The Lancet

The Lancet The Lancet Group is a collection of 24 medical & health journals united by a shared vision – publishing the best science for better lives,

The Lancet began as an independent, weekly general medical journal founded in 1823 by Thomas Wakley. Since its first issue, the journal has addressed urgent medical and health-related topics, initiated debate, and influenced decision-makers around the world. In 2023, we celebrated The Lancet’s 200th year and its evolution into a Group of 24 journals spanning a wide range of fields and world region

s. After two centuries, The Lancet Group retains, at its core, the belief that medicine must serve society, that knowledge must transform society, and that the best science must lead to better lives. To find out more about, visit www.thelancet.com. The Lancet is a trade mark of RELX Intellectual Properties SA, used under license.

On this week’s cover of The Lancet, a World Report discusses the neglect of meliodosis, a fatal but preventable infectio...
11/10/2025

On this week’s cover of The Lancet, a World Report discusses the neglect of meliodosis, a fatal but preventable infection.

Over 165,000 cases of melioidosis are estimated to occur every year, although experts say the true burden is unknown.

Read this & more in the latest issue ▶️ https://hubs.li/Q03N4RYB0

Decompensated cirrhosis is an advanced stage of liver disease which often requires a liver transplant.A new Review looks...
10/10/2025

Decompensated cirrhosis is an advanced stage of liver disease which often requires a liver transplant.

A new Review looks at how treating the causes of cirrhosis can help reverse liver scarring and improve liver function, and avoid the need for transplantation. Find out more via the link below ⤵️

📊 Figure: Transition from decompensated cirrhosis to recompensated cirrhosis following cure or control of the causative factor for chronic liver disease.

10/10/2025

🎤 More global leaders speaking at

The World Health Summit 2025 is just around the corner. On stage, these global leaders will come together in collaboration and dialogue to shape the future of :

-> Helen Clark, Chair of the Board, Alliance for Health Policy and Systems Research, New Zealand

-> Richard Horton, Editor-in-Chief, The Lancet, United Kingdom

-> Mohamed Janabi, Regional Director for Africa, World Health Organization (WHO)

-> Jane Halton, Chair, Coalition for Epidemic Preparedness Innovations (CEPI), Norway

-> Diene Keita, Executive Director, United Nations Population Fund (UNFPA)

-> Hans Kluge, Regional Director for Europe, World Health Organization (WHO)

-> Precious Matsoso, Intergovernmental Negotiating Body Co-Chair, World Health Organization (WHO)

-> Saia Ma'u Piukala, Regional Director for the Western Pacific, World Health Organization (WHO)

-> Hanan Balkhy, Regional Director for the Eastern Mediterranean, World Health Organization (WHO)

-> Olivér Várhelyi, European Commissioner for Health and Animal Welfare, European Commission

-> John-Arne Røttingen, CEO, Wellcome Trust, United Kingdom

-> Jayasree Iyer, CEO, Access to Medicine Foundation, The Netherlands

Explore the full lineup of speakers and register today: https://f.mtr.cool/ksxvuihsvn

📍 Berlin & Online 📅 October 12–14, 2025

📢 Join us for our Lancet Webinar on reporting race and ethnicity data in Lancet journals.📆 Thursday, October 23 at 11am ...
10/10/2025

📢 Join us for our Lancet Webinar on reporting race and ethnicity data in Lancet journals.

📆 Thursday, October 23 at 11am BST

Our editors will guide you through The Lancet Group's guidance on reporting race and ethnicity in your research, discuss how disaggregating race and ethnicity data can reveal and help tackle health inequities, and provide practical tips for all article types.

👤 Featuring expert editors from across The Lancet Group, including:
Mabel Chew (Senior Editor, The Lancet)
Zoë Mullan (Editor-in-Chief, The Lancet Global Health)
Pooja Jha (Editor-in-Chief, The Lancet Regional Health—Europe)

👉 Register now to secure your place: https://hubs.ly/Q03LGnHq0

Oncolytic viruses have the unique ability to selectively replicate within (and to destroy) cancer cells, offering a prom...
08/10/2025

Oncolytic viruses have the unique ability to selectively replicate within (and to destroy) cancer cells, offering a promising approach in cancer treatment.

A new Review summarises clinical progress, remaining challenges, & future research directions. Find out more via the link in comments ⤵️

📊 Figure: Oncolytic viruses—increasing the heat of the tumour microenvironment.

