10/19/2021
Liver-on-chip models mimic in vivo livers, liver disease
Liver-on-chip models mimic in vivo livers, liver disease
Fabricating organs to better understand the chemical reactions happening within organs and communication between organs.
APL Bioengineering
- Home
- United States
- Melville, NY
- APL Bioengineering
APL Bioengineering is devoted to research at the intersection of biology, physics, and engineering.
The journal publishes high-impact manuscripts specific to the understanding and advancement of physics and engineering of biological systems. The newest member of the Applied Physics Letters family and the sister journal to APL Materials and APL Photonics. APL Bioengineering is devoted to research at the intersection of Biology, Physics, and Engineering. From drug delivery and tissue engineering t
o biosensors and biomedical devices, APL Bioengineering is the new home for the bioengineering and biomedical research communities. APL Bioengineering open access ensures your research is available any time, any place and being open access, meets funder mandates everywhere.
10/08/2021
High-throughput screening of nanoparticles in drug delivery
High-throughput combinatorial synthesis and screening is a powerful strategy to screen drug delivery systems with enhanced targeting and release, accelerating in vivo testing and clinical translation
The use of pharmacologically active compounds to manage and treat diseases is of utmost relevance in clinical practice. It is well recognized that spatial-temporal control over the delivery of thes...
10/07/2021
Better models could improve liver cancer treatment
Better models could improve liver cancer treatment
Understanding the microenvironment of tumors and using in vitro models that properly reflect it will improve the development of immunotherapies for liver cancer.
09/14/2021
High-throughput nanoparticle screening propels RNA drug delivery to clinical settings
High-throughput nanoparticle screening propels RNA drug delivery to clinical settings
Decades of work culminate in the first generation of RNA-based therapies, look to push their clinical utility further
07/23/2021
Bleak Cyborg Future from Brain-Computer Interfaces if We're Not Careful - AIP Publishing LLC
Bleak Cyborg Future from Brain-Computer Interfaces if We're Not Careful - AIP Publishing LLC
Link to article: Mind the gap: State-of-the-art technologies and applications for EEG-based brain-computer interfaces DOI: 10.1063/5.0047237...
07/20/2021
Surveying the landscape of model livers assesses their role in drug development
Surveying the landscape of model livers assesses their role in drug development
An examination of case studies from the biopharmaceutical industry demonstrates how commercially available in vitro human liver models are used in drug development.
07/09/2021
Skin-on-a-chip emerging as alternative to animal testing and static drug screening platforms
Skin-on-a-chip emerging as alternative to animal testing and static drug screening platforms
Mimicking skin as a dynamic organ, microfluidic-based technology enables cost effective and high throughput testing.
06/08/2021
Surface engineering at the nanoscale: A way forward to improve coronary stent efficacy
Simple nanoscale surface engineering of metallic coronary stents can offer an efficacious and cost-effective alternative to drug eluting stents to prevent neointimal hyperplasia and restenosis.
Coronary in-stent restenosis and late stent thrombosis are the two major inadequacies of vascular stents that limit its long-term efficacy. Although restenosis has been successfully inhibited throu...
05/25/2021
Biofabrication of tissue engineering vascular systems
This review outlines the design requirements of Tissue Engineered Vascular System, and explores the advances in biofabrication methods and biomaterials with special focus on in-vitro applications of TEVS for disease modeling.
Cardiovascular disease (CVD) is the leading cause of death among persons aged 65 and older in the United States and many other developed countries. Tissue engineered vascular systems (TEVS) can ser...
05/24/2021
Functional bionanomaterials for cell surface engineering in cancer immunotherapy
This review summarizes recently used cell surface engineering techniques with functional bionanomaterials for cancer immunotherapy and comments future perspectives on the development of cell surface engineering.
The cell surface is the forward position in cancer immunotherapy, with surface ligand and receptor interactions between various cells for determining immune privilege or recognition. Therefore, cel...
05/14/2021
Mechanotransduction assays for neural regeneration strategies: A focus on glial cells
Engineered systems have taken a step forward to design platforms imparting diverse mechanical stresses to with relevance of the tissues.
