Bioengineering MDPI

15/12/2025

🌿 Advancing Skin Therapy with “Silymarin PlantCrystals for Improved Dermal Drug Delivery”

🥼 Authored by Tehseen Sehra, Muzn Alkhaldi, and Cornelia Keck

🔬 This study demonstrates how PlantCrystals derived from milk thistle seeds enhance the dermal pe*******on of lipophilic and poorly soluble active ingredients. Using an ex vivo porcine skin model, the formulation achieved up to a 90% increase in pe*******on for lipophilic compounds and significantly improved skin hydration.

✨ These findings highlight PlantCrystals as a promising nanocarrier system for next-generation topical drug delivery.

📖 Access the full article for free here 👉 https://www.mdpi.com/2306-5354/12/12/1331

Do not miss it! 🌼

Background/Objectives: PlantCrystals (PCs) are submicron particles derived from plants or parts of plants that can be produced by bead milling and/or high-pressure homogenization. Previous studies suggested improved dermal drug delivery of lipophilic active ingredients (API), which was explained by....

15/12/2025

🎉 We are delighted to share the second edition of the Bioengineering 2023 Editor’s Choice Articles, highlighting outstanding research and the brilliant minds driving innovation in bioengineering!

🔬 Prediction of Cognitive Load from Electroencephalography Signals Using a Long Short-Term Memory Network
🔗 https://www.mdpi.com/2306-5354/10/3/361

🔬 Connectivity Analysis in EEG Data: A Tutorial Review of the State of the Art and Emerging Trends
🔗 https://www.mdpi.com/2306-5354/10/3/372

🔬 Machine Learning for Brain MRI Data Harmonisation: A Systematic Review
🔗 https://www.mdpi.com/2306-5354/10/4/397

🔬 Fabrication of Hydrogel-Based Composite Fibers and Computer Simulation of Filler Dynamics in Composite Flow
🔗 https://www.mdpi.com/2306-5354/10/4/448

🔬 Human-Derived Cortical Neurospheroids Coupled with Passive, High-Density, and 3D MEAs: A Valid Platform for Functional Testing
🔗 https://www.mdpi.com/2306-5354/10/4/449

🔬 Electrical Stimulation in Cartilage Tissue Engineering
🔗 https://www.mdpi.com/2306-5354/10/4/454

🔬 Establishment of a Surgical Difficulty Grading System and MRI-Based Artificial Intelligence for Stratifying Difficulty in Laparoscopic Re**al Surgery
🔗 https://www.mdpi.com/2306-5354/10/4/468

🔬 The Power of ECG in Semi-Automated Seizure Detection Combined with Two-Channel Behind-the-Ear EEG
🔗 https://www.mdpi.com/2306-5354/10/4/491

🔬 Co-Electrospun Poly(ε-Caprolactone)/Zein Articular Cartilage Scaffolds
🔗 https://www.mdpi.com/2306-5354/10/7/771

🔬 Progressive Rehabilitation Based on EMG Gesture Classification and an MPC-Driven Exoskeleton
🔗 https://www.mdpi.com/2306-5354/10/7/770

📱 The publications can also be accessed via the QR codes below.

12/12/2025

🌟 Proud to present the 3rd Edition of the Bioengineering MDPI 2023 Editor's Choice Articles, featuring cutting-edge research that is shaping the future of bioengineering!

🔬 Model-Based Characterization of E. coli Strains with Impaired Glucose Uptake
🔗 https://www.mdpi.com/2306-5354/10/7/808

🔬 Cancer Drug Delivery Systems Using Bacterial Toxin Translocation Mechanisms
🔗 https://www.mdpi.com/2306-5354/10/7/813

🔬 Muscular and Kinematic Responses to Unexpected Translational Balance Perturbation: A Pilot Study in Healthy Young Adults
🔗 https://www.mdpi.com/2306-5354/10/7/831

🔬 Hydrogel-Impregnated Self-Oxygenating Electrospun Scaffolds for Bone Tissue Engineering
🔗 https://www.mdpi.com/2306-5354/10/7/854

🔬 Microbial PolyHydroxyAlkanoate (PHA) Biopolymers — Intrinsically Natural
🔗 https://www.mdpi.com/2306-5354/10/7/855

🔬 Biofunctionalized Decellularized Tissue-Engineered Heart Valve with Mesoporous Silica Nanoparticles for Controlled Release of VEGF and RunX2-siRNA Against Calcification
🔗 https://www.mdpi.com/2306-5354/10/7/859

🔬 Correlations Between Ratings and Technical Measurements in Hand-Intensive Work
🔗 https://www.mdpi.com/2306-5354/10/7/867

🔬 In Vivo Assessment of High-Strength and Corrosion-Controlled Magnesium-Based Bone Implants
🔗 https://www.mdpi.com/2306-5354/10/7/877

🔬 Recent Advancements in Deep Learning Using Whole Slide Imaging for Cancer Prognosis
🔗 https://www.mdpi.com/2306-5354/10/8/897

🔬 A Novel Non-Contact Detection and Identification Method for the Post-Disaster Compression State of Injured Individuals Using UWB Bio-Radar
🔗 https://www.mdpi.com/2306-5354/10/8/905

📱 All publications can also be accessed via the QR codes below.

