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Herald Scholarly Open Access, 41891 Fraser Downs Ter, Aldie, VA (2026)

05/01/2026

𝐋𝐚𝐫𝐠𝐞-𝐁𝐨𝐫𝐞 𝐂𝐚𝐭𝐡𝐞𝐭𝐞𝐫𝐬 𝐚𝐬 𝐕𝐚𝐬𝐜𝐮𝐥𝐚𝐫 𝐀𝐜𝐜𝐞𝐬𝐬 𝐚𝐫𝐞 𝐢𝐦𝐩𝐨𝐫𝐭𝐚𝐧𝐭, 𝐛𝐮𝐭 𝐧𝐞𝐞𝐝 𝐦𝐚𝐧𝐲 𝐈𝐦𝐩𝐫𝐨𝐯𝐞𝐦𝐞𝐧𝐭𝐬

📌Source: Journal of Angiology & Vascular Surgery (ISSN: 2572-7397)

✅The introduction of large-bore catheters with the Seldinger technique into the vena cava superior via the internal jugular vein is superior to the puncturing technique of the subclavian or femoral veins.
✅Complications and adverse effects were seen by the puncturing of the internal jugular vein, such as bleeding, faulty punctures, hemothorax, thrombosis, faults in catheter material, and infections. ✅Thrombosis, infections, and stenosis are among the most frequent side effects associated with the handling of the catheters by attending staff and with blood-contacting catheters.
✅Besides surface treatment processes, such as ion implantation, ion beam-assisted deposition, and microdomain structures, other new catheter technologies and catheter materials are necessary to mitigate the mentioned complications and the high costs of the catheter-related infections.

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04/01/2026

𝐓𝐚𝐫𝐠𝐞𝐭𝐢𝐧𝐠 𝐌𝐮𝐥𝐭𝐢𝐩𝐥𝐞 𝐇𝐚𝐥𝐥𝐦𝐚𝐫𝐤𝐬 𝐨𝐟 𝐀𝐠𝐢𝐧𝐠 𝐰𝐢𝐭𝐡 𝐏𝐫𝐨𝐱𝐲𝐥𝐚𝐧𝐞, 𝐆𝐢𝐧𝐤𝐠𝐨 𝐛𝐢𝐥𝐨𝐛𝐚 𝐥𝐞𝐚𝐟 𝐞𝐱𝐭𝐫𝐚𝐜𝐭 𝐚𝐧𝐝 𝐍𝐢𝐚𝐜𝐢𝐧𝐚𝐦𝐢𝐝𝐞 𝐈𝐦𝐩𝐫𝐨𝐯𝐞𝐬 𝐇𝐞𝐚𝐥𝐭𝐡𝐬𝐩𝐚𝐧 𝐛𝐲 𝐑𝐞𝐯𝐞𝐫𝐬𝐢𝐧𝐠 𝐭𝐡𝐞 𝐀𝐠𝐞𝐝 𝐒𝐤𝐢𝐧 𝐏𝐡𝐞𝐧𝐨𝐭𝐲𝐩𝐞

📌𝑆𝑜𝑢𝑟𝑐𝑒: 𝐽𝑜𝑢𝑟𝑛𝑎𝑙 𝑜𝑓 𝐶𝑙𝑖𝑛𝑖𝑐𝑎𝑙 𝐷𝑒𝑟𝑚𝑎𝑡𝑜𝑙𝑜𝑔𝑦 & 𝑇ℎ𝑒𝑟𝑎𝑝𝑦

Aging is an intrinsic and inevitable process, characterized by a progressive decline in physiological functions. While unavoidable, it is nonetheless modifiable, a fundamental principle of the longevity approach. Unlike conventional anti-aging strategies, longevity targets the root causes of aging at the cellular level to sustainably maintain skin health and improve skin appearance. In this context, we have developed a specific combination of Proxylane, Ginkgo biloba leaf extract, and niacinamide, designed to target five key hallmarks of skin .

