Journal of Personalized Medicine MDPI

12/12/2025

🚺🚹 Why S*x Matters in Heart Failure Care

🚀 This review delves into the critical s*x-based differences in heart failure—from remodeling patterns to treatment gaps and clinical outcomes.

🔐 Key insights include:

• more often present with concentric remodeling & diastolic dysfunction
• Men more often present with eccentric remodeling & systolic dysfunction
• Supra-normal LVEF may carry unique risks, especially in women
• Persistent disparities exist in guideline-directed medical therapy

Understanding these phenotypes is essential for personalized, effective care.

"S*x Differences in Cardiac and Clinical and Their Relation to Outcomes in Patients with Heart Failure"

🔗 https://brnw.ch/21wYi04

Biological s*x is one of the major factors characterizing the heart failure (HF) patient phenotype.

12/12/2025

🏃‍♂️💎 How Reshapes the ’s Response to ***ne

🐁 Exciting new research explores whether physical activity can alter the brain’s reaction to chronic co***ne use—in male rats.

Title: Exercise Influences the Brain’s Metabolic Response to Chronic Co***ne Exposure in Male Rats

Authors: Aidan Powell et al. | State University of New York at Buffalo
🔗 Full article here: https://brnw.ch/21wYhZm

***ne 🧠🏃💡

Co***ne use is associated with negative health outcomes: co***ne use disorders, speedballing, and overdose deaths. Currently, treatments for co***ne use disorders and overdose are non-existent when compared to opioid use disorders, and current standard co***ne use disorder treatments have high dropo...

11/12/2025

🫁 Integrating Mental Health into Care: New Insights

Title: "Diagnosis of Anxiety in COPD Patients: Usefulness of the HADS Test in Primary Care and Pulmonology Services"

Managing COPD goes beyond the . This study investigates the prevalence of in patients moving from primary to specialist care and identifies predictive factors.

💡 The findings strongly support the routine use of simple diagnostic tools like the Hospital Anxiety and Depression Scale ( ). This facilitates early identification and referral, underscoring the need for holistic patient management.

📄 Explore the research that advocates for systematic psychological evaluation in COPD protocols: https://brnw.ch/21wYfV8

Anxiety disorders, characterized by excessive fear and anxiety, are increasingly recognized as significant comorbidities in chronic diseases such as chronic obstructive pulmonary disease (COPD).

11/12/2025

🧪 We're Headed to Osaka! 🗾

We are thrilled to announce that JPM will be exhibiting at The 146th Annual Meeting of the Society of Japan! 🤝

📍 Where: Osaka, Japan
🗓️ When: 26–29 March 2026

👉 Find our booth to:
• Discuss your latest research ideas 💡
• Explore publishing opportunities with us 📖
• Network with peers driving innovation 🌐

More info: https://brnw.ch/21wYfUh

Let's collaborate to advance science beyond boundaries! We can't wait to connect. See you in Osaka! ✨

Journal of Personalized Medicine, an international, peer-reviewed Open Access journal.

10/12/2025

🎗️ Study Spotlight: Understanding Progressive Lung Disease in Sjogren Syndrome

📚 Article: "Prevalence of Progressive Fibrosing Interstitial Disease in Patients with Primary Syndrome"

👩‍🎓 Authored by Andreina Manfredi et al., Azienda Ospedaliera Policlinico di Modena

🔍 This research highlights the significant risk of progressive fibrosing in patients with Primary Sjogren Syndrome. Notably, both UIP and NSIP patterns showed similar progression—with NSIP evolving more frequently than in other diseases. Early recognition is critical for timely intervention and careful long-term management.

📄 Read the full study here: https://brnw.ch/21wYdMw

Background: Interstitial lung disease (ILD) represents a frequent cause of morbidity and mortality in primary Sjogren syndrome (pSS).

10/12/2025

🎉 Exciting News for Personalized Medicine in Brazil! 🎉

We are thrilled to announce that the Brazilian Society of Personalized Medicine ( ) 🇧🇷 is now an Affiliated Society Member of the 𝓙𝓸𝓾𝓻𝓷𝓪𝓵 𝓸𝓯 𝓟𝓮𝓻𝓼𝓸𝓷𝓪𝓵𝓲𝔃𝓮𝓭 𝓜𝓮𝓭𝓲𝓬𝓲𝓷𝓮 (JPM)!

📅 As of November 2025, this partnership opens new doors for collaboration and knowledge sharing in the field of individualized healthcare.

🤝 This collaboration aligns perfectly with JPM’s mission to advance tailored healthcare solutions worldwide. Together, we look forward to showcasing groundbreaking research from Brazil’s brilliant scientific community!

📢 Spread the word! If you’re an SBMP member, now is the perfect time to submit your work!

🧬📚🌍

09/12/2025

📚 Enjoy Reading! “Enhancing Management: Personalized Medicine Insights from Rural🏞️ and Urban🏙️ General Practitioner Practices”

🥼 by Marta Duda-Sikuła & Donata Kurpas (Wroclaw Medical University)

🔗 Dive into the full article here: https://brnw.ch/21wYc8J

Health policies worldwide emphasize managing chronic conditions like diabetes and hypertension through medication and lifestyle modifications. However, translating guidelines into practical application remains challenging, leading to suboptimal care and poor health outcomes, particularly in low-reso...

