On The Pen With Dave Knapp

12/23/2025

First ever GLP-1 Pill for Obesity Approved!
-Coming in January
-Cash pay $149-$399
-Results as good as injectable wegovy!

https://www.OTPLinks.com

12/22/2025

Oral approved in the USA! Will you be switching or trying for maintenance?

12/22/2025

2026 is here!

12/22/2025

You’ve been asking:
Here’s the latest I have on the Zepbound Savings Card

https://www.OTPLinks.com

12/21/2025

savings card 2026 : comment “Zepbound savings card” for the latest!

12/19/2025

and skin pain. Many on report the same. Have you experienced this?

12/18/2025

has announced that they have filed for approval of next gen if approved it will be the fist Amylin agonist approved for obesity and offer a new pathway for weight management!

12/18/2025

Comment: “Details” for the full article!

12/18/2025

Tirzepatide Mounjaro did not show cardiovascular superiority versus dulaglutide Trulicity in a large outcomes trial in people with type 2 diabetes and established heart disease.

It did meet noninferiority, which means cardiovascular safety is confirmed, but it did not outperform a GLP-1 receptor agonist that already has proven heart protection.

This keeps reinforcing a pattern we have now seen across multiple cardiovascular outcomes trials.
Straight GLP-1 receptor agonism consistently reduces major adverse cardiovascular events.
Dual incretin and next generation therapies deliver incredible weight loss and A1C reduction, but clear superiority on hard cardiac outcomes has not yet shown up.

This does not mean tirzepatide failed.
It means the bar for beating proven GLP-1 therapies on heart outcomes is extremely high.

If you live with obesity, type 2 diabetes, or cardiovascular disease, this distinction matters for coverage, prescribing, and long term care decisions.

Save this.
Share this.
Send this to the person who keeps saying weight loss automatically equals heart protection.

12/17/2025

Insurance tips: edition.

12/17/2025

FDA issues another warning letter to Novo over filthy Indiana facility.

The same Indiana that has two reps introducing bills about the safety of compounded meds.

Rich.

Comment: “Sign” to sign the petition opposing this legislation.

12/16/2025

Will be available compounded?