Pediatric Infectious Disease Journal

02/19/2025

Multiplex RT-PCR demonstrates high sensitivity and negative predictive value for the detection of on-panel pathogens (Biofire FilmArray) in respiratory samples obtained from critically ill children requiring mechanical ventilation.

RT-PCR use may alter antibiotic prescriptions in this population.

Osborne C et al.

polymerase chain reaction (RT-PCR) with bacterial targets is now available for clinical use. We compared the diagnostic performance of tracheal aspirate (TA) multiplex RT-PCR to culture in children requiring MV with suspected lower respiratory tract infection. Methods: This is a secondary analysis o...

02/19/2025

This very first INMIS supplement includes the reports of the 2024 meeting and of the Latin American Symposium held in conjunction with the Latin American Society of Pediatric Infectious Diseases (SLIPE), and covers a range of current topics in the field of maternal and neonatal immunization based on work presented by leading international experts in the field and original work submitted by participants.

An abstract is unavailable.

02/19/2025

Klebsiella michiganensis, a member of the Klebsiella oxytoca complex, is an emerging nosocomial pathogen known to frequently carry plasmids with AMR genes, including carbapenemases.
Using genomics, this study redefined an outbreak alert of K. michiganensis carrying carbapenemase in a pediatric ward in a Spanish hospital.

Lopez-Camacho et al

g a blaVIM carbapenemase in a pediatric ward in a Spanish hospital. Methods: A total of 31 isolates of Verona integron-encoded metallo-β-lactamase (VIM)-carbapenemase K. oxytoca from suspected outbreak cases and unrelated controls from 2015 to 2022 were analyzed. Whole-genome sequencing (both short...

02/02/2025

Article by Ines Taborda et al. reports epidemiology of late pneumoniae resurgence in Portugal; concludes that compared with pre-COVID era, disease severity and EP manifestations did not change, while median age at presentation increased

ary manifestations did not change, while median age at presentation increased....

12/12/2024

Are adolescents and young adults on ALL treatment more vulnerable to invasive bacterial/ fungal infections than pediatric ALL patients?

Read new insights from Trimbour et al. in

the occurrence of bacterial bloodstream infection (BSI) and proven and probable invasive fungal infection (IFI) in AYAs (15–25 years old) and children (1–14 years old) treated for acute lymphoblastic leukemia between January 2013 and December 2020 in 2 French tertiary pediatric and 2 referral ad...

12/12/2024

Elevated plasma (1, 3) β-D-glucan (BDG) level might be a useful predictor for systemic progression of congenital cutaneous candidiasis in neonates.

Watanabe et al.

An abstract is unavailable.

12/07/2024

Are pathogens causative of early- and late-onset neonatal sepsis changing globally?

This latest analysis reports increasing proportion of GN bacteria responsible for serious bacterial infections in infants, suggests revision of current empirical antibiotic recommendations.

Harrison, Dickson, Sharland and Williams. December 2024

ive. We performed a systematic review and meta-analysis to evaluate the contemporary bacterial pathogens responsible for early-onset sepsis (EOS) and late-onset neonatal sepsis (LOS) to ascertain if historical classifications—that guide empirical therapy recommendations based on assumptions around...

09/28/2024

🌟 New insights on managing Paediatric Post-COVID-19 Condition (PPCC)

📑 Discover the latest findings on the management and rehabilitation of children with Paediatric Post-COVID-19 Condition (PPCC), featured in the Pediatric Infectious Disease Journal

PPCC, also known as long COVID in children, is a complex condition with symptoms like fatigue, cognitive difficulties, and mood disturbances. This report highlights the importance of a multidisciplinary approach—focusing on personalized care that prioritizes symptom management, energy pacing, and a gradual return to normal cognitive, physical, and social activities.

Read the full study: https://bit.ly/3N3oBlz

09/24/2024

Clinical Characteristics and Management of Children & Adolescents Hospitalized With

Study in 11 Swiss children hospitals. S. aureus & S. pyogens identified as predominant causative agents.

Editor's pick Weber Sebastian and Heininger Ulrich et al.

hods: This retrospective multicenter study included patients

09/24/2024

Diagnostic Performance of Machine Learning-based Models in Neonatal : A Systematic Review.

Of 19 studies that used 76 ML models: most included birth weight and GA as candidate predictors. Pooled sensitivity 87% and specificity 89%.

Editor's pick.
Kainth D, Prakash S, Sankar JM.

databases using “neonate,” “sepsis” and “machine learning” as search terms. We included studies that developed or validated an ML algorithm to predict neonatal sepsis. Those incorporating automated vital-sign data were excluded. Among 5008 records, 74 full-text articles were screened. Tw...

09/21/2024

🌟 New Research!

📑 Discover a significant study on Pyomyositis in children and adolescents recently published in the Pediatric Infectious Disease Journal.

This multicenter research, conducted across 11 Swiss hospitals, explores a bacterial muscle infection that's often overlooked in temperate regions but is now on the rise.

The findings underscore the importance of early diagnosis and effective treatment to improve patient outcomes.

For those looking to stay informed on the latest in pediatric infectious diseases, this study is essential reading➡️ https://bit.ly/47AQNFL

09/07/2024