The Lancet

The Lancet The Lancet Group is a collection of 29 medical & health journals united by a shared vision – publishing the best science for better lives,

The Lancet began as an independent, weekly general medical journal founded in 1823 by Thomas Wakley. Since its first issue, the journal has addressed urgent medical and health-related topics, initiated debate, and influenced decision-makers around the world. In 2023, we celebrated The Lancet’s 200th year and its evolution into a Group of 24 journals spanning a wide range of fields and world region

s. After two centuries, The Lancet Group retains, at its core, the belief that medicine must serve society, that knowledge must transform society, and that the best science must lead to better lives. To find out more about, visit www.thelancet.com. The Lancet is a trade mark of RELX Intellectual Properties SA, used under license.

The shortage of human kidneys is a critical problem in transplantation. Many candidates die or are removed from the wait...
10/09/2026

The shortage of human kidneys is a critical problem in transplantation. Many candidates die or are removed from the waiting list before an organ becomes available.

Transplanting genetically engineered pig organs has been proposed as a solution to the organ shortage.

According to a world-first report published in The Lancet, a genetically modified pig kidney kept a man off dialysis for nine months before a successful human kidney transplant.

The authors of the report say the findings support pig kidney transplantation as a potential bridge for people facing long waits for a human kidney, while highlighting the need for further research.

Read the full report: http://spkl.io/61827ReJ6

Retroperitoneal fibrosis is a rare immune-mediated disease which can be classified as idiopathic or secondary.A Seminar ...
09/09/2026

Retroperitoneal fibrosis is a rare immune-mediated disease which can be classified as idiopathic or secondary.

A Seminar provides an overview of retroperitoneal fibrosis focusing on pathophysiology, differential diagnosis, and management: http://spkl.io/618673req

👇 Figure: [18F]-fluorodeoxyglucose-PET scans in a patient with idiopathic retroperitoneal fibrosis showing a hypermetabolic tissue surrounding the lower abdominal aorta.

Chronic hypoparathyroidism is a rare endocrine disorder characterised by hypocalcaemia & hyperphosphataemia due to the a...
08/09/2026

Chronic hypoparathyroidism is a rare endocrine disorder characterised by hypocalcaemia & hyperphosphataemia due to the absence or severe deficiency of parathyroid hormone (PTH).

A new Review, summarises the scientific and medical findings presented at the Hypoparathyroidism 2025 Summit, which includes potential advanced therapies & recent progress in parathyroid transplant and cell therapy: http://spkl.io/61867RMG0

👇 Figure: CaSR structure and cell-specific signalling by multiple G-proteins pathway.

A genetically modified pig kidney kept a 66-year-old man with kidney failure free of dialysis for a record nine months, ...
07/09/2026

A genetically modified pig kidney kept a 66-year-old man with kidney failure free of dialysis for a record nine months, according to the first report of its kind published in The Lancet.

This is also the first time a pig kidney has been used as a temporary “bridge” to a human transplant.

Authors say the findings support pig kidney transplantation as a potential bridge for people facing long waits for a human kidney, while highlighting the need for further research. Find out more ▶️ http://spkl.io/61857RElV

👇 Figure: Clinical course.

🫁 Lung cancer treatment is changing—and so is our understanding of how best to treat different forms of the disease.A ne...
07/09/2026

🫁 Lung cancer treatment is changing—and so is our understanding of how best to treat different forms of the disease.

A new The Lancet–The Lancet Respiratory Medicine Series, presented at the , explores the evolving therapeutic landscape across:

👉 Early-stage non-small-cell lung cancer (NSCLC)
👉 Advanced NSCLC
👉 Small-cell lung cancer

From immunotherapy and targeted treatments to comprehensive molecular profiling and other emerging approaches, the Series examines both progress and the questions still to be answered.

The shared challenge: turning increasingly complex science into evidence-based, individualised—and equitable—care.

Find out more: http://spkl.io/61827uqk6

Cardiovascular disease is one of the leading causes of maternal mortality & a major driver of morbidity.In our latest is...
05/09/2026

Cardiovascular disease is one of the leading causes of maternal mortality & a major driver of morbidity.

In our latest issue, a new Lancet Series examines the continuum of cardiovascular risk surrounding pregnancy.

Read this & more: http://spkl.io/61817uWWh

A new Clinical Rounds article emphasizes the importance of resisting cognitive bias in cancer patients through reflectiv...
04/09/2026

A new Clinical Rounds article emphasizes the importance of resisting cognitive bias in cancer patients through reflective reassessment and biopsy confirmation.

Read now ▶️ http://spkl.io/61877uWU3

👇 Figure: (A) Dense dermal infiltrate composed of large cells with pale cytoplasm and vesicular nuclei (haematoxylin and eosin; ×400 magnification). (B) Immunohistochemical staining showing strong CD68 expression in lesional cells (×400 magnification).

Painful periods during adolescence linked to symptoms that began years earlier, with Black and Hispanic girls more likel...
03/09/2026

Painful periods during adolescence linked to symptoms that began years earlier, with Black and Hispanic girls more likely to be affected, study suggests.

Find out more ▶️ http://spkl.io/61837uggN

Figure: Research in context panel.

Psoriasis is a common, chronic, immune-mediated skin disease affecting more than 40 million people worldwide. Key psoria...
02/09/2026

Psoriasis is a common, chronic, immune-mediated skin disease affecting more than 40 million people worldwide.

Key psoriasis risk factors include genetic polymorphisms (most notably HLA-C*06:02), obesity, and environmental factors such as trauma, infections, and specific medications.

In The Lancet, a new Seminar provides an updated survey of our knowledge on psoriasis, its clinical management, and future challenges. Read: http://spkl.io/61857un1h

Alt: Pathophysiological features of psoriasis. (A) Characteristic histopathological features of plaque psoriasis. (B) Key immunopathological cells and mediators of plaque psoriasis.

Read the latest research, reviews, and commentaries published across The Lancet Group, free to access.Visit the Lancet...
01/09/2026

Read the latest research, reviews, and commentaries published across The Lancet Group, free to access.

Visit the Lancet Ebola Collection: http://spkl.io/618978Vvb

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