👉To demonstrate its efficacy, we used a skin model reconstructed from aged donor cells, faithfully reproducing an aged phenotype. Our study revealed that this combination effectively reversed the aged phenotype. More specifically, it increased epidermal thickness, drastically reduced the presence of senescent cells in the epidermis, restored autophagy, and stimulated the expression of essential proteins. These included collagens IV, VII, and perlecan, for strengthening the dermo-epidermal junction, as well as collagen I, elastin, and fibrillin, for the dermal extracellular matrix. The combined treatment showed superior results compared to each active ingredient taken individually, highlighting the value of simultaneously targeting multiple pathwaysof aging.

👉These results clearly demonstrate in vitro the effectiveness of our combination in mitigating age-related issues by addressing five key hallmarks of aging, thus confirming its potential to further improve skin visible aging signs as part of a comprehensive longevity strategy.

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02/13/2026

𝐄𝐯𝐚𝐥𝐮𝐚𝐭𝐢𝐧𝐠 𝐂𝐨𝐧𝐬𝐭𝐫𝐮𝐜𝐭 𝐀𝐥𝐢𝐠𝐧𝐦𝐞𝐧𝐭 𝐨𝐟 𝐭𝐡𝐞 𝐏𝐍 𝐂𝐨𝐦𝐩𝐫𝐞𝐡𝐞𝐧𝐬𝐢𝐯𝐞 𝐏𝐫𝐞𝐝𝐢𝐜𝐭𝐨𝐫 𝐚𝐧𝐝 𝐭𝐡𝐞 𝐍𝐂𝐋𝐄𝐗-𝐏𝐍 𝐓𝐞𝐬𝐭 𝐏𝐥𝐚𝐧

📌Source: Journal of Practical & Professional Nursing
📌Published Date: Feb 06, 2026

✅Background: In order for nurse educators to ensure students are prepared for entry-level nursing practice nursing curriculum, assessments and learning activities should incorporate the NCLEX domains and client care needs categories. The CP exam is deliberately designed using the NCLEX-PN test plan to include clinical judgement, all domains and client needs categories in order to provide a comprehensive assessment of students NCLEX readiness.

✅Method: A confirmatory factor analysis was used to analyze exam scores from over 4,547 nursing students to evaluate the PN Comprehensive Predictor hypothesized structure alignment to the NCLEX-PN blueprint categories and subcategories.

✅Results: The results of this study provided evidence that the Comprehensive Predictor assessment data fits the NCLEX-PN blueprint. The factor analysis suggests that nursing competence, as reflected in test performances, aligns with the NCLEX-PN blueprint categories and subcategories.

✅Conclusion: Consistent with RN , the findings provided robust evidence of construct validity for the PN CP total score and sub-scores as meaningful indicators of entry-level nursing competence, which has implications for educational strategies and assessment practices in nursing education.

👉 bit.ly/3OH2rta

02/10/2026

𝐃𝐨𝐠𝐬 𝐚𝐬 𝐚 𝐓𝐡𝐞𝐫𝐚𝐩𝐞𝐮𝐭𝐢𝐜 𝐌𝐞𝐝𝐢𝐮𝐦: 𝐔𝐧𝐢𝐯𝐞𝐫𝐬𝐢𝐭𝐲 𝐒𝐭𝐮𝐝𝐞𝐧𝐭𝐬’ 𝐄𝐱𝐩𝐞𝐫𝐢𝐞𝐧𝐜𝐞𝐬 𝐨𝐟 𝐓𝐡𝐞𝐫𝐚𝐩𝐲 𝐃𝐨𝐠𝐬 𝐨𝐧 𝐂𝐚𝐦𝐩𝐮𝐬

📌Source: Journal of Alternative Complementary & Integrative Medicine

University students experience increased stress during examination periods, detrimentally impacting academic performance and mental wellbeing. Although universities offer counselling and wellbeing services, there is a growing demand for innovative, non-traditional strategies that complement traditional supports.