Psoriatic arthritis is a common form of inflammatory arthritis, characterised by synovial inflammation.A new Review disc...
06/10/2025

Psoriatic arthritis is a common form of inflammatory arthritis, characterised by synovial inflammation.

A new Review discusses improved understanding of psoriatic arthritis, including potential biomarkers and new treatment targets, and future directions for synovial studies.

Find out more via the link in comments ⤵️

Figure: Previously identified cell types and cytokines implicated in psoriatic arthritis pathogenesis in the synovial fluid and synovial tissue.

❓Do you have questions about s*x and gender reporting in your research? Now is your chance to ask our editors!Join our u...
06/10/2025

❓Do you have questions about s*x and gender reporting in your research? Now is your chance to ask our editors!

Join our upcoming webinar, where we are bringing together an expert panel to discuss the importance of s*x- and gender-based analyses in medical research, and explore the requirements of the SAGER guidelines.

Bring your questions for the live Q&A session and get some practical tips for responding to the guidelines.

👉 Register today to secure your place: https://hubs.ly/Q03FRMnX0

The treatment of type 1 diabetes is entering a transformative era.A recent Review explores three paradigm-shifting devel...
05/10/2025

The treatment of type 1 diabetes is entering a transformative era.

A recent Review explores three paradigm-shifting developments poised to transform type 1 diabetes treatment. Find out more via the link in comments ⤵️

📊 Figure: Production and transplantation of β cells derived from embryonic or induced pluripotent stem cells.

On this week’s cover of The Lancet, a new letter: “Gaza’s healthocide: medical societies must not stay silent”. Read the...
04/10/2025

On this week’s cover of The Lancet, a new letter: “Gaza’s healthocide: medical societies must not stay silent”.

Read the letter and more in our latest issue: https://hubs.li/Q03M2Sqj0

🌍 Despite enough food being produced globally, billions lack access to healthy, sustainable diets.⁠⁠The new EAT Foundati...
03/10/2025

🌍 Despite enough food being produced globally, billions lack access to healthy, sustainable diets.⁠
⁠
The new EAT Foundation–Lancet report presents a science-based approach to improve health, safeguard our environment, and provide for a projected 9.6 billion people by 2050. ⁠
⁠
It highlights that a flexible, plant-rich “Planetary Health Diet”— emphasising minimally processed, plant-rich foods with moderate animal products—can reduce risks of certain chronic diseases and support planetary health. ⁠
⁠
As Commission co-chair Walter C. Willett explains, “The Planetary Health Diet is not a one-size-fits-all approach”; it accounts for cultural diversity and individual preferences within scientifically informed guidelines to support health and sustainability worldwide. ⁠
⁠
🔗 Find out more via the link in the comments.
⁠
Alt: Cover of the 2025 EAT–Lancet report, featuring an image of a person scooping up green vegetables in their hands from a large plate. The report quote: “The targets of the EAT–Lancet Commission for healthy people on a healthy planet with just food systems can only be met through concerted global action and unprecedented levels of transformative change.”

❓How can we ensure that research publishing actively contributes to better and more equitable health outcomes for everyo...
03/10/2025

❓How can we ensure that research publishing actively contributes to better and more equitable health outcomes for everyone?

Join us for a Lancet Webinar on "Reporting race and ethnicity data in Lancet journals: a pathway to improving health outcomes and equity in research and clinical practice."

Together, we will explore The Lancet Group's guidance on reporting race and ethnicity. Our guidance aims to increase transparency and clinical relevance, and reduce bias in publishing for better health outcomes.

In this interactive discussion, Editors from across The Lancet Group will:
🔹Explore how disaggregating race and ethnicity data can reveal and help tackle health inequities.
🔹Discuss how this guidance encourages authorship diversity and inclusive research practices.
🔹Provide practical tips for authors and answer questions from attendees.

Register now to secure your place: https://hubs.li/Q03KNctk0

Shigellosis is the most common cause of invasive bloody diarrhoea in children younger than 5 years.The prevention of inf...
02/10/2025

Shigellosis is the most common cause of invasive bloody diarrhoea in children younger than 5 years.

The prevention of infection with vaccination & sanitation strategies remains a crucial step in reducing worldwide morbidity & mortality.

Find out more via the link in comments ⤵️

📊 Figure: The immunopathogenesis of Shigella infection in the colon.

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