NEJM Clinician

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NEJM Clinician is a new digital resource designed to help physicians quickly and efficiently stay informed of the latest clinical advances with curated, summarized and contextualized clinical research and guidelines, along with NEJM content.

Editor's Pick: Among infants admitted to intensive care during their first RSV season, those recently given nirsevimab w...
12/26/2025

Editor's Pick: Among infants admitted to intensive care during their first RSV season, those recently given nirsevimab were significantly less likely to have RSV infection.

Some have postulated that very low diastolic blood pressure (DBP) increases the risk for adverse cognitive outcomes. Res...
12/25/2025

Some have postulated that very low diastolic blood pressure (DBP) increases the risk for adverse cognitive outcomes. Researchers take a closer look at the relationship between treated DBP and cognitive function.

Less is more with dialysis in patients with severe acute kidney injury.
12/24/2025

Less is more with dialysis in patients with severe acute kidney injury.

Subacromial decompression surgery for subacromial pain syndrome continues to be recommended and performed in high volume...
12/23/2025

Subacromial decompression surgery for subacromial pain syndrome continues to be recommended and performed in high volume. Now, a randomized trial reports 10-year results following its negative 2- and 5-year results.

Current guidelines recommend either itraconazole or voriconazole as first-line therapy for chronic pulmonary aspergillos...
12/22/2025

Current guidelines recommend either itraconazole or voriconazole as first-line therapy for chronic pulmonary aspergillosis (CPA), but direct head-to-head comparisons are lacking.

When we dialyze hemodynamically stable patients with AKI, should we avoid the thrice-weekly approach? 🤔
12/22/2025

When we dialyze hemodynamically stable patients with AKI, should we avoid the thrice-weekly approach? 🤔

A recent study examined how often elevated prostate-specific antigen (PSA) levels drop by the next annual prostate cance...
12/21/2025

A recent study examined how often elevated prostate-specific antigen (PSA) levels drop by the next annual prostate cancer screening.

Repeating blood cultures is unwarranted in asymptomatic patients after completion of therapy for bacterial endocarditis.
12/20/2025

Repeating blood cultures is unwarranted in asymptomatic patients after completion of therapy for bacterial endocarditis.

Incorporating this bedside clinical information early in septic shock treatment might be a win for patients.
12/20/2025

Incorporating this bedside clinical information early in septic shock treatment might be a win for patients.

Winter's first cold snap has hit Boston, and Associate Editor Paul Sax, MD, is marking the occasion with another infecti...
12/19/2025

Winter's first cold snap has hit Boston, and Associate Editor Paul Sax, MD, is marking the occasion with another infectious diseases link-o-rama.

Should patients with normal ejection fraction take beta-blockers after myocardial infarction? Not in patients without ot...
12/18/2025

Should patients with normal ejection fraction take beta-blockers after myocardial infarction? Not in patients without other indications for the drugs, a new analysis in The New England Journal of Medicine suggests.

In patients with unprovoked venous thromboembolism, guidelines recommend continuing oral anticoagulation beyond 3-6 mont...
12/17/2025

In patients with unprovoked venous thromboembolism, guidelines recommend continuing oral anticoagulation beyond 3-6 months. A recent study compared continuing and stopping anticoagulation in a real-world population.

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