Practical Neurology

09/20/2025

-1RA therapy may offer an alternative management strategy for idiopathic intracranial hypertension, according to a large-scale cohort study published in JAMA Neurology.
https://ow.ly/orzW50WZ4BC
American Headache Society® American Academy of Neurology (AAN) American College of Physicians (ACP) American Heart Association

Results from a large retrospective study published in JAMA Neurology suggest that glucagon-like peptide-1 receptor agonist (GLP-1 RA) therapy may offer be…

09/20/2025

The U.S. Food and Drug Administration granted Breakthrough Therapy designation to ION582, an RNA-targeted antisense drug under investigation for the treatment of syndrome.
https://ow.ly/HiHE50WZzHe
Child Neurology Society American Academy of Neurology (AAN) American Epilepsy Society International Parkinson and Movement Disorder Society

The Food and Drug Administration (FDA) has granted Breakthrough Therapy designation to ION582 (Ionis Pharmaceuticals, Carlsbad, CA) for the treatment of A…

09/19/2025

📢 New Issue Now Live: Medical Editor Dr. Danette Taylor (Trinity Health Grand Rapids) presents a deep dive on managing non-motor symptoms of 's, including , , dysfunction, & more.

Read our new issue today: https://ow.ly/OOk850WZ4RV
The Michael J. Fox Foundation for Parkinson's Research International Parkinson and Movement Disorder Society Parkinson's Foundation Trinity Health System

09/19/2025

The U.S. Food and Drug Administration expanded the indication for to include a granule and capsule formulation for the treatment of pediatric patients aged ≥1 year with type 1 and symptomatic, inoperable plexiform .
https://ow.ly/mN5n50WZzES
Society for Neuro-Oncology, USA American Academy of Neurology (AAN) American College of Physicians (ACP) Child Neurology Society AstraZeneca

The Food and Drug Administration (FDA) announced the expanded approval of Koselugo (selumetinib; AstraZeneca, Wilmington, DE) to include pediatric patient…

09/14/2025

has been added to the National Comprehensive Cancer Network Clinical Practice Guidelines in as a category 2A recommended treatment for H3 K27M-mutant diffuse .
https://ow.ly/BRoZ50WVnlj
Society for Neuro-Oncology, USA American Academy of Neurology (AAN) Jazzpharma American Society of Clinical Oncology

The National Comprehensive Cancer Network (NCCN; Plymouth Meeting, PA) has included Modeyso (dordaviprone; Jazz Pharmaceuticals, Dublin, Ireland) in its C…

09/13/2025

New Podcast Episode: Catherine Auriemma, MD, MSHP & Carolyn Chow, MD () provide insights on 's therapies from interviews with patients and caregivers.
https://ow.ly/U2LT50WVnaT

09/12/2025

New Podcast Episode: Catherine Auriemma, MD, MSHP and Carolyn Chow, MD (Perelman School of Medicine at the University of Pennsylvania) provide insights on 's therapies from interviews with patients and caregivers.
https://ow.ly/tl3W50WVrIh
American Academy of Neurology (AAN) Alzheimer's Association

This episode explores groundbreaking qualitative research from the University of Pennsylvania on patient and caregiver perspectives in Alzheimer disease. Catherine Auriemma, MD, MSHP, Perelman School of Medicine, University of Pennsylvania, Philadelphia,...

09/12/2025

The U.S. Food and Drug Administration has announced that adverse events will now be reported on a daily basis, rather than quarterly.
https://ow.ly/mlvy50WVrFt
American Academy of Neurology (AAN) American College of Physicians (ACP)

The Food and Drug Administration (FDA) announced that adverse event information from the FDA Adverse Event Reporting System (FAERS) will now be published …

09/11/2025

For electrical stimulation mapping of the brain before surgery, a new procedure involving naturalistic conversation may offer a reliable alternative to traditional methods that use repetitive tasks.
https://ow.ly/QoCp50WVmQp
American Epilepsy Society American Academy of Neurology (AAN) American Association of Neurological Surgeons

A study published in Annals of Neurology reports that naturalistic conversation may provide a reliable alternative to standard task-based procedures for e…

09/11/2025

Practical Neurology is a finalist for 4 categories of the FOLIO: 2025 Eddie & Ozzie awards, with entries including our care issue, an article on the Salem Witch Trial, our in Motion animation series, and issue covers. Winners will be announced in October.

09/10/2025

Subcutaneous ( ) to be reviewed by U.S. Food and Drug Administration as a starting dose for people with early 's.
https://ow.ly/wVoG50WUaTo
Alzheimer's Association American Academy of Neurology (AAN) Eisai US Biogen

Eisai (Tokyo, Japan) and Biogen (Cambridge, MA) have initiated the rolling submission of a supplemental Biologics License Application (sBLA) to the Food a…

09/09/2025

age and type of menopausal hormone therapy were both linked to domains of memory performance in results of a study published in Neurology Journal.
https://ow.ly/nHTm50WUaxe
American Academy of Neurology (AAN) American College of Physicians (ACP) Alzheimer's Association

Results of a study published in Neurology suggest that the type of estradiol-based hormone therapy taken after menopause may be associated with specific d…