☘️This study explored the influence of therapy dogs on students, across multiple university campuses during examination periods, examining how interactions with the dogs affected students’ perceptions of their health, social behaviours, and stress levels.

☘️A qualitative design was used, involving observations of student behaviour during dog interactions and analysis of comments posted on social media promoting the program. Content analysis identified major categories and derived meaning from the data.

☘️Findings reveal that therapy dogs distract students from stressful thoughts, foster social connection, and build trusting interactions that encourage openness. The program also appeared to strengthen students’ sense of being cared for by the university, suggesting that Animal-Assisted Therapy may serve as a complementary, integrative approach to supporting student wellbeing.

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02/02/2026

𝐓𝐡𝐞 𝐑𝐨𝐥𝐞 𝐨𝐟 𝐒𝐥𝐨𝐰 𝐆𝐚𝐢𝐭 𝐒𝐩𝐞𝐞𝐝 𝐢𝐧 𝐂𝐨𝐠𝐧𝐢𝐭𝐢𝐯𝐞 𝐃𝐞𝐜𝐥𝐢𝐧𝐞 𝐚𝐦𝐨𝐧𝐠 𝐀𝐠𝐢𝐧𝐠 𝐖𝐨𝐦𝐞𝐧: 𝐀 𝐒𝐲𝐬𝐭𝐞𝐦𝐚𝐭𝐢𝐜 𝐑𝐞𝐯𝐢𝐞𝐰

📍𝑆𝑜𝑢𝑟𝑐𝑒: 𝐽𝑜𝑢𝑟𝑛𝑎𝑙 𝑜𝑓 𝐺𝑒𝑟𝑜𝑛𝑡𝑜𝑙𝑜𝑔𝑦 & 𝐺𝑒𝑟𝑖𝑎𝑡𝑟𝑖𝑐 𝑀𝑒𝑑𝑖𝑐𝑖𝑛𝑒
📍𝑃𝑢𝑏𝑙𝑖𝑠ℎ𝑒𝑑 𝐷𝑎𝑡𝑒: 𝐹𝑒𝑏 03, 2026

The prevalence of Alzheimer’s disease and related dementias are increasing at an alarming rate, with projections estimating that by 2060, approximately 13.8 million adults aged 65 years and older in the U.S. will be affected by one or both. Among the many symptoms associated with cognitive decline, gait impairment is one that significantly affects functional independence and mobility.

✅Methods: A systematic review was conducted to analyze 49 peer-reviewed studies using the Covidence systematic review software and adhering to PRISMA guidelines. The selected articles examined variables related to gait speed, and cognition. Participants were assessed through validated neurocognitive and mobility measures, including the MoCA and Dynamic Gait Index.

✅Results: A significant negative correlation was identified between usual walking speed and age. This trend was particularly pronounced in women, in whom a significant negative association between MoCA scores and age (P = -0.019) was observed, suggesting an increased susceptibility to cognitive deterioration with advancing age.

✅Conclusion: These findings underline the sex-specific nature of the relationship between gait speed and cognitive function, highlighting increased vulnerability in aging women. The decline in mobility and cognition observed in this population underscores the urgency of developing targeted interventions that integrate physical and cognitive rehabilitation strategies.

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01/19/2026

𝐔𝐬𝐞 𝐨𝐟 𝐚 𝐍𝐨𝐯𝐞𝐥 𝐑𝐞𝐬𝐩𝐢𝐫𝐚𝐭𝐨𝐫𝐲 𝐌𝐮𝐬𝐜𝐥𝐞 𝐓𝐫𝐚𝐢𝐧𝐢𝐧𝐠 𝐃𝐞𝐯𝐢𝐜𝐞 𝐈𝐧𝐜𝐫𝐞𝐚𝐬𝐞𝐬 𝐏𝐮𝐥𝐦𝐨𝐧𝐚𝐫𝐲 𝐕𝐢𝐭𝐚𝐥 𝐂𝐚𝐩𝐚𝐜𝐢𝐭𝐲 𝐢𝐧 𝐑𝐞𝐚𝐥-𝐖𝐨𝐫𝐥𝐝 𝐀𝐩𝐩𝐥𝐢𝐜𝐚𝐭𝐢𝐨𝐧

