The Clinical Notebook

17/06/2025

LET'S TALK ABOUT DICLOFENAC AND PARACETAMOL

1. Diclofenac

Class: Nonsteroidal Anti-inflammatory Drug (NSAID)

Mechanism of Action: Inhibits cyclooxygenase (COX-1 and COX-2) enzymes, reducing prostaglandin synthesis → decreases inflammation, pain, and fever.

Indications:

Musculoskeletal pain

Arthritis (e.g., osteoarthritis, rheumatoid arthritis)

Post-operative pain

Forms: Tablets, injection, topical gel, suppositories

Side Effects:

Gastric irritation or ulcers

Renal impairment

Increased cardiovascular risk (with long-term use)

Caution: Avoid in peptic ulcer disease, kidney dysfunction, or heart disease.

2. Paracetamol (Acetaminophen)

Class: Analgesic and Antipyretic

Mechanism of Action: Inhibits prostaglandin synthesis mainly in the central nervous system, leading to pain relief and fever reduction.

Indications:

Headache

Fever

Mild to moderate pain (e.g., toothache, backache)

Forms: Tablets, syrup, suppositories, injection

Side Effects:

Generally safe at recommended doses

Hepatotoxicity (liver damage) in overdose

Caution: Use with care in liver disease; avoid alcohol during treatment.

17/06/2025

Shout out to my newest followers! Excited to have you onboard! Chawezi Chawezi

12/06/2025

An eight-year-old boy in Kansas named Gabriel Marshall was diagnosed with a rare form of brain cancer last year and surgeons were able to remove most of the tumor. The surgery left him with a nasty S-shaped scar on the side of his head.

A photo of him with his dad John is going viral. His dad, John, got a tattoo on the side of his head to match his son's scar.

Dad says Gabriel was really self-conscious after the surgery, and thought the scar made him feel "like a monster." So he got the tattoo to boost Gabriel's self-esteem and show him it's no big deal.

Then he entered a contest earlier this year called "Best Bald Dad," where guys shave their heads to support their kids while they're going through chemo. He was just named the winner on Sunday!

He posted about it on Facebook, and made it a point to say he's no better than any of the other dads who entered. And they'd ALL do anything to help their kids.

By the way, Gabriel is doing better since his surgery. His dad says he loves the tattoo, and tells everyone they're like twins now.

There's still a small portion of the tumor that the doctors couldn't get to. But Gabriel's been having MRI's every three months, and so far it hasn't gotten any bigger. - I love this story and this dad. Here'a a picture of John and his son Gabriel.

10/06/2025

Relationships don't affect your studies.
If you're dumb, you're dumb. 🤗

17/05/2025

UNDERSTANDING TENS MACHINE MOSTLY USED BY PHYSIOTHERAPISTS TO RELIEVE PAIN✍️✍️

17/05/2025

13/05/2025

HYPERTENSION

In the bustling heart of Lusaka, a 45-year-old professional juggles work, family, and the demands of daily life. Despite feeling fatigued and experiencing occasional headaches, she attributes these symptoms to stress and long hours. Unbeknownst to her, her blood pressure has been steadily rising. One day, during a routine check-up, her doctor informs her that her blood pressure is dangerously high, a condition known as hypertension.

come with me in the comments section👇👇👇

13/05/2025

Peripheral Neuropathy
is a condition resulting from damage to the peripheral nerves, which are responsible for transmitting signals between the central nervous system (the brain and spinal cord) and the rest of the body. This damage can lead to various symptoms and complications.

11/05/2025

Physio student: So, today’s patient has back pain.
Supervisor: And your plan is...?
Physio student: I told him to rest, hydrate, and pray.
Supervisor: Pray?? Are we running a physio department or a revival meeting?

Physio student: Well, I thought if the spine’s not aligned, maybe divine intervention?

Supervisor: Next time, align your notes before your faith. Start with some stretches, Mwansa

Physio student: Got it. Stretch the spine, not the theology.

10/05/2025

What Is Cerebral Palsy

Cerebral palsy (CP) is a group of permanent movement disorders caused by abnormal brain development or damage to the developing brain, affecting motor control and coordination. It is the most common motor disability in childhood. CP can result from factors before, during, or shortly after birth.

come with me in the comments section👇👇

09/05/2025

funny ward rounds are funny 😂🤣🤣

PHYSIO STUDENT: Boss, I’m ready for ward rounds today.

SUPERVISOR: Great. What’s the patient’s diagnosis in bed 3?

PHYSIO STUDENT: Umm… they’re very comfortable and sleeping well?

SUPERVISOR: That’s not a diagnosis, that’s a hotel review!

PHYSIO STUDENT: Sorry boss, I forgot my notebook.
SUPERVISOR: Your brain should be your notebook! Right now, it’s looking like a blank page!
PHYSIO STUDENT: Should I just follow and nod aggressively like I understand?

SUPERVISOR: Exactly. But nod in medical terms!

Ahh 🤦🏿‍♂️🤣🤣