Practical Neurology

Practical Neurology A monthly publication that strives to enhance quality of care and improve the daily operation of neur

Each month, our experts explain the real-world significance of recent advances in neurologic science and offer step-by-step advice on how to overcome the clinical and business challenges neurologists face. Our straightforward, how-to articles give neurologists tools they can put into practice right away.

01/04/2026

Research presented at found that videos with misinformation about treatment receive far more engagement than evidence-based content.
https://ow.ly/fhyR50XReJV
American Epilepsy Society American Academy of Neurology (AAN)

An analysis of TikTok videos revealed that content with misinformation about epilepsy treatment draws substantially more engagement than evidence-based co…

01/03/2026

The contract for Walter Koroshetz, MD, Director of the National Institute of Neurological Disorders and Stroke - NINDS has been terminated. Dr. Koroshetz will step down after 10 years in the role.
https://ow.ly/x9uR50XReFv
National Institutes of Health (NIH) American Academy of Neurology (AAN)

The contract for Walter Koroshetz, MD, as Director of the National Institute of Neurological Disorders and Stroke (NINDS) has not been renewed, ending his…

01/02/2026

The U.S. Food and Drug Administrationgranted Breakthrough Therapy Designation to for —data showed significant functional improvement—with an NDA submission planned for early 2026.
https://ow.ly/2jy550XReHE
International Essential Tremor Foundation International Parkinson and Movement Disorder Society American Academy of Neurology (AAN)

The Food and Drug Administration (FDA) has granted Breakthrough Therapy Designation to ulixacaltamide (Praxis Precision Medicines, Boston, MA) for the tre…

01/01/2026

New guidelines update recommendations for migraine care, recommending IV and greater occipital nerve blocks—and discouraging opioid use—for acute treatment. Read more:

Dr. Tatum discusses   interpretation pitfalls, strategies to reduce misdiagnosis, and emerging uses of  -assisted   to i...
12/31/2025

Dr. Tatum discusses interpretation pitfalls, strategies to reduce misdiagnosis, and emerging uses of -assisted to identify brain tumor–related signals and potentially predict recurrence earlier than MRI.
https://ow.ly/CXwZ50XQbha
Mayo Clinic American Epilepsy Society

William Tatum, DO, Mayo Clinic, Jacksonville, FL, details how ECoG along with AI can help with the identification of epileptic foci.

12/30/2025

📋 Your EHR notes may hold more insight than you think for care.
At , Dr. Pierre D’Haese ( ) showed how AI analysis of narrative EHR data can help identify patients who may benefit from timely MRI, EEG, or neuropsych testing.
https://ow.ly/glQZ50XQb3a
American Epilepsy Society

Pierre D’Haese, PhD, West Virginia University Rockefeller Neuroscience Institute, Morgantown, WV, discuses how AI-driven automation can surface missing MR…

📊 What does   nerve stimulation therapy mean for patients with drug-resistant  ? 🔗 Dive into the full results from the C...
12/30/2025

📊 What does nerve stimulation therapy mean for patients with drug-resistant ? 🔗 Dive into the full results from the CORE-VNS study from : https://ow.ly/G5hQ50XQ8RA
American Epilepsy Society American Academy of Neurology (AAN) Epilepsy Foundation of America LivaNova

Maxine Dibue, PhD, LivaNova, London, UK, details 36-month prospective registry data on adjunctive vagus nerve stimulation in patients with drug-resistant …

Are We Watching Some   Patients Closely Enough? New   data suggest patients with comorbid   experience earlier treatment...
12/29/2025

Are We Watching Some Patients Closely Enough? New data suggest patients with comorbid experience earlier treatment failure after starting antiseizure meds—often within months.
📊 Claims-based evidence
🧠 Big implications for screening & follow-up
👉 Click through to learn more: https://ow.ly/nrN150XPn8R

Samuel W. Terman, MD, University of Michigan, Ann Arbor, MI, provides details about a new study based on claims data showing how depression affects treatm…

New podcast episode: The Neurologist’s Role in Brain Tumor Care👩‍⚕️ Neurologists are on the front line of early diagnosi...
12/27/2025

New podcast episode: The Neurologist’s Role in Brain Tumor Care
👩‍⚕️ Neurologists are on the front line of early diagnosis with seizures as the presenting symptom in up to 80% of IDH-mutant gliomas.
Learn more about
✔️ Molecular testing options
✔️ New treatments
✔️ Access to clinical trials
https://ow.ly/vb8t50XP71Y

Patrick Y. Wen, MD, Dana-Farber Cancer Institute, Boston, MA, discusses current standards of care for low- and high-grade gliomas, including the importanc…

12/27/2025

Long-term VALOR/OLE results show earlier ( ) treatment in SOD1- is associated with numerically less functional decline & lower NfL vs delayed initiation, compared with natural history.
https://ow.ly/9M9Y50XOBGL
The ALS Association American Academy of Neurology (AAN) Biogen

Long-term treatment with Qalsody (tofersen; Biogen, Cambridge, MA) was associated with numerically less functional decline than expected from natural hist…

12/26/2025

A U.S. Food and Drug Administration approval expands n-BCA use to middle meningeal artery for symptomatic chronic subdural .
https://ow.ly/xb6k50XOryN
American Heart Association Endovascular Today

The Food and Drug Administration (FDA) has approved an expanded indication for the TRUFILL n-BCA Liquid Embolic System (Johnson & Johnson, Irvine, CA)…

12/25/2025

failed to meet its primary end point in primary progressive , & Sanofi will not pursue approval for . Regulatory review for is expected to extend beyond the US target action date.
https://ow.ly/GjAF50XO5ro
National Multiple Sclerosis Society The Consortium of Multiple Sclerosis Centers American Academy of Neurology (AAN) ACTRIMS

Treatment with the investigational Bruton tyrosine kinase (BTK) inhibitor tolebrutinib (Sanofi, Bridgewater, NJ) did not delay disability progression in p…

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