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Pain Medicine News A publication for the clinician interested in the diagnosis, treatment and management of pain.

Pain Medicine News, the most widely read pain publication in the United States according to Kantar Media, is mailed to 41,828 pain-treating physicians and to 41,152 pain-treating nurse practitioners and physician assistants. It offers extensive coverage of major scientific meetings affecting the specialty, feature articles on topics relevant to practicing provider, in-depth clinical reviews, practice management articles, medical education, as well as a full line of digital media, including the PainMedicineNews.com website, e-Newsletters, and multimedia content.

05/09/2026

🩸 PRP has traditionally started with a blood draw. What if it started in the bone instead?

A new pilot study is taking a closer look at intraosseous-derived PRP, asking whether the source of the biologic material could influence its regenerative properties.

Early findings from paired samples suggest differences in VEGF, IL-10, TGF-beta, SDF-1 and other signaling molecules compared with conventional peripheral-blood PRP.

But there’s an important caveat: this was a five-patient characterization study with no clinical outcomes.

Could this be a new direction for orthobiologics?

👉 Read the full story to explore the science behind the approach: https://www.painmedicinenews.com/a/NT0BAA/f

05/09/2026

For decades, the prevailing narrative in hernia surgery has been straightforward: A patient presents with a ventral hernia, undergoes repair, and goes home cured.

https://www.painmedicinenews.com/a/Dj4BAA/f

👶💤 Pediatric sedation is both an art and a science. The right approach goes beyond medication—it requires understanding ...
02/09/2026

👶💤 Pediatric sedation is both an art and a science. The right approach goes beyond medication—it requires understanding the child, the procedure, and the bedside manner needed to keep young patients safe and comfortable.

Dr. Kar-Mei Chan-Linder shares how anesthesiologists can find the “just right” balance: https://www.painmedicinenews.com/a/uj0BAA/f

New research suggests IV ketamine may offer short-term pain relief for some people with complex regional pain syndrome (...
02/09/2026

New research suggests IV ketamine may offer short-term pain relief for some people with complex regional pain syndrome (CRPS). A review of 21 studies involving 605 patients found meaningful early pain reduction, but benefits appeared to fade over time—and evidence remains limited on who is most likely to respond.

More standardized research is needed before treatment can be reliably personalized. Read more: https://www.painmedicinenews.com/a/3z0BAA/f

Could a hospital-wide pain strategy improve recovery while reducing opioid use? 🏥A study of 3,658 adults undergoing appe...
01/09/2026

Could a hospital-wide pain strategy improve recovery while reducing opioid use? 🏥

A study of 3,658 adults undergoing appendectomy or cholecystectomy found that full implementation of multimodal analgesia was associated with:

âś… Nonopioid analgesic use rising from 40.1% to 73.6%
âś… Opioid use falling from 80.2% to 74.5%
âś… Lower inflammatory marker levels
âś… A trend toward shorter hospital stays
âś… No increase in complication rates

Pain scores rose slightly, which researchers attributed to improved pain reporting. More rigorous studies are needed before broader adoption.

Read more: https://www.painmedicinenews.com/a/zj0BAA/f

01/09/2026

New research shows a redesigned PNS lead significantly reduced complication rates—but experts say it’s not quite where it needs to be yet.

Lead retention dropped from 13.4% to 3.1%, marking real progress in patient safety. Still, many clinicians believe rates should be even lower.

đź”— https://www.painmedicinenews.com/a/TDkBAA/f

01/09/2026

What causes pain in diabetic neuropathy?

It may not be what we think.

New research shows that having pain in multiple areas of the body—not just nerve damage—may be one of the strongest predictors of painful diabetic neuropathy.

đź”— https://www.painmedicinenews.com/a/UzkBAA/f

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