
24/06/2025
Contrary to the common belief that s***m cells "race" to reach the egg and the fastest one wins, scientific studies suggest a far more selective and biologically orchestrated process.
Research in the fields of reproductive biology and cellular signaling indicates that the egg (or oocyte) releases specific chemical substances known as chemoattractants.
These molecules are designed to attract s***m cells by guiding their movement—a process called chemotaxis.
One well-studied chemoattractant is progesterone, which is released by cells surrounding the egg (called cumulus cells).
This chemical not only helps guide s***m but also modulates calcium ion channels in s***m tails, influencing their motility and steering them toward the egg.
The implication is that the egg doesn't passively wait but plays an active role in selecting which s***m reaches it, based on how the s***m responds to these signals.
Moreover, some studies suggest that eggs may preferentially attract s***m from genetically compatible males, potentially maximizing offspring fitness—an idea sometimes referred to as cryptic female choice at the gamete level.
This mechanism explains why not all s***m make it to the egg, and why simply being the "fastest" may not be enough if the s***m does not properly respond to the egg’s chemical cues.