21/01/2021
AVOID TAKING NSAID PAIN RELIEVERS WHEN YOU ARE PREGNANT.
Taking ibuprofen(Brufen) , Aspirin, Diclofenac and other types of nonsteroidal anti-inflammatory drugs (NSAIDs) in the second half of pregnancy can lead to oligohydramnios (low amniotic fluid) or kidney problems in the baby.
NSAIDs block the production of prostaglandins in the body. These chemicals are responsible for pain or inflammation.
When taken during pregnancy, NSAIDs reduce blood flow to the baby's kidneys and other important structures. Reduced blood flow to the kidneys leads to reduced urine production by the fetus. Since amniotic fluid is really just the collection of fetal urine, oligohydramnios can develop. These drugs can trigger a reaction that closes an important cardiac blood vessel early, putting the fetus at risk.
Problems with the amniotic fluid or kidneys typically arise within days to weeks after NSAID treatment. However, amniotic fluid levels may decrease within 48 hours.
Complications of low amniotic fluid can include POOR LUNG DEVELOPMENT or LIMB CONTRACTURE, which means the limbs and joints are inflexible, if it happens early in pregnancy and isn’t reversible.
Low amniotic fluid often is reversible if the patient stops taking NSAIDs as soon as a problem is noticed. Rarely, babies born with kidney complications may require dialysis.
In some rare cases, Nsaids treatment may outweigh the risk in pregnancy. For example, Low dose Aspirin is prescribed to delay or prevent preeclampsia or in those with history of High blood pressure.
If you must take NSAIDs after 20 weeks, your doctor might recommend ultrasound monitoring to keep an eye on the amniotic fluid levels.
Always consult your pharmacist
NB: Pregnant Women do not take medications alone.
Your Caring Pharmacist.
