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Brain Sciences MDPI

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Brain Sciences (IF 2.8, CiteScore 5.6, ISSN 2076-3425; indexed in PubMed, Scopus, PMC) is an international, peer-reviewed, open access journal on neuroscience, published monthly online by MDPI.

05/06/2026

🧠 See What Your Peers Are Reading!

"Schizophrenic Consciousness in the Light of the Phenomenological Epoché: A Foundational Map for Psychiatry"

🔬 By Giovanni Stanghellini from Università degli Studi di Firenze, and Diego Portales University, Italy

💡 Highlights
What are the main findings?
- This review illustrates that schizophrenic symptoms are not discrete, unrelated deficits, but rather an integrated whole, emerging from a fundamental reorganization of consciousness.
- It establishes a conceptual kinship between the methodological suspension of the natural attitude in philosophy and the passive, involuntary collapse of reality experienced in schizophrenia...
What are the implications of the main findings?
- Schizophrenic symptoms are reframed as an immanent possibility of the human condition rather than a mere alienation from reality, providing a shared ontological ground between patient and clinician.
- The paper advocates for a hermeneutically grounded mental state examination, transforming clinical diagnosis from objective labeling into an empathetic act of shared human understanding...

🔎 Read the full study: https://brnw.ch/21x36TT MDPI

This review explores the hypothesis that schizophrenic symptoms may be understood not as isolated deficits, but as interconnected manifestations of a structural reorganization of consciousness. The premises of this work are grounded in a comparative matrix that suggests an underlying “consanguinit...

05/06/2026

⏳ Submit your research to our Special Issue!

"Research on the Neuropsychology of Adolescents"

🧠 The aim of this Special Issue is to present recent research, whether basic, clinical or applied, in order to provide a contemporary overview of adolescent neuropsychology and its theoretical and clinical challenges. Contributions may address the following areas:
- Brain maturation and cognitive development: Evolution of executive functions, social cognition, decision-making and emotional regulation.
- Clinical neuropsychology and psychopathology: Neuropsychological profiles associated with disorders that emerge in adolescence, such as eating disorders, early psychosis, depression, addictions and risky behaviours as well as the progression and manifestation of ADHD, autism spectrum disorders (ASD) and specific learning disorders during puberty.
- Individual and environmental factors: The effects of gender, sleep, stress, screen time and social media use.
- Assessment and innovative interventions: New approaches to cognitive remediation; adaptation of neuropsychological assessment tools for adolescents and the use of digital technology (apps and virtual reality).

🔬 Edited by Prof. Dr. Agnes Lacroix from Université de Rennes, Italy
📅 Deadline: 25 March 2027
👉 Explore here: https://brnw.ch/21x36L8 MDPI

Adolescence is a period of significant neurobiological, cognitive and socio-emotional change. While these changes offer developmental opportunities, they also entail specific vulnerabilities. The aim of this Special Issue is to present recent research, whether basic, clinical or applied, in order to...

04/06/2026

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"Ginkgo Biloba for Alzheimer’s Disease: From Mixed Dementia Trials to Biomarker-Confirmed Mild Cognitive Impairment—What Have We Learned over Two Decades, and Is There Finally a Bit of Hope?"

🔬 By YoungSoon Yang and Yong Tae Kwak from Soonchunhyang University Cheonan Hospital and Hyoja Geriatric Hospital (Republic of Korea)

💡 Ginkgo biloba products have been used for decades for cognitive symptoms, yet the clinical evidence in Alzheimer’s disease (AD) remains modest and heterogeneous. This review revisits key symptomatic and prevention trials and summarizes how systematic reviews and meta-analyses have informed ongoing clinical skepticism, often citing small effect sizes, limited patient-centered meaningfulness, short follow-up, and repeated trial designs.

🔎 Read the full study: https://brnw.ch/21x353i MDPI

Ginkgo biloba products have been used for decades for cognitive symptoms, yet the clinical evidence in Alzheimer’s disease (AD) remains modest and heterogeneous. This review revisits key symptomatic and prevention trials and summarizes how systematic reviews and meta-analyses have informed ongoing...

