Journal of Cell Biology

Journal of Cell Biology The Journal of Cell Biology publishes peer-reviewed research on all aspects of cellular structure and function. Published by Rockefeller University Press.

Ana Rosa Sáez-Ibáñez, Ingvar Ferby et al. (Uppsala University) show that ErbB3 regulates Integrin β1 recycling in breast...
12/05/2025

Ana Rosa Sáez-Ibáñez, Ingvar Ferby et al. (Uppsala University) show that ErbB3 regulates Integrin β1 recycling in breast epithelial cells independently of ligand signaling. Its loss redirects cargo to extracellular vesicles, impairs migration & reveals a novel role for pseudo-RTKs in vesicular trafficking https://hubs.la/Q03X3Mbx0

Kun Gao, Changying Guo (Xinjiang University), Liang Jin (China Pharmaceutical University) and colleagues show that a spe...
12/03/2025

Kun Gao, Changying Guo (Xinjiang University), Liang Jin (China Pharmaceutical University) and colleagues show that a specific long noncoding RNA EGFR-AS1 directly facilitates the repair of broken DNA. Targeting this RNA effectively sensitizes lung cells to , offering a promising strategy to overcome treatment resistance. https://hubs.la/Q03WGvxf0

New work by Valentine Thomas, Sophie Martin and colleagues (Université de Genève) provides a live, 8-nm precision map of...
12/03/2025

New work by Valentine Thomas, Sophie Martin and colleagues (Université de Genève) provides a live, 8-nm precision map of the actin fusion focus for cell-cell fusion in S. . This reveals aster formation by Myo52-driven transport of the formin Fus1 nucleator https://hubs.la/Q03WGjQF0

🌟 Exciting news for JCB readers and Cell Bio 2025 attendees! 🌟 You are invited to choose JCB’s cover of the year: dive i...
12/03/2025

🌟 Exciting news for JCB readers and Cell Bio 2025 attendees! 🌟 You are invited to choose JCB’s cover of the year: dive into a collection of 12 breathtaking scientific images submitted by our talented authors in 2025. Each cover tells a unique story of discovery and innovation.
👉 Click the link to explore these stunning visuals and cast your vote for your favorite.
🗓️ Voting closes on Wednesday, December 31, 2025. Don’t miss your chance to have your say in celebrating the beauty of science!
👉 https://hubs.la/Q03WgHcT0

Attending this weekend and interested in discussing your research with JCB editors? Our editorial team will be availab...
12/03/2025

Attending this weekend and interested in discussing your research with JCB editors? Our editorial team will be available:
🗓️ Sunday, Dec. 7, 1:00 pm–4:00 pm
🗓️ Monday, Dec. 8, 12:00 pm–4:00 pm
🗓️ Tuesday, Dec. 9, 12:00 pm–3:00 pm
📍 Booth #1224

See the Year in Cell Biology, our annual collection highlighting the year's most impactful papers that have garnered exceptional interest from our readership. 👉 https://hubs.la/Q03WfZ3b0

Attending this weekend? Be sure to visit us at Journal of Cell Biology Booth #1224 to chat about the journal, pick up...
12/03/2025

Attending this weekend? Be sure to visit us at Journal of Cell Biology Booth #1224 to chat about the journal, pick up a copy of The Year in Cell Biology: 2025 magazine 📕, and grab one of our exclusive puzzles 🧩

See our annual collection: https://hubs.la/Q03Wg25D0

Our annual collection highlights 13 of the year's most impactful papers that have garnered exceptional interest from our...
12/03/2025

Our annual collection highlights 13 of the year's most impactful papers that have garnered exceptional interest from our readership. Explore cutting-edge findings spanning the diverse spectrum of cell biology 👉 https://hubs.la/Q03V-zkp0


Tessa Arends, Sean Bennett, and Stephen Tapscott (Fred Hutch) show that DUX4-induction of stable intranuclear RNA, inclu...
12/02/2025

Tessa Arends, Sean Bennett, and Stephen Tapscott (Fred Hutch) show that DUX4-induction of stable intranuclear RNA, including pericentromeric HSATII repeat RNA, leads to nuclear protein aggregation. HSATII RNP complexes impact RNA processing downstream of DUX4 expression https://hubs.la/Q03WvkVn0

Evgenia Leikina, Michael M. Kozlov, Leonid V. Chernomordik and colleagues (National Institutes of Health) propose a nove...
12/02/2025

Evgenia Leikina, Michael M. Kozlov, Leonid V. Chernomordik and colleagues (National Institutes of Health) propose a novel signaling pathway linking together intracellular Ca²⁺ signaling, exposure, A5 binding and cortex detachment that facilitates fusion. https://hubs.la/Q03WvgGs0

12/02/2025

Martina Lerche, Mathilde Mathieu, Johanna Ivaska et al. (Turun yliopisto - University of Turku) reveal that newly synthesized can bypass the Golgi to be actively delivered to specific plasma membrane regions, where they enhance cell protrusion and . https://hubs.la/Q03Wvfb10

Tokiwa Yamasaki, Kohtarou Konno (Hokkaido University), Susumu Tomita (Yale School of Medicine) and colleagues show that ...
12/02/2025

Tokiwa Yamasaki, Kohtarou Konno (Hokkaido University), Susumu Tomita (Yale School of Medicine) and colleagues show that GARLH proteins assemble with neuroligins to dictate synapse-type preference. Contrary to prevailing views, endogenous NL1 localizes to both excitatory and inhibitory synapses; when NL2/4 are absent or NL1-GARLH4 binding is enforced, NL1/3 assemble with GARLH4–GABAA receptor complexes, linking neuroligins to inhibitory targeting. https://hubs.la/Q03WsD_k0

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