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American Registry of Pathology Press

Publisher of the AFIP/ARP fascicles

11/27/2025

Your generosity, whether personal or institutional, is an investment in the foundational knowledge of pathology. This giving season, we humbly ask for your support. https://arppress.org/pages/donate

11/24/2025

Continuing from arppress.org/books/book/69:
Pineoblastoma is a high-grade embryonal neoplasm with round blue cell cytomorphology centered in the pineal gland (a CNS WHO grade 4); this tends to affect children (1st two decades) but may develop at any age.

11/13/2025

From the new "Tumors of the Central Nervous System" fascicle (arppress.org/books/book/69):
Ependymomas demonstrates both glial and epithelial differentiation, and sharp circumscription is a hallmark. Morphologic patterns can vary widely! Patterns that are not their own subtype include cellular (A), clear cell (B), tanycytic (C), and papillary (D).

11/05/2025

Happy International Pathology Day! 🔬
The American Registry of Pathology (ARP) celebrates pathologists and laboratory professionals worldwide. Your precision, education, and innovation are the foundation of quality healthcare that saves lives every day. Don't miss 20% off ARP Fascicles this week (Code: NPW2025-tofobtwb). Shop: arppress.org

11/03/2025

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10/18/2025

More from arppress.org/books/book/68:
Cribriform-morular thyroid carcinoma (previously considered a PTC subtype, but frequently negative for thyroglobulin and PAX8) is characterized by an intimate admixture of cribriform, follicular, papillary, trabecular, and solid patterns of growth, with round squamoid structures known as morules.

10/14/2025

Another PTC variant as discussed in arppress.org/books/book/68:
Warthin-like PTC is composed of papillae lined by oncocytic cells with PTC nuclei and a prominent lymphocytic infiltrate in the papillary core, reminiscent of the salivary gland tumor. It is questioned whether this subtype is a separate entity or just represents other known subtypes with a heavy lymphoid infiltrate.

10/11/2025

Another papillary thyroid carcinoma (PTC) subtype:
Columnar cell PTC (0.2% of PTCs) is characterized by columnar cells with prominent nuclear pseudostratification. The pseudostratification and lack of abundant eosinophilic cytoplasm can help distinguish from the tall cell variant (see our last post).

10/08/2025

More from arppress.org/books/book/68:
Papillary thyroid carcinoma has many variants including tall cell type, characterized by cell height at least 2x the width (>30%), often eosinophilic cytoplasm, and more aggressive clinical behavior.

09/26/2025

The next edition of Tumors of the Central Nervous System is here!
Impactful new discoveries, evolving diagnostic classifications, and rapid technical advances have reshaped the field. Having this essential atlas is key for supporting every practicing diagnostic pathologist. www.arppress.org

09/25/2025

More from arppress.org/books/book/68:
Medullary thyroid carcinoma is a malignant thyroid tumor composed of cells showing evidence of C-cell differentiation. 25-30% are associated with hereditary germline RET mutations.

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