06/16/2026
On the evening of October 12, 2018, 16-year-old Karlie Gusé told her dad and stepmother she was heading to a high school football game in Chalfant Valley, California.
She didn't go to the game.
Instead, she went to a house party with her boyfriend. She smoked ma*****na that night — something she had done before, but this time, it didn't go well. She got scared of the music. She got scared of her boyfriend. She called her stepmother Melissa in a panic and begged her to come pick her up.
When Melissa arrived, Karlie was running down the street, pale as a ghost, with her pupils fully dilated. Melissa got her home and spent the night in her room trying to calm her down. Sometime after 5 a.m., Melissa fell asleep.
When she woke up around 7 a.m., Karlie was gone. She had left with no phone, no wallet, and no coat — in the freezing high desert cold.
Three witnesses spotted her that morning walking toward U.S. Highway 6, a desolate stretch of road heading north to the Nevada border. Search dogs tracked her scent all the way to the highway's edge.
Then the trail went cold.
The FBI got involved. The internet fractured into competing theories, but none of them led anywhere.
Then, in 2021, a tip came in: a witness claimed to have seen a girl matching Karlie's description at a party in Tonopah, Nevada — a small mining town more than 100 miles up Highway 6, across the state line. Investigators say they identified a vehicle that may have carried her there.
Karlie has never been found. She would be 24 years old today.
We covered her full story on the latest episode of And Then They Were Gone. Link in comments.
If you have information about Karlie's whereabouts, please contact the Mono County Sheriff's Office at [email protected].