10/12/2025

❤️ Can We Reprogram the Ischemic Heart?
A new study, “Intramyocardial Injection of Hypoxia-Conditioned Extracellular Vesicles,” shows how engineered vesicles may reshape redox signaling in severe coronary artery disease. 🔬💓

🐷 Using a swine model, researchers found that hypoxia-conditioned extracellular vesicles (HEVs) boost both antioxidant and pro-oxidant proteins, potentially fine-tuning redox balance to improve perfusion and reduce inflammation when no revascularization options remain.

🥼 Authored by Dwight D. Harris, Sharif A. Sabe, Mark Broadwin, Cynthia Xu, Christopher Stone, Meghamsh Kanuparthy, Akshay Malhotra, M. Ruhul Abid, and Frank W. Sellke.

📎 Read the full open-access article here: https://www.mdpi.com/2306-5354/11/2/125

Do not miss it! 🌸

Introduction: Patients with advanced coronary artery disease (CAD) who are not eligible for stenting or surgical bypass procedures have limited treatment options. Extracellular vesicles (EVs) have emerged as a potential therapeutic target for the treatment of advanced CAD. These EVs can be condition...

10/12/2025

✨ Discover the Future of Microsurgical Endodontics! ✨

Check out our Special Issue: “From Resorption to Regeneration: Innovation in Microsurgical Endodontics” 🦷💙

👨‍⚕️ Guest Edited by Dr. Mohammad A. Sabeti from The University of California

🔬 Modern microsurgical endodontics is shifting toward biologically driven, minimally invasive approaches, focused on tissue regeneration rather than mere resection.

🧬 With cutting-edge techniques such as bioceramic materials, guided tissue regeneration, and precision access, clinicians can now successfully manage:
✨ root resorption lesions
✨ apico-marginal communications
✨ complex defects requiring 3D tissue repair and engineering

👉 Learn more about the Special Issue here:
https://brnw.ch/21wYdAO

⏱ Submission deadline: June 25, 2026

📢 Join us as an author or reviewer! 🤝📚
Let’s shape the future of microsurgical endodontics together! 💡🦷🌱

Special Issue in journal Bioengineering: From Resorption to Regeneration: Innovation in Microsurgical Endodontics

09/12/2025

New publication alert in Bioengineering! 🌿
Title: Phytogenic Silver Nanoparticles Derived from Ricinus communis and Aloe barbadensis: Synthesis, Characterization, and Evaluation of Biomedical Potential

🥼 Authors: Anam Ahsan, George F. Gao, and Wen-Xia Tian

🔬 This study harnesses eco-friendly extracts from Ricinus communis and Aloe barbadensis to sustainably synthesize stable, uniformly spherical silver nanoparticles (15–28 nm). These phytogenic AgNPs exhibit strong antimicrobial, antioxidant, anti-inflammatory, and anticancer effects, presenting a versatile green nanoplatform for future biomedical and pharmaceutical applications.

📖 Open access article available here 👉 https://www.mdpi.com/2306-5354/12/11/1273

Check it out! 👩‍🔬

The green synthesis of silver nanoparticles (SNPs) using medicinal plants provides a sustainable and eco-friendly approach to nanoparticle production with promising biomedical potential.

08/12/2025

🎉 Bioengineering Spotlight | Interview with Prof. Dr. Kenneth Maiese

👨‍🔬 Meet Prof. Dr. Kenneth Maiese - the author of the highly cited article: “Cognitive Impairment in Multiple Sclerosis”, published in Bioengineering! 📚

📖 Read the full article here:
🔗 https://www.mdpi.com/2306-5354/10/7/871

👨‍🔬 Interested in the research process and the inspiration behind the study? Don’t miss our exclusive interview with Prof. Dr. Maiese!

📖 Full interview below:
🔗 https://www.mdpi.com/news/14085

08/12/2025

🌟 We are delighted to introduce Dr. Christian Demitri as Co-Session Chair for Session 3: Biosignal Processing at the 2nd International Conference on Bioengineering (BIOENG 2026)!

Dr. Demitri is an Associate Professor in Industrial Bioengineering, whose research spans biomaterials design, tissue engineering, and material–cell interactions. With 80+ scientific publications and strong international collaborations—including work with IFC-CNR and the University of Brighton—his research continues to drive impactful biomedical innovation.

✨ We are excited to have his leadership at BIOENG 2026!

🚀 Be part of this global event in Barcelona!
📝 Submit your abstract: https://sciforum.net/user/submission/create/1424

🎫 Register now and save with Early Bird rates: https://sciforum.net/event/BIOENG2026?section=

08/12/2025

📢 We are excited to introduce Dr. Egidio De Benedetto as Co-Session Chair for Session 3: Biosignal Processing at the 2nd International Conference on Bioengineering (BIOENG 2026)!

Dr. De Benedetto’s research spans key areas of biosignal analysis and biomedical engineering, driving advances in how biological data are collected, interpreted, and transformed into meaningful clinical and scientific applications.