03/06/2026

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"Surgical Versus Conservative Management for Carpal Tunnel Syndrome: An Updated Systematic Review of Randomised Trials"

🔬 By Sara Masiero et al. from 9 institutions, including Mediclinic, Fairplay-Arcuri Private Functional Hand Rehabilitation, Policlinico di Modena (Italy)

💡 Highlights
What are the main findings?
- Conservative treatments provide faster short-term symptom relief.
- Surgery yields a higher probability of long-term clinical recovery.

What are the implications of the main findings?
- Conservative care may be suitable for rapid symptom control.
- Surgery should be considered for durable functional recovery.

🔎 Read the full study: https://brnw.ch/21x331X MDPI

Background: Carpal tunnel syndrome (CTS) is one of the most common entrapment neuropathies. While surgical decompression is widely considered the definitive treatment, conservative options remain clinically relevant, particularly for symptom relief and functional recovery in the short term. Objectiv...

03/06/2026

⏳ Submit your research to our Special Issue!

"Neuromarketing, Neuroeconomics, Neurotourism and Neuro-Robotics: Neural Mechanisms of Experience, Decision-Making and Interaction"

🧠 This Special Issue aims to bring together these domains by focusing on the neural and cognitive mechanisms that underpin human behaviour in complex and technology-mediated environments. It seeks to provide a platform for theoretical, methodological and applied contributions that advance the understanding of processes such as attention, perception, memory, emotion and agency in both human and human–machine contexts.

🔬 Edited by Dr. Lucilia Cardoso from Polytechnic University of Leiria (Portugal), Prof. Dr. Luiz Moutinho from University of Suffolk (UK), Dr. Carla Fraga from UFJF - Universidade Federal de Juiz de Fora (Brazil)
📅 Deadline: 15 February 2027
👉 Explore here: https://brnw.ch/21x32VI MDPI

Recent advances in neuroscience, biometrics and artificial intelligence are transforming how experience, decision making and interaction are understood across domains such as marketing, economics, tourism and human–machine systems. While neuromarketing and neuroeconomics have become well-establish...

02/06/2026

📢 All articles in Brain Sci., Volume 16, Issue 5 (May 2026) are now freely available to access, read and download! 👉 https://brnw.ch/21x31fq

🧠 Cover Paper: Noninvasive Brain Stimulation Techniques and Their Efficacy in Treating Cognition and Memory in Mild Cognitive Impairment and Alzheimer’s Disease—A Systematic Review

📝 Cover Story: This systematic review evaluates 81 studies of noninvasive brain stimulation in mild cognitive impairment and Alzheimer’s disease. Transcranial electrical stimulation appeared least expensive, more accessible, and generally well tolerated, although its benefits were often shorter-lived without repeated dosing. Transcranial magnetic stimulation showed the strongest evidence for more durable benefits, particularly in multi-session and network-targeted protocols. Transcranial focused ultrasound remains preliminary but promising because of its focality and potential to reach deeper targets. The most reproducible signals were seen in global cognition, episodic or associative memory, and selected executive functions. Overall, the field needs earlier intervention, standardized outcome measures, longer follow-up, and stronger biomarker validation.

👉 https://brnw.ch/21x31fr MDPI

This systematic review evaluates 81 studies of noninvasive brain stimulation in mild cognitive impairment and Alzheimer’s disease. Transcranial electrical stimulation appeared least expensive, more accessible, and generally well tolerated, although its benefits were often shorter-lived without rep...

01/06/2026

📢 We’re excited to share a selection of Highly Cited Papers from 2024 in the "Neuropsychology" Section!

