NEJM Journal Watch

NEJM Journal Watch Over 100 physician-editors regularly survey more than 250 medical journals and deliver only the most important clinical research findings.
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Results of the KEYNOTE-689 trial indicate that clinicians can begin using immune checkpoint inhibitors perioperatively i...
07/31/2025

Results of the KEYNOTE-689 trial indicate that clinicians can begin using immune checkpoint inhibitors perioperatively in surgically treated patients with squamous cell carcinoma of the head and neck, writes Dr. Hyunseok Kang. https://jwat.ch/4fePUGA

"Immune responses to residual antigen might help explain some of the clinical and laboratory findings in people with pos...
07/31/2025

"Immune responses to residual antigen might help explain some of the clinical and laboratory findings in people with post-Lyme arthritis," writes Dr. Anthony Komaroff about a recent study. https://jwat.ch/4l0Ul9e

Risk for cefepime-induced neurotoxicity was elevated in hospitalized patients with febrile neutropenia who were receivin...
07/30/2025

Risk for cefepime-induced neurotoxicity was elevated in hospitalized patients with febrile neutropenia who were receiving CAR T-cell therapy. https://jwat.ch/3GGaF1q

Researchers examined the risk for liver enzyme abnormalities with cannabidiol dosages typically used by consumers of unp...
07/30/2025

Researchers examined the risk for liver enzyme abnormalities with cannabidiol dosages typically used by consumers of unprescribed products. https://jwat.ch/3IPPlHg

Can Radiation Therapy Be Omitted in Low-Risk Breast Cancer?A cohort study showed low recurrence rates in older women tre...
07/29/2025

Can Radiation Therapy Be Omitted in Low-Risk Breast Cancer?

A cohort study showed low recurrence rates in older women treated with surgery and endocrine therapy alone. https://jwat.ch/4m5JRGO

Who gets sent to the ID clinic? Cases generally fall into one of four broad categories, writes Dr. Paul Sax. https://jwa...
07/29/2025

Who gets sent to the ID clinic? Cases generally fall into one of four broad categories, writes Dr. Paul Sax. https://jwat.ch/3GNSua6

Rheumatoid arthritis is a known risk factor for carpal tunnel syndrome, but could carpal tunnel be an early manifestatio...
07/28/2025

Rheumatoid arthritis is a known risk factor for carpal tunnel syndrome, but could carpal tunnel be an early manifestation of RA? https://jwat.ch/4lNb6pW

Two research groups used population genetic data to identify connections between endogenous herpesvirus 6 and health ris...
07/27/2025

Two research groups used population genetic data to identify connections between endogenous herpesvirus 6 and health risks, finding that it might predispose people to angina and autoimmune diseases. https://jwat.ch/415vw50

Does long-term oxygen therapy lower healthcare use for patients with chronic lung diseases? https://jwat.ch/4fcjbC8
07/26/2025

Does long-term oxygen therapy lower healthcare use for patients with chronic lung diseases? https://jwat.ch/4fcjbC8

Some patients with Guillain–Barré syndrome continue to progress after treatment and are unable to walk 6 months after on...
07/25/2025

Some patients with Guillain–Barré syndrome continue to progress after treatment and are unable to walk 6 months after onset. Does a second course of intravenous immunoglobulin help? https://jwat.ch/3IFwqim

What determines long-term shedding of non-typhoidal Salmonella? A Norwegian study identified several risk factors. https...
07/25/2025

What determines long-term shedding of non-typhoidal Salmonella? A Norwegian study identified several risk factors. https://jwat.ch/4m8k1lk

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