📍Source: Journal of Pulmonary Medicine & Respiratory Research
📍Published Date: Dec 30, 2025

✅COPD (chronic obstructive pulmonary disease) is a condition caused by inflammatory damage and weakening of the lungs and respiratory muscles which limits airflow and gas exchange in the lung alveoli. Dynamic hyperinflation present in COPD is associated with an overload of respiratory muscles, which perpetuates the cycle of events. Symptoms of COPD include trouble breathing, cough and wheezing. Inspiratory muscle weakness is frequently found along with significant exercise limitation, deconditioning, decrease in athletic performance, and quality of life.

✅The best-known risk factors in developing COPD are exposure to to***co smoke, although other factors such as environmental pollution or exposure to biomass combustion, together with individual predisposition, have also been correlated. Emphysema and chronic bronchitis are the two most common types of COPD. These two conditions usually occur together and can vary in severity in COPD. Currently, COPD is one of the first causes of worldwide morbimortality.

✅Although COPD is a progressive condition, it is preventable and treatable so that quality of life is increased, and with appropriate management, the risk of COPD associated conditions, such as heart disease and lung cancer can be minimized. In the 1980s, highlighted inspiratory muscle weakness in COPD patients and the potential benefits of targeted training. Respiratory exercise devices that employ inspiratory muscle training (IMT) are widely used to improve respiratory capacity in individuals with COPD and other respiratory diseases to improve respiratory function and quality of life. Respiratory rehabilitation (RR) as part of IMT is postulated as being the most cost-effective treatment strategy with widely accepted, reduction in hospital admissions and mortality in patients.

✅The Airofit Pro breathing trainer has been designed as a novel IMT device to improving lung capacity among its users and when used as part of a respiratory rehabilitation program, may have significant benefit in the treatment of COPD. A real-world evidential study in the use of the Airofit Pro breathing trainer has been performed in a cohort of more than 16,000 self-selected subjects over a five-year period of enrollment with highly promising respiratory benefits including increases in lung capacity that could significantly benefit individuals suffering with COPD.

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👉 https://www.heraldopenaccess.us/openaccess/use-of-a-novel-respiratory-muscle-training-device-increases-pulmonary-vital-capacity-in-real-world-application

01/06/2026

𝐅𝐞𝐞𝐥𝐢𝐧𝐠 𝐚𝐬 𝐈𝐧𝐭𝐞𝐫𝐯𝐞𝐧𝐭𝐢𝐨𝐧: 𝐀 𝐏𝐞𝐫𝐬𝐩𝐞𝐜𝐭𝐢𝐯𝐞 𝐨𝐧 𝐄𝐦𝐨𝐭𝐢𝐨𝐧𝐚𝐥–𝐒𝐨𝐦𝐚𝐭𝐢𝐜 𝐀𝐩𝐩𝐫𝐨𝐚𝐜𝐡𝐞𝐬 𝐭𝐨 𝐂𝐡𝐫𝐨𝐧𝐢𝐜 𝐏𝐚𝐢𝐧 𝐌𝐚𝐧𝐚𝐠𝐞𝐦𝐞𝐧𝐭
📍Source: Journal of Alternative Complementary & Integrative Medicine
📍Published Date: Dec 31, 2025

✅Chronic pain is rarely a purely physical problem. It is shaped by stress physiology, emotional learning and memory, and the way the nervous system predicts and protects.

✅Evidence from mindbody and movement-based interventions suggests that combining embodied attention with gentle movement can reduce pain and disability for some patients, although effect sizes vary and mechanisms remain under investigation.

