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The first independent media outlet to focus specifically on genetic counseling.

19/12/2024

Surprise: Our Most Popular Show of 2024 Was on Genomic AI

This year in a series co-produced with GenomeWeb we had an exclusive look into Illumina’s work in genomic AI with Kyle Farh, the VP and Distinguished Scientist leading the Illumina Artificial Intelligence Lab.

14/11/2024

Renowned GI Oncologist Dr. Mark Lewis Discusses MRD Testing and the Future of Cancer Detection

Intermountain Health

In this episode, Dr. Lewis joins Theral in our ongoing series on minimal residual disease (MRD) testing, a revolutionary blood test that is helping detect residual cancer causing a paradigm shift in patient management.

12/11/2024

Precision Medicine Then and Now:

We Talk with the Retiring President of the Personalized Medicine Coalition, Ed Abrahams

When Bill Clinton announced the sequencing of the human genome in 2000, the New York Times ran the following headline on the front page: "Genetic Code of Human Life is Cracked By Scientists.”We’re still living up to that headline.

31/10/2024

Somatic Genomics: A Revolution in Biology with Jacob Rubens

"The somatic genome is a revolutionary alternative view of what is going on in every cell. All 30 trillion cells in our bodies have a distinct sequence of DNA. Two cells sitting next to each other may differ by thousands of base pairs.”

Jacob Rubens is having quite a career. Studying at MIT in the Synthetic Biology Center with Professor Tim Lu, he invented gene circuits that allow engineered cells to do novel analog, digital, and hybrid computations, enabling the emerging field of “intelligent” cell therapies. In 2017, he was h...

30/10/2024

Exploring the Future of Single Cell Technology
with , CEO of Single Cell Discoveries

Human genomics is complex. With new, scalable tools, we are unraveling that complexity. For example, we don’t just each have one genome; we have trillions, as each cell has a unique genome. Analyzing biology at the single-cell level continues to be one of the major frontiers in research.To learn h...

26/09/2024

As Sequencing Continues to Scale, Volta Labs Improves Sample Prep:
We talk with CEO Udayan Umapathi

https://mendelspod.com/p/as-sequencing-continues-to-scale?r=bqr7&utm_campaign=post&utm_medium=web

Depending on your age, DNA sequencing is experiencing a second or third renaissance. New sequencing tools continue to make genomics one of the fastest-growing industries of all time. All this scaling can create a bottleneck in sample prep. Volta Labs, a company founded out of the MIT Media Lab by Ud...

19/09/2024

What’s Next for Large-Scale ?

Chris Whelan is a director of neuroscience on the data science and digital health team at Janssen Research & Development. He’s also chair and co-founder of the Pharma Proteomics Project.

Genetic studies of human populations have become a major tool for drug development. In the last few years, these studies have moved toward comprehensive proteomics profiling as well. In late 2023, a paper was published in Nature by the Pharma Proteomics Project, which characterized the plasma proteo...

17/09/2024

Will this At-Home Blood Collection Device Transform Medicine?

We talk with Ben Casavant, CEO

https://www.mendelspod.com/p/will-this-at-home-blood-collection?r=bqr7&utm_campaign=post&utm_medium=web

A new blood collection device offered by startup company Tasso is a blood lancet that collects whole liquid blood samples. Its ease of use for at-home collection could dramatically improve patient testing compliance and impact the scale of clinical trials.Ben Casavant is the co-founder and CEO of Ta...

12/09/2024

Geneticist Kevin Mitchell Attempts to Naturalize Free Will in New Book

What are the broad implications of free will for further study of biology and philosophy? How might his thinking extend to robots and AI?

https://www.mendelspod.com/p/geneticist-kevin-mitchell-attempts?r=bqr7&utm_campaign=post&utm_medium=web

Today, we continue “The New Biology” series with a non-reductive geneticist from Trinity College in Dublin. Kevin Mitchell is the author of Free Agents: How Evolution Gave Us Free Will.The problem of free will has dogged philosophers and scientists as much as any question going back to the Greek...

22/08/2024

14th Season Opener:

Michael Levin on ‘The New Biology’

"The idea is to go in and “reprogram” the goals of a group of cells and let them do the work of reversing disease."

For over a hundred years, biologists have been working to fully understand biology at the level of chemistry, in other words unite biology with chemistry. This is considered the reductive approach inspired by the unification of chemistry with physics in the early 20th century with the Periodic Table...

03/05/2024

This week, the FDA published its long-awaited rules for LDTs
The final rule mandates that all IVDs, including those developed in laboratories such as genetic tests, comply with the same FDA requirements as other medical devices.

The FDA says it will phase out its policy of enforcement discretion for LDTs in five stages over the next four years.

It’s a red-letter day for the genetic testing industry. We all said we’ll believe it when we see it. Well, we can now see it. This week, the FDA published its long-awaited rules for LDTs. After decades of exercising “enforcement discretion” and waving flags about using enforcement, they have...

16/01/2024

Quality Healthcare Should Not Depend on Which Book Club You Attend:
Listen to Karen Tumulty of the Washington Post

Karen Tumulty, a political writer for the Washington Post, was diagnosed with multiple myeloma. She was told she had five years to live. Then she went to book club with friends and came out about her diagnosis—that changed her life. Someone in attendance happened to be the President of the Persona...

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