A monthly publication that provides coverage of medical care, cosmetic advancements, and practice ma
Practical Dermatology delivers real-world medical, cosmetic, and practice management advice for dermatologists and dermatology physician assistants. Readers recognize that Practical Dermatology’s unique editorial style cuts to the heart of the issues with expert opinions, timely coverage, clinical summaries, and high-quality supportive graphics. Whether readers are looking for insights on the late
st aesthetic interventions, tips to manage difficult medical conditions, or advice to grow their practice, they’ll find reliable answers in Practical Dermatology.
Operating as usual
Nonuremic calciphylaxis is a complex diagnosis. The condition presents as vessel calcification and thrombosis in the presence of normal kidney function. Here, the authors present a case of warfarin-induced nonuremic calciphylaxis of the lower extremities, with superimposed cellulitis. They also provide a comprehensive overview of its diagnosis and management based on updated data from the literature. https://bit.ly/3LsxipI
Psoriasis is a chronic autoimmune inflammatory skin condition that affects more than 6.9 million people in the United States. Like cardiovascular conditions, cancer, and depression, can have a severe impact on quality of life (QOL). There is currently no cure for psoriasis, but several treatment options are available for its symptoms that may help improve patients’ QOL, particularly when sensitive areas are involved. Continue reading: https://bit.ly/405tlM1
A novel rare skin mutation in ABCA12 gene is linked to Harlequin Ichthyosis, according to a new case study published in Frontiers in Pediatrics.
Harlequin ichthyosis (HI) is a severe genetic skin disorder characterized by thick white, brown, or dark brown patches on the skin covering a newborn's entire body. HI has a low incidence of 1 per 300,000 live births but comes with the highest mortality rate among skin conditions.
Harlequin ichthyosis is a severe genetic skin disorder characterized by thick white, brown, or dark brownpatches on the skin covering a newborn's entire body.
Nail enamel or polish is perhaps the most common nail cosmetic. It was introduced in the 1920s when nitrocellulose was developed as a military explosive. Few US plants manufacture nail polish owing to the explosive process of creating nitrocellulose from cellulose fiber, wood pulp, and nitric acid.
The use of nail cosmetics is widespread; there is a nail salon in almost every strip mall in the United States. It therefore behooves dermatologists to familiarize themselves with the products, techniques, and issues associated with the most recently released nail cosmetics. https://bit.ly/41T8VaN
The Alzheimer’s disease memantine effectively reduces symptoms of adults with trichotillomania and skin-picking disorder also known as excoriation disorder, new research shows. https://bit.ly/3YwSrC7
An open-ended conversation with patients is essential when discussing psoriasis treatment options. https://bit.ly/3JmVxoc
If you think obtaining a prior authorization is a dreadful task, what happens when the submission is denied? Sure, you could throw your hands up and say you did what you could for the patient, but health care is about helping patients, right?
Countless new drug therapies are in development and coming to market, and more than half are or specialty medications. Biologic coordinators can help bridge the gap between you—the clinician prescribing therapy—and your patients receiving specialty medications. Continue reading: https://bit.ly/3JeOy0m
Why are su***de and burnout so prevalent among professionals dedicated to health and healing?
We don’t have a simple answer because the problems are complex and multifaceted. In The Truth About Burnout, Christina Maslach and Michael Leiter write that burnout “represents an erosion in values, dignity, spirit, and will—an erosion of the human soul.”
In my opinion, the degradation of physician autonomy erodes the soul more than anything else in our cumbersome health care system. https://bit.ly/3miJJKw
are making inroads into the treatment of , but their US availability has been limited by patent protections. In 2023, if patent issues are resolved, the landscape of psoriasis treatment will expand. Continue reading: https://bit.ly/3Ydm9Ms
Patients with high-risk who received both before and after surgery had a significantly lower risk of their cancer recurring than patients who received the drug only after surgery.
These results, published today in NEJM, are from a research study led by the SWOG Cancer Research Network, a cancer clinical trials group funded by the National Cancer Institute.
Starting pembrolizumab before surgery instead of waiting until after surgery significantly improves the outlook for patients with stage III-IV melanoma.
