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Practical Dermatology

Practical Dermatology A monthly publication that provides coverage of medical care, cosmetic advancements, and practice ma

Practical Dermatology delivers real-world medical, cosmetic, and practice management advice for dermatologists and dermatology physician assistants. Readers recognize that Practical Dermatology’s unique editorial style cuts to the heart of the issues with expert opinions, timely coverage, clinical summaries, and high-quality supportive graphics. Whether readers are looking for insights on the late

st aesthetic interventions, tips to manage difficult medical conditions, or advice to grow their practice, they’ll find reliable answers in Practical Dermatology.

Operating as usual

Nonuremic calciphylaxis is a complex diagnosis. The condition presents as vessel calcification and thrombosis in the pre...
03/13/2023

Nonuremic calciphylaxis is a complex diagnosis. The condition presents as vessel calcification and thrombosis in the presence of normal kidney function. Here, the authors present a case of warfarin-induced nonuremic calciphylaxis of the lower extremities, with superimposed cellulitis. They also provide a comprehensive overview of its diagnosis and management based on updated data from the literature. https://bit.ly/3LsxipI

Psoriasis is a chronic autoimmune inflammatory skin condition that affects more than 6.9 million people in the United St...
03/12/2023

Psoriasis is a chronic autoimmune inflammatory skin condition that affects more than 6.9 million people in the United States. Like cardiovascular conditions, cancer, and depression, can have a severe impact on quality of life (QOL). There is currently no cure for psoriasis, but several treatment options are available for its symptoms that may help improve patients’ QOL, particularly when sensitive areas are involved. Continue reading: https://bit.ly/405tlM1

A novel rare skin mutation in ABCA12 gene is linked to Harlequin Ichthyosis, according to a new case study published in ...
03/10/2023
Novel Rare Mutation in ABCA12 Gene linked to HI - Practical Dermatology

A novel rare skin mutation in ABCA12 gene is linked to Harlequin Ichthyosis, according to a new case study published in Frontiers in Pediatrics.

Harlequin ichthyosis (HI) is a severe genetic skin disorder characterized by thick white, brown, or dark brown patches on the skin covering a newborn's entire body. HI has a low incidence of 1 per 300,000 live births but comes with the highest mortality rate among skin conditions.

Harlequin ichthyosis is a severe genetic skin disorder characterized by thick white, brown, or dark brownpatches on the skin covering a newborn's entire body.

Nail enamel or polish is perhaps the most common nail cosmetic. It was introduced in the 1920s when nitrocellulose was d...
03/09/2023

Nail enamel or polish is perhaps the most common nail cosmetic. It was introduced in the 1920s when nitrocellulose was developed as a military explosive. Few US plants manufacture nail polish owing to the explosive process of creating nitrocellulose from cellulose fiber, wood pulp, and nitric acid.

The use of nail cosmetics is widespread; there is a nail salon in almost every strip mall in the United States. It therefore behooves dermatologists to familiarize themselves with the products, techniques, and issues associated with the most recently released nail cosmetics. https://bit.ly/41T8VaN

The Alzheimer’s disease memantine effectively reduces symptoms of adults with trichotillomania and skin-picking disorder...
03/09/2023

The Alzheimer’s disease memantine effectively reduces symptoms of adults with trichotillomania and skin-picking disorder also known as excoriation disorder, new research shows. https://bit.ly/3YwSrC7

An open-ended conversation with patients is essential when discussing psoriasis treatment options. https://bit.ly/3JmVxo...
03/07/2023

An open-ended conversation with patients is essential when discussing psoriasis treatment options. https://bit.ly/3JmVxoc

If you think obtaining a prior authorization is a dreadful task, what happens when the submission is denied? Sure, you c...
03/06/2023

If you think obtaining a prior authorization is a dreadful task, what happens when the submission is denied? Sure, you could throw your hands up and say you did what you could for the patient, but health care is about helping patients, right?

Countless new drug therapies are in development and coming to market, and more than half are or specialty medications. Biologic coordinators can help bridge the gap between you—the clinician prescribing therapy—and your patients receiving specialty medications. Continue reading: https://bit.ly/3JeOy0m

Why are su***de and burnout so prevalent among professionals dedicated to health and healing?We don’t have a simple answ...
03/05/2023

Why are su***de and burnout so prevalent among professionals dedicated to health and healing?

