The American Journal of Pathology

10/02/2026

Pathogenesis-Driven Advances in Diagnosis and Treatment of Disease. From American Society for Investigative Pathobiology member Dr. Menglu Yang and colleagues from David Geffen School of Medicine at UCLA, Mass General Brigham (Harvard Medical School), and The Ohio State University.

text: https://ajp.amjpathol.org/article/S0002-9440(26)00231-2/fulltext

10/02/2026

The American Journal of Pathology seeks original research for our upcoming theme issue: Organ to Organ Crosstalk in Disease.

Share this opportunity with your network and submit online for free: https://www.editorialmanager.com/ajpa/Default.aspx

10/01/2026

Read the introductory Guest Editorial for this special theme issue from special editors Daisy Shu and Jingjing You.

Front to Back: Pathobiology, Mechanisms, and Innovations in Ocular Disease: https://ajp.amjpathol.org/article/S0002-9440(26)00232-4/fulltext

09/30/2026

: DNA Methylation Dynamics in a Mouse Model of Retinitis Pigmentosa. From American Society for Investigative Pathobiology member D**g Feng Chen and colleagues from Massachusetts Eye and Ear.

Free in the :

Retinitis pigmentosa (RP) is a group of sight-threatening genetic diseases characterized by progressive degeneration of photoreceptors, leading to severe vision loss from childhood to adulthood. With limited treatment options, understanding the molecular mechanisms underlying RP is crucial. Increase...

09/30/2026

The October issue of The American Journal of Pathology is online and features our latest themed articles!

Full issue: https://ajp.amjpathol.org/issue/S0002-9440(25)X0012-2

09/28/2026

: Distinct Role of Dural and Leptomeningeal Macrophages in Maintaining Cerebrospinal Fluid Drainage to Meningeal Lymphatic Vessels. From American Society for Investigative Pathobiology member author Shan Liao and colleagues from the Snyder Institute for Chronic Diseases at the University of Calgary's Cu***ng School of Medicine.

text:

Cerebrospinal fluid (CSF) drains along the perivascular space, known as the glymphatic system, to the meninges, where meningeal lymphatic vessels (MLVs) remove toxic products with excess CSF from the brain. Macrophages are widely present in the leptomeninges and dura mater of meninges. However, whet...

09/24/2026

: Perilipin 2 Mediates Progression of Lung Adenocarcinoma by Modulating Lipid Metabolism. Authors from 帝京大学｜Teikyo University

text:

Perilipin 2 expression is related to poor prognosis of patients with various malignant tumors. It exists on the surface of lipid droplets (LDs), which store lipids that can be used as an energy source during cancer progression. However, the underlying mechanism of lipid metabolism involving LDs in t...

09/22/2026

: HIF-1α-induced astrocytic D-dopachrome tautomerase activates microglial inflammatory response following spinal cord injury.

text:

Spinal cord injury (SCI) often results in severe hypoxia and excessive activation of neuroinflammation, which aggravates neuropathology and neurologic dysfunction. D-dopachrome tautomerase (D-DT), the homolog of macrophage migration inhibitory factor, is a key proinflammatory mediator implicated in....

09/21/2026

- Organ to Organ Crosstalk in Disease

Submission is free: https://www.editorialmanager.com/ajpa/Default.aspx

Deadline: November 30, 2026

Send your work for consideration today!