🧠 The “Neuropsychology” Section of Brain Sciences (ISSN: 2076-3425) aims to foster research on the relationship between the brain and human cognitive, emotional, and behavioural functions. Neuropsychological testing typically assesses individual performance in several areas, including sensorimotor functions, perception, attention, spatial construction, intelligence, executive functions, memory, language, motivation, emotion, and quality of life. We encourage articles that focus on neuropsychological functions in both healthy and disordered states across the lifespan. Topics of interest include developmental areas, such as ADHD, dyslexia, and other learning disabilities, as well as adult studies that examine the cognitive and emotional consequences of conditions like stroke, traumatic brain injury, and progressive diseases such as Alzheimer’s and Huntington’s disease. We also welcome contributions that explore the development and testing of neuropsychological interventions. We envision original empirical research based on both clinical and experimental neuropsychological paradigms, along with systematic reviews, meta-analyses, and theoretical articles. Additionally, we will consider case studies that highlight critical questions on the relationship between the brain and human behaviour.

🙌 Join us in celebrating the incredible work of our researchers and their important contributions to advancing neuroscience.

📖 Read all papers here: https://brnw.ch/21x2Zrh MDPI

The “Neuropsychology” Section of Brain Sciences (ISSN: 2076-3425) aims to foster research on the relationship between the brain and human cognitive, emotional, and behavioural functions. Neuropsychological testing typically assesses individual performance in several areas, including sensorimotor...

01/06/2026

📢 Discover the latest research in drugs and treatment targets in brain cancers!

🧠 Our Special Issue "New Advances in the Development of New Drugs and Treatment Targets for Brain Cancers (2nd Edition)" has published 6 papers!

🔬 Edited by Dr. Luis Exequiel Ibarra, Dr. Laura Natalia Milla Sanabria from National Council for Scientific and Technical Research (CONICET) and National University of Río Cuarto (UNRC), Argentina, Dr. Nuria Arias-Ramos from Instituto de Investigaciones Biomedicas Alberto Sols (IIBM), Spain

👉 Read the collection and explore new insights shaping the future of brain research at https://brnw.ch/21x2Zkm MDPI

Brain malignancies pose a substantial obstacle for the field of oncology and the advancement of pharmaceuticals. Historically, the treatment of brain tumors has been challenging due to their physical and molecular characteristics. The tumor's exposure to systemic therapy may be diminished by the blo...

29/05/2026

📢 See What Your Peers Are Reading!

🧠 Regenerative Medicine Strategies for Spinal Cord Injury: Advances in Stem Cell Therapy

🔬 By Ahmed I. Anwar, Alaa Abd-Elsayed and Alan D. Kaye from Louisiana State University Health Sciences Center at Shreveport, University of Wisconsin-Madison (USA)

💡 Highlights
What are the main findings?
- Stem cell therapies have demonstrated regenerative potential in preclinical models of spinal cord injury
- Clinical studies have reported variable improvements in motor, sensory, and autonomic outcomes

What are the implications of the main findings?
- Stem cell therapies may offer therapeutic benefit, but clinical efficacy remains uncertain due to heterogenous outcomes
- Further standardized clinical studies are needed to determine the safety and effectiveness of stem cell therapies for spinal cord injury

🔎 Read the full study: https://brnw.ch/21x2VtN MDPI

Spinal cord injuries disrupt the motor, sensory, and autonomic functions routinely carried out by the spinal cord, with injury progressing from primary mechanical damage from the initial trauma to a secondary phase driven by inflammation and cellular cascades. This disruption significantly impacts t...

29/05/2026

⏳ Submit your research to our Special Issue!

"Modern Aspects of Neurorehabilitation"

🧠 Neurology has made groundbreaking advances in recent decades, including, for example, gene therapy approaches for neuromuscular disorders and improvements in immunomodulatory therapies for multiple sclerosis. As a result, an increasing number of patients are being successfully treated. As neurology advances, so too does the importance of neurorehabilitation, which has evolved into a thriving clinical discipline and field of science...

🔬 Edited by Dr. Hans-Jürgen Gdynia from m&i-Fachklinik Enzensberg, Germany
📅 Deadline: 31 March 2027
👉 Explore here: https://brnw.ch/21x2Vlv MDPI

Neurology has made groundbreaking advances in recent decades, including, for example, gene therapy approaches for neuromuscular disorders and improvements in immunomodulatory therapies for multiple sclerosis. As a result, an increasing number of patients are being successfully treated. As neurology ...

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