates compared to those who did not use PGT-A.

In younger patients under 38, there was no difference in time to pregnancy or 1-year live birth rates. This is likely because younger patients have a higher chance of producing a euploid embryo compared to older patients. Other studies have shown that transferring a euploid vs a high quality untested embryo have similar chances of live birth for younger patients.

✅ I haven't reviewed this one in detail, but you can find a link to original study in the comments.

✉️ Like this post? Explore more topics and sign up for my free Friday newsletter to stay updated on the latest IVF research (link in the comments).

𝑵𝒐𝒕𝒆 𝒕𝒉𝒂𝒕 𝒕𝒉𝒊𝒔 𝒑𝒐𝒔𝒕 𝒊𝒔 𝒇𝒓𝒐𝒎 𝒎𝒚 𝒑𝒖𝒃𝒍𝒊𝒄-𝒇𝒂𝒄𝒊𝒏𝒈 𝒑𝒂𝒈𝒆. 𝑻𝒉𝒆 𝒔𝒂𝒎𝒆 𝒑𝒐𝒔𝒕 𝒄𝒂𝒏 𝒃𝒆 𝒇𝒐𝒖𝒏𝒅 𝒊𝒏 𝒎𝒚 𝒑𝒓𝒊𝒗𝒂𝒕𝒆 𝒈𝒓𝒐𝒖𝒑, 𝒘𝒉𝒊𝒄𝒉 𝑰'𝒍𝒍 𝒍𝒊𝒏𝒌 𝒊𝒏 𝒕𝒉𝒆 𝒄𝒐𝒎𝒎𝒆𝒏𝒕𝒔.

07/08/2025

Identical, or monozygotic, twins form when one fertilized egg divides into two embryos. In natural conception this is rare, happening in about 0.4% of pregnancies, but the rate is higher in IVF and ranges from 0.72% to 5%.

A recent review by Hongbin Jin and colleagues outlined the cellular mechanisms behind embryo splitting in IVF and how it can lead to identical twins.

Studies have shown that transferring blastocysts leads to higher rates of twins compared to earlier-stage embryos, suggesting that the blastocyst stage is a key point when embryos are vulnerable to splitting.

It’s now well accepted that if the ICM — the group of cells that will become the fetus — splits during the blastocyst stage or just after implantation, it can lead to monochorionic twins, meaning twins that share a single placenta.

So what causes the ICM to split and form twins? It seems to be influenced by how tightly the ICM cells stick together, the pressures from blastocyst expansion or cavitation, or the way the embryo hatches.

As the embryo hatches from the zona, sometimes it can happen in a way that creates a narrow opening. If part of the ICM is near this opening, it may get pulled through, creating an “8-shape” with cells on both sides. This can physically divide the ICM into two or more parts, potentially leading to twins.

Embryo splitting can occur at different stages, from before day 3 to after hatching.

Embryologists can reduce the risk of embryo splitting by closely monitoring development with time-lapse imaging and avoiding assisted hatching near the ICM.

✅ Check out all the details on Remembryo, link is in the comments.

✉️ Like this post? Explore more topics and sign up for my free Friday newsletter to stay updated on the latest IVF research (link in the comments).

𝐇𝐚𝐯𝐞 𝐚𝐧𝐲 𝐨𝐟 𝐲𝐨𝐮𝐫 𝐬𝐢𝐧𝐠𝐥𝐞 𝐞𝐦𝐛𝐫𝐲𝐨 𝐭𝐫𝐚𝐧𝐬𝐟𝐞𝐫𝐬 𝐫𝐞𝐬𝐮𝐥𝐭𝐞𝐝 𝐢𝐧 𝐚 𝐭𝐰𝐢𝐧 𝐩𝐫𝐞𝐠𝐧𝐚𝐧𝐜𝐲? 𝑵𝒐𝒕𝒆 𝒕𝒉𝒂𝒕 𝒕𝒉𝒊𝒔 𝒑𝒐𝒔𝒕 𝒊𝒔 𝒇𝒓𝒐𝒎 𝒎𝒚 𝒑𝒖𝒃𝒍𝒊𝒄-𝒇𝒂𝒄𝒊𝒏𝒈 𝒑𝒂𝒈𝒆. 𝑻𝒉𝒆 𝒔𝒂𝒎𝒆 𝒑𝒐𝒔𝒕 𝒄𝒂𝒏 𝒃𝒆 𝒇𝒐𝒖𝒏𝒅 𝒊𝒏 𝒎𝒚 𝒑𝒓𝒊𝒗𝒂𝒕𝒆 𝒈𝒓𝒐𝒖𝒑, 𝒘𝒉𝒊𝒄𝒉 𝑰'𝒍𝒍 𝒍𝒊𝒏𝒌 𝒊𝒏 𝒕𝒉𝒆 𝒄𝒐𝒎𝒎𝒆𝒏𝒕𝒔.