We don’t have a simple answer because the problems are complex and multifaceted. In The Truth About Burnout, Christina Maslach and Michael Leiter write that burnout “represents an erosion in values, dignity, spirit, and will—an erosion of the human soul.”

In my opinion, the degradation of physician autonomy erodes the soul more than anything else in our cumbersome health care system. https://bit.ly/3miJJKw

 are making inroads into the treatment of , but their US availability has been limited by patent protections. In 2023, i...
03/03/2023

are making inroads into the treatment of , but their US availability has been limited by patent protections. In 2023, if patent issues are resolved, the landscape of psoriasis treatment will expand. Continue reading: https://bit.ly/3Ydm9Ms

Patients with high-risk  who received  both before and after surgery had a significantly lower risk of their cancer recu...
03/02/2023
Landmark Data: Neoadjuvant Pembrolizumab Improves Outcomes for High-risk Melanoma Patients - Practical Dermatology

Patients with high-risk who received both before and after surgery had a significantly lower risk of their cancer recurring than patients who received the drug only after surgery.

These results, published today in NEJM, are from a research study led by the SWOG Cancer Research Network, a cancer clinical trials group funded by the National Cancer Institute.

Starting pembrolizumab before surgery instead of waiting until after surgery significantly improves the outlook for patients with stage III-IV melanoma.

A lack of representation for underserved ethno-racial groups in clinical data and research is an underlying factor contr...
03/01/2023
Redefining the Discourse: Psoriasis in Diverse Skin Tones - Practical Dermatology

A lack of representation for underserved ethno-racial groups in clinical data and research is an underlying factor contributing to physicians’ challenges with effectively diagnosing and treating psoriasis in patients with diverse skin tones.

A lack of representation for underserved ethno-racial groups in clinical data and research is an underlying factor contributing to physicians’ challenges with effectively diagnosing and treating psoriasis in patients with diverse skin tones.

It is perhaps unsurprising then that, as a group,  are highly focused on efficiency and productivity, even outside of th...
02/28/2023

It is perhaps unsurprising then that, as a group, are highly focused on efficiency and productivity, even outside of the clinic. One area that deserves a high degree of scrutiny is meetings. With the increasing bureaucratic burdens in medicine, meetings—and here we refer to the administrative type rather than an educational conference—have become a fixture of modern life for , a far cry from the nostalgic vision of a rustic doctor working alone after hanging out a shingle. Team meetings, committee-meetings, hospital-mandated meetings, research meetings, educational meetings—meetings are unavoidable regardless of one’s role and focus in . https://bit.ly/3KNwxr4

What's new in your practice?In each issue, Practical Dermatology® magazine taps top dermatologists to ask about the newe...
02/26/2023

What's new in your practice?
In each issue, Practical Dermatology® magazine taps top dermatologists to ask about the newest cosmeceuticals they are offering to patients. This issue, Dr. Claire Wolinksy, a in NYC, shares how ISDIN’s latest launch, Melaclear Advanced, is giving pigment a run for its money! Read about more of her suggestions: https://bit.ly/3KFOrvU

 and filler injections continue to top the list of most in-demand treatments for  patients. With many safe and effective...
02/23/2023

and filler injections continue to top the list of most in-demand treatments for patients. With many safe and effective options available, new and emerging products are also showing promise. Nashville, Tenn.-based Michael Gold, MD shares his insights about trends, what’s new, and what potential developments he’s excited about. https://bit.ly/3lgS54S

Apremilast may be an “incredibly promising” treatment for alcohol use disorder, according to a new study in The Journal ...
02/22/2023
Study: Psoriasis Medicine May Help Treat Alcohol Use Disorder - Practical Dermatology

Apremilast may be an “incredibly promising” treatment for alcohol use disorder, according to a new study in The Journal of Clinical Investigation.

On average, the people who took reduced their alcohol intake by more than half — from five drinks per day to two.

People who took apremilast reduced their alcohol intake by more than half — from five drinks per day to two.

