Review of Ophthalmology

Review of Ophthalmology News, information & other items of interest from the editors of Review of Ophthalmology.

Review of Ophthalmology highlights current, clinically relevant information on surgical techniques, disease diagnosis and management and new technologies. Its physician and staff editors present timely reports in a format that stresses accessible editorial information and graphics, including news, regulatory issues, ophthalmic sub-specialties such as glaucoma, retina, refractive surgery, cornea an

d external disease, pediatric ophthalmology and oculoplastics, as well as coverage of practice management, contact lenses and optical.

Real-world DME outcomes lag behind clinical trials—patients often receive fewer injections (≈4–7 in year 1) and gain few...
01/05/2026

Real-world DME outcomes lag behind clinical trials—patients often receive fewer injections (≈4–7 in year 1) and gain fewer letters (+4–5 vs +9–13 in trials).

This column digs into IRIS and Vestrum data to explain why (visit burden, loss to follow-up, step therapy, protocol differences, underuse of laser, and disparities by race/insurance) and what clinicians can do about it.

Read here: https://www.reviewofophthalmology.com/article/undertreatment-of-diabetic-macular-edema

Click here to read all the articles in our series:
https://www.reviewofophthalmology.com/issue/2025-year-in-review

Secondary IOL Implantation in ChildrenA recent study offers updated guidance regarding complications and refractive outc...
01/05/2026

Secondary IOL Implantation in Children

A recent study offers updated guidance regarding complications and refractive outcomes.

A total of 80 children (108 eyes) with nontraumatic cataracts who subsequently underwent secondary IOL implantation were included in this study. Thirty-two children had bilateral secondary IOLs (60 eyes) and 48 had unilateral secondary IOLs. The median age at lensectomy was 1.6 months for bilateral cases and 2.7 months for unilateral cases. At secondary IOL implantation, the median age was 2.7 years for bilateral cases and 2.1 years for unilateral cases. Median follow-up after secondary IOL implantation was 2.7 years for bilateral and 2.1 years for unilateral cases.

The three-year cumulative incidence of a glaucoma-related adverse event (glaucoma or glaucoma suspect) was 17% in bilateral cases and 12% in unilateral cases. The cumulative incidence of surgery for visual axis opacification was 2% for bilateral and 4% for unilateral.

Read more: https://www.reviewofophthalmology.com/article/secondary-iol-implantation-in-children

In this Technology Update, hear from surgeons, practice leaders, and industry innovators on building a cross‑functional ...
01/04/2026

In this Technology Update, hear from surgeons, practice leaders, and industry innovators on building a cross‑functional digital team; segmenting audiences (LASIK/ICL vs cataract/RLE); SEO and Google Business Profile optimization; conversion‑focused websites; paid and social ads with surgeon‑forward creatives; leveraging reviews/testimonials and influencer partnerships; exploring streaming/CTV campaigns; and staying transparent and FTC‑compliant on reviews.

Read here: https://www.reviewofophthalmology.com/article/growing-your-business-digitally

Click here to read all the articles in our series:
https://www.reviewofophthalmology.com/issue/2025-year-in-review

Several new treatments for patients with limbal stem cell deficiency have emerged in the last two decades. These cell-ba...
01/02/2026

Several new treatments for patients with limbal stem cell deficiency have emerged in the last two decades. These cell-based therapies use smaller amounts of donor tissue compared to standard approaches like conjunctival limbal autografts and many also involve expanding cultured cells in the lab.

Here, Ula Jurkunas, MD, discusses these approaches and shares the latest results of a new stem cell therapy for cornea: https://www.reviewofophthalmology.com/article/cell-therapy-for-lscd

Click here to read all the articles in our series:
https://www.reviewofophthalmology.com/issue/2025-year-in-review

Exploring Technology For TeleophthalmologyHere are some software applications that could be useful to practices with tel...
01/02/2026

Exploring Technology For Teleophthalmology

Here are some software applications that could be useful to practices with telehealth services:

💻 Doximity App — A HIPAA-compliant professional network and communication app where ophthalmologists can call, message, refer patients, and send documents. Includes DoxGPT, an AI tool that answers eye-care questions and helps research drugs using peer‑reviewed sources.

💻 Doxy.me — A HIPAA-compliant, browser- and mobile-based telemedicine platform for secure video visits. Lets clinicians manage virtual waiting rooms, organize consultations, run pre-call tests, and review meeting histories.

💻 Amwell — A HIPAA-compliant virtual care platform that connects to your EHR so clinicians can conduct video visits while viewing records side-by-side. Notes taken during the visit can be integrated back into the EHR.

💻 AdvancedMD — An EHR and telemedicine platform (desktop and mobile) with a scheduler and dashboard to organize and run telehealth appointments.

