GigaScience

21/01/2026

Making machine learning research more transparent and reproducible: GigaScience Press integrates DOME standards into peer review and publishing workflows.

Check out how structured annotations and a public registry are enhancing trust and reuse in ML-based science. https://doi.org/10.5334/dsj-2026-001

04/01/2026

A major genomic leap for cold-adapted insects! We present four chromosome-level genomes for Diamesa midges, revealing how gene family changes—like expansions in cryoprotectant genes—underpin their survival in glacial ecosystems. https://doi.org/10.1093/gigascience/giaf160

04/01/2026

Unlocking the “dark matter” of the genome: Harvard study reveals over half of structural variants are hidden in low-complexity regions, where error rates soar. https://doi.org/10.1093/gigascience/giaf154

05/12/2025

How robust is your analysis? Our new study shows bioinformatics reprocessing choices matter less than you think.
The effects of bioinformatics preprocessing on cell-free DNA fragment analysis:

AbstractBackground. While cell-free DNA (cfDNA) is a promising biomarker for cancer diagnosis and monitoring, there is limited agreement on optimal cfDNA c

02/12/2025

The complete genome of a tiny liverwort unlocks secrets of genome evolution in early land plants.

Giant chromosomes of a tiny plant - the complete telomere-to-telomere genome assembly of the simple thalloid liverwort Apopellia endiviifolia (Jungermanniopsida, Marchantiophyta): https://doi.org/10.1093/gigascience/giaf145