Energy-based devices have revolutionized cosmetic , and the already hot category is experiencing a growth spurt.Todd Sch...
02/21/2023

Energy-based devices have revolutionized cosmetic , and the already hot category is experiencing a growth spurt.

Todd Schlesinger, MD, founder and medical director of the Dermatology & Laser Center of Charleston as well as the Clinical Research Center of the Carolinas sat down with Practical Dermatology® magazine to discuss his go-to devices and the growing role they play in his practice. https://bit.ly/41lnlAi

In this brief article, we aim to outline best practices and principles for maximizing efficiency in meetings from a  per...
02/21/2023

In this brief article, we aim to outline best practices and principles for maximizing efficiency in meetings from a perspective. The goal is not to criticize well-intentioned efforts but to revisit the purpose of meetings and to offer constructive and practical suggestions to improve meeting efficiency. Ahead, we share personal experiences, anecdotes, and a variety of opinions, supplemented with external evidence from the literature, where available. https://bit.ly/3XNHo78

Notalgia paresthetica—a nerve disorder characterized by a persistent itch in the upper back—is a common and underdiagnos...
02/19/2023

Notalgia paresthetica—a nerve disorder characterized by a persistent itch in the upper back—is a common and underdiagnosed condition worldwide. To date, there are no U.S. FDA-approved treatments specifically targeting this disorder.

But a new study in the The New England Journal of Medicine suggests that patients experiencing the moderate-to-severe itching associated with the disorder could potentially get relief with oral difelikefalin. The research was led by investigators at the Icahn School of Medicine at Mount Sinai. https://bit.ly/3S80xzH

Cetaphil announced it is launching a new initiative this month that aims to raise awareness of the connection between ou...
02/18/2023
Cetaphil Launches Initiative to Raise Awareness of Connection Between Clothing and Sensitive Skin - Practical Dermatology

Cetaphil announced it is launching a new initiative this month that aims to raise awareness of the connection between our clothes and skin. The initiative includes a partnership with Hillary Taymour, designer and founder of fashion house Collina Strada, and board-certified dermatologist at Spring Street Dermatology, Sapna Rao Palep, MD, Dermatologist - Leading Physicians of the World , MD.

Cetaphil announced it is launching a new initiative this month that aims to raise awareness of the connection between our clothes and skin. The initia

Dermavant Sciences has completed patient enrollment in its ADORING 1 and 2 Phase 3 clinical trials of VTAMA (tapinarof) ...
02/15/2023

Dermavant Sciences has completed patient enrollment in its ADORING 1 and 2 Phase 3 clinical trials of VTAMA (tapinarof) cream, 1% for the topical treatment of atopic dermatitis (AD) in adults and children as young as 2 years old. https://bit.ly/3S0chUS

The U.S. General Services Administration has recommended DermTech‘s foundational assay included in the DermTech Melanoma...
02/14/2023
DermTech Melanoma Test Recommended for Coverage by the Veterans Health Administration - Practical Dermatology

The U.S. General Services Administration has recommended DermTech‘s foundational assay included in the DermTech Melanoma Test (DMT) for coverage by the Veterans Health Administration (VHA), according to a company news release.

This coverage recommendation makes the foundational assay of the DMT available to the VHA’s over 9 million enrolled veterans.

The U.S. General Services Administration has recommended DermTech‘s foundational assay included in the DermTech Melanoma Test (DMT) for coverage

02/14/2023

See Full Prescribing Information: https://bit.ly/SOTYKTUpi

SOTYKTU (deucravacitinib) is a once-daily treatment option for appropriate patients. See the efficacy and safety data >> http://bit.ly/3VmFmtw

This ad is brought to you by Bristol Myers Squibb.

Longer-term treatment with povorcitinib 75 mg resulted in sustained and durable efficacy across all treatment arms in a ...
02/14/2023
Povorcitinib Produces Lasting Results in HS - Practical Dermatology

Longer-term treatment with povorcitinib 75 mg resulted in sustained and durable efficacy across all treatment arms in a phase 2 study of hidradenitis suppurativa (HS) patients.

Povorcitinib is an oral JAK1 inhibitor. These data were presented as an oral presentation at the 12th Conference of the European Hidradenitis Suppurativa Foundation, held from February 8 to 10, 2023, in Florence, Italy.

