Medical Sciences MDPI

25/11/2025

✨ Call for Papers! Our New Special Issue Is Now Open!

We are delighted to introduce the Medical Sciences Special Issue: “Endovascular Management of Complex Aortic Pathologies and Complications”, led by Guest Editor Dr. Mafalda Massara.

This issue welcomes impactful research on:

🔬 Innovative endovascular treatment strategies
🫀 Management of complex aortic conditions and related complications
🖥️ Advances in imaging, devices, and procedural planning
📊 Clinical outcomes, case reports, and multidisciplinary perspectives

📌 Submit your manuscript:
https://www.mdpi.com/journal/medsci/special_issues/85K28BIORL

Join us in advancing the future of endovascular care!

Special Issue in journal Medical Sciences: Endovascular Management of Complex Aortic Pathologies and Complications

25/11/2025

📣 Special Issue Now Open for Submissions!

We are excited to announce the launch of the Special Issue “Advances in Immune Tolerance Induction After Liver Transplantation” in Medical Sciences, guest-edited by Dr. Luit Penninga.

This issue welcomes cutting-edge research on:

- Mechanisms and strategies for immune tolerance induction
- Novel therapeutic approaches to improve liver transplant outcomes
- Translational studies bridging immunology and clinical practice
- Innovations in organ transplant immunomodulation

📌 Submit your manuscript here: https://www.mdpi.com/journal/medsci/special_issues/17D8HUY02L

Join us in advancing the frontiers of liver transplant immunology!

25/11/2025

New in Medical sciences!

📄 Outcomes in Acute Decompensated Congestive Heart Failure Admissions with Chronic Liver Disease: A Nationwide Analysis Using the National Inpatient Sample
👤 Vivek Joseph Varughese et al.

Read here: https://www.mdpi.com/2076-3271/13/1/19

The study found that ADHF (acute decompensated heart failure) admissions with a comorbid diagnosis of chronic liver disease (CLD) had significantly higher all-cause in-hospital mortality, longer hospital stays, and greater total hospital charges than those without CLD. After adjusting for confounders, the presence of CLD was significantly associated with mortality (OR 1.23, 95% CI 1.17–1.29). In propensity-matched cohorts, the CLD group still had a higher mortality rate than those without CLD.

AIM: The aim of our study was primarily to analyze hospital outcomes for acute decompensated heart failure (ADHF) admissions with a comorbid diagnosis of chronic liver disease (CLD). METHODS: The NIS was used to select ADHF admissions. The population characteristics of general ADHF admissions were c...

24/11/2025

🚀 New Special Issue Now Open for Submissions!

We are excited to announce the launch of our latest Special Issue in Medical Sciences: “Artificial Intelligence in Oncologic Imaging: Advances in Medical Image Segmentation and Predictive Modelling”.

Under the guidance of Guest Editors Dr. Orazio Gambino and Dr. Salvatore Contino, this issue focuses on cutting-edge research exploring AI applications in oncologic imaging, from enhanced image segmentation to predictive modeling for improved patient outcomes.

📌 Learn more here: https://www.mdpi.com/journal/medsci/special_issues/904E6D5140

Join us in advancing AI-driven solutions in oncology!

24/11/2025

✨ New in Medical Sciences!
📝 The Success and Safety of Endoscopic Retrograde Cholangiopancreatography in Surgically Altered Gastrointestinal Anatomy
👤 Samuel Han et al.

This large, single‑center retrospective study (334 patients, 665 ERCPs) found that ERCP using forward‑viewing endoscopes in altered GI anatomy is both safe and effective, with an overall adverse event rate of just ~5%. Enteroscopy success ranged from 82% to 97% depending on anatomy type (e.g., Roux‑en‑Y, Billroth II).

🔗 https://www.mdpi.com/2076-3271/13/1/18

Background/Objectives: Performing endoscopic retrograde cholangiopancreatography (ERCP) in surgically altered gastrointestinal anatomy remains challenging, frequently necessitating the use of forward-viewing endoscopes. Given the challenge in endoscope selection based on the type of altered anatomy,...

21/11/2025

Published in Medical Sciences!

📄 “Rheumatoid Arthritis Prevalence and Risk Factors in Korean Adults: A Focus on Age and S*x Differences”
👤 Lee, D.-Y.

Using data from 25,166 Korean adults (KNHANES 2016–2021), this study found a 1.1% RA prevalence (0.6% in men vs. 1.7% in women), with rates rising with age to a peak of 3.5% in those over 70. Key risk factors included education level, subjective health status, and age, highlighting the need for tailored, s*x- and age‑specific interventions.

