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American Registry of Pathology Press

Publisher of the AFIP/ARP fascicles

07/07/2025

A preview from the new Series 5 fascicle: Tumors of the Upper Aerodigestive Tract, Ear, and Jaw (arppress.org/books/book/67):
Granular cell tumor is a benign neuroectodermal tumor that can be accompanied by overlying pseudoepitheliomatous hyperplasia (second image set; not to be mistaken for squamous cell carcinoma). More than 50% of cases of granular cell tumor involve the head & neck!

06/17/2025

More from arppress.org/books/book/42:
Diverticula can affect the vermiform appendix (incidence

06/13/2025

More on non-neoplastic GI (arppress.org/books/book/42):
Esophageal gastric heterotopias are detected in approximately 12% of adults (M = F) who undergo upper endoscopy. Most are asymptomatic, although large rests of oxyntic-type mucosa can produce enough acid to cause signs/symptoms.

06/10/2025

More from arppress.org/books/book/42:
Esophageal duplication cysts are congenital cysts that contain a muscular wall and various mucosal elements that may or may not have a connection to the lumen. These can bulge into the lumen and produce endoscopically apparent semispherical impressions.

06/06/2025

More on non-neoplastic gastrointestinal (arppress.org/books/book/42):
Melanosis coli is associated with senna-containing compounds and other plant glycosides, and is usually an incidental finding during colonoscopy. It's less pronounced in adenomas (image A).

06/03/2025

More on non-neoplastic gastrointestinal (arppress.org/books/book/42):
Actinomyces israelii (a gram-positive, anaerobic, filamentous bacterium) is part of the normal intestinal flora, and can be an occasional cause of acute appendicitis. Yellow or brown "sulfur granules" (seen histologically as radially arranged Splendore-Hoeppli protein) are detected in 50% of cases.

05/28/2025

More on non-neoplastic GI pathology (arppress.org/books/book/42):
Acquired pyloric stenosis results in gastric outlet obstruction, most often due to healed gastric or duodenal ulcers, neoplastic infiltration by carcinoma or lymphoma, or postoperative adhesions.

05/21/2025

We're now revisiting our series 5 fascicle "Non-Neoplastic Disorders of the Gastrointestinal Tract" (arppress.org/books/book/42):
A duplication cyst is a tubular or cystic structure (with all layers of the intestinal wall) that is contiguous with the small bowel or colon; it has a prevalence of 0.0002% in the general population.

05/14/2025

From arppress.org/books/book/36:
Abruption is the premature separation of the placenta from the decidua by maternal hemorrhage (after 20 weeks), usually due to vascular or decidual injury due to hypertension, inflammation, or trauma.

05/06/2025

More on placenta (arppress.org/books/book/36):
Decidual arteriopathy is associated with maternal hypertensive disorders; the most common form consists of fibrinoid necrosis of the vascular wall, frequently with a mononuclear cell perivasculitis.

04/29/2025

More on placentas (arppress.org/books/book/36):
Microscopic chorionic pseudocysts (aka chorionic membrane microcysts) are small eosinophilic fluid-filled pseudocysts in the chorion laeve, thought to be secretory or degenerative in nature.

04/28/2025

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