The Lancet

The Lancet The Lancet Group is a collection of 24 medical & health journals united by a shared vision – publishing the best science for better lives,

The Lancet began as an independent, weekly general medical journal founded in 1823 by Thomas Wakley. Since its first issue, the journal has addressed urgent medical and health-related topics, initiated debate, and influenced decision-makers around the world. In 2023, we celebrated The Lancet’s 200th year and its evolution into a Group of 24 journals spanning a wide range of fields and world region

s. After two centuries, The Lancet Group retains, at its core, the belief that medicine must serve society, that knowledge must transform society, and that the best science must lead to better lives. To find out more about, visit www.thelancet.com. The Lancet is a trade mark of RELX Intellectual Properties SA, used under license.

Small, preclinical studies on breast tissue suggest mifepristone shows promise for reducing the risk of breast cancer.Ho...
16/08/2025

Small, preclinical studies on breast tissue suggest mifepristone shows promise for reducing the risk of breast cancer.

However the use of mifepristone for medical abortion has created barriers for developing it for other purposes, highlights a new Viewpoint.

Find out more via the link in comments 👇

Image copyright: Wladimir Bulgar/Science Photo Library

The global burden of liver cancer is increasing, with new cases set to double by 2050.On the cover, the latest Commissio...
15/08/2025

The global burden of liver cancer is increasing, with new cases set to double by 2050.

On the cover, the latest Commission report on addressing the global hepatocellular carcinoma burden.

This and more in our latest issue 👉 https://hubs.li/Q03CWwpD0

Epilepsy is the most common chronic neurological disease in children. Explore ways of optimising outcomes in this new Se...
14/08/2025

Epilepsy is the most common chronic neurological disease in children.

Explore ways of optimising outcomes in this new Seminar, link below ⤵️

📊 Figure: A list of age-specific epilepsy syndromes from 0 to 10 years.

Routine AI assistance may lead to loss of skills in health professionals who perform colonoscopies, study suggests.The a...
13/08/2025

Routine AI assistance may lead to loss of skills in health professionals who perform colonoscopies, study suggests.

The average rate of adenoma detection at non-AI assisted colonoscopies significantly decreased from 28.4% before AI exposure to 22.4% after AI exposure.

Find out more via the link below 👇

154 million lives saved 💉In 1974, the Expanded Programme on Immunization (EPI) was launched by the World Health Organiza...
12/08/2025

154 million lives saved 💉

In 1974, the Expanded Programme on Immunization (EPI) was launched by the World Health Organization to tackle high rates of vaccine-preventable disease.

50 years on, at least 154 million lives have been saved.

Learn more about this public health success in The Lancet ➡️ https://hubs.li/Q03CjFQr0

🗨️ “Stakeholders need to protect the gains of EPI, sustain coverage, target remaining gaps, and think of immunisation programmes as the foundation...of strong and resilient health systems”, say authors.

Figure below: Deaths averted, years of life saved, and years of full health gained due to vaccination

Advancements over the past decade in understanding vesicular monoamine transporter 2 (VMAT2) inhibitors highlight their ...
11/08/2025

Advancements over the past decade in understanding vesicular monoamine transporter 2 (VMAT2) inhibitors highlight their key role in the treatment of movement and neuropsychiatric disorders.

A new Review explores its current uses and future directions. Find out more via the link in the comments below 👇

📊 Figure: VMATs

Low back pain is a long-term health condition for many people marked by unpredictable recurrences or pain flare ups.A ne...
10/08/2025

Low back pain is a long-term health condition for many people marked by unpredictable recurrences or pain flare ups.

A new trial on cognitive functional therapy, the first psychotherapy treatment for chronic disabling low back pain, presents strong evidence that it can effectively reduce disability due to the pain for more than a year.

Find out more via the link in comments below. 👇

The oncogenic KRAS mutation has been the subject of intense investigation. In The Lancet, a new phase 3 trial reports on...
09/08/2025

The oncogenic KRAS mutation has been the subject of intense investigation.

In The Lancet, a new phase 3 trial reports on adagrasib versus docetaxel in KRASG12C-mutated non-small-cell lung cancer.

This and more in our latest issue 👉 https://hubs.li/Q03BWnwm0

💊 Penicillin is often used to treat bacterial infections, except for the 5-8% of adults and children have a penicillin a...
08/08/2025

💊 Penicillin is often used to treat bacterial infections, except for the 5-8% of adults and children have a penicillin allergy label in their medical records.

However less than 10% of patients with penicillin allergy labels are truly allergic when formally assessed. A new trial explores how checking for penicillin allergies can help doctors prescribe more targeted penicillin antibiotics safely.

Read the report of the ALABAMA trial, link below 👇

The importance and impact of the menstrual cycle on health across the lifespan have long been underappreciated.Documenti...
07/08/2025

The importance and impact of the menstrual cycle on health across the lifespan have long been underappreciated.

Documenting the menstrual cycle as a vital sign, in both clinical and research contexts, has the potential to significantly improve patient wellbeing, care, and public health.

Find out more from our latest Viewpoint, link below 👇

Stay ahead in your field! 📣Connect directly to late-breaking content published by The Lancet Group presented at global c...
07/08/2025

Stay ahead in your field! 📣

Connect directly to late-breaking content published by The Lancet Group presented at global conferences and related events in your field, right from your inbox. Find out more & register via the link in the comments 👇

🆕 Clinical Picture: Epithelioid sarcoma presenting as a progressively enlarging woundA healthy 57-year-old female patien...
06/08/2025

🆕 Clinical Picture: Epithelioid sarcoma presenting as a progressively enlarging wound

A healthy 57-year-old female patient presented at hospital with a 6-month history of a progressively enlarging wound on her left forearm. She reported no systemic symptoms or prior trauma.

Find out more on this case via the link in comments 👇

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