Why are su***de and burnout so prevalent among professionals dedicated to health and healing?
One dermatologist’s quest to protect physicians from moral injury.
A lack of representation for underserved ethno-racial groups in clinical data and research is an underlying factor contributing to physicians’ challenges with effectively diagnosing and treating psoriasis in patients with diverse skin tones.
A lack of representation for underserved ethno-racial groups in clinical data and research is an underlying factor contributing to physicians’ challenges with effectively diagnosing and treating psoriasis in patients with diverse skin tones.
It is perhaps unsurprising then that, as a group, are highly focused on efficiency and productivity, even outside of the clinic. One area that deserves a high degree of scrutiny is meetings. With the increasing bureaucratic burdens in medicine, meetings—and here we refer to the administrative type rather than an educational conference—have become a fixture of modern life for , a far cry from the nostalgic vision of a rustic doctor working alone after hanging out a shingle. Team meetings, committee-meetings, hospital-mandated meetings, research meetings, educational meetings—meetings are unavoidable regardless of one’s role and focus in . https://bit.ly/3KNwxr4
See Full Prescribing Information: https://bit.ly/SOTYKTUpi
SOTYKTU (deucravacitinib) is a once-daily oral treatment. Learn more about dosing: http://bit.ly/3BVghPu
This ad is brought to you by Bristol Myers Squibb.
What's new in your practice?
In each issue, Practical Dermatology® magazine taps top dermatologists to ask about the newest cosmeceuticals they are offering to patients. This issue, Dr. Claire Wolinksy, a in NYC, shares how ISDIN’s latest launch, Melaclear Advanced, is giving pigment a run for its money! Read about more of her suggestions: https://bit.ly/3KFOrvU
and filler injections continue to top the list of most in-demand treatments for patients. With many safe and effective options available, new and emerging products are also showing promise. Nashville, Tenn.-based Michael Gold, MD shares his insights about trends, what’s new, and what potential developments he’s excited about. https://bit.ly/3lgS54S
Apremilast may be an “incredibly promising” treatment for alcohol use disorder, according to a new study in The Journal of Clinical Investigation.
On average, the people who took reduced their alcohol intake by more than half — from five drinks per day to two.
People who took apremilast reduced their alcohol intake by more than half — from five drinks per day to two.
Energy-based devices have revolutionized cosmetic , and the already hot category is experiencing a growth spurt.
Todd Schlesinger, MD, founder and medical director of the Dermatology & Laser Center of Charleston as well as the Clinical Research Center of the Carolinas sat down with Practical Dermatology® magazine to discuss his go-to devices and the growing role they play in his practice. https://bit.ly/41lnlAi
In this brief article, we aim to outline best practices and principles for maximizing efficiency in meetings from a perspective. The goal is not to criticize well-intentioned efforts but to revisit the purpose of meetings and to offer constructive and practical suggestions to improve meeting efficiency. Ahead, we share personal experiences, anecdotes, and a variety of opinions, supplemented with external evidence from the literature, where available. https://bit.ly/3XNHo78
Notalgia paresthetica—a nerve disorder characterized by a persistent itch in the upper back—is a common and underdiagnosed condition worldwide. To date, there are no U.S. FDA-approved treatments specifically targeting this disorder.
But a new study in the The New England Journal of Medicine suggests that patients experiencing the moderate-to-severe itching associated with the disorder could potentially get relief with oral difelikefalin. The research was led by investigators at the Icahn School of Medicine at Mount Sinai. https://bit.ly/3S80xzH
Cetaphil announced it is launching a new initiative this month that aims to raise awareness of the connection between our clothes and skin. The initiative includes a partnership with Hillary Taymour, designer and founder of fashion house Collina Strada, and board-certified dermatologist at Spring Street Dermatology, Sapna Rao Palep, MD, Dermatologist - Leading Physicians of the World , MD.