Nanyang Technological University, Singapore
Glial cells are mechanosensitive, and thus, engineered systems have taken a step forward to design mechanotransduction platforms in order to impart diverse mechanical stresses to cells. Mechanical ...
05/11/2021
Using biofabricated tissue-engineered vascular systems to study cardiovascular disease
Using biofabricated tissue-engineered vascular systems to study cardiovascular disease
Tissue-engineered vascular systems that are biofabricated using novel materials can serve to model certain heart diseases, such as atherosclerosis, and to test drug therapies for these diseases.
05/04/2021
Functional bionanomaterials help optimize surface engineering to improve cancer immunotherapy
Functional bionanomaterials help optimize surface engineering to improve cancer immunotherapy
A review summarizes using bionanomaterials for cell surface engineering – both ex vivo and in vivo – in cancer immunotherapy.
04/28/2021
Label-free microfluidic sorting of microparticles
Microfluidics is a burgeoning field with numerous biomedical applications. In this review, the authors summarize progress and challenges in label-free microfluidic sorting of cells and microparticles.
Massive growth of the microfluidics field has triggered numerous advances in focusing, separating, ordering, concentrating, and mixing of microparticles. Microfluidic systems capable of performing ...
04/13/2021
Engineering in vitro human neural tissue analogs by 3D bioprinting and electrostimulation
This article provides an overview of engineering neural tissues by 3D bioprinting. The authors promulgate “next generation” tissue building with electrical stimulation to enhance printed tissue formation and maturation.
There is a fundamental need for clinically relevant, reproducible, and standardized in vitro human neural tissue models, not least of all to study heterogenic and complex human-specific neurologica...
04/09/2021
Harnessing adipose stem cell diversity in regenerative medicine
This review discusses heterogeneity in the adipose organ, how heterogeneity translates into depot-specific stem cell features and how atypical populations may be harnessed for regenerative medicine.
Since the first isolation of mesenchymal stem cells from lipoaspirate in the early 2000s, adipose tissue has been a darling of regenerative medicine. It is abundant, easy to access, and contains hi...
03/29/2021
Challenges and opportunities in exosome research—Perspectives from biology, engineering, and cancer therapy
This review article takes a critical look at the prospects and challenges in using extracellular vesicles for cancer detection and therapy, through the lenses of both basic science and engineering.
Exosomes are small (∼30–140 nm) lipid bilayer-enclosed particles of endosomal origin. They are a subset of extracellular vesicles (EVs) that are secreted by most cell types. There has been growing ...
03/11/2021
Injectable, macroporous scaffolds for delivery of therapeutic genes to the injured spinal cord
Incorporating regular macropores into injectable hydrogels improves tissue repair and efficacy of locally delivered gene therapies after spinal cord injury in mice.
UCLA
Biomaterials are being developed as therapeutics for spinal cord injury (SCI) that can stabilize and bridge acute lesions and mediate the delivery of transgenes, providing a localized and sustained...
03/11/2021
Injectable Porous Scaffolds Promote Better, Quicker Healing After Spinal Cord Injuries - AIP Publishing LLC
Injectable Porous Scaffolds Promote Better, Quicker Healing After Spinal Cord Injuries - AIP Publishing LLC
Link to article: Injectable, macroporous scaffolds for delivery of therapeutic genes to the injured spinal cord DOI: 10.1063/5.0035291 WASHINGTON, ...
03/08/2021
Bioengineering the neurovascular niche to study the interaction of neural stem cells and endothelial cells
This review article covers the current state of art bioengineered models to mimic the microenvironment of the neurovascular niche and use it to better understand the interactions of neural stem cells and endothelial cells.
Northeastern University
The ability of mammalian neural stem cells (NSCs) to self-renew and differentiate throughout adulthood has made them ideal to study neurogenesis and attractive candidates for neurodegenerative dise...
03/08/2021
Neurovascular niche review introduces bioengineers to neural stem cells
Neurovascular niche review introduces bioengineers to neural stem cells
Biologists’ understanding of the neurovascular niche, an important area in brain science, could benefit from bioengineering contributions.
