Journal of Cell Biology

Journal of Cell Biology The Journal of Cell Biology publishes peer-reviewed research on all aspects of cellular structure and function. Published by Rockefeller University Press.

Ahmed Abouelghar, Joseph Carrier, Matthew Miller and colleagues (The University of Utah) show that budding yeast Stu2’s ...
09/03/2025

Ahmed Abouelghar, Joseph Carrier, Matthew Miller and colleagues (The University of Utah) show that budding yeast Stu2’s function is essential for cell viability. Surprisingly, this function is independent of its canonical ability to induce assembly and disassembly. https://hubs.la/Q03GK7jd0

Maria Pia Rodriguez, Cagla Eroglu et al. (Duke Health) show that Drp1-mediated mitochondrial fission is necessary for pe...
09/03/2025

Maria Pia Rodriguez, Cagla Eroglu et al. (Duke Health) show that Drp1-mediated mitochondrial fission is necessary for peripheral process formation. Loss of Drp1 induces astrocyte reactivity & disrupts cortical astrocyte organization https://hubs.la/Q03GK6Kx0

Rongwei Zhao, Huaiying Zhang et al. (Carnegie Mellon University) show that, in cells using the alternative lengthening...
09/03/2025

Rongwei Zhao, Huaiying Zhang et al. (Carnegie Mellon University) show that, in cells using the alternative lengthening of telomeres (ALT) pathway, levels at influence the formation of ALT-associated PML bodies. https://hubs.la/Q03GK1rd0

Anbang Dai, Pietro De Camilli et al. (Yale School of Medicine) report the localization of BLTP2 in different human cell ...
09/03/2025

Anbang Dai, Pietro De Camilli et al. (Yale School of Medicine) report the localization of BLTP2 in different human cell types & reveal binding partners that mediate its tethering to the PM & to PM-connected structures including certain & undergoing fusion https://hubs.la/Q03GJ-Pw0

Our new collection offers cell biologists practical, expert-driven guidance and best practices in the design, ex*****on,...
09/03/2025

Our new collection offers cell biologists practical, expert-driven guidance and best practices in the design, ex*****on, and analysis of experiments, and the subsequent communication of their results to their peers. 👉 https://hubs.la/Q03Fm0dD0

09/02/2025

Alison Wirshing, Daniel Lew et al. (Massachusetts Institute of Technology (MIT)) address how mothers partition growth equally among their buds in the multi-budding yeast Aureobasidium pullulans. Equal partitioning stems directly from effective equalization of sites. https://hubs.la/Q03GsTgp0

Our September issue is here! https://hubs.la/Q03FQSsG0The cover shows Airyscan super-resolution immunofluorescence image...
09/01/2025

Our September issue is here! https://hubs.la/Q03FQSsG0
The cover shows Airyscan super-resolution immunofluorescence image of HeLa cells stained for two types of intermediate filaments: vimentin (magenta) and keratin-8 (cyan). Both filament networks form dense bundles around the cell nucleus. Vimentin filaments are concentrated in the central part of the cell and do not extend to the cell margin. In contrast, keratin-8 spans the entire cell, connecting to the plasma membrane via desmosomes that link keratin networks of adjacent cells.
From Pasolli et al. https://hubs.la/Q03FQTkR0

08/29/2025

Shiori Akayama, Takayuki Shima, Shuhei Nakamura et al. (Nara Medical University) show that TFEB is regulated by at least two different regulatory mechanisms during lysosomal damage: ATG conjugation system–dependent/independent regulation. https://hubs.la/Q03Gcc6J0

08/29/2025

The multinucleate, multibudding yeast, A. pullulans delivers nuclei into each daughter bud during . Claudia Petrucco, Amy S. Gladfelter (Duke University School of Medicine), Daniel Lew (Massachusetts Institute of Technology (MIT)) and colleagues image during mitosis, revealing mechanisms ensuring that most daughters inherit one & only one nucleus https://hubs.la/Q03GccZL0

Kylie Deng, Peter Thorn et al. (University of Sydney) report that liprin-α1 is part of a glucose-regulated complex contr...
08/28/2025

Kylie Deng, Peter Thorn et al. (University of Sydney) report that liprin-α1 is part of a glucose-regulated complex controlling the positioning of granule fusion, revealing a novel step in the mechanism of stimulus–secretion coupling. https://hubs.la/Q03G1kHF0

Truc Losier, Ryan Russell et al. (uOttawa)identify distinct kinase signaling pathways that differentially regulate bulk ...
08/21/2025

Truc Losier, Ryan Russell et al. (uOttawa)identify distinct kinase signaling pathways that differentially regulate bulk and selective . Using kinome-wide screening, they reveal both shared and pathway-specific regulators https://hubs.la/Q03DSvdK0

Spotlight: Woo Young Chung and Shmuel Muallem (National Institute of Dental Craniofacial Research) discuss recent work f...
08/19/2025

Spotlight: Woo Young Chung and Shmuel Muallem (National Institute of Dental Craniofacial Research) discuss recent work from Militsin et al. (https://hubs.la/Q03DnbN40) revealing how STIM1 and STIM2 affect cell migration by regulating IP₃R-mediated Ca²⁺ release. https://hubs.la/Q03DncDK0

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