Cetaphil announced it is launching a new initiative this month that aims to raise awareness of the connection between our clothes and skin. The initia
See Full Prescribing Information: https://bit.ly/SOTYKTUpi
SOTYKTU (deucravacitinib) has a unique mechanism of action. Discover more MOA information here: http://bit.ly/3v8UHTW
This ad is brought to you by Bristol Myers Squibb.
Dermavant Sciences has completed patient enrollment in its ADORING 1 and 2 Phase 3 clinical trials of VTAMA (tapinarof) cream, 1% for the topical treatment of atopic dermatitis (AD) in adults and children as young as 2 years old. https://bit.ly/3S0chUS
The U.S. General Services Administration has recommended DermTech‘s foundational assay included in the DermTech Melanoma Test (DMT) for coverage by the Veterans Health Administration (VHA), according to a company news release.
This coverage recommendation makes the foundational assay of the DMT available to the VHA’s over 9 million enrolled veterans.
The U.S. General Services Administration has recommended DermTech‘s foundational assay included in the DermTech Melanoma Test (DMT) for coverage
See Full Prescribing Information: https://bit.ly/SOTYKTUpi
SOTYKTU (deucravacitinib) is a once-daily treatment option for appropriate patients. See the efficacy and safety data >> http://bit.ly/3VmFmtw
This ad is brought to you by Bristol Myers Squibb.
Longer-term treatment with povorcitinib 75 mg resulted in sustained and durable efficacy across all treatment arms in a phase 2 study of hidradenitis suppurativa (HS) patients.
Povorcitinib is an oral JAK1 inhibitor. These data were presented as an oral presentation at the 12th Conference of the European Hidradenitis Suppurativa Foundation, held from February 8 to 10, 2023, in Florence, Italy.
Longer-term treatment with povorcitinib 75 mg resulted in sustained and durable efficacy across all treatment arms in a phase 2 study.
See Full Prescribing Information: https://bit.ly/SOTYKTUpi
SOTYKTU (deucravacitinib) is a once-daily treatment option for appropriate patients. See the efficacy and safety data >> http://bit.ly/3VmFmtw
This ad is brought to you by Bristol Myers Squibb.
This (April), the National Rosacea Society (NRS) is highlighting the importance of consistency and patience when trying new therapies.
“Rosacea has no cure, but the signs and symptoms can go into remission through a combination of medical therapy and lifestyle changes,” says Dr. Estee Williams, assistant clinical professor of at Mount Sinai Medical Center, in a news release. “The timeline to achieve remission will be different for each individual depending on the disease presentation and severity. The key is consistency and patience."
Read more: https://bit.ly/3IbMd5T
Despite fears of a looming recession, the market for treatments remains strong, and the prospect of new entries is keeping consumer demand healthy. As a new year starts, it’s smart to consider promoting some new options to drive consumer excitement and volume. Here, we report five hot trends from Wendy Lewis & Co Ltd: https://bit.ly/3x3gcql
Neurotoxin and filler injections continue to top the list of most in-demand treatments for aesthetic patients. With many safe and effective options available, new and emerging products are also showing promise. Nashville, TN-based Michael H. Gold, MD shares his insights about trends, what’s new, and what potential developments he’s excited about. https://bit.ly/3lgS54S
Bio-Oil USA is rolling out a month-long campaign in celebration of February's Body Positivity Month to encourage self-love, promote body confidence, and highlight the role that Bio-Oil plays in helping people to love their stretch marks due to pregnancy, to scars from surgical procedures.
Bio-Oil is partnering with a diverse roster of social media influencers to share how they view and take care of their bodies – and the strength they represent – on TikTok and Instagram.
Darier disease (DD) is a rare, autosomal dominant disorder with an approximated prevalence of one to two cases per 100,000 people. It is caused by mutations in the ATP2A2 gene coding for the SarcoEndoplasmic Reticulum Calcium-ATPase 2 (SERCA2) pump, which leads to desmosome protein dysfunction and abnormal keratinization. Approximately 10% of cases represent the localized form of DD, causing a mosaic pattern of skin involvement. Several variants of localized DD have been reported, including unilateral, zosteriform, segmental, and linear.