📍 Join us in Barcelona, 11–13 November 2026 and be part of a global community of researchers exploring the latest breakthroughs in biosignal processing and the future of bioengineering.

🚀 Be part of this global event!
🔗 Learn more: https://sciforum.net/event/BIOENG2026

📝 Submit your abstract: https://sciforum.net/user/submission/create/1424

03/12/2025

✨ Introducing the First Edition of the Bioengineering MDPI 2023 Editor's Choice Articles!
Discover standout scientific advances and the brilliant minds behind them!

🔬 Unsupervised Learning-Based Non-Invasive Fetal ECG Multi-Level Signal Quality Assessment
🔗 https://www.mdpi.com/2306-5354/10/1/66

🔬 Attenuation of SCI-Induced Hypersensitivity by Intensive Locomotor Training and Recombinant GABAergic Cells
🔗 https://www.mdpi.com/2306-5354/10/1/84

🔬 Portable Iontophoresis Device for Efficient Drug Delivery
🔗 https://www.mdpi.com/2306-5354/10/1/88

🔬 A Two-Compartment Fermentation System to Quantify Strain-Specific Interactions in Microbial Co-Cultures
🔗 https://www.mdpi.com/2306-5354/10/1/103

🔬 Contactless Camera-Based Sleep Staging: The HealthBed Study
🔗 https://www.mdpi.com/2306-5354/10/1/109

🔬 Detection of Bacteria-Induced Early-Stage Dental Caries Using Three-Dimensional Mid-Infrared Thermophotonic Imaging
🔗 https://www.mdpi.com/2306-5354/10/1/112

🔬 Characterization of Perinatal Stem Cell Spheroids for the Development of a Cell Therapy Strategy
🔗 https://www.mdpi.com/2306-5354/10/2/189

🔬 Multilayer In Vitro Human Skin Tissue Platforms for Quantitative Burn Injury Investigation
🔗 https://www.mdpi.com/2306-5354/10/2/265

🔬 Exploring the Role of Visual Guidance in Motor Imagery-Based Brain-Computer Interfaces: An EEG Microstate-Specific Functional Connectivity Study
🔗 https://www.mdpi.com/2306-5354/10/3/281

🔬 Visual Blood: Visualisation of Blood Gas Analysis in Virtual Reality Improves Diagnostic Accuracy — A Computer-Based, Multicentre Simulation Study
🔗 https://www.mdpi.com/2306-5354/10/3/340

📱 The publications can also be accessed via the QR codes below!

02/12/2025

🩸 Rewiring renewal at the root: “Hematopoietic Stem Cell Aging: Mechanisms, Microenvironment Influences, and Rejuvenation Strategies” offers a comprehensive look at how aging disrupts blood and immune homeostasis, and what science is doing to reverse it.

🥼 Authored by: Jiaqi Cui, Xincan Li, Bin Liu, Cheng D**g, and Yun Chang from The Hong Kong Polytechnic University - PolyU

🔬 This review examines the mechanisms driving HSC aging, including intrinsic (genetic, epigenetic, metabolic) and extrinsic (inflammatory niche) factors. It highlights the critical role of the bone marrow microenvironment in shaping HSC function and aging. Cutting-edge pluripotent stem cell models and multi-omics approaches are helping decode the complexity of hematopoietic aging. The review also outlines emerging rejuvenation strategies and their clinical potential.

👉 Access the full article here: https://www.mdpi.com/2306-5354/12/11/1166

Don’t miss it! 🩺

Hematopoietic stem cells (HSCs) are essential for lifelong blood production and immune homeostasis. However, aging induces functional declines in HSCs, leading to hematological disorders, immune dysfunction, and increased susceptibility to malignancies. This review explores the biological underpinni...

01/12/2025

🌟 We are proud to present the 1st Edition of the Bioengineering 2023 Title Story Papers, showcasing cutting-edge research shaping the future of bioengineering.

🔬 Injectable Hydrogel Membrane for Guided Bone Regeneration
🔗 https://www.mdpi.com/2306-5354/10/1/94

🔬 Liver Ultrasound Histotripsy: Novel Analysis of the Histotripsy Site Cell Constituents with Implications for Histotripsy Application in Cell Transplantation and Cancer Therapy
🔗 https://www.mdpi.com/2306-5354/10/2/276

🔬 Planar Elliptical Inductor Design for Wireless Implantable Medical Devices
🔗 https://www.mdpi.com/2306-5354/10/2/151

🔬 Mn-Based Methacrylated Gellan Gum Hydrogels for MRI-Guided Cell Delivery and Imaging
🔗 https://www.mdpi.com/2306-5354/10/4/427

🔬 Hemodynamic Evaluation of a Centrifugal Left Atrial Decompression Pump for Heart Failure with Preserved Ejection Fraction
🔗 https://www.mdpi.com/2306-5354/10/3/366

🔬 Fabrication of Hydrogel-Based Composite Fibers and Computer Simulation of the Filler Dynamics in the Composite Flow
🔗 https://www.mdpi.com/2306-5354/10/4/448

📲 The publications can also be accessed via the QR codes below 👇