The Lancet

The Lancet Group is a collection of 24 medical & health journals united by a shared vision – publishing the best science for better lives,

The Lancet began as an independent, weekly general medical journal founded in 1823 by Thomas Wakley. Since its first issue, the journal has addressed urgent medical and health-related topics, initiated debate, and influenced decision-makers around the world. In 2023, we celebrated The Lancet’s 200th year and its evolution into a Group of 24 journals spanning a wide range of fields and world region

s. After two centuries, The Lancet Group retains, at its core, the belief that medicine must serve society, that knowledge must transform society, and that the best science must lead to better lives. To find out more about, visit www.thelancet.com. The Lancet is a trade mark of RELX Intellectual Properties SA, used under license.

24/07/2025

Primary biliary cholangitis is a chronic autoimmune liver disease, which can result in cholestasis & secondary biliary cirrhosis, especially when left untreated.

A recent Review looks at how new treatments and advances can improve personalised care to control liver damage, relieve symptoms & prevent severe liver disease.

Discover more via the link in comments below. 👇

Figure: Treat-to-target approach in primary biliary cholangitis.

23/07/2025

2025 marks 6 years since the first South Asian Heritage Month was launched in the UK. On August 7, join us for a webinar event exploring this year’s theme, ‘Roots to Routes’.

Panelists:
🔹 Subhadra Das: Writer, historian, curator, and comedian
🔹 Rohini Mathur: Academic, data Scientist, and epidemiologist
🔹 Zeshan Qureshi: Paediatrician, academic, and writer

Register today ⤵️
https://hubs.li/Q03xRslD0

22/07/2025

Alzheimer’s disease is the main cause of dementia. It is quickly becoming one of the most expensive, lethal, and burdening diseases of this century.

In general, neurological disorders are the leading cause of disease burden, affecting more than 3 billion people worldwide.

To advance our mission of the best science for better lives, The Lancet has issued a call for papers for a dedicated issue on neurology. Learn more about the research we are looking for, link in comments below. ⤵️

💬 The figure is from a recent Review: Differences between individuals susceptible or resilient to Alzheimer's disease.

21/07/2025

💻 AI tool can estimate biological age and improve predictions of survival outcomes for patients with cancer, suggests study.

The FaceAge artificial intelligence system was trained on over 50,000 photos of presumed healthy individuals from public datasets.

Find out more via the link below. 👇

Figure: Overview of FaceAge algorithm using a single photograph of the face as input. (B) Overview of the datasets used in this study. (C) Overview of the clinical experiments performed in this study to assess the clinical utility of FaceAge.

19/07/2025

📢 We're now inviting submissions for our annual essay competition, the .

Put pen to paper and share your thought provoking and original ideas about centring care in medicine.

Find out more about this year’s theme and enter today: https://hubs.li/Q03xRmRL0

18/07/2025

Chronic respiratory diseases constitute one of the most pressing, yet underappreciated, global health burdens.

A new Lancet Respiratory Medicine Series explores the epidemiology of asthma, COPD, & ILD & discusses policy solutions to improve diagnosis & access to care.

Find out more via the link in comments 👇

17/07/2025

The Lancet Commission on One Health is live ⚡

Over the past few years, One Health—highlighting the fundamental links between human, animal, and environmental health—has grown in visibility and importance.

Now, there is a landmark Pandemic Agreement embracing a One Health approach.

But what does One Health mean for antimicrobial resistance, non-communicable diseases, food systems, and our most pressing health and sustainability challenges?

And what needs to happen to ensure a One Health approach fit for the future?

🗨️ “The Lancet One Health Commission provides a cutting-edge appraisal of where One Health has come from, where it is now, and what a viable future should be”, say authors of the new report.

Discover their 10 expert recommendations in the comments section ⤵️

Figure: A map of the socioecological system

16/07/2025

💊 Penicillin is often used to treat bacterial infections, except for the 5-8% of adults and children have a penicillin allergy label in their medical records.

However less than 10% of patients with penicillin allergy labels are truly allergic when formally assessed. A new trial explores how checking for penicillin allergies can help doctors prescribe more targeted penicillin antibiotics safely.

Read the report of the ALABAMA trial, link below 👇

13/07/2025

Alzheimer’s disease is the main cause of dementia. It is quickly becoming one of the most expensive, lethal, and burdening diseases of this century.

In general, neurological disorders are the leading cause of disease burden, affecting more than 3 billion people worldwide.

To advance our mission of the best science for better lives, The Lancet has issued a call for papers for a dedicated issue on neurology. Learn more about the research we are looking for ⤵️
https://hubs.li/Q03w_l-p0

💬 A Review on protective genetic variants against Alzheimer’s disease in the comments. The figure is from the Review: Differences between individuals susceptible or resilient to Alzheimer's disease.

11/07/2025

Cerebral palsy (CP) is a lifelong physical disability affecting movement and posture.

Over the past decade, substantial progress in diagnosing, preventing, and managing the condition has transformed treatment approaches. One key discovery is that up to 30% of individuals with CP have a genetic contribution.

A new Seminar in The Lancet highlights the best available evidence to help clinicians address key questions identified by people with lived experience.

Read and share with colleagues; Seminar in the comments 🗨️⤵️

Figure: Diagnosis and management overview

09/07/2025

Gastric cancer affects nearly 1 million people annually, leading to over 650,000 deaths worldwide.

Discover the latest insights on gastric cancer risk factors, treatment approaches, and emerging therapies in a Seminar, link in comments below.

👇Figure: Surgery for gastric cancer.

08/07/2025

Therapies targeting intestinal hormones may help protect the heart and kidneys in patients with type 2 diabetes. However the ways in which they work are not fully understood.

A new Review looks at how these hormones act as a critical link connecting digestion, metabolism, and cardiovascular function, and incretin-based therapies do more than control blood sugar for diabetes patients.

Find out more via the link in the comments below. 👇

📊 Figure: Effects of incretins on digestion and the possible resulting clinical benefits.

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