David Nicklaus, St. Louis Post-Dispatch

David Nicklaus, St. Louis Post-Dispatch David Nicklaus, semi-retired but still writing, has covered St. Louis business for 4 decades.

In a decade, GiftAMeal went from student startup to successful exit.
05/11/2026

In a decade, GiftAMeal went from student startup to successful exit.

The company uses restaurant goers' social media posts to generate donations to a food bank.

AI is eliminating many of the entry-level programming jobs that LaunchCode trains people for. The St. Louis organization...
05/01/2026

AI is eliminating many of the entry-level programming jobs that LaunchCode trains people for. The St. Louis organization has responded by launching Hire Human, a series of courses that prepare students for careers in AI.

This year, the goal is to place 250 Hire Human graduates in jobs along with 250 graduates from the traditional software development track.

83% of quartz used in countertops comes from abroad, so a tariff would hurt the small businesses that install them, and ...
04/12/2026

83% of quartz used in countertops comes from abroad, so a tariff would hurt the small businesses that install them, and would put upward pressure on new-home prices.

Home builders also have raised concerns about the effect of a big price increase for quartz, a popular building material

Missouri legislators have introduced a dozen bills that aim to regulate AI. Some address important concerns but others s...
01/20/2026

Missouri legislators have introduced a dozen bills that aim to regulate AI. Some address important concerns but others seem based on sci-fi movie fears.

A couple of bills aim to declare AI systems “non-sentient” and prohibit them from marrying or serving as corporate officers.

After three big up years, and with a heavy focus on artificial intelligence plays, the stock market is as top-heavy as i...
12/31/2025

After three big up years, and with a heavy focus on artificial intelligence plays, the stock market is as top-heavy as it has ever been.

Just 20 companies now account for nearly half of the S&P 500 index's total value

BioGenerator has invested $50 million in startups but managing director Jim McCarter says it's not enough. The nonprofit...
12/09/2025

BioGenerator has invested $50 million in startups but managing director Jim McCarter says it's not enough. The nonprofit is launching two for-profit venture capital funds to "quadruple down" on St. Louis' life-sciences industry.

BioGenerator plans to 'quadruple down' on St. Louis biotech startups

STL startup Wugen has a promising cell treatment for highly deadly forms of leukemia and lymphoma, meeting "a huge unmet...
10/06/2025

STL startup Wugen has a promising cell treatment for highly deadly forms of leukemia and lymphoma, meeting "a huge unmet medical need."

Wugen has become a standout among St. Louis biotech startups. It has raised more than $300 million in capital since 2018 and employs about 35 people.

The IN2 incubator, which has provided a boost to 10 St. Louis ag startups, is changing its name to HARVEST AgTech and mo...
09/23/2025

The IN2 incubator, which has provided a boost to 10 St. Louis ag startups, is changing its name to HARVEST AgTech and moving its HQ from Colorado to STL.

The former Wells Fargo Innovation Incubator, known as IN2, will now be called HARVEST AgTech and run by Yield Lab Institute, an affiliate of Creve Coeur investment firm Yield Lab.

Alex Quinn sold his first startup at age 23. He now heads Authentic Interactions, which lets people produce a holographi...
08/25/2025

Alex Quinn sold his first startup at age 23. He now heads Authentic

Interactions, which lets people produce a holographic "twin" that's able to carry on a conversation

“We can be a $1 billion artificial intelligence company that's known as one of the best AI companies in the world, focused on authenticity and safety.”

AGs accuse Wall Street giants of conspiring to kill the coal industry, but there's a simpler reason why production is do...
07/28/2025

AGs accuse Wall Street giants of conspiring to kill the coal industry, but there's a simpler reason why production is down: Power plants are burning less of the stuff.

Coal's economic challenges forced Peabody and several competitors into bankruptcy in recent years.

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