Clinical Pain Advisor

30/09/2026

Loved our coverage of ? Catch all 5 of our top-performing clinical posts in one September roundup.

🦵 Thigh Pain 2 Years After Hip Replacement Surgery:
https://bit.ly/4ynJOg8

🧪 Kratom Provides Substantial Relief in Patients With Chronic Pain:
https://bit.ly/4z2dK19
With the United States Association for the Study of Pain's The Journal of Pain.

💊 Illicit Stimulant Use Common for Chronic Pain Management in Women With Neuropathic Pain:
https://bit.ly/4dd10MR

💢 Low Back Pain Usually Co-Occurs With Neck, Shoulder, Hip, and/or Thigh Pain:
https://bit.ly/4z02xxX
With International Association for the Study of Pain (IASP) PAIN The Journal.

⚽ Acute Pain Management Among Elite Athletes – Insights From Sports Specialists:
https://bit.ly/4qM3x6d
With Anthony Breitbach, PhD of Doisy College of Health Sciences at Saint Louis University and Saint Louis University.

21/09/2026

An abbreviated 7-item questionnaire accurately measures movement-related fear in children and adolescents with chronic pain, reducing respondent burden without compromising clinical utility.

cc: International Association for the Study of Pain (IASP)

Read more:

The abbreviated 7-item Tampa Scale of Kinesiophobia for Youth is a valid tool for assessing fear of movement in pediatric patients with chronic pain.

17/09/2026

Subjective thermal pain correlates most strongly with autonomic responses when researchers utilize an automated trough-to-peak sum of amplitudes following the manual exclusion of artifact trials.

cc: International Association for the Study of Pain (IASP)

Combining manual artifact detection with automated trough-to-peak amplitude scoring optimizes skin conductance measurement of thermal pain.

17/09/2026

Social determinants of health, particularly perceived discrimination, significantly increase the likelihood of patients on maintenance hemodialysis experiencing severe physical and psychological symptom clusters.

Patients with end-stage kidney disease on hemodialysis who experience perceived discrimination have a higher burden of pain and anxiety.

15/09/2026

Preoperative exposure and younger age are among risk factors associated with an increased risk for prolonged postoperative opioid consumption in patients treated for head and neck adenoid cystic .

Read more:

Many patients undergoing curative surgery for head and neck adenoid cystic carcinoma continue using prescription opioids months after the procedure.

15/09/2026

As highlights the need for non-opioid therapeutic options, targeted peripheral analgesics continue to gain interest among clinicians and researchers.

Recent Phase 3 clinical trial evaluations of , a highly selective NaV1.8 voltage-gated sodium channel inhibitor, demonstrate statistically significant reductions in acute postoperative pain compared to placebo:

📊 Abdominoplasty Trial: Least squares mean difference (LSMD) in SPID48 of 48.4 (95% CI: 33.6–63.1; P < .0001).

📊 Bunionectomy Trial: LSMD in SPID48 of 29.3 (95% CI: 14.0–44.6; P = .0002).

Selective inhibition of peripheral NaV1.8 channels blocks signal transmission at the primary sensory neuron without central nervous system sedation or respiratory depression.

Read the full clinical review and analysis for evidence-based practice here: ➡️https://bit.ly/4gtTE9H

14/09/2026

The integration of warming-dredging into standard treatment protocols significantly decreases pain severity and lowers the need for analgesics among patients experiencing cancer-related pain.

Cc: Frontiers

Warming-dredging acupuncture combined with routine care significantly decreases pain intensity in patients with cancer-related pain.

10/09/2026

Interventions that target the functional and cognitive-emotional aspects of pain can offer meaningful benefits for patients with chronic pain and poor sleep.

cc: United States Association for the Study of Pain

Skills-based behavioral interventions improve sleep quality in adults with chronic low back pain by decreasing pain catastrophizing and interference.

09/09/2026

Nonrigid lumbar belts are a nonpharmacologic treatment option to add to usual care of nonspecific , researchers published in JAMA Network Open.

Read more: https://www.clinicalpainadvisor.com/news/nonrigid-lumbar-belts-low-back-pain/

08/09/2026

For , this resource focuses on , a primary contributor to chronic axial spinal pain and radiculopathy. Driven by the natural wear and tear of intervertebral discs over time, DDD occurs as discs lose hydration and structural height. The resulting decline in shock absorption leads to localized stiffness, nerve compression, and secondary musculoskeletal conditions, including spinal osteoarthritis.

🧪 Key Takeaways for Practice & Patient Education:

➡️ Pathology: Annular tearing and structural disc breakdown produce localized inflammation and bone spur formation secondary to mechanical stress.

➡️ Symptom Presentation: Manifestations vary from localized back or neck stiffness to radiating pain, numbness, and motor weakness in the extremities.

➡️ Management Continuum: Initial management relies on conservative therapies, including physical therapy, anti-inflammatory pharmacotherapy, and activity modification. Interventional procedures or surgical evaluation are reserved for persistent functional impairment or neurologic compromise.

Access the complete clinical factsheet here: ➡️ https://bit.ly/4cPanlu