NEJM Clinician

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NEJM Clinician is a new digital resource designed to help physicians quickly and efficiently stay informed of the latest clinical advances with curated, summarized and contextualized clinical research and guidelines, along with NEJM content.

06/24/2026

Editor-in-Chief Raja-Elie Abdulnour, MD, shares some key results of a recent analysis of a VA database on the relation between GLP-1s and pancreatitis.

Oxybutynin is commonly used for overactive bladder and for hot flashes in women. Researchers assessed whether it could a...
06/23/2026

Oxybutynin is commonly used for overactive bladder and for hot flashes in women. Researchers assessed whether it could also help with hot flashes among men receiving androgen-deprivation therapy (ADT) for prostate cancer.

A recent CDC study examines four cases of tetanus in unvaccinated children. In some cases, postexposure prophylaxis was ...
06/22/2026

A recent CDC study examines four cases of tetanus in unvaccinated children. In some cases, postexposure prophylaxis was also declined.

In 2025, the CDC shifted its recommendation from universal birth-dose hepatitis B virus vaccination to “individual-based...
06/21/2026

In 2025, the CDC shifted its recommendation from universal birth-dose hepatitis B virus vaccination to “individual-based decision-making” for infants born to women who screen negative for hepatitis B surface antigen. Ann Cheung, MD, MBA, MS, summarizes two new studies that help gauge the potential consequences: https://jwat.ch/4xt6Imc

Clinicians have long debated the ideal resuscitation fluid for adult patients, and the choice is even less clear for chi...
06/20/2026

Clinicians have long debated the ideal resuscitation fluid for adult patients, and the choice is even less clear for children. A recent trial in The New England Journal of Medicine tries to shed some light on this area.

Cardiovascular disease remains the leading cause of death among women worldwide. What factors contribute to the problem?...
06/19/2026

Cardiovascular disease remains the leading cause of death among women worldwide. What factors contribute to the problem? Dr. Kathleen Finn examines a recent review: https://jwat.ch/4aGJ6R2

Does initial diuretic dose matter in heart failure exacerbation? Higher doses might shorten hospital length of stay and ...
06/18/2026

Does initial diuretic dose matter in heart failure exacerbation? Higher doses might shorten hospital length of stay and prevent readmissions.

"These data support my practice of initially using high-dose diuretics in patients admitted for acute HF exacerbations," writes Dr. Daniel Dressler.

Frail older adults have a worse prognosis after acute coronary syndromes, yet reliable data have been lacking to determi...
06/17/2026

Frail older adults have a worse prognosis after acute coronary syndromes, yet reliable data have been lacking to determine their optimal management.

Suspected drug-induced pancreatitis was rare but more common in patients taking GLP-1 agonists than sulfonylureas, a rec...
06/16/2026

Suspected drug-induced pancreatitis was rare but more common in patients taking GLP-1 agonists than sulfonylureas, a recent analysis of a VA database finds.

Only 1 of 1500 adrenal incidentalomas discovered on contrast-enhanced CT was subsequently found to be malignant. "This s...
06/15/2026

Only 1 of 1500 adrenal incidentalomas discovered on contrast-enhanced CT was subsequently found to be malignant. "This study confirms that small adrenal incidentalomas are nearly always benign," writes Allan S. Brett, MD. Read more: https://jwat.ch/4ocU46m

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