Here, Lacey Zimmerman, MD; Neha Chandan MD, MPH; and Sheryl Hoyer, MD, present a rare case of linear DD: https://bit.ly/3HACBA3
Avero Diagnostics announced the US launch of AMBLor, a laboratory test for the identification of early-stage melanomas at low risk of progression.
AMBLor technology identifies the presence of two prognostic biomarker proteins, AMBRA1 and loricrin, in the skin overlying the tumor, according to Avero.
Avero Diagnostics announced the US launch of AMBLor, a laboratory test for the identification of early-stage melanomas at low risk of progression.
New biomarkers to improve detection and avoid delays in treatment are being developed by researchers at the University of South Australia.
“ exhibit a wide range of sizes, shapes and growth, which can resemble numerous benign and other malignant skin lesions,” says UniSA PhD candidate Giang Lam in a new paper published in Molecular Diagnosis and Therapy.
The new detection methods based on abnormal markers in the endosomal system, which flags melanoma growth.
Medical video games increase the competence and clinical decision-making of practicing physicians, a new study by LEVEL EX shows. Doctors not only showed clinical improvement while playing the games, but also demonstrated improvement in clinical decision making long after gameplay. https://bit.ly/3l5ZGDf
The Bundy Group wanted to analyze the key questions and unpack the positives and considerations of accepting an unsolicited offer versus running a competitive process managed by an investment banker. Explore them here: https://bit.ly/3Yy82lB
Slightly more than 7% of adults and nearly 11% of kids had in 2021, according to two new reports in the CDC ’s National Center for Health Statistics Data Brief.
While the new research wasn’t designed to determine if eczema is on the rise, the condition does appear to be more prevalent than in past years. Continue reading: https://bit.ly/3JvAPml
The phenomenon of lanolin allergenicity is the focus of the Contact Allergen of the Year article in Dermatitis.
Lanolin and its derivatives are widely used in cosmetics and pharmaceuticals designed for topical use on skin, lips, nails, and hair, and as an ocular emollient. They also have many industrial uses. Still, lanolin’s allergenicity remains controversial, and appropriate patch testing to detect lanolin allergy remains a topic of dispute.
The phenomenon of lanolin allergenicity is the focus of the Contact Allergen of the Year article in Dermatitis. Lanolin and its der
BCC is the most common cancer in the US. How can the best treatment pathway for individual patients be determined? Check out this multimedia and to learn more! View here: https://bit.ly/3GGOk0T
Bioprinted artificial skin can be used in cosmetics and drug testing, a new study shows.
For the study, researchers compared the conventional mimetic model based on manual pipetting with extrusion bioprinting, which “allows the in vitro reconstruction of a more relevant and representative model of human skin.”
The biomimetic material can be produced on a large scale, reducing animal testing by the cosmetics and pharmaceutical industries.
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Don’t miss this week’s DermWireTV: FDA has approved Zoryve from Arcutis Biotherapeutics for the treatment of plaque #psoriasis, including intertriginous areas, in patients 12 years of age or older. The novel formulation of roflumilast cream 0.3% is indicated for once-daily application. Stelara (ustekinumab) from Janssen is now approved for the treatment of active psoriatic arthritis in pediatric patients six years of age and older. Determi-Nation, supported by Janssen, is described as a health movement comprised of diverse health care providers, patients and advocates united to develop solutions to help people of color with psoriatic disease receive equitable and high-quality medical care. DermPA Lauren Miller, MS, PA-C is now president of the SDPA Board of Directors. Watch the full episode: https://practicaldermatology.com/series/dermwire-tv/dermwiretv-zoryve-approved-new-sdpa-president-project-determi-nation-stelara-for-pediatric-psa?c4src=news:featured #dermatology #practicaldermatology #psoriaticarthritisawareness #psoriasisactionmonth #dermpanp #dermpa #skinofcolor #diversityandinclusion
With the launch of Eskata & acquisition of Rhofade, Aclaris is making a mark in #aesthetics and #dermatology. In the new Aesthetics Insider, CEO & President Neal Walker, DO speaks with host Dr. Steve Dayan about the company. Watch now: https://hubs.ly/H0fRxT_0
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