09/07/2026
Diagnoses of alpha-gal syndrome, a severe, tick-borne allergy, are rising throughout the Mississippi River basin. Expanding white-tailed deer populations, climate change and massive historical shifts in land use and development have fueled the rise of this mysterious illness.
Arkansas is a bellwether for much of the country. The state had 1,331 suspected cases in the first half of 2025. That figure has nearly doubled over the same period this year.
As the condition spreads, researchers are still unraveling the disease, public health agencies are struggling to track it, and there’s little federal funding or coordination driving efforts forward. But that may be changing as awareness spreads. The challenge now isn’t just understanding the disease; it’s figuring out how to stop it. Arkansas researchers and residents may hold some clues.
Story by Arkansas Times’s Elizabeth Cline
As an epicenter of a mysterious tick-borne illness, The Natural State offers a window into what’s driving its rise, how it functions — and what comes next.