11/24/2025
Postpartum hemorrhage (PPH) is still the world’s #1 cause of maternal deaths—especially in low- and middle-income countries. While high-income countries have nearly eliminated deaths from PPH, many women in Africa and South Asia continue to face preventable risks.
A new Special Collection published by the International Journal of Maternal and Child Health and AIDS (IJMA), in collaboration with Concept Foundation, shares powerful new evidence from nine countries on two important medicines:
• Heat-stable carbetocin (HSC) for preventing PPH
• Tranexamic acid (TXA) for treating PPH
Researchers studied 126,882 women, spoke with 678 healthcare providers, and gathered real-world data from 103 facilities across Africa and Asia. The results show that these medicines are safe, effective, feasible to use, and widely accepted—even in areas with limited resources or cold-chain challenges.
This collection is a major step forward in improving maternal health, strengthening health systems, and helping countries move closer to global goals for reducing maternal deaths.
Together, science, partnerships, and implementation research can save lives. 💙