23/07/2025
Marriage of two AS carriers: without electrophoresis, sickle cell disease condemns their children
It is not enough to love each other to get married. You also need to know each other genetically, because some unions can result in children who are doomed to suffer throughout their lives. This is exactly what can happen when two people who are carriers of the AS gene marry without knowing their compatibility.
Who is an AS person?
An AS person is what is known as a healthy carrier of the sickle cell gene. They show no visible signs of the disease. No pain, no crises, an apparently normal life. But that doesn't mean they are out of danger. The danger is not in their own body, but in the lives of their future children.
The risk of marriage between two AS carriers
When two AS individuals marry and have children, each pregnancy becomes a genetic Russian roulette. With each birth, there is a 25% chance of having a healthy AA child, a 50% chance of having an AS carrier child like the parents, and a 25% chance of having an SS child, i.e., a child with sickle cell disease.
In other words, one in four children will be sick for life, even if the parents are not.
What is everyday life like for an SS child?
An SS sickle cell child is condemned to a life of chronic suffering from early childhood. They experience frequent painful crises, intense bone pain, frequent hospitalizations, missed school days, constant fatigue, growth delays, and live in fear of a stroke or serious infection. They often depend on lifelong medication and frequent transfusions, and their life expectancy is reduced. They didn't ask for this, but they were born with an incurable hereditary disease simply because their parents did not get tested before they got together.
What you need to understand
This is neither fate nor bad luck. It is a logical and avoidable consequence. Two people with AS do not have the right to get together without knowing the risks.
True love also means having the courage to give up a dangerous union to protect the future of your children.
The solution: undergo electrophoresis before planning to marry
This simple blood test will tell you whether you are AA, AS, or SS. It allows you to avoid a genetically high-risk marriage, protect your future children from a life of suffering, and make responsible decisions together, with full knowledge.
Message to young people, engaged couples, and parents
Before saying yes, say I'm checking my status. Before having a child, take the electrophoresis test. Before condemning an innocent life, use common sense.
Because love is not about causing suffering. Love is about protecting, even if it hurts. A test can save a life. Your choice today will determine the fate of your children.
NB:
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