12/30/2025
This comprehensive educational video explains Medication-Assisted Treatment (MAT) as an evidence-based approach to treating Opioid Use Disorder (OUD). Learn about the three FDA-approved medications—buprenorphine, methadone, and naltrexone—and how they work in combination with counseling and behavioral therapies. MAT is shown to significantly improve treatment retention, reduce cravings and withdrawal symptoms, and lower the risk of overdose.
Video Topics & Key Terms:
The neurobiology of OUD and how MAT works Buprenorphine (Suboxone, Sublocade)
Methadone (Opioid Treatment Programs - OTPs)
Naltrexone (Vivitrol)
The importance of counseling and behavioral therapy
Reframing MAT as recovery, not substitution
00:00Introduction: What is Medication-Assisted Treatment (MAT)?
01:15The Science: Understanding Opioid Use Disorder (OUD)
02:50The Role of Counseling and Behavioral Therapy
04:30Medication Focus: Buprenorphine and How it Works
07:00Medication Focus: Methadone and OTP Requirements
09:45Medication Focus: Naltrexone and Antagonist Therapy
12:10Comparing the Medications: Agonist vs. Antagonist
14:30MAT Outcomes: Retention, Overdose Reduction, and Recovery
16:00Conclusion and Call to Action/Resources