🔗 https://www.mdpi.com/2076-3271/13/1/17

*xDifferences

20/11/2025

💊 Published in Medical Sciences!

📄 “Radiological and Clinical Outcome Differences Between Standard and Short Stem in Reverse Total Shoulder Arthroplasty: A Systematic Review”
👤 Ciuffreda, M. et al.

This review of 13 studies (1,485 shoulders) found worse radiological outcomes (loosening, lucencies, osteolysis) with short stems, but no significant difference in pain, function scores or complications compared to standard stems — both remain valid cementless options.

🔗 https://www.mdpi.com/2076-3271/13/1/16

Background: In recent years, the use of short cementless humeral components in reverse total shoulder arthroplasty (RTSA) has increased. This systematic review aimed to compare the radiological and clinical outcomes of uncemented RTSA using short versus standard humeral stems and assess the impact o...

19/11/2025

💊 Read in Medical Sciences!

📄 “A Scoping Review on Cognition in Myelodysplastic Syndromes: Advances and Challenges”
👤 Tsiakiri, A. et al.

This review of 25 studies (493 MDS patients) reveals frequent impairments in attention, memory & executive function in MDS, driven by systemic inflammation, treatment-related neurotoxicity, and aging—and calls for routine cognitive assessment and targeted interventions.

🔗 https://www.mdpi.com/2076-3271/13/1/15

Background/Objectives: Myelodysplastic syndromes (MDS) are clonal hematopoietic disorders characterized by ineffective hematopoiesis and a risk of progression to acute myeloid leukemia (AML). Cognitive impairments, including deficits in memory, attention, and executive function, are frequently repor...

18/11/2025

💊 Published in Medical Sciences!

📄 “Acute Hepatic Porphyria Should Be Included in the Diagnostic Work‑Up of Patients with Resistant Hypertension or Suspected Secondary Hypertension”
👤 de Lima Serrano, P. et al.

This paper argues that Acute Hepatic Porphyria (AHP) — a rare inherited metabolic disorder — is under-recognized in patients with resistant or secondary hypertension. The authors highlight that hypertension in AHP may result from dysautonomia during acute attacks or emerge as a chronic complication, and call for routine AHP screening in these patients because it’s potentially treatable.

🔗 https://www.mdpi.com/2076-3271/13/1/14

Secondary hypertension and resistant hypertension may result from potentially treatable acquired or hereditary diseases. Inherited Metabolic Disorders are not routinely included in the differential diagnosis of these contexts associated with hypertension, despite the key importance of diagnosis for....

17/11/2025

💊 Published in Medical Sciences!

📄 “Update on the Complications and Management of Liver Cirrhosis”
👤 Fadlallah, H. et al.

This review outlines the major complications of liver cirrhosis — from ascites and hepatic encephalopathy to variceal bleeding and hepatocellular carcinoma — and presents current evidence‑based management strategies. It emphasises early detection, individualized therapy, lifestyle modification, and multidisciplinary care to improve patient outcomes.

🔗 https://www.mdpi.com/2076-3271/13/1/13

14/11/2025

📣 Call for Papers!

We are now accepting submissions for the special issue “Artificial Intelligence (AI) in Cardiovascular Medicine” in the Medical Sciences journal.

This special issue invites cutting-edge research on AI applications in cardiovascular diagnostics, treatment planning, predictive modelling, imaging analysis, and personalized care. We encourage original studies, reviews, and short communications that explore how AI is transforming cardiovascular health.

🔗 Submit your manuscript or learn more: https://www.mdpi.com/journal/medsci/special_issues/H0YH4VH39X

12/11/2025

💡 Published in Medical Sciences!

📄 “An Unusual Case of Uremic Tumoral Calcinosis with Atypical Manifestation in a Patient on Peritoneal Dialysis”
👤 Moral Berrio, E. et al.

This case report describes a 34‑year‑old woman on peritoneal dialysis who developed a calcified soft tissue mass in the proximal phalanx of her third finger—an unusual location for Uremic Tumoral Calcinosis (UTC). It highlights how persistent hyperphosphataemia and secondary hyperparathyroidism can trigger UTC and shows that by switching to automated dialysis and intensifying phosphate management, complete remission was achieved.

🔗 https://www.mdpi.com/2076-3271/13/1/11

Background: Uremic tumoral calcinosis (UTC) is a rare yet severe complication of chronic kidney disease (CKD), predominantly occurring in patients undergoing renal replacement therapy (RRT). It is characterized by extensive soft tissue calcifications, frequently associated with chronic hyperphosphat...