03/04/2021
Stimuli-responsive biomaterials for cardiac tissue engineering and dynamic mechanobiology
This new article highlights recent development of stimuli-responsive biomaterials to reproduce the complex and dynamic microenvironment of the native heart for cardiac tissue engineering and dynamic mechanobiology studies.
Syracuse University
Since the term “smart materials” was put forward in the 1980s, stimuli-responsive biomaterials have been used as powerful tools in tissue engineering, mechanobiology, and clinical applications. For...
02/18/2021
Recent advances on polymeric hydrogels as wound dressings
The review summarizes the deficiencies and advantages of various existing wound dressings, and outlines the recent advances, challenges and future perspectives of high-performance hydrogel wound dressings.
Severe hemorrhage is a leading cause of high mortality in critical situations like disaster, accidents, and warfare. The resulting wounds could induce severe physical and psychological trauma to pa...
02/18/2021
FRESH 3D-Printing Platform Paves Way for Tissues, Organs - AIP Publishing LLC
FRESH 3D-Printing Platform Paves Way for Tissues, Organs - AIP Publishing LLC
Link to article: Emergence of FRESH 3D printing as a platform for advanced tissue biofabrication DOI: 10.1063/5.0032777 WASHINGTON, February 16, 20...
02/18/2021
Hydrogel Promotes Wound Healing Better Than Traditional Bandages, Gauzes - AIP Publishing LLC
Hydrogel Promotes Wound Healing Better Than Traditional Bandages, Gauzes - AIP Publishing LLC
Link to article: Recent advances on polymeric hydrogels as wound dressings DOI: 10.1063/5.0038364 WASHINGTON, February 16, 2021 — The widespread us...
02/11/2021
Biomaterials Could Mean Better Vaccines, Virus-Fighting Surfaces - AIP Publishing LLC
Biomaterials Could Mean Better Vaccines, Virus-Fighting Surfaces - AIP Publishing LLC
Link to article: Biomaterials-based formulations and surfaces to combat viral infectious diseases DOI: 10.1063/5.0029486 WASHINGTON, February 9, 20...
02/04/2021
Cancer Research Expands Body's Own Immune System to Kill Tumors - AIP Publishing LLC
Cancer Research Expands Body's Own Immune System to Kill Tumors - AIP Publishing LLC
Link to article: Perspective: Modeling the tumor immune microenvironment for drug discovery using 3D culture DOI: 10.1063/5.0030693 WASHINGTON, Feb...
01/28/2021
In-gel fluorescence detection by DNA polymerase elongation
Characterization of an in-gel polymerase elongation process revealed that DNA polymerase diffusion was impeded by molecular interactions with immobilized DNA. This finding will inform design of gel-based assays.
UC Berkeley
Fluorescence-based DNA readouts are increasingly important in biological research, owing to enhanced analytical sensitivity and multiplexing capability. In this study, we characterize an in-gel pol...
01/26/2021
Peptide functionalized liposomes for receptor targeted cancer therapy
Check our latest in APL Bioengineering by on peptide functionalized liposomes for receptor targeted cancer therapy!
University of Pennsylvania
Most clinically approved cancer therapies are potent and toxic small molecules that are limited by severe off-target toxicities and poor tumor-specific localization. Over the past few decades, atte...
01/25/2021
Reconstituting the dynamics of endothelial cells and fibroblasts in wound closure
In response to injury, endothelial cells and fibroblasts within an engineered 3D vascularized tissue dynamically contract the wound, migrate, and distribute matrix to close the void.
Boston University College of Engineering
Boston University
The formation of healthy vascularized granulation tissue is essential for rapid wound closure and the prevention of chronic wounds in humans, yet how endothelial cells and fibroblasts coordinate du...
01/22/2021
Toward improved models of human cancer
This perspective by Alana Welm and colleagues outlines the challenges of modeling the complexities of cancer and new progress toward improved in vivo models to advance therapeutic development.
The University of Utah
Human cancer is a complex and heterogeneous collection of diseases that kills more than 18 million people every year worldwide. Despite advances in detection, diagnosis, and treatments for cancers,...
