Journal of Cell Biology

Journal of Cell Biology The Journal of Cell Biology publishes peer-reviewed research on all aspects of cellular structure and function. Published by Rockefeller University Press.

Spotlight: Jeff Hardin (UW Integrative Biology) highlights recent work from Teng et al. of the Bush lab (https://hubs.la...
12/19/2025

Spotlight: Jeff Hardin (UW Integrative Biology) highlights recent work from Teng et al. of the Bush lab (https://hubs.la/Q03YKjmx0), studying the function of p120-catenin and -mediated in upper lip fusion in mammalian embryos. https://hubs.la/Q03YKkfw0

Zhengyang Guo, Guangshuo Ou et al. (Tsinghua University) introduce SynSeg, a method that eliminates manual annotation by...
12/18/2025

Zhengyang Guo, Guangshuo Ou et al. (Tsinghua University) introduce SynSeg, a method that eliminates manual annotation by training models on synthetic data from abstracted “primitives” to robustly segment diverse subcellular structures https://hubs.la/Q03YD36P0

Spotlight: Ivan Radin discusses new work from Ryken et al. (https://hubs.la/Q03YtRht0) which shows how localization and ...
12/17/2025

Spotlight: Ivan Radin discusses new work from Ryken et al. (https://hubs.la/Q03YtRht0) which shows how localization and function of autoinhibitory calcium ATPases maintains the strength of the tip-focus Ca2²⁺ gradient during polarized plant growth. https://hubs.la/Q03YtQd40

Congratulations 🏆 Yu Deng from the Peter Devreotes's lab at Johns Hopkins University, winner of the JCB 2025 Norton B. G...
12/16/2025

Congratulations 🏆 Yu Deng from the Peter Devreotes's lab at Johns Hopkins University, winner of the JCB 2025 Norton B. Gilula Travel Award!

📸 Yu with Rockefeller University Press's Ben Short at Cell Bio 2025, the annual meeting of The American Society for Cell Biology

Congratulations 🏆 Justus Francis of the Saikat Chowdhury's lab at CSIR-Centre for Cellular and Molecular Biology, the wi...
12/16/2025

Congratulations 🏆 Justus Francis of the Saikat Chowdhury's lab at CSIR-Centre for Cellular and Molecular Biology, the winner of the JCB's 2025 Alan Hall Travel Award!

📸 Justus with JCB Executive Editor Tim Spencer at , annual meeting of The American Society for Cell Biology

Aya Ben-Hamo-Arad, Hila Toledano and colleagues (אוניברסיטת חיפה - University of Haifa) reveal that cyst cells exist i...
12/16/2025

Aya Ben-Hamo-Arad, Hila Toledano and colleagues (אוניברסיטת חיפה - University of Haifa) reveal that cyst cells exist in two functionally distinct subpopulations: transient es**rt cells derived from divisions & long-lived steady cyst cells that persist at the te**is apex & mediate phagoptosis https://hubs.la/Q03Ym3mp0

Thomas Jacqmin, Marielle Boonen and colleagues (Université de Namur) report that the loss of maspardin, which is deficie...
12/16/2025

Thomas Jacqmin, Marielle Boonen and colleagues (Université de Namur) report that the loss of maspardin, which is deficient in spastic paraplegia 21, results in RAB7 hyperactivation due to mislocalization. This abnormal RAB7 localization leads to defects in & disruption of the mTOR–TFEB pathway. https://hubs.la/Q03Ym3sx0

Help choose JCB’s cover of the year! Explore 12 breathtaking images submitted by our talented authors and vote for your ...
12/15/2025

Help choose JCB’s cover of the year! Explore 12 breathtaking images submitted by our talented authors and vote for your favorite. Voting closes on Wed. December 31. Don’t miss your chance to have your say in celebrating the beauty of science 👉 https://hubs.la/Q03WgJWL0

Rashmi Budhathoki, J. Todd Blankenship et al. show that nuclear dispersion relies on a transition from centrosomal to nu...
12/11/2025

Rashmi Budhathoki, J. Todd Blankenship et al. show that nuclear dispersion relies on a transition from centrosomal to nucleus-associated, non-centrosomal microtubules during Drosophila tissue extension. Disrupting TIP protein function impairs ncMT stability and nuclear dispersion and reveals a fundamental antagonism between centrosomal and ncMT networks essential for epithelial remodeling. https://hubs.ly/Q03XSnG30

Michal Shahar, Anat Florentin et al. reveal how the malaria parasite’s apicoplast develops through four distinct stages ...
12/10/2025

Michal Shahar, Anat Florentin et al. reveal how the malaria parasite’s apicoplast develops through four distinct stages linked to nuclear replication. They identify a unique “Crown” stage critical for organelle inheritance, establishing key connections between parasite cell cycle control, organelle genome, and apicoplast segregation. https://hubs.ly/Q03XDn6V0

Ana Rosa Sáez-Ibáñez, Ingvar Ferby et al. (Uppsala University) show that ErbB3 regulates Integrin β1 recycling in breast...
12/05/2025

Ana Rosa Sáez-Ibáñez, Ingvar Ferby et al. (Uppsala University) show that ErbB3 regulates Integrin β1 recycling in breast epithelial cells independently of ligand signaling. Its loss redirects cargo to extracellular vesicles, impairs migration & reveals a novel role for pseudo-RTKs in vesicular trafficking https://hubs.la/Q03X3Mbx0

Kun Gao, Changying Guo (Xinjiang University), Liang Jin (China Pharmaceutical University) and colleagues show that a spe...
12/03/2025

Kun Gao, Changying Guo (Xinjiang University), Liang Jin (China Pharmaceutical University) and colleagues show that a specific long noncoding RNA EGFR-AS1 directly facilitates the repair of broken DNA. Targeting this RNA effectively sensitizes lung cells to , offering a promising strategy to overcome treatment resistance. https://hubs.la/Q03WGvxf0

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