✅In a recent pilot study in a yoga context, HeartSpeak - an emotional-somatic release method - was associated with meaningful within-class reductions in subjective pain in people with persistent pain.

✅This perspective outlines why integrating feeling-based work into movement may be clinically relevant, how implicit learning contributes to persistent pain, and why emotional-somatic approaches warrant more rigorous study within chronic pain management.

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12/24/2025

📍Published Date: Dec 17, 2025
📍Journal of Reproductive Medicine Gynaecology & Obstetrics

We recorded 3436 deliveries during the collection period, including 307 cases of placental abruption, i.e. a frequency of placental abruption of 8.93%. Among these deliveries, there were 269 primiparous women with 50 patients admitted for placental abruption, i.e. a frequency of placental abruption in primiparous women of 18.6%.

Placental abruption remains a major obstetric emergency, particularly in primiparous women, and requires close monitoring of identifiable risk factors.

👉This study highlights that the absence of prenatal follow-up and inadequate management of risk factors considerably increase the probability of occurrence of this pathology. Maternal-fetal prognosis depends directly on the speed of diagnosis and management. It is essential to strengthen prenatal monitoring to prevent complications associated with placental abruption and improve outcomes for mothers and newborns.

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12/16/2025

𝐑𝐞𝐬𝐢𝐥𝐢𝐞𝐧𝐭 𝐛𝐲 𝐃𝐞𝐬𝐢𝐠𝐧: 𝐁𝐮𝐢𝐥𝐝𝐢𝐧𝐠 𝐀𝐝𝐚𝐩𝐭𝐢𝐯𝐞 𝐂𝐚𝐩𝐚𝐜𝐢𝐭𝐲 𝐢𝐧 𝐆𝐥𝐨𝐛𝐚𝐥 𝐔𝐧𝐢𝐯𝐞𝐫𝐬𝐢𝐭𝐲 𝐄𝐝𝐮𝐜𝐚𝐭𝐢𝐨𝐧

✅Universities face multifaceted risks that threaten academic, financial and operational integrity.

✅This paper develops a comprehensive resilience framework for higher education institutions, identifies key risk domains and offers strategic recommendations for global implementation.

✅Drawing on international frameworks and institutional case studies, the research emphasises integrated governance, adaptive capacity and proactive planning to sustain core missions during disruption.

✅Methods combined qualitative document analysis and expert consultations to synthesise resilience domains, validate framework components and derive actionable recommendations.

✅Findings highlight governance, integrated risk management, digital and cyber resilience, equity and community engagement and academic continuity as core domains.

✅Recommendations include embedding resilience indicators into executive reporting, establishing cross-functional resilience teams, routine horizon scanning, scalable blended learning infrastructure and expanded psychological resilience programs.

✅The framework aims to guide universities in embedding resilience into strategic architecture to navigate uncertainty and support societal stability.

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12/09/2025

𝐑𝐞𝐥𝐚𝐭𝐢𝐨𝐧 𝐛𝐞𝐭𝐰𝐞𝐞𝐧 𝐌𝐚𝐭𝐞𝐫𝐧𝐚𝐥 𝐕𝐢𝐭𝐚𝐦𝐢𝐧 𝐃 𝐂𝐨𝐧𝐜𝐞𝐧𝐭𝐫𝐚𝐭𝐢𝐨𝐧 𝐝𝐮𝐫𝐢𝐧𝐠 𝐓𝐡𝐢𝐫𝐝 𝐓𝐫𝐢𝐦𝐞𝐬𝐭𝐞𝐫 𝐚𝐧𝐝 𝐌𝐚𝐭𝐞𝐫𝐧𝐚𝐥 𝐚𝐧𝐝 𝐍𝐞𝐨𝐧𝐚𝐭𝐚𝐥 𝐇𝐞𝐚𝐥𝐭𝐡 𝐎𝐮𝐭𝐜𝐨𝐦𝐞𝐬

✅Background: Vitamin D is a key nutritional factor for maintenance of maternal and fetal . Fetal vitamin D acquisition is entirely dependent on the availability of the mother’s 25-hydroxyvitamin D, VitaminD regulates parathyroid hormone level and increases calcium absorption, critical factors in fetal development.

