04/12/2025
Diphtheria is caused by the toxin released from the Corynebacterium diphtheriae bacteria. The most common form —respiratory diphtheria — affects the nose and throat, forming a thick gray coating. If left untreated, it can damage the heart, kidneys and nervous system, and can even lead to death. The most common way to spread diphtheria is through close contact with an infected person’s coughs and sneezes. A dependable vaccine was developed in the early 1920s to reduce pediatric deaths.
During World War II, the U.S. Army did not initially vaccinate soldiers for diphtheria, believing that the risk was low, due to prior immunity. However, cases quickly rose in the South Pacific, North Africa, and Europe. In 1945, the U.S. Army began universal immunization against diphtheria, successfully eliminating the disease within the Armed Forces.
Image: This illustration shows the throat of a person with symptoms of diphtheria. In this rare case, the bacteria was transmitted by a cat and patient died. Artist, possibly E.C. Moncure, date unknown. OHA 229.27.12