Neural Regeneration Research

08/07/2025

hGCase-1/17 and hGCase-1/23 are antibodies for studying GCase in lysosomes and beyond. Perfect for immunofluorescence, co-immunoprecipitation, and AlphaLISA assays! Learn how they’re advancing GBA1-linked PD research: https://journals.lww.com/nrronline/fulltext/2025/04000/new_glucocerebrosidase_antibodies_can_advance.19.aspx

An abstract is unavailable.

08/07/2025

Public awareness of neurodegenerative diseases in Saudi Arabia is limited, with most people recognizing only motor symptoms like tremors. Non-motor symptoms, such as loss of smell, are often overlooked. Education campaigns could bridge this gap. Dive into Saudi PD research here:
https://journals.lww.com/aa/fulltext/2025/09000/awareness_level_and_management_plans_for_tackling.3.aspx

. This article incorporates the work carried out by Saudi researchers to evaluate the knowledge and awareness about Alzheimer’s disease and Parkinson’s disease in their elderly population to provide innovative care concepts for such patients. It also mentions the application of machine learning ...

07/07/2025

🦸‍♂️💨 Say hello to mineral drugs' surprising superpower—releasing gasotransmitters! These tiny gas molecules are proving to be mighty fighters against inflammation and diseases. With the boost of nanotechnology, they're enhancing drug delivery and reducing side effects. Link to article: https://journals.lww.com/mgar/fulltext/2025/03000/new_approach_of_modern_pharmacology__from.23.aspx

An abstract is unavailable.

07/07/2025

✨ Astrocytes play a crucial role in brain health and disease. A new study reveals how effectively extracting polyribosomes from these cells helps uncover their gene expression strategies. This discovery could lead to innovative treatments for neurological disorders. Link to article: https://journals.lww.com/nrronline/fulltext/2025/04000/effective_extraction_of_polyribosomes_from.18.aspx

An abstract is unavailable.

04/07/2025

The success of neuroprotective treatments hinges on just the right dose and timing. Discover how mitochondria can be both the problem and the solution. Link:

An abstract is unavailable.

04/07/2025

💪 How's this for innovation? Grip strength tests combined with AI can now help identify Parkinson's disease. The study reveals a potential game-changer in neurodegenerative diagnostics with impressive accuracy rates. https://www.sciencedirect.com/science/article/pii/S2950588725000710

03/07/2025

⚙️ How does the embryonic brain organize itself? Key insights: The cortical hem acts as a vital signaling center, secreting molecules like Wnts/BMPs to orchestrate cortical patterning & hippocampal formation. Deep dive into the mechanisms:
https://journals.lww.com/nrronline/fulltext/2025/04000/cortical_hem_signaling_center__functions,.16.aspx

An abstract is unavailable.

03/07/2025

Exciting updates on intravenous mesenchymal ! This meta-analysis explores its safety across 36 randomized controlled trials. Few significant adverse effects found, with most adverse events manageable. However, increased risk of infections detected.
https://journals.lww.com/rmr/fulltext/2025/09000/safety_of_intravenous_mesenchymal_stem_cell.1.aspx

em cells administered intravenously. We explored PubMed, ScienceDirect, Web of Science, ClinicalTrials.gov, and the Cochrane Library for published research from their creation through December 2024, following PRISMA 2020 guidelines. Two researchers independently assessed the study’s inclusion and ...

02/07/2025

A study explores the apoptosis signal-regulating kinase 1 mechanism in glial cells and its impact on diseases like multiple sclerosis. The results show that targeting apoptosis signal-regulating kinase 1 in microglia and astrocytes could be a potential treatment strategy. Learn more:
https://journals.lww.com/nrronline/fulltext/2025/04000/asking_one_mechanism_in_glial_cells_during.15.aspx

An abstract is unavailable.

02/07/2025

Did you know neurotoxicity is a major cause of drug withdrawal? Scientists have developed a groundbreaking model using molecular fingerprints and machine learning to predict neurotoxicity with high accuracy. This is a big step towards safer medications. Learn how here: https://journals.lww.com/atn/fulltext/2025/09000/integrating_molecular_fingerprints_with_machine.2.aspx

JOURNAL/atin/04.03/02274269-202509000-00002/figure1/v/2025-05-23T114004Z/r/image-tiff

01/07/2025

Fascinating new study in Neural Regeneration Research explores how metabolic dysfunction from obesity impacts the liver - brain axis, triggering neuroinflammation and contributing to neurodegenerative diseases like Alzheimer’s and Parkinson’s. A must - read for understanding this complex link: https://journals.lww.com/nrronline/fulltext/2025/04000/role_of_metabolic_dysfunction_and_inflammation.14.aspx

heral lipid accumulation, particularly in the liver, initiates a cascade of inflammatory processes that extend to the brain, influencing critical metabolic regulatory regions. Ceramide and palmitate, key lipid components, along with lipid transporters lipocalin-2 and apolipoprotein E, contribute to....

01/07/2025

A recent meta-analysis published in Aging Advances reveals that dual antiplatelet therapy is more effective than aspirin alone in reducing ischemic stroke recurrence and improving functional outcomes in patients with minor strokes or transient ischemic attacks. Read the study:
https://journals.lww.com/aa/fulltext/2025/09000/optimization_and_individualization_of_dual.2.aspx

erienced a transient ischemic attack or an ischemic stroke, we sought to identify the benefits and risks of each intervention to provide healthcare provider with objective evidence for use in construct comprehensive treatment plans. We conducted a systematic review and meta-analysis to assess dual a...