✅Objective: Vitamin D deficiency occurs frequently in pregnancy and may lead to preeclampsia, gestational diabetes, postpartum depression, and stillbirth. Therefore, it is necessary to establish the risk factors for during pregnancy to enable a preliminary and predictable diagnosis of vitamin D deficiency and its complications.

✅Materials and Methods: This cross-sectional was conducted between February 2017 and January 2019 in a referral tertiary hospital in Beijing, China. All data were extracted from the hospital’s patient information system. Vitamin D deficiency was defined as total serum 25-hydroxyvitamin-D concentration less than 20 ng/ml, whereas concentrations between 20 and 30 ng/ml were classified as vitamin D insufficiency.

✅Results: We included 306 participants with singleton pregnancies. The prevalence of vitamin D deficiency was 57.51% (176/306). A significant correlation was found between vitamin D concentration and the gestational week of delivery (P ≤0.001).

✅Conclusion: Vitamin D deficiency is a common phenomenon among pregnant women in the Chinese mainland, and the concentration of vitamin D in their bodies is significantly correlated with the progress of .

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📊Figure: Linear relationship between serum 25(OH)-D and birth week.

12/05/2025

Latest research by Christian Chess, et al. RUH Bath
"𝐎𝐩𝐭𝐢𝐦𝐢𝐬𝐢𝐧𝐠 𝐃𝐢𝐬𝐭𝐚𝐥 𝐅𝐞𝐦𝐨𝐫𝐚𝐥 𝐅𝐫𝐚𝐜𝐭𝐮𝐫𝐞𝐬 𝐢𝐧 𝐎𝐥𝐝𝐞𝐫 𝐀𝐝𝐮𝐥𝐭𝐬: 𝐀𝐧 𝐌𝐃𝐓 𝐚𝐧𝐝 𝐎𝐫𝐭𝐡𝐨𝐠𝐞𝐫𝐢𝐚𝐭𝐫𝐢𝐜 𝐌𝐨𝐝𝐞𝐥" make a difference in the lives of elderly patients.

👉Distal Femoral Fractures (DFFs) are an often overlooked and under-appreciated source of morbidity and mortality in elderly patients. They present a high level of surgical complexity, with multiple treatment options available (nailing, plating, arthroplasty and combination), compounded by challenging perioperative optimisation and frequently inadequate system-level support.

✅The typical DFF patient is elderly, frail and multimorbid, presenting with osteoporosis, sarcopenia and managing significant polypharmacy alongside pre-existing functional dependency.

✅This profound vulnerability is starkly reflected in clinical outcomes: Loosen et al., reported 64% perioperative morbidity and a 26-35% one-year mortality (median age 86.5) following treatment for DFFs, with 62% of previously independent, home-dwelling patients failing to return home and requiring long-term residential care.

✅Clinically and demographically, DFFs mirror hip fractures, yet historically have lacked the same structured care pathways with orthogeriatric input, national audit, and aligned financial incentives, resulting in preventable disparities in outcomes. Encouragingly, this landscape is changing.

✅NHS England has extended the Best Practice Tariff (BPT) to distal femoral fractures, and the National Hip Fracture Database (NHFD) has begun explicit case capture of DFFs.

✅This article presents a Formalised Multidisciplinary Team (MDT) pathway for the assessment and management of fragility distal femoral fractures.

👉By standardising care across pre-operative, intraoperative, and postoperative phases, the approach closes performance gaps, integrates medical and surgical optimisation, and delivers measurable improvements in clinical outcomes.

Find out more about Distal Femoral Fractures (DFFs) via the link in comments 💬

📊Figure: Radiograph of a left distal femoral plate fixation.
(a) - Anterior View. (b) - Lateral View.

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