💻 Alleye — A patient-facing mobile app for self-screening retinal conditions. Provides home eye tests, a treatment log to track retinal injections, and calendar reminders for appointments and screening intervals.

💻 Eye Patient — Website and mobile app offering an eye doctor directory, patient education, news, and a product store. The app adds appointment reminders, prescription overviews, self-screening tests, an IOL selector, and a dry-eye calculator to support telemedicine workflows.

Read more in the latest Technology Update: https://www.reviewofophthalmology.com/article/exploring-technology-for-teleophthalmology

Since it was first introduced in 2017, the Yamane technique for intrascleral IOL fixation has been widely adopted. Propo...
01/01/2026

Since it was first introduced in 2017, the Yamane technique for intrascleral IOL fixation has been widely adopted. Proponents of this method often cite its minimally invasive approach and ability to provide improved stability in challenging cases, but it’s no secret that the learning curve is steep.

Read more: https://www.reviewofophthalmology.com/article/refining-the-yamane-technique

Click here to read all the articles in our series:
https://www.reviewofophthalmology.com/issue/2025-year-in-review

In this installment of The Forum, Mark Blecher, MD, discusses his lifelong struggle with anger and impulse control, how ...
12/31/2025

In this installment of The Forum, Mark Blecher, MD, discusses his lifelong struggle with anger and impulse control, how he forged a calmer “Mark 2.0” persona, and how escalating stress in his role as CMO has reawakened old tendencies. He resolves to pause, step back and keep working to maintain composure until he retires again.

Read here: https://www.reviewofophthalmology.com/article/mark-20

Click here to read all the articles in our series:
https://www.reviewofophthalmology.com/issue/2025-year-in-review

A Review of Retinopathy Of PrematurityToday's management hinges on precise staging, improved diagnostic tools and person...
12/31/2025

A Review of Retinopathy Of Prematurity

Today's management hinges on precise staging, improved diagnostic tools and personalized treatment algorithms.

Aggressive ROP is used to characterize rapidly progressing disease with severe neovascularization, plus disease, AV shunting or flat neovascularization (see image). Previously called aggressive posterior ROP and usually diagnosed in extremely preterm infants, it’s now recognized that AROP isn’t limited to the posterior retina and may occur in larger preterm infants.

AROP requires vigilant screening and timely intervention— otherwise the disease can bypass the typical progressive stages of ROP and quickly advance to more severe stages including retinal detachment.

Keep reading: https://www.reviewofophthalmology.com/article/a-review-of-retinopathy-of-prematurity

In this installment of Editor's Page, the editor-in-chief of this magazine, Walter Bethke, discusses why Wills Eye Hospi...
12/30/2025

In this installment of Editor's Page, the editor-in-chief of this magazine, Walter Bethke, discusses why Wills Eye Hospital is a reimbursement “zebra”—operating like an academic hospital yet paid like an ASC—and proposes fixes such as site‑neutral payments, complexity- and outcome‑based scaling, and center‑of‑excellence contracts.

Read here: https://www.reviewofophthalmology.com/article/its-time-to-think-of-the-zebra

Click here to read all the articles in our series:
https://www.reviewofophthalmology.com/issue/2025-year-in-review

Through mid-January, we’ll be highlighting some top features and columns from 2025. Here's another one.The shortage of o...
12/29/2025

Through mid-January, we’ll be highlighting some top features and columns from 2025. Here's another one.

The shortage of ophthalmologists shouldn’t come as a surprise to anyone, but the severity of the problem differs for a few reasons, including location, according to Jill Maher, MA, COE, the owner of Maher Medical Practice Consulting in Chicago.

“I’ve been recruiting for 10 years now for my clients, and I’ve seen a shortage of ophthalmologists for the past decade,” she says. “Generally speaking, when residents and fellows finish their training, they tend to move to the coasts—the East Coast, West Coast, or down south to Florida. Here in the Midwest, we’ve really felt the shortage, especially in rural practices, but even in urban, solo-owned practices.”

Read more: https://www.reviewofophthalmology.com/article/contemplating-the-workforce-deficit

Click here to read all the articles in our series:
https://www.reviewofophthalmology.com/issue/2025-year-in-review

An 81-year-old female presented to Wills Eye with a one-month history of painless vision loss in the right eye. She repo...
12/29/2025

An 81-year-old female presented to Wills Eye with a one-month history of painless vision loss in the right eye. She reported sudden onset of vision loss upon waking without associated pain, redness or trauma. The patient also described seeing colorful lights and reported only being able to see out of a “triangle” of vision.

What's going on here? View the clinical findings below. ⬇️

Read the full case in the December issue or online at www.reviewofophthalmology.com/article/december-2025-wills-eye-resident-case-series. 📖



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