Journal of Cell Biology

Journal of Cell Biology The Journal of Cell Biology publishes peer-reviewed research on all aspects of cellular structure and function. Published by Rockefeller University Press.

In this Tools article, Cao, Peng, and Yang et al. from Huazhong Agricultural University present a high-content image-bas...
11/17/2025

In this Tools article, Cao, Peng, and Yang et al. from Huazhong Agricultural University present a high-content image-based phenotyping pipeline for quantitative analysis of organelle morphology. The interpretable feature-based method detects both prominent and subtle phenotypic changes and uncovers Golgi-cilia dynamics associated with the G0/G1 transition and AURKA activity. Read “High-content phenotyping reveals Golgi dynamics and their role in cell cycle regulation” 👉 https://hubs.la/Q03Tmbgb0

Attending in San Diego? JCB's Executive Editor Tim Spencer will be available for a chat TODAY (Monday) 1:30pm - 2:30pm...
11/17/2025

Attending in San Diego? JCB's Executive Editor Tim Spencer will be available for a chat TODAY (Monday) 1:30pm - 2:30pm ! Stop by Rockefeller University Press booth #3719 to discuss your research with Tim and learn about JCB's publication process! 🧠 📝

Attending in San Diego? Visit Rockefeller University Press booth #3719 to chat about the journal and pick up our Co...
11/17/2025

Attending in San Diego? Visit Rockefeller University Press booth #3719 to chat about the journal and pick up our Collection magazine 📚 as well as an exclusive pouch! 🎁 We look forward to meeting you! 💬 💡

11/14/2025

New from the Masanori Mishima & Mohan Balasubramanian labs at Warwick Medical School: “Actin arginylation alters myosin engagement & F-actin patterning despite structural conservation,” published in Journal of Cell Biology. Actin is vital for cell functions and is regulated by posttranslational modifications like arginylation. The structure of arginylated β-actin (R-β-actin) is nearly identical to non-modified actin. However, arginylation alters myosin-II interactions and impacts actin filament organization and cytokinesis in cells. Explore the of with Mishima, Balasubramanian and colleagues 👉 https://hubs.la/Q03Tm07G0

Camilla Teng et al. of the Jeffrey Bush lab (UCSF) reveal cellular mechanisms of tissue fusion in the developing face. T...
11/13/2025

Camilla Teng et al. of the Jeffrey Bush lab (UCSF) reveal cellular mechanisms of tissue fusion in the developing face. They demonstrate that actomyosin-generated forces drive tissue fusion, necessitating an elevated cadherin threshold. https://hubs.la/Q03T2rzZ0

Spotlight: Juan Martin-Serrano (King's College London) highlights work from Dam, Moreno, Brownlow, Mendoza et al. (https...
11/12/2025

Spotlight: Juan Martin-Serrano (King's College London) highlights work from Dam, Moreno, Brownlow, Mendoza et al. (https://hubs.la/Q03SP2Gd0), which reveals how Srs2/PARI act as a missegregated chromatin sensor for NoCut, delaying cytokinetic abscission. https://hubs.la/Q03SP0NM0

Explore new discoveries in cellular neurobiology to accompany Society for Neuroscience's ! Our new collection comprises...
11/12/2025

Explore new discoveries in cellular neurobiology to accompany Society for Neuroscience's ! Our new collection comprises novel findings regarding tau- and α-synuclein aggregation and explores mechanisms underlying dendrite branching, axonal regeneration, and survival: https://hubs.la/Q03SwtQR0

Viewpoint: Fred Mast, Richard Rachubinski, and John Aitchison (Seattle Children's) challenge the PPAR paradigm and show ...
11/11/2025

Viewpoint: Fred Mast, Richard Rachubinski, and John Aitchison (Seattle Children's) challenge the PPAR paradigm and show human expand via hominid-specific pathways that link specialization to immunometabolic functions. https://hubs.la/Q03SCS8g0

Yanyan Li, Hongchang Li al. reveal that Aurora A–mediated phosphorylation of Numb triggers its dissociation from the pla...
11/10/2025

Yanyan Li, Hongchang Li al. reveal that Aurora A–mediated phosphorylation of Numb triggers its dissociation from the plasma membrane, thereby promoting I–dependent membrane-to-cortex adhesion required for mitotic cell rounding https://hubs.la/Q03SqzQf0

Belén Calvo, Sandip Patel, Teresa Alonso, and colleagues (Universidad de Valladolid) describe a new bioluminescent senso...
11/07/2025

Belén Calvo, Sandip Patel, Teresa Alonso, and colleagues (Universidad de Valladolid) describe a new bioluminescent sensor for measuring luminal Ca²⁺ in a mildly acidic subcompartment of the endo-lysosomal system. https://hubs.la/Q03ScdR50

Hiroki Okada, Erfei Bi and colleagues (Perelman School of Medicine at the University of Pennsylvania) show that Bni5 int...
11/06/2025

Hiroki Okada, Erfei Bi and colleagues (Perelman School of Medicine at the University of Pennsylvania) show that Bni5 interacts with filaments, septin-associated kinase, and -II to regulate septin hourglass architecture and remodeling, retrograde flow, and https://hubs.la/Q03S2bJk0

11/06/2025

Peiyao Fan, Yang Chen et al. (Peking University) show that tubular ER extends into retraction fibers and through -dependent ER extension and ER-plasma membrane contact sites in migrating cells. https://hubs.la/Q03S214l0

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