Genetic Engineering & Biotechnology News

06/08/2025

Multi-Sensor Monitoring of Cell Number and Viability

Multivariate-regression models can predict the number of cells and the percentage of viable cells in multi-well plates.

Universiteit Hasselt

Multivariate-regression models can predict the number of cells and the percentage of viable cells in multi-well plates.

06/07/2025

Industrial-Scale Protein-Folding in One-Step Modulation

The continuous, solid-phase system achieved a refolding yield of approximately 100% by gradually pumping lysozyme through the column.

Nankai University, South China University of Technology

The continuous, solid-phase system achieved a refolding yield of approximately 100% by gradually pumping lysozyme through the column.

06/07/2025

🎧 GEN's New Episode of Touching Base Is Available!

In this episode, we cover clinical trial updates, Boltz-2’s AI drug discovery debut, plasma exchange’s anti-aging potential, and a universal CAR T therapy that could transform immunotherapy. GEN’s Alex Philippidis, Fay Lin, PhD, Uduak Thomas, and Corinna Singleman, PhD, highlight standout GEN coverage.

This week's episode covers a wide range of topics from open-source AI to clinical trials to increasing longevity.

06/07/2025

A Simpler Process for mRNA Purification

Downstream processing for mRNA manufacturing is currently too complex, but simplifying by using precipitation looks promising.

Massachusetts Institute of Technology (MIT)

Downstream processing for mRNA manufacturing is currently too complex, but simplifying by using precipitation looks promising.

06/07/2025

HSV-1 Encephalitis Prevented by Treatment Targeting Viral Enzymes

A key viral mechanism that allows HSV-1 to evade the brain’s natural defenses has been uncovered and tested to identify new treatments. Research has suggested that HSV-1 has a relationship to other neurological conditions like Alzheimer’s disease.

University Of Tokyo

A key viral mechanism that allows HSV-1 to evade the brain’s natural defenses has been uncovered and tested to identify new treatments.

06/07/2025

Disrupting Mechanical Transmission by Titin Protein Precipitates Muscle Diseases

Centro Nacional de Investigaciones Cardiovasculares (CNIC) findings suggest that slack titin molecules drive muscle disease, potentially through mechanisms shared with other mechanical proteins.

Findings suggest that slack titin molecules drive muscle disease, potentially through mechanisms shared with other mechanical proteins.

06/06/2025

AAV Gene Therapy Eases Alzheimer’s Symptoms in Mice

Mice treated with the therapy had better cognitive function and similar patterns of gene expression to healthy models of the same age.

UC San Diego

Mice treated with the therapy had better cognitive function and similar patterns of gene expression to healthy models of the same age.

06/06/2025

Multiple Sclerosis Society Announces MS Research and Funding Opportunities

Researchers still don’t fully understand the cause of multiple sclerosis or why the rate of progression is so difficult to determine.

National Multiple Sclerosis Society !America

Researchers still don’t fully understand the cause of multiple sclerosis or why the rate of progression is so difficult to determine.

06/06/2025

Epitranscriptomics: A New Frontier in RNA Epigenetics 25 Years After the Human Genome Project

Interest in epitranscriptomics has surged due to its role in cellular development and disease, as well as its potential in diagnostics, therapeutics, and biotechnology

Chemical RNA modifications reveal regulatory mechanisms beyond genetic sequence.

06/06/2025

Boltz-2 Released to Democratize AI Molecular Modeling for Drug Discovery

The Massachusetts Institute of Technology (MIT) model predicts molecular binding affinity at newfound speed and accuracy, offering a powerful tool for commercial drug discovery.

The MIT model predicts molecular binding affinity at newfound speed and accuracy, offering a powerful tool for commercial drug discovery.

06/06/2025

Cell and Gene Therapy Leaders Tell FDA: “Believe in American Solutions”

Leaders from the world of cell and gene therapy shared their personal stories and policy recommendations in an extraordinary roundtable conducted by the FDA in front of its recently-appointed top officials. The roundtable was conducted in front of the U.S. Food and Drug Administration's recently appointed top officials—director Martin A. Makary, MD, and Vinayak (Vinay) Kashyap Prasad, MD. They were joined for the closing session by three other top healthcare leaders of President Donald Trump’s administration: Robert F. Kennedy, Jr., Secretary of the U.S. Department of Health and Human Services (HHS); the new National Institutes of Health (NIH) director Jayanta (Jay) Bhattacharya, MD, PhD; and Mehmet Oz, MD.

Leaders from the world of cell and gene therapy shared their personal stories and policy recommendations in an extraordinary roundtable conducted by the FDA in front of its recently-appointed top officials.

06/06/2025

NEW PODCAST! From Functional Genomics to Cell Therapy: The Role of CRISPR-Based Gene Editing

In this episode, experts will discuss applications of gene editing to improve scientists’ understanding of the relationship between variant and disease in functional genomics studies. They will also talk about the Dharmacon product suite which is designed for CRISPR-based targeted editing in a wide range of cells. LISTEN to this free podcast sponsored by Revvity: https://hubs.li/Q03qW2KW0