09/02/2025
Pe**te is a small, spineless cactus native to northern Mexico and the southwestern United States, known scientifically as Lophophora williamsii. It's prohibited in Mexico. The cactus grows to a height of 2 to 7 cm and a diameter of 4 to 12 cm, with the part above ground called the "corona." This corona consists of disk-shaped sections that contain mescaline, a psychoactive compound.
Pe**te flowers, which can be white, pink, slightly yellow, or reddish, bloom during the day and measure 1 to 2.4 cm in length and 1 to 2.2 cm in diameter. After flowering, small pink fruits appear, which turn brownish-white when dried. These fruits are fleshy and contain black, pear-shaped seeds that are about 1 to 1.5 mm long and 1 mm wide. Pe**te has a bitter taste.
The cactus thrives in limestone soils and thorny desert scrub at altitudes between 100 to 1,500 meters above sea level, which helps protect it from predators. Pe**te grows very slowly, taking over 30 years to mature and flower. Within its genus, L. williamsii has the highest concentration of mescaline.
Mescaline, a compound similar to dopamine, has psychedelic effects primarily due to its interaction with 5-HT2A and 5-HT2C receptors, though its affinity is lower than that of LSD-25. A psychoactive dose of mescaline is about 5 mg per kg of body weight, with each pe**te button containing around 45 mg. The effects begin about 30 minutes after oral ingestion, as mescaline is absorbed through the gastrointestinal tract. The oldest pe**te plants have the highest mescaline content, which varies from 0.7% to 3.5% by weight, depending on environmental conditions and soil quality