01/19/2021
Microrheology for biomaterial design
Microrheology is a versatile tool for material characterization. Its use as a tool in designing biomaterials as physiological models, tissue engineering scaffolds, and therapeutic delivery vehicles are described in this new review in APL Bioengineering.
University of Maryland
Microrheology analyzes the microscopic behavior of complex materials by measuring the diffusion and transport of embedded particle probes. This experimental method can provide valuable insight into...
01/15/2021
Emerging applications at the interface of DNA nanotechnology and cellular membranes: Perspectives from biology, engineering, and physics
How can we use DNA nanostructures to probe cellular membranes? Here researchers review DNA nanotechnology, membrane biophysics, delivery strategies and recent advances in applications for DNA nanotechnology at the membrane interface.
Carnegie Mellon University Carnegie Mellon Mechanical Engineering Department
CMU Physics Department
DNA nanotechnology has proven exceptionally apt at probing and manipulating biological environments as it can create nanostructures of almost arbitrary shape that permit countless types of modifica...
01/14/2021
Evaluation of current diagnostic methods for COVID-19
COVID-19 can be diagnosed by several tests like molecular-, immuno-, and nano-based assays. However, it is an urgent requirement to discover more sensitive, specific, fast, and accurate tests.
Yıldız Teknik Üniversitesi
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the agent responsible for the coronavirus disease of 2019 (COVID-19), which triggers lung failure, pneumonia, and multi-organ dysfunc...
01/13/2021
Computational models of migration modes improve our understanding of metastasis
Metastatic cells navigate heterogeneous tumor microenvironments. Insights from computational models of migration modes with implications on metastasis are discussed and open questions are highlighted.
UC San Diego
Tumor cells migrate through changing microenvironments of diseased and healthy tissue, making their migration particularly challenging to describe. To better understand this process, computational ...
Address
Melville, NY
11747
Telephone
Website
Alerts
Be the first to know and let us send you an email when APL Bioengineering posts news and promotions. Your email address will not be used for any other purpose, and you can unsubscribe at any time.
Category
Nearby media companies
-
1305 Walt Whitman Rd
-
1305 Walt Whitman Rd
-
1305 Walt Whitman Rd
-
200 Broadhollow Rd, Suite 207
-
150 broadhallow rd
-
95 Broadhollow Road
-
316 S Service Rd
-
Equal Opportunity Publications (EOP)
425 Broad Hollow Rd, Ste. 418 -
371 S. Oyster Bay Rd, Plainview
-
48 South Service Road, Suite 203, Plainview
-
95 Broadhollow Road
-
4 Newtown PLZ, New York
-
871 Walt Whitman Rd
-
696 Old Bethpage Rd, Ste 38, Old Bethpage
-
80 Skyline Drive, Plainview
Other Publishers in Melville
-
1305 Walt Whitman Rd -
11747
-
1305 Walt Whitman Rd
-
600A Walt Whitman Rd
-
Equal Opportunity Publications (EOP)
425 Broad Hollow Rd, Ste. 418
Comments
Collaborative research from UW-Madison Department of Biomedical Engineering Professor Pamela Kreeger and UW-Madison Department of Engineering Physics Assistant Professor Jacob Notbohm shows the effect of healthy cell arrangement on ovarian cancer metastasis.
The researchers published their findings recently in the journal APL Bioengineering, by AIP Publishing.
https://direc.to/hcaj
The researchers published their findings recently in the journal APL Bioengineering, by AIP Publishing.
https://direc.to/hcaj
Catch up on some of the most downloaded research published in APL Bioengineering.
Check out what your peers are reading with some of the most downloaded research in APL Bioengineering.
Check out one of the most downloaded APL Bioengineering articles.
Highlighted research in systems biology and computational biology/bioengineering from APL Bioengineering.
Highlighted research in systems biology and computational biology/bioengineering from APL Bioengineering.
Highlighted research in systems biology and computational biology/bioengineering from APL Bioengineering!
Read the latest research in systems biology and computational biology/bioengineering from APL Bioengineering!
Highlighted research in Engineered Living Systems from APL Bioengineering.
Read one of the most cited articles published in APL Bioengineering.
A top cited article from APL Bioengineering!
Read from APL Bioengineering's Special Topic: Biohybrid Machines.