08/12/2025

🎁 Editor's Choice Paper

"The Safety and Efficacy of Sodium-Glucose Cotransporter-2 Inhibitors for Patients with or : Double Edged Sword?"

🧑‍🎓 Ayami Naito et al., (National Defense Medical College) summarize the of frailty assessment and discuss the efficacy and safety of -2i for patients with sarcopenia or frailty.

▶️ Read the full paper: https://brnw.ch/21wYa2O

Sodium-glucose cotransporter-2 inhibitors (SGLT-2is) show cardiovascular protective effects, regardless of the patient’s history of diabetes mellitus (DM). SGLT2is suppressed cardiovascular adverse events in patients with type 2 DM, and furthermore, SGLT-2is reduced the risk of worsening heart fai...

05/12/2025

🤰 Call-for-Reading "Management of “De Novo” Carpal Tunnel Syndrome in : A Narrative Review"

⚠️Carpal tunnel syndrome ( ) is common during pregnancy but often missed—symptoms are mistaken for typical pregnancy changes. Undiagnosed, it can cause permanent nerve damage, impacting a mother's quality of life.

🤝Treatment is tricky: options are limited during pregnancy, yet symptoms may resolve postpartum. That's why early & a , multidisciplinary team approach is essential for prevention and care.

🦋 This paper assesses the current measures for pregnancy-related carpal tunnel syndrome ( ).

🎁 Enjoy reading: https://brnw.ch/21wY64p

Carpal tunnel syndrome is a common entrapment neuropathy that can occur in the upper limbs during pregnancy.

05/12/2025

🏆 Editor's Choice

"Evolving Management of Cancer in the Era of and Precision Medicine"

✍️ Authors: Muhammad Zubair Afzal & Linda T. Vahdat (Dartmouth Cancer Center)
👁️ 5,368 views | 8 citations
📄 Full paper: https://brnw.ch/21wY64c

Breast cancer is the most common cancer among women in the world as well as in the United States.

04/12/2025

🚀 𝗧𝗵𝗲 𝗔𝗜 𝗥𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗙𝗿𝗼𝗻𝘁𝗶𝗲𝗿: 𝗛𝗶𝗴𝗵𝗹𝘆 𝗖𝗶𝘁𝗲𝗱 𝗣𝗮𝗽𝗲𝗿𝘀 & 𝗖𝗮𝗹𝗹 𝗳𝗼𝗿 𝗣𝗮𝗽𝗲𝗿𝘀🧠

The field of Artificial Intelligence is advancing at a phenomenal pace, and its application in precision medicine is transforming patient care. At the 𝓙𝓸𝓾𝓻𝓷𝓪𝓵 𝓸𝓯 𝓟𝓮𝓻𝓼𝓸𝓷𝓪𝓵𝓲𝔃𝓮𝓭 𝓜𝓮𝓭𝓲𝓬𝓲𝓷𝓮, we are proud to contribute at this critical intersection. We are excited to share a key resource showcasing the high-impact research that is defining the future of medicine.

📊 𝗛𝗶𝗴𝗵𝗹𝘆 𝗖𝗶𝘁𝗲𝗱 & 𝗧𝗿𝗲𝗻𝗱𝗶𝗻𝗴 𝗥𝗲𝘀𝗲𝗮𝗿𝗰𝗵:
🔸 Applications of AI in
🔹 Digital Twins
🔸 AI for Care
🔹 Leveraging for Wearable Devices
🔸 AI for Assessment and Early Detection

👉 Dive into the full list of highly cited papers and discover the Special Issue that matches your research here: https://brnw.ch/21wY3VV

Let's discuss the future of medicine in the comments! 💬

We are delighted to share some of the highly cited papers on artificial intelligence that were published in the Journal...

03/12/2025

📢 𝗦𝗵𝗮𝗿𝗶𝗻𝗴 𝘁𝗵𝗲 𝗜𝗺𝗽𝗮𝗰𝘁: 𝗢𝘂𝗿 𝗧𝗼𝗽 𝗥𝗵𝗲𝘂𝗺𝗮𝘁𝗼𝗹𝗼𝗴𝘆 𝗣𝗮𝗽𝗲𝗿𝘀! 📢

We're proud to highlight a curated collection of Highly Cited Papers from the 𝓙𝓸𝓾𝓻𝓷𝓪𝓵 𝓸𝓯 𝓟𝓮𝓻𝓼𝓸𝓷𝓪𝓵𝓲𝔃𝓮𝓭 𝓜𝓮𝓭𝓲𝓬𝓲𝓷𝓮 that are advancing research. These influential studies showcase the best in precision medicine for conditions like:

🔸 Psoriatic
🔹 Arthritis
🔸 Systemic Lupus Erythematosus
🔹

This body of work is shaping clinical understanding and inspiring the next generation of research. We invite the community to read, share, and discuss this impactful science.

👉 Explore the Highly Cited Papers here: https://brnw.ch/21wY1LZ

𝙋.𝙎. 𝙄𝙣𝙨𝙥𝙞𝙧𝙚𝙙 𝙩𝙤 𝙘𝙤𝙣𝙩𝙧𝙞𝙗𝙪𝙩𝙚? We have several Hot Topic Special Issues open for your groundbreaking submissions.

We are delighted to share some of the highly cited papers on rheumatology that were published in Journal of Personalized...