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American Registry of Pathology Press

Publisher of the AFIP/ARP fascicles

10/18/2025

More from arppress.org/books/book/68:
Cribriform-morular thyroid carcinoma (previously considered a PTC subtype, but frequently negative for thyroglobulin and PAX8) is characterized by an intimate admixture of cribriform, follicular, papillary, trabecular, and solid patterns of growth, with round squamoid structures known as morules.

10/14/2025

Another PTC variant as discussed in arppress.org/books/book/68:
Warthin-like PTC is composed of papillae lined by oncocytic cells with PTC nuclei and a prominent lymphocytic infiltrate in the papillary core, reminiscent of the salivary gland tumor. It is questioned whether this subtype is a separate entity or just represents other known subtypes with a heavy lymphoid infiltrate.

10/11/2025

Another papillary thyroid carcinoma (PTC) subtype:
Columnar cell PTC (0.2% of PTCs) is characterized by columnar cells with prominent nuclear pseudostratification. The pseudostratification and lack of abundant eosinophilic cytoplasm can help distinguish from the tall cell variant (see our last post).

10/08/2025

More from arppress.org/books/book/68:
Papillary thyroid carcinoma has many variants including tall cell type, characterized by cell height at least 2x the width (>30%), often eosinophilic cytoplasm, and more aggressive clinical behavior.

09/26/2025

The next edition of Tumors of the Central Nervous System is here!
Impactful new discoveries, evolving diagnostic classifications, and rapid technical advances have reshaped the field. Having this essential atlas is key for supporting every practicing diagnostic pathologist. www.arppress.org

09/25/2025

More from arppress.org/books/book/68:
Medullary thyroid carcinoma is a malignant thyroid tumor composed of cells showing evidence of C-cell differentiation. 25-30% are associated with hereditary germline RET mutations.

09/18/2025

More from arppress.org/books/book/68:
Hyalinizing trabecular tumor is characterized by fusions of the GLIS genes (PAX8::GLIS1 and PAX8::GLIS3), and almost all have benign behavior. This tumor demonstrates a peculiar membranous staining pattern for ki-67 (MIB-1 monoclonal antibody) at room temperature; membranous staining is often absent using fully automated stains.

09/15/2025

From arppress.org/books/book/68:
Noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) is as the name describes (we love that) and has an extremely low malignant potential. True papillae should be absent/scarce (

09/04/2025

It's September, and Tumors of the Thyroid and Parathyroid Glands (arppress.org/books/book/68) has joined our series 5 fascicles!
Solid cell nests are remnants of the ultimobranchial bodies and are found in 3% of routinely examined thyroid glands. They often have a squamoid appearance.

09/01/2025

This Labor Day, get 20% OFF sitewide at ARPPress.org. It's the perfect opportunity to get caught up with the latest fascicles. Use code: Labor Day-hd4kenh0

08/29/2025

More from arppress.org/books/book/67:
Paragangliomas are neural crest-derived tumors differentiating into paraganglion cells; they have classic nested architecture ("Zellballen"), occasionally with prominent, hyalinized stroma.

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