Longer-term treatment with povorcitinib 75 mg resulted in sustained and durable efficacy across all treatment arms in a phase 2 study.

This  (April), the National Rosacea Society (NRS) is highlighting the importance of consistency and patience when trying...
02/09/2023

This (April), the National Rosacea Society (NRS) is highlighting the importance of consistency and patience when trying new therapies.

“Rosacea has no cure, but the signs and symptoms can go into remission through a combination of medical therapy and lifestyle changes,” says Dr. Estee Williams, assistant clinical professor of at Mount Sinai Medical Center, in a news release. “The timeline to achieve remission will be different for each individual depending on the disease presentation and severity. The key is consistency and patience."

Read more: https://bit.ly/3IbMd5T

Despite fears of a looming recession, the market for  treatments remains strong, and the prospect of new entries is keep...
02/08/2023

Despite fears of a looming recession, the market for treatments remains strong, and the prospect of new entries is keeping consumer demand healthy. As a new year starts, it’s smart to consider promoting some new options to drive consumer excitement and volume. Here, we report five hot trends from Wendy Lewis & Co Ltd: https://bit.ly/3x3gcql

Neurotoxin and filler injections continue to top the list of most in-demand treatments for aesthetic patients. With many...
02/07/2023

Neurotoxin and filler injections continue to top the list of most in-demand treatments for aesthetic patients. With many safe and effective options available, new and emerging products are also showing promise. Nashville, TN-based Michael H. Gold, MD shares his insights about trends, what’s new, and what potential developments he’s excited about. https://bit.ly/3lgS54S

Bio-Oil USA is rolling out a month-long campaign in celebration of February's Body Positivity Month to encourage self-lo...
02/06/2023
Bio-Oil Celebrates Body Confidence Through Body Positivity Month Campaign - Practical Dermatology

Bio-Oil USA is rolling out a month-long campaign in celebration of February's Body Positivity Month to encourage self-love, promote body confidence, and highlight the role that Bio-Oil plays in helping people to love their stretch marks due to pregnancy, to scars from surgical procedures.

Bio-Oil is partnering with a diverse roster of social media influencers to share how they view and take care of their bodies – and the strength they represent – on TikTok and Instagram.

Darier disease (DD) is a rare, autosomal dominant disorder with an approximated prevalence of one to two cases per 100,0...
02/05/2023

Darier disease (DD) is a rare, autosomal dominant disorder with an approximated prevalence of one to two cases per 100,000 people. It is caused by mutations in the ATP2A2 gene coding for the SarcoEndoplasmic Reticulum Calcium-ATPase 2 (SERCA2) pump, which leads to desmosome protein dysfunction and abnormal keratinization. Approximately 10% of cases represent the localized form of DD, causing a mosaic pattern of skin involvement. Several variants of localized DD have been reported, including unilateral, zosteriform, segmental, and linear.

Here, Lacey Zimmerman, MD; Neha Chandan MD, MPH; and Sheryl Hoyer, MD, present a rare case of linear DD: https://bit.ly/3HACBA3

Avero Diagnostics announced the US launch of AMBLor, a laboratory test for the identification of early-stage melanomas a...
02/05/2023
Avero Diagnostics Launches Test for Early-Stage Melanoma Progression - Practical Dermatology

Avero Diagnostics announced the US launch of AMBLor, a laboratory test for the identification of early-stage melanomas at low risk of progression.

AMBLor technology identifies the presence of two prognostic biomarker proteins, AMBRA1 and loricrin, in the skin overlying the tumor, according to Avero.

Avero Diagnostics announced the US launch of AMBLor, a laboratory test for the identification of early-stage melanomas at low risk of progression.

New biomarkers to improve  detection and avoid delays in treatment are being developed by researchers at the University ...
02/03/2023
New Biomarkers May Help Advance Melanoma Detection - Practical Dermatology

New biomarkers to improve detection and avoid delays in treatment are being developed by researchers at the University of South Australia.

“ exhibit a wide range of sizes, shapes and growth, which can resemble numerous benign and other malignant skin lesions,” says UniSA PhD candidate Giang Lam in a new paper published in Molecular Diagnosis and Therapy.