06/08/2025

The Uterine Wall of Fame (UWOF) is a collection of real IVF success stories from people who faced tough odds -- low-grade embryos, repeated failures, low AMH, mosaic results, and more.

UWOF #15 is one of those stories!

After 10 egg retrievals, 17 transfers, six losses, and many failed cycles, this IVF patient finally brought home her miracle boy when her last frozen embryo, the worst graded and untested, succeeded with the help of immune treatments and persistence.

✅ Visit the UWOF to read this full story and others like it (link in the comments, free to access & no subscription required).

💌 Have a story of your own? Can be anonymous or named -- link to the form is in the comments.

⚠️ The UWOF is a project by Remembryo / Embryoman, created to give hope to others going through IVF with challenging situations. These stories are personal, not medical advice. What works for one may not work for all—always check with your doctor before making treatment changes.

𝑵𝒐𝒕𝒆 𝒕𝒉𝒂𝒕 𝒕𝒉𝒊𝒔 𝒑𝒐𝒔𝒕 𝒊𝒔 𝒇𝒓𝒐𝒎 𝒎𝒚 𝒑𝒖𝒃𝒍𝒊𝒄-𝒇𝒂𝒄𝒊𝒏𝒈 𝒑𝒂𝒈𝒆. 𝑻𝒉𝒆 𝒔𝒂𝒎𝒆 𝒑𝒐𝒔𝒕 𝒄𝒂𝒏 𝒃𝒆 𝒇𝒐𝒖𝒏𝒅 𝒊𝒏 𝒎𝒚 𝒑𝒓𝒊𝒗𝒂𝒕𝒆 𝒈𝒓𝒐𝒖𝒑, 𝒘𝒉𝒊𝒄𝒉 𝑰'𝒍𝒍 𝒍𝒊𝒏𝒌 𝒊𝒏 𝒕𝒉𝒆 𝒄𝒐𝒎𝒎𝒆𝒏𝒕𝒔.

05/08/2025

July's IVF Research Roundup is live!

🔹 New study highlights
🔹 IVF news & community Q&A
🔹 70 research study summaries (subscribers only)

📌 Post is free to read — link in the comments.

04/08/2025

Trump promised during his campaign to make insurance cover IVF or have the government pay for it, but so far his administration has not taken any steps to expand access, and insiders say there are no current plans to require coverage under the Affordable Care Act, according to reporting by The Washington Post.

During his 2024 campaign, Trump said, "The government is going to pay for it, or we’re going to get — we’ll mandate your insurance company to pay for it, which is going to be great. We’re going to do that."

A senior administration official told The Washington Post that IVF expansion is a priority for Trump, but making it an essential health benefit would require a bill from Congress, and it is unclear if the White House will ask lawmakers to do that.

Even if the ACA were required to cover IVF, it would only reach about 50 million people, which is less than 20% of Americans, though some families could buy a marketplace plan as secondary coverage.

Forcing ACA plans to cover IVF could also raise premiums by several percentage points for everyone and hurt Republicans before the 2026 midterms, and one person familiar with the talks said, “It appears for now that they’re not going to go there.”

Instead, the White House has been asking advisers about restorative reproductive medicine (RRM), a fertility approach tied to Catholic teachings and promoted by the Heritage Foundation, but critics say it falls far short of Trump’s pledge and could delay effective treatment.

✅ Check out all the details on The Washington Post, link is in the comments.

✉️ Like this post? Explore more topics and sign up for my free Friday newsletter to stay updated on the latest IVF research (link in the comments).

𝑵𝒐𝒕𝒆 𝒕𝒉𝒂𝒕 𝒕𝒉𝒊𝒔 𝒑𝒐𝒔𝒕 𝒊𝒔 𝒇𝒓𝒐𝒎 𝒎𝒚 𝒑𝒖𝒃𝒍𝒊𝒄-𝒇𝒂𝒄𝒊𝒏𝒈 𝒑𝒂𝒈𝒆. 𝑻𝒉𝒆 𝒔𝒂𝒎𝒆 𝒑𝒐𝒔𝒕 𝒄𝒂𝒏 𝒃𝒆 𝒇𝒐𝒖𝒏𝒅 𝒊𝒏 𝒎𝒚 𝒑𝒓𝒊𝒗𝒂𝒕𝒆 𝒈𝒓𝒐𝒖𝒑, 𝒘𝒉𝒊𝒄𝒉 𝑰'𝒍𝒍 𝒍𝒊𝒏𝒌 𝒊𝒏 𝒕𝒉𝒆 𝒄𝒐𝒎𝒎𝒆𝒏𝒕𝒔.

04/08/2025

(Advertisement by IVF Media Ltd.)

Check out the IVF Abroad - Patient's Guide 2025, showcasing the best countries for IVF treatment abroad! With this guide you can check clinic popularity, success rates, IVF treatment costs and legislation. The guide is comprehensive and includes 105 pages with 11 of the most popular countries, without ads.

Link in the comments.

04/08/2025

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