The new detection methods based on abnormal markers in the endosomal system, which flags melanoma growth.

Medical video games increase the competence and clinical decision-making of practicing physicians, a new study by LEVEL ...
02/02/2023

Medical video games increase the competence and clinical decision-making of practicing physicians, a new study by LEVEL EX shows. Doctors not only showed clinical improvement while playing the games, but also demonstrated improvement in clinical decision making long after gameplay. https://bit.ly/3l5ZGDf

The Bundy Group wanted to analyze the key questions and unpack the positives and considerations of accepting an unsolici...
02/01/2023

The Bundy Group wanted to analyze the key questions and unpack the positives and considerations of accepting an unsolicited offer versus running a competitive process managed by an investment banker. Explore them here: https://bit.ly/3Yy82lB

Slightly more than 7% of adults and nearly 11% of kids had  in 2021, according to two new reports in the CDC ’s National...
02/01/2023

Slightly more than 7% of adults and nearly 11% of kids had in 2021, according to two new reports in the CDC ’s National Center for Health Statistics Data Brief.

While the new research wasn’t designed to determine if eczema is on the rise, the condition does appear to be more prevalent than in past years. Continue reading: https://bit.ly/3JvAPml

The phenomenon of lanolin allergenicity is the focus of the Contact Allergen of the Year article in Dermatitis. Lanolin ...
01/31/2023
Spotlight on: Lanolin Allergenicity - Practical Dermatology

The phenomenon of lanolin allergenicity is the focus of the Contact Allergen of the Year article in Dermatitis.

Lanolin and its derivatives are widely used in cosmetics and pharmaceuticals designed for topical use on skin, lips, nails, and hair, and as an ocular emollient. They also have many industrial uses. Still, lanolin’s allergenicity remains controversial, and appropriate patch testing to detect lanolin allergy remains a topic of dispute.

The phenomenon of lanolin allergenicity is the focus of the Contact Allergen of the Year article in Dermatitis.  Lanolin and its der

BCC is the most common cancer in the US. How can the best treatment pathway for individual patients be determined? Check...
01/30/2023

BCC is the most common cancer in the US. How can the best treatment pathway for individual patients be determined? Check out this multimedia and to learn more! View here: https://bit.ly/3GGOk0T

Bioprinted artificial skin can be used in cosmetics and drug testing, a new study shows.For the study, researchers compa...
01/29/2023
Study: 3D-printed Artificial Skin Can Be Used in Cosmetics and Drug Testing - Practical Dermatology

Bioprinted artificial skin can be used in cosmetics and drug testing, a new study shows.

For the study, researchers compared the conventional mimetic model based on manual pipetting with extrusion bioprinting, which “allows the in vitro reconstruction of a more relevant and representative model of human skin.”

The biomimetic material can be produced on a large scale, reducing animal testing by the cosmetics and pharmaceutical industries.

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Jeffery A Bedard, Crown's President and CEO, recently sat down with Practical Dermatology to talk about consolidations in the aesthetics market and how Crown remains focused on partnering with practices for long-term success. In addition, Jeff speaks to Crown's accomplishments over the past year and let us in on the best advice he has ever received from one of his own employees.



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https://practicaldermatology.com/news/phase-3-psoaring-3-long-term-extension-study-data-positive-for-tapinarof-cream?c4src=home:feed

Thankful to all of our patients who took part in the Psoaring clinical trials at Johnson Dermatology to help bring Vtama to market. This cream is the first novel cream FDA approved for psoriasis in our generation. Johnson DermatologyPractical Dermatology
Thank you to Practical Dermatology for publishing our exciting announcement about the launch of the Global Dermatology Coalition.
: dermatologist Karl Saardi, MD, discussed new and emerging treatments for blistering diseases at the American Academy of Dermatology annual meeting. Watch now at Practical Dermatology: https://bit.ly/387E7vi
Congratulations to Vishal Patel, MD, assistant professor of dermatology at The George Washington University School of Medicine & Health Sciences and director of cutaneous oncology at The George Washington University Cancer Center, who was named the interim editor of Practical Dermatology's Digital Practice column! https://bit.ly/3r18RoG
We are proud to partner with Practical Dermatology as we continue our Medical Education Series, hosted by geneticist Thomas Hitchcock, Ph.D., Chief Science Officer at Crown Laboratories. Visit PD's online portal today to access our range of medical education resources, including:

* Our Beauty & the Bacteria docuseries, which takes you inside the world of the skin microbiome;

* The Skin Science Podcast, a monthly podcast that covers hot topics relating to skin health; and,

* Several articles penned by Dr. Hitchcock that will challenge the way you think about skin microbiome care.



https://fal.cn/3nqxr
Practical Dermatology highlighted the Outstanding Leadership in Dermatology Education and Research Award presented to Joel L. Cohen, MD at ODAC 2022!

Congratulations again, Dr. Cohen!

https://practicaldermatology.com/news/odac-and-jdd-honor-dr-joel-l-cohen?c4src=home:feed
in the News — Mathew Avram, MD, JD, sat down with Practical Dermatology to reflect on dermatology in 2021.
Dr. Amy Brodsky has contributed another article to Practical Dermatology, this time focused on safety.

Her key takeaways:
☀️ Sunscreens are safe! If you are concerned about ingredients, then use ones with oxide and dioxide.
☀️ Sunscreen must be applied correctly in order to work (the sprays can be tricky!)
☀️ Sunscreen is only one part of a good sun safety plan (hint- seek shade!)
☀️ Kids need to know sun safety!

https://practicaldermatology.com/articles/2021-dec/update-on-uv-safety?c4src=issue:feed
Great to see DermTech featured in Practical Dermatology on technology for detecting skin cancer. Early detection is key when it comes to ending melanoma deaths and the DermTech Melanoma Test is the only non-invasive test to accurately detect the presence of this deadly skin cancer. And a great reminder for us all to always check our skin, use sun protection and see a derm regularly!

https://practicaldermatology.com/articles/2021-sept/using-technology-to-detect-skin-cancer-profile-lesions-and-streamline-your-practice?c4src=home:feed
As augmented intelligence evolves, here are 7 things every dermatologist should know about its potential and its limitations. Practical Dermatology https://practicaldermatology.com/articles/2021-sept/what-every-dermatologist-should-know-about-ai/pdf
Don't miss the most recent episodes of Coping with COVID-19! Our panel of aesthetic physicians reconvened for an update on current safety protocols in their practices, their thoughts on mask and vaccine mandates, travel to lives meetings, and more! Michael Gold, MD of Gold Skin Care Center led the discussions with Dr Doris Day; Dr. Mark S. Nestor; Dr. Joel Schlessinger; and Dr. Amy Taub https://hubs.ly/H0VP33t0

Practical Dermatology
“Forget textbooks, lectures, and labs. Future dermatologists may soon be learning in a whole new (and likely much more fun) way.”

Practical Dermatology explores how Top Derm’s game design can help improve the way sharpen their skills and stay up to date. Read more: http://ow.ly/BxNV50FWcKT
Curious what people are saying about our new medical game Top Derm? Dr. Shraddha Desai joins Practical Dermatology’s DermWireTV to discuss our latest medical video game, Top Derm, and shares the benefits of accessing dermatology resources from her mobile phone.

“I find it enjoyable. You don’t have to lug around your book or your journal, or anything with you. It’s something you carry around with you all the time”

Hear what else Dr. Desai has to say and watch the entire episode here: http://ow.ly/flXA50FKog9
It’s a great time to be a pedi derm! Wondering just how great? Hear it firsthand from SPD’s own Dr. Mercedes Gonzalez when she spoke to Practical Dermatology’s DermWireTV about the 2020 Pediatric Dermatology Physician Compensation Report. Watch the full clip here: http://bit.ly/DWTVsalaries
“Each of us has biases, and an important first step is to acknowledge what those are and be introspective about how we can address them for the betterment of ourselves and those that we interact with, particularly our patients,” – Dr. Nada Elbuluk, Director of Clinical Impact at VisualDx.
Learn more in Practical Dermatology on how healthcare professionals can overcome cognitive biases: https://practicaldermatology.com/articles/2021-may/confronting-biases-to-improve-patient-care?c4src=home:feed
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